{"id":"https://openalex.org/W2048864962","doi":"https://doi.org/10.1016/0167-4838(87)90140-3","title":"Alterations in the carbohydrate moiety of alpha-1-acid glycoprotein purified from human cirrhotic ascitic fluid","display_name":"Alterations in the carbohydrate moiety of alpha-1-acid glycoprotein purified from human cirrhotic ascitic fluid","publication_year":1987,"publication_date":"1987-07-01","ids":{"openalex":"https://openalex.org/W2048864962","doi":"https://doi.org/10.1016/0167-4838(87)90140-3","mag":"2048864962","pmid":"https://pubmed.ncbi.nlm.nih.gov/3297164"},"language":"en","primary_location":{"id":"doi:10.1016/0167-4838(87)90140-3","doi":"https://doi.org/10.1016/0167-4838(87)90140-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0167-4838(87)90140-3","pdf_url":null,"source":{"id":"https://openalex.org/S4394735818","display_name":"Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology","issn_l":"0167-4838","issn":["0167-4838","1879-2588"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["norway-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053665359","display_name":"Daniel R. Biou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Daniel Biou","raw_affiliation_strings":["Centre d'Etudes Pharmaceutiques et Biologiques, CNRS UA 040622, Ch\u00e2tenay-Malabry France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre d'Etudes Pharmaceutiques et Biologiques, CNRS UA 040622, Ch\u00e2tenay-Malabry France","institution_ids":["https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031152482","display_name":"Daniel Konan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Daniel Konan","raw_affiliation_strings":["Centre d'Etudes Pharmaceutiques et Biologiques, CNRS UA 040622, Ch\u00e2tenay-Malabry France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre d'Etudes Pharmaceutiques et Biologiques, CNRS UA 040622, Ch\u00e2tenay-Malabry France","institution_ids":["https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068161204","display_name":"Jeanne F\u00e9ger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jeanne F\u00e9ger","raw_affiliation_strings":["Centre d'Etudes Pharmaceutiques et Biologiques, CNRS UA 040622, Ch\u00e2tenay-Malabry France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre d'Etudes Pharmaceutiques et Biologiques, CNRS UA 040622, Ch\u00e2tenay-Malabry France","institution_ids":["https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111436600","display_name":"Jean AGNERAY","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean Agneray","raw_affiliation_strings":["Centre d'Etudes Pharmaceutiques et Biologiques, CNRS UA 040622, Ch\u00e2tenay-Malabry France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre d'Etudes Pharmaceutiques et Biologiques, CNRS UA 040622, Ch\u00e2tenay-Malabry France","institution_ids":["https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yves Leroy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Yves Leroy","raw_affiliation_strings":["Laboratoire de Chimie Biologique, et Unit\u00e9 Associ\u00e9e au CNRS No. 217, Universit\u00e9 des Sciences et Techniques de Lille Flandres Artois, Villeneuve D'Ascq France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Chimie Biologique, et Unit\u00e9 Associ\u00e9e au CNRS No. 217, Universit\u00e9 des Sciences et Techniques de Lille Flandres Artois, Villeneuve D'Ascq France","institution_ids":["https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017328270","display_name":"Pascal Cardon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Pascal Cardon","raw_affiliation_strings":["Laboratoire de Chimie Biologique, et Unit\u00e9 Associ\u00e9e au CNRS No. 217, Universit\u00e9 des Sciences et Techniques de Lille Flandres Artois, Villeneuve D'Ascq France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Chimie Biologique, et Unit\u00e9 Associ\u00e9e au CNRS No. 217, Universit\u00e9 des Sciences et Techniques de Lille Flandres Artois, Villeneuve D'Ascq France","institution_ids":["https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016544417","display_name":"Bernard Fournet","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Bernard Fournet","raw_affiliation_strings":["Laboratoire de Chimie Biologique, et Unit\u00e9 Associ\u00e9e au CNRS No. 217, Universit\u00e9 des Sciences et Techniques de Lille Flandres Artois, Villeneuve D'Ascq France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Chimie Biologique, et Unit\u00e9 Associ\u00e9e au CNRS No. 217, Universit\u00e9 des Sciences et Techniques de Lille Flandres Artois, Villeneuve D'Ascq France","institution_ids":["https://openalex.org/I1294671590"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110055764","display_name":"Genevi\u00e8ve Durand","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Genevi\u00e8ve Durand","raw_affiliation_strings":["Centre d'Etudes Pharmaceutiques et Biologiques, CNRS UA 040622, Ch\u00e2tenay-Malabry France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre d'Etudes Pharmaceutiques et Biologiques, CNRS UA 040622, Ch\u00e2tenay-Malabry France","institution_ids":["https://openalex.org/I1294671590"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5110055764"],"corresponding_institution_ids":["https://openalex.org/I1294671590"],"apc_list":null,"apc_paid":null,"fwci":1.0455,"has_fulltext":false,"cited_by_count":40,"citation_normalized_percentile":{"value":0.75658713,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"913","issue":"3","first_page":"308","last_page":"312"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10835","display_name":"Carbohydrate Chemistry and Synthesis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alpha-1-acid-glycoprotein","display_name":"alpha-1-acid glycoprotein","score":0.9929999709129333},{"id":"https://openalex.org/keywords/liver-cirrhosis","display_name":"liver cirrhosis","score":0.7490000128746033},{"id":"https://openalex.org/keywords/ascitic-fluid","display_name":"ascitic fluid","score":0.9309999942779541},{"id":"https://openalex.org/keywords/carbohydrate-moiety","display_name":"carbohydrate moiety","score":0.6340000033378601},{"id":"https://openalex.org/keywords/fucosyl-residues","display_name":"fucosyl residues","score":0.8450000286102295},{"id":"https://openalex.org/keywords/sialic-acid","display_name":"sialic acid","score":0.8629999756813049},{"id":"https://openalex.org/keywords/oligosaccharide-branching","display_name":"oligosaccharide branching","score":0.8240000009536743},{"id":"https://openalex.org/keywords/glycosylation","display_name":"glycosylation","score":0.5370000004768372}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7765233516693115},{"id":"https://openalex.org/C2994067411","wikidata":"https://www.wikidata.org/wiki/Q125264","display_name":"Molar ratio","level":3,"score":0.6967388987541199},{"id":"https://openalex.org/C2778977261","wikidata":"https://www.wikidata.org/wiki/Q11358","display_name":"Carbohydrate","level":2,"score":0.6522485613822937},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.642912745475769},{"id":"https://openalex.org/C149629883","wikidata":"https://www.wikidata.org/wiki/Q660926","display_name":"Fraction (chemistry)","level":2,"score":0.617239773273468},{"id":"https://openalex.org/C108625454","wikidata":"https://www.wikidata.org/wiki/Q187126","display_name":"Glycoprotein","level":2,"score":0.6125233769416809},{"id":"https://openalex.org/C2777108408","wikidata":"https://www.wikidata.org/wiki/Q11002","display_name":"Sugar","level":2,"score":0.6075328588485718},{"id":"https://openalex.org/C206175624","wikidata":"https://www.wikidata.org/wiki/Q595731","display_name":"Branching (polymer chemistry)","level":2,"score":0.5846859812736511},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.4909568130970001},{"id":"https://openalex.org/C202271784","wikidata":"https://www.wikidata.org/wiki/Q189218","display_name":"Molar","level":2,"score":0.46709388494491577},{"id":"https://openalex.org/C2776568683","wikidata":"https://www.wikidata.org/wiki/Q23005640","display_name":"Moiety","level":2,"score":0.45740747451782227},{"id":"https://openalex.org/C100817775","wikidata":"https://www.wikidata.org/wiki/Q134219","display_name":"Polysaccharide","level":2,"score":0.4431452453136444},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.43816015124320984},{"id":"https://openalex.org/C64943373","wikidata":"https://www.wikidata.org/wiki/Q2651003","display_name":"Alpha (finance)","level":4,"score":0.42501574754714966},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.20957505702972412},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13136637210845947},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.058343738317489624},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C49453240","wikidata":"https://www.wikidata.org/wiki/Q1592163","display_name":"Construct validity","level":3,"score":0.0},{"id":"https://openalex.org/C2775944032","wikidata":"https://www.wikidata.org/wiki/Q22907659","display_name":"Patient satisfaction","level":2,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D001202","descriptor_name":"Ascitic Fluid","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D002240","descriptor_name":"Carbohydrate Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002241","descriptor_name":"Carbohydrates","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D002846","descriptor_name":"Chromatography, Affinity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007158","descriptor_name":"Immunologic Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008745","descriptor_name":"Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009961","descriptor_name":"Orosomucoid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/0167-4838(87)90140-3","doi":"https://doi.org/10.1016/0167-4838(87)90140-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0167-4838(87)90140-3","pdf_url":null,"source":{"id":"https://openalex.org/S4394735818","display_name":"Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology","issn_l":"0167-4838","issn":["0167-4838","1879-2588"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["norway-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology","raw_type":"journal-article"},{"id":"pmid:3297164","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3297164","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et biophysica acta","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8048999905586243}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322892","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73"},{"id":"https://openalex.org/F4320327336","display_name":"Vlaamse regering","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1487145807","https://openalex.org/W1545076715","https://openalex.org/W1603727416","https://openalex.org/W1646941904","https://openalex.org/W1748902457","https://openalex.org/W1954229558","https://openalex.org/W1965413508","https://openalex.org/W1978004329","https://openalex.org/W1982186552","https://openalex.org/W2005167711","https://openalex.org/W2007552508","https://openalex.org/W2010485836","https://openalex.org/W2011606413","https://openalex.org/W2012756035","https://openalex.org/W2037198206","https://openalex.org/W2060123467","https://openalex.org/W2067255302","https://openalex.org/W2083505970","https://openalex.org/W2084037895","https://openalex.org/W2086684985","https://openalex.org/W2100837269","https://openalex.org/W2112389369","https://openalex.org/W2127170526","https://openalex.org/W4247408138"],"related_works":["https://openalex.org/W2050948629","https://openalex.org/W2058681180","https://openalex.org/W95535224","https://openalex.org/W620879","https://openalex.org/W2099097561","https://openalex.org/W2057691789","https://openalex.org/W2064987693","https://openalex.org/W2006267137","https://openalex.org/W2624984355","https://openalex.org/W2045698620"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}