{"id":"https://openalex.org/W2048637808","doi":"https://doi.org/10.3109/00365516909080131","title":"Atypical Lactate Dehydrogenase Isoenzyme Pattern Caused by Immunoglobulin G Interaction","display_name":"Atypical Lactate Dehydrogenase Isoenzyme Pattern Caused by Immunoglobulin G Interaction","publication_year":1969,"publication_date":"1969-01-01","ids":{"openalex":"https://openalex.org/W2048637808","doi":"https://doi.org/10.3109/00365516909080131","mag":"2048637808","pmid":"https://pubmed.ncbi.nlm.nih.gov/5374923"},"language":"en","primary_location":{"id":"doi:10.3109/00365516909080131","doi":"https://doi.org/10.3109/00365516909080131","is_oa":false,"landing_page_url":"https://doi.org/10.3109/00365516909080131","pdf_url":null,"source":{"id":"https://openalex.org/S5501027","display_name":"Scandinavian Journal of Clinical and Laboratory Investigation","issn_l":"0036-5513","issn":["0036-5513","1502-7686"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scandinavian Journal of Clinical and Laboratory Investigation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111770341","display_name":"C.-O. Kindmark","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"C.-O. Kindmark","raw_affiliation_strings":["The Department of Clinical Chemistry, University of Lund, Malm\u00f6 General Hospital, Malm\u00f6, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Department of Clinical Chemistry, University of Lund, Malm\u00f6 General Hospital, Malm\u00f6, Sweden","institution_ids":["https://openalex.org/I187531555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5111770341"],"corresponding_institution_ids":["https://openalex.org/I187531555"],"apc_list":null,"apc_paid":null,"fwci":4.6095,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.94136292,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"24","issue":"1","first_page":"49","last_page":"53"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.9824000000953674,"subfield":{"id":"https://openalex.org/subfields/3607","display_name":"Medical Laboratory Technology"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.9824000000953674,"subfield":{"id":"https://openalex.org/subfields/3607","display_name":"Medical Laboratory Technology"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.00570000009611249,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12068","display_name":"Neonatal Health and Biochemistry","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lactate-dehydrogenase-isoenzymes","display_name":"lactate dehydrogenase isoenzymes","score":0.9419999718666077},{"id":"https://openalex.org/keywords/igg","display_name":"IgG","score":0.9549999833106995},{"id":"https://openalex.org/keywords/protein-protein-interaction","display_name":"protein-protein interaction","score":0.7630000114440918},{"id":"https://openalex.org/keywords/antibody-avidity","display_name":"antibody avidity","score":0.6769999861717224},{"id":"https://openalex.org/keywords/protein-complex-dissociation","display_name":"protein complex dissociation","score":0.6119999885559082}],"concepts":[{"id":"https://openalex.org/C2777318727","wikidata":"https://www.wikidata.org/wiki/Q409464","display_name":"Lactate dehydrogenase","level":3,"score":0.8003641366958618},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.6241629123687744},{"id":"https://openalex.org/C119795356","wikidata":"https://www.wikidata.org/wiki/Q407801","display_name":"Isozyme","level":3,"score":0.5975165963172913},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4786219000816345},{"id":"https://openalex.org/C2780898057","wikidata":"https://www.wikidata.org/wiki/Q79448","display_name":"Immunoglobulin G","level":3,"score":0.46445393562316895},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.433064341545105},{"id":"https://openalex.org/C2776317432","wikidata":"https://www.wikidata.org/wiki/Q412547","display_name":"Dehydrogenase","level":3,"score":0.43056702613830566},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3938789963722229},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.37085866928100586},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33413270115852356},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.1728949248790741}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001797","descriptor_name":"Blood Protein Electrophoresis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002850","descriptor_name":"Chromatography, Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D007527","descriptor_name":"Isoenzymes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007770","descriptor_name":"L-Lactate Dehydrogenase","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008970","descriptor_name":"Molecular Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.3109/00365516909080131","doi":"https://doi.org/10.3109/00365516909080131","is_oa":false,"landing_page_url":"https://doi.org/10.3109/00365516909080131","pdf_url":null,"source":{"id":"https://openalex.org/S5501027","display_name":"Scandinavian Journal of Clinical and Laboratory Investigation","issn_l":"0036-5513","issn":["0036-5513","1502-7686"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scandinavian Journal of Clinical and Laboratory Investigation","raw_type":"journal-article"},{"id":"pmid:5374923","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5374923","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scandinavian journal of clinical and laboratory investigation","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6240000128746033,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1555928652","https://openalex.org/W1994217530","https://openalex.org/W2002983094","https://openalex.org/W2019116579","https://openalex.org/W2025726222","https://openalex.org/W2026758639","https://openalex.org/W2052143219","https://openalex.org/W2057056664","https://openalex.org/W2074193041","https://openalex.org/W2406725552"],"related_works":["https://openalex.org/W2410273772","https://openalex.org/W2069938649","https://openalex.org/W1930200385","https://openalex.org/W7208250741","https://openalex.org/W406745977","https://openalex.org/W2022434261","https://openalex.org/W2282587589","https://openalex.org/W2014089370","https://openalex.org/W2082691370","https://openalex.org/W1960967081"],"abstract_inverted_index":{"A":[0],"case":[1],"of":[2,6,42],"abnormal":[3],"electrophoretic":[4],"pattern":[5],"the":[7],"serum":[8],"lactate":[9,26],"dehydrogenase":[10,27],"isoenzymes":[11],"is":[12,15],"described.":[13],"It":[14],"shown":[16],"that":[17],"this":[18],"abnormality":[19],"was":[20,39],"caused":[21],"by":[22],"an":[23],"interaction":[24],"between":[25],"and":[28],"immunoglobulin":[29],"G.":[30],"The":[31,37],"complex":[32],"dissociated":[33],"continously":[34],"during":[35],"electrophoresis.":[36],"antibody'":[38],"therefore":[40],"presumably":[41],"low":[43],"avidity.":[44]},"counts_by_year":[{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}