{"id":"https://openalex.org/W2048560883","doi":"https://doi.org/10.1007/s10695-012-9670-9","title":"Enrichment of gilthead seabream (Sparus aurata L.) diet with microalgae: effects on the immune system","display_name":"Enrichment of gilthead seabream (Sparus aurata L.) diet with microalgae: effects on the immune system","publication_year":2012,"publication_date":"2012-06-07","ids":{"openalex":"https://openalex.org/W2048560883","doi":"https://doi.org/10.1007/s10695-012-9670-9","mag":"2048560883","pmid":"https://pubmed.ncbi.nlm.nih.gov/22678706"},"language":"en","primary_location":{"id":"doi:10.1007/s10695-012-9670-9","doi":"https://doi.org/10.1007/s10695-012-9670-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10695-012-9670-9","pdf_url":null,"source":{"id":"https://openalex.org/S188633547","display_name":"Fish Physiology and Biochemistry","issn_l":"0920-1742","issn":["0920-1742","1573-5168"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fish Physiology and Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078931060","display_name":"Rebeca Cerezuela","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80180929","display_name":"Universidad de Murcia","ror":"https://ror.org/03p3aeb86","country_code":"ES","type":"education","lineage":["https://openalex.org/I80180929"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Rebeca Cerezuela","raw_affiliation_strings":["Fish Innate Immune System Group, Department of Cell Biology and Histology, Faculty of Biology, University of Murcia, 30100, Murcia, Spain","Regional Campus of International Excellence \"Campus Mare Nostrum\", University of Murcia, 30100, Murcia, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fish Innate Immune System Group, Department of Cell Biology and Histology, Faculty of Biology, University of Murcia, 30100, Murcia, Spain","institution_ids":["https://openalex.org/I80180929"]},{"raw_affiliation_string":"Regional Campus of International Excellence \"Campus Mare Nostrum\", University of Murcia, 30100, Murcia, Spain","institution_ids":["https://openalex.org/I80180929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079687943","display_name":"Francisco Antonio Guardiola","orcid":"https://orcid.org/0000-0002-1018-5446","observed_orcids":["https://orcid.org/0000-0002-1018-5446"]},"institutions":[{"id":"https://openalex.org/I80180929","display_name":"Universidad de Murcia","ror":"https://ror.org/03p3aeb86","country_code":"ES","type":"education","lineage":["https://openalex.org/I80180929"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Francisco Antonio Guardiola","raw_affiliation_strings":["Fish Innate Immune System Group, Department of Cell Biology and Histology, Faculty of Biology, University of Murcia, 30100, Murcia, Spain","Regional Campus of International Excellence \"Campus Mare Nostrum\", University of Murcia, 30100, Murcia, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fish Innate Immune System Group, Department of Cell Biology and Histology, Faculty of Biology, University of Murcia, 30100, Murcia, Spain","institution_ids":["https://openalex.org/I80180929"]},{"raw_affiliation_string":"Regional Campus of International Excellence \"Campus Mare Nostrum\", University of Murcia, 30100, Murcia, Spain","institution_ids":["https://openalex.org/I80180929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109035813","display_name":"Jos\u00e9 Meseguer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80180929","display_name":"Universidad de Murcia","ror":"https://ror.org/03p3aeb86","country_code":"ES","type":"education","lineage":["https://openalex.org/I80180929"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Meseguer","raw_affiliation_strings":["Fish Innate Immune System Group, Department of Cell Biology and Histology, Faculty of Biology, University of Murcia, 30100, Murcia, Spain","Regional Campus of International Excellence \"Campus Mare Nostrum\", University of Murcia, 30100, Murcia, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fish Innate Immune System Group, Department of Cell Biology and Histology, Faculty of Biology, University of Murcia, 30100, Murcia, Spain","institution_ids":["https://openalex.org/I80180929"]},{"raw_affiliation_string":"Regional Campus of International Excellence \"Campus Mare Nostrum\", University of Murcia, 30100, Murcia, Spain","institution_ids":["https://openalex.org/I80180929"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048150087","display_name":"Mar\u00eda \u00c1ngeles Esteban","orcid":"https://orcid.org/0000-0002-6264-1458","observed_orcids":["https://orcid.org/0000-0002-6264-1458"]},"institutions":[{"id":"https://openalex.org/I80180929","display_name":"Universidad de Murcia","ror":"https://ror.org/03p3aeb86","country_code":"ES","type":"education","lineage":["https://openalex.org/I80180929"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"M. \u00c1ngeles Esteban","raw_affiliation_strings":["Fish Innate Immune System Group, Department of Cell Biology and Histology, Faculty of Biology, University of Murcia, 30100, Murcia, Spain. aesteban@um.es","Regional Campus of International Excellence \"Campus Mare Nostrum\", University of Murcia, 30100, Murcia, Spain. aesteban@um.es","Regional Campus of International Excellence \"Campus Mare Nostrum\", University of Murcia, 30100, Murcia, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fish Innate Immune System Group, Department of Cell Biology and Histology, Faculty of Biology, University of Murcia, 30100, Murcia, Spain. aesteban@um.es","institution_ids":["https://openalex.org/I80180929"]},{"raw_affiliation_string":"Regional Campus of International Excellence \"Campus Mare Nostrum\", University of Murcia, 30100, Murcia, Spain. aesteban@um.es","institution_ids":["https://openalex.org/I80180929"]},{"raw_affiliation_string":"Regional Campus of International Excellence \"Campus Mare Nostrum\", University of Murcia, 30100, Murcia, Spain","institution_ids":["https://openalex.org/I80180929"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5048150087"],"corresponding_institution_ids":["https://openalex.org/I80180929"],"apc_list":{"value":2590,"currency":"USD","value_usd":2590},"apc_paid":null,"fwci":1.4293,"has_fulltext":false,"cited_by_count":147,"citation_normalized_percentile":{"value":0.79238555,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"38","issue":"6","first_page":"1729","last_page":"1739"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota","score":0.5410000085830688,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota","score":0.5410000085830688,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10450","display_name":"Aquaculture Nutrition and Growth","score":0.4580000042915344,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10152","display_name":"Animal Nutrition and Physiology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gilthead-seabream","display_name":"Sparus aurata","score":1.0},{"id":"https://openalex.org/keywords/nannochloropsis-gaditana","display_name":"Nannochloropsis gaditana","score":0.9380000233650208},{"id":"https://openalex.org/keywords/tetraselmis-chuii","display_name":"Tetraselmis chuii","score":0.9959999918937683},{"id":"https://openalex.org/keywords/phaeodactylum-tricornutum","display_name":"Phaeodactylum tricornutum","score":1.0},{"id":"https://openalex.org/keywords/fish-immunity","display_name":"fish immunity","score":0.7400000095367432},{"id":"https://openalex.org/keywords/immunostimulation","display_name":"immunostimulation","score":0.7739999890327454},{"id":"https://openalex.org/keywords/igm","display_name":"IgM","score":0.8999999761581421},{"id":"https://openalex.org/keywords/phagocytosis","display_name":"phagocytosis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/respiratory-burst","display_name":"respiratory burst","score":0.9959999918937683},{"id":"https://openalex.org/keywords/immune-related-gene-expression","display_name":"immune gene expression","score":0.8050000071525574},{"id":"https://openalex.org/keywords/beta-defensins","display_name":"beta-defensins","score":0.7850000262260437},{"id":"https://openalex.org/keywords/mhc-class-ii","display_name":"MHC class II","score":0.906000018119812},{"id":"https://openalex.org/keywords/csf1r","display_name":"CSF1R","score":0.9129999876022339},{"id":"https://openalex.org/keywords/head-kidney","display_name":"head kidney","score":0.8989999890327454},{"id":"https://openalex.org/keywords/intestine","display_name":"intestine","score":0.8259999752044678},{"id":"https://openalex.org/keywords/fish-feed-additives","display_name":"fish feed additives","score":0.7699999809265137}],"concepts":[{"id":"https://openalex.org/C2779064894","wikidata":"https://www.wikidata.org/wiki/Q7706731","display_name":"Tetraselmis","level":3,"score":0.892432451248169},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8517910838127136},{"id":"https://openalex.org/C2780655307","wikidata":"https://www.wikidata.org/wiki/Q4911639","display_name":"Phaeodactylum tricornutum","level":3,"score":0.7572537660598755},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.7153491973876953},{"id":"https://openalex.org/C99971728","wikidata":"https://www.wikidata.org/wiki/Q838181","display_name":"Respiratory burst","level":2,"score":0.495980829000473},{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.44261181354522705},{"id":"https://openalex.org/C160448771","wikidata":"https://www.wikidata.org/wiki/Q184726","display_name":"Phagocytosis","level":2,"score":0.42005935311317444},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.38321587443351746},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.33405035734176636},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3148348927497864},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.20545309782028198},{"id":"https://openalex.org/C559758991","wikidata":"https://www.wikidata.org/wiki/Q37868","display_name":"Algae","level":2,"score":0.1753649115562439}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000821","descriptor_name":"Animal Feed","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D000824","descriptor_name":"Animal Nutritional Physiological Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004032","descriptor_name":"Diet","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D007075","descriptor_name":"Immunoglobulin M","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007962","descriptor_name":"Leukocytes","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016897","descriptor_name":"Respiratory Burst","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021541","descriptor_name":"Sea Bream","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D058086","descriptor_name":"Microalgae","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D060888","descriptor_name":"Real-Time Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s10695-012-9670-9","doi":"https://doi.org/10.1007/s10695-012-9670-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10695-012-9670-9","pdf_url":null,"source":{"id":"https://openalex.org/S188633547","display_name":"Fish Physiology and Biochemistry","issn_l":"0920-1742","issn":["0920-1742","1573-5168"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fish Physiology and Biochemistry","raw_type":"journal-article"},{"id":"pmid:22678706","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22678706","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fish physiology and biochemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/14","display_name":"Life below water","score":1.0},{"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger","score":0.8409000039100647}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W178178881","https://openalex.org/W315063507","https://openalex.org/W1555267752","https://openalex.org/W1965357525","https://openalex.org/W1972983885","https://openalex.org/W1977046203","https://openalex.org/W1979763210","https://openalex.org/W1980210546","https://openalex.org/W1995872027","https://openalex.org/W2000797671","https://openalex.org/W2002624457","https://openalex.org/W2002626342","https://openalex.org/W2003428360","https://openalex.org/W2003990229","https://openalex.org/W2006139454","https://openalex.org/W2009499631","https://openalex.org/W2010397817","https://openalex.org/W2025149910","https://openalex.org/W2026009443","https://openalex.org/W2033909818","https://openalex.org/W2034898797","https://openalex.org/W2036465474","https://openalex.org/W2044335811","https://openalex.org/W2045599308","https://openalex.org/W2046141744","https://openalex.org/W2052380638","https://openalex.org/W2056064761","https://openalex.org/W2056332036","https://openalex.org/W2070333395","https://openalex.org/W2078384076","https://openalex.org/W2084895567","https://openalex.org/W2086987427","https://openalex.org/W2091018725","https://openalex.org/W2104452690","https://openalex.org/W2117908015","https://openalex.org/W2120187111","https://openalex.org/W2126362639","https://openalex.org/W2145008071","https://openalex.org/W2165189049","https://openalex.org/W2187292460","https://openalex.org/W2322754570"],"related_works":["https://openalex.org/W1986101932","https://openalex.org/W2004977741","https://openalex.org/W7131645513","https://openalex.org/W7038561451","https://openalex.org/W7087809307","https://openalex.org/W4416392520","https://openalex.org/W3128621441","https://openalex.org/W2980254187","https://openalex.org/W4318022772","https://openalex.org/W4313335106"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":10},{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":11},{"year":2022,"cited_by_count":23},{"year":2021,"cited_by_count":23},{"year":2020,"cited_by_count":19},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}