{"id":"https://openalex.org/W2048528776","doi":"https://doi.org/10.1007/s11920-004-0021-0","title":"Recent understanding in the mechanisms of addiction","display_name":"Recent understanding in the mechanisms of addiction","publication_year":2004,"publication_date":"2004-09-01","ids":{"openalex":"https://openalex.org/W2048528776","doi":"https://doi.org/10.1007/s11920-004-0021-0","mag":"2048528776","pmid":"https://pubmed.ncbi.nlm.nih.gov/15355757"},"language":"en","primary_location":{"id":"doi:10.1007/s11920-004-0021-0","doi":"https://doi.org/10.1007/s11920-004-0021-0","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11920-004-0021-0","pdf_url":null,"source":{"id":"https://openalex.org/S124600697","display_name":"Current Psychiatry Reports","issn_l":"1523-3812","issn":["1523-3812","1535-1645"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Psychiatry Reports","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078035590","display_name":"Peter W. Kalivas","orcid":"https://orcid.org/0000-0001-9487-0119","observed_orcids":["https://orcid.org/0000-0001-9487-0119"]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Peter W. Kalivas","raw_affiliation_strings":["Department of Neuroscience, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29464, USA. kalivasp@musc.edu","Department of Neuroscience, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29464, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29464, USA. kalivasp@musc.edu","institution_ids":["https://openalex.org/I153297377"]},{"raw_affiliation_string":"Department of Neuroscience, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29464, USA","institution_ids":["https://openalex.org/I153297377"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5078035590"],"corresponding_institution_ids":["https://openalex.org/I153297377"],"apc_list":{"value":4990,"currency":"USD","value_usd":4990},"apc_paid":null,"fwci":0.4451,"has_fulltext":false,"cited_by_count":64,"citation_normalized_percentile":{"value":0.36676218,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"6","issue":"5","first_page":"347","last_page":"351"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10043","display_name":"Substance Abuse Treatment and Outcomes","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/addiction-mechanisms","display_name":"addiction mechanisms","score":0.824999988079071},{"id":"https://openalex.org/keywords/drug-reward","display_name":"drug reward","score":0.6539999842643738},{"id":"https://openalex.org/keywords/dopaminergic-neurotransmission","display_name":"dopamine signaling","score":0.9539999961853027},{"id":"https://openalex.org/keywords/excitatory-neurotransmission","display_name":"excitatory neurotransmission","score":0.8080000281333923},{"id":"https://openalex.org/keywords/neuroplasticity","display_name":"neuroplasticity","score":0.8379999995231628},{"id":"https://openalex.org/keywords/relapse-vulnerability","display_name":"relapse vulnerability","score":0.9390000104904175},{"id":"https://openalex.org/keywords/craving","display_name":"craving","score":0.9570000171661377},{"id":"https://openalex.org/keywords/neuroimaging-of-addiction","display_name":"neuroimaging of addiction","score":0.6970000267028809},{"id":"https://openalex.org/keywords/therapeutic-target","display_name":"therapeutic target","score":0.7039999961853027}],"concepts":[{"id":"https://openalex.org/C48856860","wikidata":"https://www.wikidata.org/wiki/Q12029","display_name":"Addiction","level":2,"score":0.8294012546539307},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7539868950843811},{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.6944477558135986},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.5797717571258545},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.5440766215324402},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5397177338600159},{"id":"https://openalex.org/C2779541405","wikidata":"https://www.wikidata.org/wiki/Q498902","display_name":"Craving","level":3,"score":0.4847642779350281},{"id":"https://openalex.org/C95713431","wikidata":"https://www.wikidata.org/wiki/Q631425","display_name":"Vulnerability (computing)","level":2,"score":0.45035749673843384},{"id":"https://openalex.org/C3018481051","wikidata":"https://www.wikidata.org/wiki/Q3184856","display_name":"Drugs of abuse","level":3,"score":0.4334736764431},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34928733110427856},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.33062422275543213},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C38652104","wikidata":"https://www.wikidata.org/wiki/Q3510521","display_name":"Computer security","level":1,"score":0.0},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000222","descriptor_name":"Adaptation, Physiological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009435","descriptor_name":"Synaptic Transmission","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D009473","descriptor_name":"Neuronal Plasticity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018377","descriptor_name":"Neurotransmitter Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D018846","descriptor_name":"Excitatory Amino Acids","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D019966","descriptor_name":"Substance-Related Disorders","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/s11920-004-0021-0","doi":"https://doi.org/10.1007/s11920-004-0021-0","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11920-004-0021-0","pdf_url":null,"source":{"id":"https://openalex.org/S124600697","display_name":"Current Psychiatry Reports","issn_l":"1523-3812","issn":["1523-3812","1535-1645"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Psychiatry Reports","raw_type":"journal-article"},{"id":"pmid:15355757","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15355757","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current psychiatry reports","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W267545785","https://openalex.org/W1524081744","https://openalex.org/W1563427807","https://openalex.org/W1579135703","https://openalex.org/W1598659526","https://openalex.org/W1610317949","https://openalex.org/W1889428062","https://openalex.org/W1919544644","https://openalex.org/W1964374986","https://openalex.org/W1978847871","https://openalex.org/W1981727048","https://openalex.org/W1989416066","https://openalex.org/W1989953524","https://openalex.org/W1991007482","https://openalex.org/W2000825098","https://openalex.org/W2003729768","https://openalex.org/W2005435529","https://openalex.org/W2017277436","https://openalex.org/W2021782736","https://openalex.org/W2026010744","https://openalex.org/W2026795314","https://openalex.org/W2027127607","https://openalex.org/W2027184260","https://openalex.org/W2046536979","https://openalex.org/W2047884170","https://openalex.org/W2049796382","https://openalex.org/W2053135471","https://openalex.org/W2062345330","https://openalex.org/W2067317040","https://openalex.org/W2078339523","https://openalex.org/W2094284473","https://openalex.org/W2100579958","https://openalex.org/W2103057436","https://openalex.org/W2112824246","https://openalex.org/W2123946759","https://openalex.org/W2126440176","https://openalex.org/W2129688965","https://openalex.org/W2134624334","https://openalex.org/W2136550122","https://openalex.org/W2154850432","https://openalex.org/W2174764226","https://openalex.org/W2399045151","https://openalex.org/W2431986240","https://openalex.org/W4213265599"],"related_works":["https://openalex.org/W116630999","https://openalex.org/W1604137888","https://openalex.org/W2041018266","https://openalex.org/W1967842272","https://openalex.org/W2135159454","https://openalex.org/W1998033984","https://openalex.org/W2036768211","https://openalex.org/W1782902465","https://openalex.org/W4206898194","https://openalex.org/W2107413437"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}