{"id":"https://openalex.org/W2048168656","doi":"https://doi.org/10.1016/s0002-9394(14)74992-x","title":"Effect of the Herpes Simplex Virus Genome on the Response of Infection to Corticosteroids","display_name":"Effect of the Herpes Simplex Virus Genome on the Response of Infection to Corticosteroids","publication_year":1985,"publication_date":"1985-07-01","ids":{"openalex":"https://openalex.org/W2048168656","doi":"https://doi.org/10.1016/s0002-9394(14)74992-x","mag":"2048168656","pmid":"https://pubmed.ncbi.nlm.nih.gov/2990213"},"language":"en","primary_location":{"id":"doi:10.1016/s0002-9394(14)74992-x","doi":"https://doi.org/10.1016/s0002-9394(14)74992-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0002-9394(14)74992-x","pdf_url":null,"source":{"id":"https://openalex.org/S50016660","display_name":"American Journal of Ophthalmology","issn_l":"0002-9394","issn":["0002-9394","1879-1891"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Ophthalmology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109832842","display_name":"Herbert E. Kaufman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121820613","display_name":"Louisiana State University","ror":"https://ror.org/05ect4e57","country_code":"US","type":"education","lineage":["https://openalex.org/I121820613"]},{"id":"https://openalex.org/I75420490","display_name":"Louisiana State University Health Sciences Center New Orleans","ror":"https://ror.org/01qv8fp92","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121820613","https://openalex.org/I75420490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Herbert E. Kaufman","raw_affiliation_strings":["Lions Eye Research Laboratories, Louisiana State University Eye Center, Louisiana State University Medical Center School of Medicine, New Orleans, Louisiana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lions Eye Research Laboratories, Louisiana State University Eye Center, Louisiana State University Medical Center School of Medicine, New Orleans, Louisiana","institution_ids":["https://openalex.org/I121820613","https://openalex.org/I75420490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006558609","display_name":"Emily D. Varnell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121820613","display_name":"Louisiana State University","ror":"https://ror.org/05ect4e57","country_code":"US","type":"education","lineage":["https://openalex.org/I121820613"]},{"id":"https://openalex.org/I75420490","display_name":"Louisiana State University Health Sciences Center New Orleans","ror":"https://ror.org/01qv8fp92","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121820613","https://openalex.org/I75420490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emily D. Varnell","raw_affiliation_strings":["Lions Eye Research Laboratories, Louisiana State University Eye Center, Louisiana State University Medical Center School of Medicine, New Orleans, Louisiana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lions Eye Research Laboratories, Louisiana State University Eye Center, Louisiana State University Medical Center School of Medicine, New Orleans, Louisiana","institution_ids":["https://openalex.org/I121820613","https://openalex.org/I75420490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014544376","display_name":"Ysolina M. Centifanto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121820613","display_name":"Louisiana State University","ror":"https://ror.org/05ect4e57","country_code":"US","type":"education","lineage":["https://openalex.org/I121820613"]},{"id":"https://openalex.org/I75420490","display_name":"Louisiana State University Health Sciences Center New Orleans","ror":"https://ror.org/01qv8fp92","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121820613","https://openalex.org/I75420490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ysolina M. Centifanto","raw_affiliation_strings":["Lions Eye Research Laboratories, Louisiana State University Eye Center, Louisiana State University Medical Center School of Medicine, New Orleans, Louisiana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lions Eye Research Laboratories, Louisiana State University Eye Center, Louisiana State University Medical Center School of Medicine, New Orleans, Louisiana","institution_ids":["https://openalex.org/I121820613","https://openalex.org/I75420490"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110254923","display_name":"Grace E. Kissling","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121820613","display_name":"Louisiana State University","ror":"https://ror.org/05ect4e57","country_code":"US","type":"education","lineage":["https://openalex.org/I121820613"]},{"id":"https://openalex.org/I75420490","display_name":"Louisiana State University Health Sciences Center New Orleans","ror":"https://ror.org/01qv8fp92","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121820613","https://openalex.org/I75420490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Grace E. Kissling","raw_affiliation_strings":["Lions Eye Research Laboratories, Louisiana State University Eye Center, Louisiana State University Medical Center School of Medicine, New Orleans, Louisiana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lions Eye Research Laboratories, Louisiana State University Eye Center, Louisiana State University Medical Center School of Medicine, New Orleans, Louisiana","institution_ids":["https://openalex.org/I121820613","https://openalex.org/I75420490"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4300,"currency":"USD","value_usd":4300},"apc_paid":null,"fwci":2.4489,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.88907068,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"100","issue":"1","first_page":"114","last_page":"118"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11826","display_name":"Ocular Infections and Treatments","score":0.008500000461935997,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11194","display_name":"Ocular Diseases and Beh\u00e7et\u2019s Syndrome","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/herpes-simplex-virus-type-1","display_name":"herpes simplex virus type 1","score":0.996999979019165},{"id":"https://openalex.org/keywords/ocular-herpes","display_name":"ocular herpes","score":0.7720000147819519},{"id":"https://openalex.org/keywords/corticosteroid-therapy","display_name":"corticosteroid therapy","score":0.7649999856948853},{"id":"https://openalex.org/keywords/viral-genome","display_name":"viral genome","score":0.6299999952316284},{"id":"https://openalex.org/keywords/recombinant-virus-strains","display_name":"recombinant virus strains","score":0.8029999732971191},{"id":"https://openalex.org/keywords/disease-severity","display_name":"disease severity","score":0.6850000023841858},{"id":"https://openalex.org/keywords/viral-recurrence","display_name":"viral recurrence","score":0.5879999995231628},{"id":"https://openalex.org/keywords/viral-latency","display_name":"viral latency","score":0.7739999890327454},{"id":"https://openalex.org/keywords/corneal-infection","display_name":"corneal infection","score":0.7979999780654907}],"concepts":[{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.8100528717041016},{"id":"https://openalex.org/C2781196997","wikidata":"https://www.wikidata.org/wiki/Q655331","display_name":"Herpes simplex virus","level":3,"score":0.7082194685935974},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6571016907691956},{"id":"https://openalex.org/C32611913","wikidata":"https://www.wikidata.org/wiki/Q2166189","display_name":"Titer","level":3,"score":0.6299393177032471},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5737728476524353},{"id":"https://openalex.org/C2776409557","wikidata":"https://www.wikidata.org/wiki/Q149348","display_name":"Herpesviridae","level":4,"score":0.5464805364608765},{"id":"https://openalex.org/C180032290","wikidata":"https://www.wikidata.org/wiki/Q1664296","display_name":"Inoculation","level":2,"score":0.46470704674720764},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4583932161331177},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.43168550729751587},{"id":"https://openalex.org/C2776148792","wikidata":"https://www.wikidata.org/wiki/Q3041498","display_name":"Eye disease","level":2,"score":0.42703524231910706},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.40464070439338684},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.297770619392395},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.13360223174095154},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.12467071413993835}],"mesh":[{"descriptor_ui":"D000077555","descriptor_name":"Methylprednisolone Acetate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000305","descriptor_name":"Adrenal Cortex Hormones","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000305","descriptor_name":"Adrenal Cortex Hormones","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003907","descriptor_name":"Dexamethasone","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D003907","descriptor_name":"Dexamethasone","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D003907","descriptor_name":"Dexamethasone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005814","descriptor_name":"Genes, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007635","descriptor_name":"Keratitis, Dendritic","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D007635","descriptor_name":"Keratitis, Dendritic","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008775","descriptor_name":"Methylprednisolone","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D008775","descriptor_name":"Methylprednisolone","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D008775","descriptor_name":"Methylprednisolone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D009883","descriptor_name":"Ophthalmic Solutions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014276","descriptor_name":"Trigeminal Nerve","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D018139","descriptor_name":"Simplexvirus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018139","descriptor_name":"Simplexvirus","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0002-9394(14)74992-x","doi":"https://doi.org/10.1016/s0002-9394(14)74992-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0002-9394(14)74992-x","pdf_url":null,"source":{"id":"https://openalex.org/S50016660","display_name":"American Journal of Ophthalmology","issn_l":"0002-9394","issn":["0002-9394","1879-1891"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Ophthalmology","raw_type":"journal-article"},{"id":"pmid:2990213","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2990213","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of ophthalmology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1935544927","display_name":null,"funder_award_id":"EY02389","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G329114402","display_name":null,"funder_award_id":"EY-02377","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G4663327453","display_name":null,"funder_award_id":"EY02672","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"}],"funders":[{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W85678714","https://openalex.org/W1517483121","https://openalex.org/W1702322095","https://openalex.org/W1959454436","https://openalex.org/W2110109382","https://openalex.org/W2150415624","https://openalex.org/W2316638096"],"related_works":["https://openalex.org/W2104341578","https://openalex.org/W4313376342","https://openalex.org/W1488051142","https://openalex.org/W2140918066","https://openalex.org/W1976758171","https://openalex.org/W2087164101","https://openalex.org/W2103079381","https://openalex.org/W1987868585","https://openalex.org/W2118167284","https://openalex.org/W2110109382"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}