{"id":"https://openalex.org/W2047876231","doi":"https://doi.org/10.1021/ja076196l","title":"Fluorescently Labeled Cellulose Nanocrystals for Bioimaging Applications","display_name":"Fluorescently Labeled Cellulose Nanocrystals for Bioimaging Applications","publication_year":2007,"publication_date":"2007-10-19","ids":{"openalex":"https://openalex.org/W2047876231","doi":"https://doi.org/10.1021/ja076196l","mag":"2047876231","pmid":"https://pubmed.ncbi.nlm.nih.gov/17949004"},"language":"en","primary_location":{"id":"doi:10.1021/ja076196l","doi":"https://doi.org/10.1021/ja076196l","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ja076196l","pdf_url":null,"source":{"id":"https://openalex.org/S111155417","display_name":"Journal of the American Chemical Society","issn_l":"0002-7863","issn":["0002-7863","1520-5126","1943-2984"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Chemical Society","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2047876231"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110128026","display_name":"Shuping Dong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shuping Dong","raw_affiliation_strings":["Macromolecules and Interfaces Institute and Department of Wood Science and Forest Products, 230 Cheatham Hall, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061","Macromolecules and Interfaces Institute and Department of Wood Science and Forest Products, 230 Cheatham Hall, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Macromolecules and Interfaces Institute and Department of Wood Science and Forest Products, 230 Cheatham Hall, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061","institution_ids":["https://openalex.org/I859038795"]},{"raw_affiliation_string":"Macromolecules and Interfaces Institute and Department of Wood Science and Forest Products, 230 Cheatham Hall, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA","institution_ids":["https://openalex.org/I859038795"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003459488","display_name":"Maren Roman","orcid":"https://orcid.org/0000-0001-6622-8591","observed_orcids":["https://orcid.org/0000-0001-6622-8591"]},"institutions":[{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maren Roman","raw_affiliation_strings":["Macromolecules and Interfaces Institute and Department of Wood Science and Forest Products, 230 Cheatham Hall, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Macromolecules and Interfaces Institute and Department of Wood Science and Forest Products, 230 Cheatham Hall, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061","institution_ids":["https://openalex.org/I859038795"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I859038795"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":4.3221,"has_fulltext":false,"cited_by_count":505,"citation_normalized_percentile":{"value":0.95034522,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"129","issue":"45","first_page":"13810","last_page":"13811"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10610","display_name":"Advanced Cellulose Research Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10610","display_name":"Advanced Cellulose Research Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10869","display_name":"Polysaccharides and Plant Cell Walls","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11440","display_name":"Click Chemistry and Applications","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cellulose-nanocrystals","display_name":"cellulose nanocrystals","score":1.0},{"id":"https://openalex.org/keywords/fitc-labeling","display_name":"FITC labeling","score":0.7609999775886536},{"id":"https://openalex.org/keywords/bioimaging","display_name":"bioimaging","score":0.7850000262260437},{"id":"https://openalex.org/keywords/fluorescent-nanomaterials","display_name":"fluorescent nanomaterials","score":0.6079999804496765},{"id":"https://openalex.org/keywords/nanomedicine","display_name":"nanomedicine","score":0.8040000200271606}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8881827592849731},{"id":"https://openalex.org/C2779251873","wikidata":"https://www.wikidata.org/wiki/Q80294","display_name":"Cellulose","level":2,"score":0.8313915729522705},{"id":"https://openalex.org/C2777879272","wikidata":"https://www.wikidata.org/wiki/Q421888","display_name":"Ammonium hydroxide","level":2,"score":0.7705563306808472},{"id":"https://openalex.org/C175854130","wikidata":"https://www.wikidata.org/wiki/Q98276914","display_name":"Nanocrystal","level":2,"score":0.7438743710517883},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.5592905282974243},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.5310512185096741},{"id":"https://openalex.org/C2777019933","wikidata":"https://www.wikidata.org/wiki/Q853845","display_name":"Fluorescein isothiocyanate","level":3,"score":0.5256479978561401},{"id":"https://openalex.org/C2776572452","wikidata":"https://www.wikidata.org/wiki/Q416049","display_name":"Isothiocyanate","level":2,"score":0.5152378678321838},{"id":"https://openalex.org/C2187297","wikidata":"https://www.wikidata.org/wiki/Q910194","display_name":"Viscose","level":2,"score":0.44825950264930725},{"id":"https://openalex.org/C15083742","wikidata":"https://www.wikidata.org/wiki/Q261659","display_name":"Nanomedicine","level":3,"score":0.4246743321418762},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.4017886519432068},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.39034828543663025},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.3232075572013855},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.3210543394088745},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3110378384590149},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.29179906845092773},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.059048205614089966},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D002482","descriptor_name":"Cellulose","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D003952","descriptor_name":"Diagnostic Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D010316","descriptor_name":"Particle Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013194","descriptor_name":"Staining and Labeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013499","descriptor_name":"Surface Properties","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049329","descriptor_name":"Nanostructures","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1021/ja076196l","doi":"https://doi.org/10.1021/ja076196l","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ja076196l","pdf_url":null,"source":{"id":"https://openalex.org/S111155417","display_name":"Journal of the American Chemical Society","issn_l":"0002-7863","issn":["0002-7863","1520-5126","1943-2984"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Chemical Society","raw_type":"journal-article"},{"id":"pmid:17949004","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17949004","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Chemical Society","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W31352098","https://openalex.org/W1977479596","https://openalex.org/W1981904613","https://openalex.org/W1998033723","https://openalex.org/W2003845311","https://openalex.org/W2013706088","https://openalex.org/W2073161311","https://openalex.org/W2083829675","https://openalex.org/W2098358122","https://openalex.org/W2142575536","https://openalex.org/W4210466072"],"related_works":["https://openalex.org/W2040451030","https://openalex.org/W1991751758","https://openalex.org/W4225275683","https://openalex.org/W2993283826","https://openalex.org/W7133789796","https://openalex.org/W3182069150","https://openalex.org/W1982641624","https://openalex.org/W4224229948","https://openalex.org/W2331011464","https://openalex.org/W2497697416"],"abstract_inverted_index":{"Cellulose":[0],"nanocrystals":[1,24,66],"are":[2],"promising":[3],"candidates":[4],"for":[5],"applications":[6],"in":[7,16,17,20],"nanomedicine.":[8],"To":[9],"enable":[10],"the":[11,38,43,55,63,92],"use":[12],"of":[13,37,42,51,62,75,78],"fluorescence":[14],"techniques":[15],"vitro":[18],"and":[19,49],"vivo":[21],"studies,":[22],"cellulose":[23,65],"were":[25],"labeled":[26,64],"with":[27,46],"fluorescein-5\u2018-isothiocyanate":[28],"(FITC)":[29],"via":[30],"a":[31],"three-step":[32],"reaction,":[33],"involving":[34],"epoxy":[35,44],"activation":[36],"nanocrystal":[39],"surface,":[40],"opening":[41],"rings":[45],"ammonium":[47],"hydroxide,":[48],"coupling":[50],"FITC":[52,60,73,83],"molecules":[53],"to":[54,81],"primary":[56],"amino":[57],"groups.":[58],"The":[59],"content":[61,74],"was":[67,89],"determined":[68],"by":[69],"UV/vis":[70],"spectroscopy.":[71],"A":[72],"0.03":[76],"mmol/g":[77],"cellulose,":[79],"equivalent":[80],"5":[82],"moieties":[84],"per":[85],"1000":[86],"anhydroglucose":[87],"units,":[88],"obtained":[90],"using":[91],"described":[93],"method.":[94]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":21},{"year":2023,"cited_by_count":19},{"year":2022,"cited_by_count":14},{"year":2021,"cited_by_count":33},{"year":2020,"cited_by_count":37},{"year":2019,"cited_by_count":46},{"year":2018,"cited_by_count":43},{"year":2017,"cited_by_count":38},{"year":2016,"cited_by_count":39},{"year":2015,"cited_by_count":33},{"year":2014,"cited_by_count":52},{"year":2013,"cited_by_count":28},{"year":2012,"cited_by_count":29}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}