{"id":"https://openalex.org/W2047745366","doi":"https://doi.org/10.2174/156652409787581547","title":"The Association of Connective Tissue Disorders with Cervical Artery Dissections","display_name":"The Association of Connective Tissue Disorders with Cervical Artery Dissections","publication_year":2009,"publication_date":"2009-03-01","ids":{"openalex":"https://openalex.org/W2047745366","doi":"https://doi.org/10.2174/156652409787581547","mag":"2047745366","pmid":"https://pubmed.ncbi.nlm.nih.gov/19275629"},"language":"en","primary_location":{"id":"doi:10.2174/156652409787581547","doi":"https://doi.org/10.2174/156652409787581547","is_oa":false,"landing_page_url":"https://doi.org/10.2174/156652409787581547","pdf_url":null,"source":{"id":"https://openalex.org/S50220609","display_name":"Current Molecular Medicine","issn_l":"1566-5240","issn":["1566-5240","1875-5666"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320079","host_organization_name":"Bentham Science Publishers","host_organization_lineage":["https://openalex.org/P4310320079"],"host_organization_lineage_names":["Bentham Science Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Molecular Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048264370","display_name":"Caspar Grond\u2010Ginsbach","orcid":"https://orcid.org/0000-0002-6882-3148","observed_orcids":["https://orcid.org/0000-0002-6882-3148"]},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Caspar Grond-Ginsbach","raw_affiliation_strings":["Department of Neurology, University of Heidelberg, 69120 Heidelberg, Germany. caspar_grond-ginsbach@med.uni-heidelberg.de","Department of Neurology, University of Heidelberg, 69120 Heidelberg, Germany,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University of Heidelberg, 69120 Heidelberg, Germany. caspar_grond-ginsbach@med.uni-heidelberg.de","institution_ids":["https://openalex.org/I223822909"]},{"raw_affiliation_string":"Department of Neurology, University of Heidelberg, 69120 Heidelberg, Germany,","institution_ids":["https://openalex.org/I223822909"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077569991","display_name":"St\u00e9phanie Debette","orcid":"https://orcid.org/0000-0001-8675-7968","observed_orcids":["https://orcid.org/0000-0001-8675-7968"]},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Stephanie Debette","raw_affiliation_strings":["Department of Neurology, University of Heidelberg, 69120 Heidelberg, Germany.,Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University of Heidelberg, 69120 Heidelberg, Germany.,Germany","institution_ids":["https://openalex.org/I223822909"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5077569991"],"corresponding_institution_ids":["https://openalex.org/I223822909"],"apc_list":null,"apc_paid":null,"fwci":3.1737,"has_fulltext":false,"cited_by_count":78,"citation_normalized_percentile":{"value":0.92317908,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"9","issue":"2","first_page":"210","last_page":"214"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10816","display_name":"Cerebrovascular and Carotid Artery Diseases","score":0.5503000020980835,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10816","display_name":"Cerebrovascular and Carotid Artery Diseases","score":0.5503000020980835,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11310","display_name":"Connective tissue disorders research","score":0.29829999804496765,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13648","display_name":"Cerebrovascular and genetic disorders","score":0.0421999990940094,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cervical-artery-dissection","display_name":"cervical artery dissection","score":0.9150000214576721},{"id":"https://openalex.org/keywords/connective-tissue-diseases","display_name":"connective tissue diseases","score":0.8629999756813049},{"id":"https://openalex.org/keywords/ehlers-danlos-syndrome","display_name":"Ehlers-Danlos syndrome","score":0.9330000281333923},{"id":"https://openalex.org/keywords/marfan-syndrome","display_name":"Marfan syndrome","score":1.0},{"id":"https://openalex.org/keywords/osteogenesis-imperfecta","display_name":"osteogenesis imperfecta","score":0.9990000128746033},{"id":"https://openalex.org/keywords/skin-biopsy","display_name":"skin biopsy","score":0.6600000262260437},{"id":"https://openalex.org/keywords/heritable-connective-tissue-disorders","display_name":"hereditary connective tissue disorders","score":0.7870000004768372}],"concepts":[{"id":"https://openalex.org/C518705261","wikidata":"https://www.wikidata.org/wiki/Q25615","display_name":"Connective tissue","level":2,"score":0.8865234851837158},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.754230260848999},{"id":"https://openalex.org/C2910348082","wikidata":"https://www.wikidata.org/wiki/Q19919956","display_name":"Cervical Artery","level":3,"score":0.6969242691993713},{"id":"https://openalex.org/C2780561598","wikidata":"https://www.wikidata.org/wiki/Q208562","display_name":"Marfan syndrome","level":2,"score":0.6617220044136047},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.6169939637184143},{"id":"https://openalex.org/C2776670291","wikidata":"https://www.wikidata.org/wiki/Q1779300","display_name":"Connective tissue disease","level":4,"score":0.5741791129112244},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5066273808479309},{"id":"https://openalex.org/C2777668750","wikidata":"https://www.wikidata.org/wiki/Q749409","display_name":"Osteogenesis imperfecta","level":2,"score":0.5062588453292847},{"id":"https://openalex.org/C2780247198","wikidata":"https://www.wikidata.org/wiki/Q633403","display_name":"Weakness","level":2,"score":0.4285944402217865},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3451346158981323},{"id":"https://openalex.org/C2775862295","wikidata":"https://www.wikidata.org/wiki/Q2660911","display_name":"Dissection (medical)","level":2,"score":0.324715793132782},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.2748411297798157},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.19251134991645813},{"id":"https://openalex.org/C2779075594","wikidata":"https://www.wikidata.org/wiki/Q8084905","display_name":"Autoimmune disease","level":3,"score":0.0777789056301117}],"mesh":[{"descriptor_ui":"D000784","descriptor_name":"Aortic Dissection","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D000784","descriptor_name":"Aortic Dissection","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001808","descriptor_name":"Blood Vessels","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D002574","descriptor_name":"Cervical Vertebrae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003240","descriptor_name":"Connective Tissue Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003240","descriptor_name":"Connective Tissue Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D004535","descriptor_name":"Ehlers-Danlos Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D004535","descriptor_name":"Ehlers-Danlos Syndrome","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008382","descriptor_name":"Marfan Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D008382","descriptor_name":"Marfan Syndrome","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010013","descriptor_name":"Osteogenesis Imperfecta","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D010013","descriptor_name":"Osteogenesis Imperfecta","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.2174/156652409787581547","doi":"https://doi.org/10.2174/156652409787581547","is_oa":false,"landing_page_url":"https://doi.org/10.2174/156652409787581547","pdf_url":null,"source":{"id":"https://openalex.org/S50220609","display_name":"Current Molecular Medicine","issn_l":"1566-5240","issn":["1566-5240","1875-5666"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320079","host_organization_name":"Bentham Science Publishers","host_organization_lineage":["https://openalex.org/P4310320079"],"host_organization_lineage_names":["Bentham Science Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Molecular Medicine","raw_type":"journal-article"},{"id":"pmid:19275629","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19275629","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current molecular medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":1,"referenced_works":["https://openalex.org/W1508890097"],"related_works":["https://openalex.org/W1537388056","https://openalex.org/W1988102686","https://openalex.org/W2047547069","https://openalex.org/W2018205744","https://openalex.org/W2023435138","https://openalex.org/W2025179972","https://openalex.org/W4387537640","https://openalex.org/W2081912327","https://openalex.org/W4384009959","https://openalex.org/W2158771901"],"abstract_inverted_index":{"A":[0],"predisposing":[1],"weakness":[2],"of":[3,43,52,86,94,99,106],"the":[4,50,91,104],"vessel":[5],"wall":[6],"has":[7],"been":[8],"assumed":[9],"in":[10,49,103],"patients":[11,22,65],"with":[12,23],"spontaneous":[13],"cervical":[14],"artery":[15],"dissections":[16],"(sCAD).":[17],"Skin":[18],"biopsies":[19],"from":[20],"many":[21],"sCAD":[24],"show":[25],"mild":[26],"connective":[27,44,71,100],"tissue":[28,45,72,101],"alterations.":[29],"However,":[30],"their":[31],"assessment":[32],"depends":[33],"on":[34],"an":[35],"invasive":[36],"and":[37],"highly":[38],"specialized":[39],"technique.":[40],"Clinical":[41],"signs":[42],"disease":[46],"are":[47,66],"absent":[48],"majority":[51],"CAD":[53,64],"patients.":[54],"In":[55,82],"this":[56,87],"review":[57,88],"we":[58,89],"document":[59],"that":[60],"only":[61],"very":[62],"few":[63],"affected":[67],"by":[68],"known":[69],"inherited":[70],"disorders":[73,102],"like":[74],"Ehlers-Danlos":[75],"syndrome,":[76],"Marfan":[77],"syndrome":[78],"or":[79,96],"Osteogenesis":[80],"Imperfecta.":[81],"a":[83],"second":[84],"part":[85],"discuss":[90],"possible":[92],"role":[93],"unrecognized":[95],"unknown":[97],"forms":[98],"etiology":[105],"CAD.":[107]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}