{"id":"https://openalex.org/W2047424751","doi":"https://doi.org/10.2169/internalmedicine.54.3624","title":"Intravascular Synovial Sarcoma of the Pulmonary Artery with Massive Pleural Effusion: Report of a Case with a Favorable Response to Ifosfamide Chemotherapy and Palliative Radiation Therapy","display_name":"Intravascular Synovial Sarcoma of the Pulmonary Artery with Massive Pleural Effusion: Report of a Case with a Favorable Response to Ifosfamide Chemotherapy and Palliative Radiation Therapy","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2047424751","doi":"https://doi.org/10.2169/internalmedicine.54.3624","mag":"2047424751","pmid":"https://pubmed.ncbi.nlm.nih.gov/25948355"},"language":"en","primary_location":{"id":"doi:10.2169/internalmedicine.54.3624","doi":"https://doi.org/10.2169/internalmedicine.54.3624","is_oa":true,"landing_page_url":"https://doi.org/10.2169/internalmedicine.54.3624","pdf_url":"https://www.jstage.jst.go.jp/article/internalmedicine/54/9/54_54.3624/_pdf","source":{"id":"https://openalex.org/S154471048","display_name":"Internal Medicine","issn_l":"0918-2918","issn":["0918-2918","1349-7235"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313351","host_organization_name":"The Japanese Society of Internal Medicine","host_organization_lineage":["https://openalex.org/P4310313351"],"host_organization_lineage_names":["The Japanese Society of Internal Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Internal Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.jstage.jst.go.jp/article/internalmedicine/54/9/54_54.3624/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008954860","display_name":"Toshiya Maekura","orcid":"https://orcid.org/0000-0003-0344-5227","observed_orcids":["https://orcid.org/0000-0003-0344-5227"]},"institutions":[{"id":"https://openalex.org/I4210160708","display_name":"NHO Kinki Chuo Chest Medical Center","ror":"https://ror.org/05jp74k96","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210137409","https://openalex.org/I4210160708"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshiya Maekura","raw_affiliation_strings":["Department of Internal Medicine, National Hospital Organization Kinki-chuo Chest Medical Center, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, National Hospital Organization Kinki-chuo Chest Medical Center, Japan","institution_ids":["https://openalex.org/I4210160708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012798813","display_name":"Shigeki Shimizu","orcid":"https://orcid.org/0000-0001-9675-2589","observed_orcids":["https://orcid.org/0000-0001-9675-2589"]},"institutions":[{"id":"https://openalex.org/I4210160708","display_name":"NHO Kinki Chuo Chest Medical Center","ror":"https://ror.org/05jp74k96","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210137409","https://openalex.org/I4210160708"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shigeki Shimizu","raw_affiliation_strings":["Department of Laboratory Medicine and Pathology, National Hospital Organization Kinki-chuo Chest Medical Center, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology, National Hospital Organization Kinki-chuo Chest Medical Center, Japan","institution_ids":["https://openalex.org/I4210160708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044361715","display_name":"Tomoya Kawaguchi","orcid":"https://orcid.org/0000-0002-7600-4847","observed_orcids":["https://orcid.org/0000-0002-7600-4847"]},"institutions":[{"id":"https://openalex.org/I317356780","display_name":"Osaka City University","ror":"https://ror.org/02skfsw40","country_code":"JP","type":"education","lineage":["https://openalex.org/I317356780","https://openalex.org/I4387152983"]},{"id":"https://openalex.org/I4210160708","display_name":"NHO Kinki Chuo Chest Medical Center","ror":"https://ror.org/05jp74k96","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210137409","https://openalex.org/I4210160708"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomoya Kawaguchi","raw_affiliation_strings":["Department of Internal Medicine, National Hospital Organization Kinki-chuo Chest Medical Center, Japan","Department of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, National Hospital Organization Kinki-chuo Chest Medical Center, Japan","institution_ids":["https://openalex.org/I4210160708"]},{"raw_affiliation_string":"Department of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Japan","institution_ids":["https://openalex.org/I317356780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101457844","display_name":"Masahiro Morimoto","orcid":"https://orcid.org/0000-0001-6646-7488","observed_orcids":["https://orcid.org/0000-0001-6646-7488"]},"institutions":[{"id":"https://openalex.org/I4210160708","display_name":"NHO Kinki Chuo Chest Medical Center","ror":"https://ror.org/05jp74k96","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210137409","https://openalex.org/I4210160708"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masahiro Morimoto","raw_affiliation_strings":["Department of Radiation Oncology, National Hospital Organization Kinki-chuo Chest Medical Center, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, National Hospital Organization Kinki-chuo Chest Medical Center, Japan","institution_ids":["https://openalex.org/I4210160708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001525646","display_name":"Tomohisa Okuma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I317356780","display_name":"Osaka City University","ror":"https://ror.org/02skfsw40","country_code":"JP","type":"education","lineage":["https://openalex.org/I317356780","https://openalex.org/I4387152983"]},{"id":"https://openalex.org/I4210160708","display_name":"NHO Kinki Chuo Chest Medical Center","ror":"https://ror.org/05jp74k96","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210137409","https://openalex.org/I4210160708"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomohisa Okuma","raw_affiliation_strings":["Department of Radiology, Graduate School of Medicine, Osaka City University, Japan","Department of Radiology, National Hospital Organization Kinki-chuo Chest Medical Center, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Graduate School of Medicine, Osaka City University, Japan","institution_ids":["https://openalex.org/I317356780"]},{"raw_affiliation_string":"Department of Radiology, National Hospital Organization Kinki-chuo Chest Medical Center, Japan","institution_ids":["https://openalex.org/I4210160708"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hideo Matsui","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160708","display_name":"NHO Kinki Chuo Chest Medical Center","ror":"https://ror.org/05jp74k96","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210137409","https://openalex.org/I4210160708"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hideo Matsui","raw_affiliation_strings":["Division of Cardiology, National Hospital Organization Kinki-chuo Chest Medical Center, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, National Hospital Organization Kinki-chuo Chest Medical Center, Japan","institution_ids":["https://openalex.org/I4210160708"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066357817","display_name":"Shinji Atagi","orcid":"https://orcid.org/0000-0003-1876-7069","observed_orcids":["https://orcid.org/0000-0003-1876-7069"]},"institutions":[{"id":"https://openalex.org/I4210160708","display_name":"NHO Kinki Chuo Chest Medical Center","ror":"https://ror.org/05jp74k96","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210137409","https://openalex.org/I4210160708"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinji Atagi","raw_affiliation_strings":["Department of Internal Medicine, National Hospital Organization Kinki-chuo Chest Medical Center, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, National Hospital Organization Kinki-chuo Chest Medical Center, Japan","institution_ids":["https://openalex.org/I4210160708"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":95},"biblio":{"volume":"54","issue":"9","first_page":"1095","last_page":"1098"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.9434000253677368,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.9434000253677368,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11638","display_name":"Cardiac tumors and thrombi","score":0.05260000005364418,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12278","display_name":"Vascular Tumors and Angiosarcomas","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/synovial-sarcoma","display_name":"synovial sarcoma","score":0.953000009059906},{"id":"https://openalex.org/keywords/pulmonary-artery","display_name":"pulmonary artery","score":0.8820000290870667},{"id":"https://openalex.org/keywords/pleural-effusion","display_name":"pleural effusion","score":0.9860000014305115},{"id":"https://openalex.org/keywords/syt-ssx-fusion-gene","display_name":"SYT-SSX fusion gene","score":0.8479999899864197},{"id":"https://openalex.org/keywords/palliative-radiotherapy","display_name":"palliative radiotherapy","score":0.8849999904632568},{"id":"https://openalex.org/keywords/unresectable-sarcoma","display_name":"unresectable sarcoma","score":0.7400000095367432},{"id":"https://openalex.org/keywords/spindle-cell-proliferation","display_name":"spindle cell proliferation","score":0.7419999837875366}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9469829797744751},{"id":"https://openalex.org/C2777506904","wikidata":"https://www.wikidata.org/wiki/Q418560","display_name":"Ifosfamide","level":4,"score":0.6954293251037598},{"id":"https://openalex.org/C2780940725","wikidata":"https://www.wikidata.org/wiki/Q206280","display_name":"Pulmonary artery","level":2,"score":0.5845615863800049},{"id":"https://openalex.org/C2779634585","wikidata":"https://www.wikidata.org/wiki/Q1334541","display_name":"Pleural effusion","level":2,"score":0.5794571042060852},{"id":"https://openalex.org/C2776910622","wikidata":"https://www.wikidata.org/wiki/Q2619315","display_name":"Synovial sarcoma","level":3,"score":0.5638588070869446},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.5618154406547546},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.47973954677581787},{"id":"https://openalex.org/C2778256501","wikidata":"https://www.wikidata.org/wiki/Q223911","display_name":"Sarcoma","level":2,"score":0.430630624294281},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.41879206895828247},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3290354013442993},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2644878029823303},{"id":"https://openalex.org/C2778119113","wikidata":"https://www.wikidata.org/wiki/Q418817","display_name":"Etoposide","level":3,"score":0.07964611053466797}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007069","descriptor_name":"Ifosfamide","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D010996","descriptor_name":"Pleural Effusion","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D010996","descriptor_name":"Pleural Effusion","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D011651","descriptor_name":"Pulmonary Artery","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D013584","descriptor_name":"Sarcoma, Synovial","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D013584","descriptor_name":"Sarcoma, Synovial","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D013584","descriptor_name":"Sarcoma, Synovial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013584","descriptor_name":"Sarcoma, Synovial","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D014178","descriptor_name":"Translocation, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015514","descriptor_name":"Oncogene Proteins, Fusion","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018906","descriptor_name":"Antineoplastic Agents, Alkylating","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D019043","descriptor_name":"Vascular Neoplasms","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D019043","descriptor_name":"Vascular Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D019043","descriptor_name":"Vascular Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019043","descriptor_name":"Vascular Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.2169/internalmedicine.54.3624","doi":"https://doi.org/10.2169/internalmedicine.54.3624","is_oa":true,"landing_page_url":"https://doi.org/10.2169/internalmedicine.54.3624","pdf_url":"https://www.jstage.jst.go.jp/article/internalmedicine/54/9/54_54.3624/_pdf","source":{"id":"https://openalex.org/S154471048","display_name":"Internal Medicine","issn_l":"0918-2918","issn":["0918-2918","1349-7235"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313351","host_organization_name":"The Japanese Society of Internal Medicine","host_organization_lineage":["https://openalex.org/P4310313351"],"host_organization_lineage_names":["The Japanese Society of Internal Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Internal Medicine","raw_type":"journal-article"},{"id":"pmid:25948355","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25948355","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Internal medicine (Tokyo, Japan)","raw_type":"Case Reports"}],"best_oa_location":{"id":"doi:10.2169/internalmedicine.54.3624","doi":"https://doi.org/10.2169/internalmedicine.54.3624","is_oa":true,"landing_page_url":"https://doi.org/10.2169/internalmedicine.54.3624","pdf_url":"https://www.jstage.jst.go.jp/article/internalmedicine/54/9/54_54.3624/_pdf","source":{"id":"https://openalex.org/S154471048","display_name":"Internal Medicine","issn_l":"0918-2918","issn":["0918-2918","1349-7235"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313351","host_organization_name":"The Japanese Society of Internal Medicine","host_organization_lineage":["https://openalex.org/P4310313351"],"host_organization_lineage_names":["The Japanese Society of Internal Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Internal Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[{"id":"https://openalex.org/G617828139","display_name":"CT-guided radiofrequency ablation with chemotherapy in a rabbit VX2 lung tumor model","funder_award_id":"25461887","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2047424751.pdf","grobid_xml":"https://content.openalex.org/works/W2047424751.grobid-xml"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W1975011890","https://openalex.org/W1981232942","https://openalex.org/W2015710137","https://openalex.org/W2017792308","https://openalex.org/W2040140652","https://openalex.org/W2040812093","https://openalex.org/W2044728980","https://openalex.org/W2056948967","https://openalex.org/W2077274936","https://openalex.org/W2099990434","https://openalex.org/W2153072731","https://openalex.org/W2154489873","https://openalex.org/W2313795942"],"related_works":["https://openalex.org/W2141001525","https://openalex.org/W2606599144","https://openalex.org/W97783736","https://openalex.org/W7098990464","https://openalex.org/W1767048375","https://openalex.org/W2343432982","https://openalex.org/W4395693500","https://openalex.org/W4362704084","https://openalex.org/W2040094591","https://openalex.org/W2093809931"],"abstract_inverted_index":{"Synovial":[0],"sarcoma":[1],"(SS)":[2],"commonly":[3],"arises":[4],"in":[5,76,83,103],"the":[6,38,48,78,81,84,98,104],"para-articular":[7],"soft":[8],"tissue;":[9],"however,":[10],"very":[11],"few":[12],"cases":[13],"of":[14,27,37,80,100],"intravascular":[15],"SS":[16,30,102],"have":[17],"so":[18],"far":[19],"been":[20],"reported.":[21],"We":[22],"herein":[23],"describe":[24],"a":[25],"case":[26],"pulmonary":[28,85,105],"artery":[29,86],"with":[31,67],"massive":[32],"pleural":[33,39,88],"effusion.":[34],"A":[35],"biopsy":[36],"lesions":[40],"showed":[41],"uniform":[42],"short":[43],"spindle":[44],"cell":[45],"proliferation,":[46],"while":[47],"SYT-SSX":[49],"fusion":[50],"gene,":[51],"which":[52],"is":[53],"preceded":[54],"by":[55],"chromosomal":[56],"translocation":[57],"t(X;18)(p11;q11),":[58],"was":[59,74],"detected":[60],"using":[61],"reverse":[62],"transcription-polymerase":[63],"chain":[64],"reaction.":[65],"Treatment":[66],"ifosfamide":[68],"chemotherapy":[69],"and":[70,87],"palliative":[71],"radiation":[72],"therapy":[73],"effective":[75],"reducing":[77],"growth":[79],"tumor":[82],"lesions,":[89],"indicating":[90],"that":[91],"this":[92],"regimen":[93],"may":[94],"be":[95],"useful":[96],"for":[97],"treatment":[99],"unresectable":[101],"artery.":[106]},"counts_by_year":[{"year":2020,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}