{"id":"https://openalex.org/W2046998293","doi":"https://doi.org/10.1111/j.1365-2249.1995.tb05526.x","title":"Effects of anti-CD3 monoclonal antibodies on functional activity of lymphocytes: studiesin vivoandin vitro","display_name":"Effects of anti-CD3 monoclonal antibodies on functional activity of lymphocytes: studiesin vivoandin vitro","publication_year":1995,"publication_date":"1995-02-01","ids":{"openalex":"https://openalex.org/W2046998293","doi":"https://doi.org/10.1111/j.1365-2249.1995.tb05526.x","mag":"2046998293","pmid":"https://pubmed.ncbi.nlm.nih.gov/7851005","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1534302"},"language":"en","primary_location":{"id":"doi:10.1111/j.1365-2249.1995.tb05526.x","doi":"https://doi.org/10.1111/j.1365-2249.1995.tb05526.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1365-2249.1995.tb05526.x","pdf_url":null,"source":{"id":"https://openalex.org/S11896317","display_name":"Clinical & Experimental Immunology","issn_l":"0009-9104","issn":["0009-9104","1365-2249"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Experimental Immunology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1534302","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111644135","display_name":"Karine J. Parlevliet","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802928900","display_name":"Amsterdam UMC Location University of Amsterdam","ror":"https://ror.org/03t4gr691","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802928900","https://openalex.org/I4210151833"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"KJ Parlevliet","raw_affiliation_strings":["Renal Transplant Unit, Depaprtment of Internal Medicine, Academic Medical Centre, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Renal Transplant Unit, Depaprtment of Internal Medicine, Academic Medical Centre, The Netherlands","institution_ids":["https://openalex.org/I2802928900"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010979808","display_name":"Martine E.D. Chamuleau","orcid":"https://orcid.org/0000-0002-0123-9182","observed_orcids":["https://orcid.org/0000-0002-0123-9182"]},"institutions":[{"id":"https://openalex.org/I2802928900","display_name":"Amsterdam UMC Location University of Amsterdam","ror":"https://ror.org/03t4gr691","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802928900","https://openalex.org/I4210151833"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"M E D Chamuleau","raw_affiliation_strings":["Clinical Immunology and Laboratory Unit, Depaprtment of Internal Medicine, Academic Medical Centre, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Immunology and Laboratory Unit, Depaprtment of Internal Medicine, Academic Medical Centre, The Netherlands","institution_ids":["https://openalex.org/I2802928900"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112188452","display_name":"Sandro L. Yong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802928900","display_name":"Amsterdam UMC Location University of Amsterdam","ror":"https://ror.org/03t4gr691","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802928900","https://openalex.org/I4210151833"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"S-L Yong","raw_affiliation_strings":["Clinical Immunology and Laboratory Unit, Depaprtment of Internal Medicine, Academic Medical Centre, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Immunology and Laboratory Unit, Depaprtment of Internal Medicine, Academic Medical Centre, The Netherlands","institution_ids":["https://openalex.org/I2802928900"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083290804","display_name":"Maarten H. M. Raasveld","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802928900","display_name":"Amsterdam UMC Location University of Amsterdam","ror":"https://ror.org/03t4gr691","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802928900","https://openalex.org/I4210151833"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"M H M Raasveld","raw_affiliation_strings":["Clinical Immunology and Laboratory Unit, Depaprtment of Internal Medicine, Academic Medical Centre, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Immunology and Laboratory Unit, Depaprtment of Internal Medicine, Academic Medical Centre, The Netherlands","institution_ids":["https://openalex.org/I2802928900"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090883710","display_name":"Ineke J. M. ten Berge","orcid":"https://orcid.org/0000-0001-8535-2766","observed_orcids":["https://orcid.org/0000-0001-8535-2766"]},"institutions":[{"id":"https://openalex.org/I2802928900","display_name":"Amsterdam UMC Location University of Amsterdam","ror":"https://ror.org/03t4gr691","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802928900","https://openalex.org/I4210151833"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"I J M Ten Berge","raw_affiliation_strings":["Renal Transplant Unit, Depaprtment of Internal Medicine, Academic Medical Centre, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Renal Transplant Unit, Depaprtment of Internal Medicine, Academic Medical Centre, The Netherlands","institution_ids":["https://openalex.org/I2802928900"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109155294","display_name":"Peter T. A. Schellekens","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802928900","display_name":"Amsterdam UMC Location University of Amsterdam","ror":"https://ror.org/03t4gr691","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802928900","https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I887064364","display_name":"University of Amsterdam","ror":"https://ror.org/04dkp9463","country_code":"NL","type":"education","lineage":["https://openalex.org/I887064364"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"P TH A Schellekens","raw_affiliation_strings":["Clinical Immunology and Laboratory Unit, Depaprtment of Internal Medicine, Academic Medical Centre, The Netherlands","Laboratory of Experimental and Clinical Immunology, Central laboratory of the Netherlands Red Cross Bloodtransfusion Service, University of Amsterdam, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Immunology and Laboratory Unit, Depaprtment of Internal Medicine, Academic Medical Centre, The Netherlands","institution_ids":["https://openalex.org/I2802928900"]},{"raw_affiliation_string":"Laboratory of Experimental and Clinical Immunology, Central laboratory of the Netherlands Red Cross Bloodtransfusion Service, University of Amsterdam, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I887064364"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5109155294"],"corresponding_institution_ids":["https://openalex.org/I2802928900","https://openalex.org/I887064364"],"apc_list":{"value":2894,"currency":"GBP","value_usd":3816},"apc_paid":null,"fwci":0.2649,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.51342664,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"99","issue":"2","first_page":"155","last_page":"159"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.3783999979496002,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.3783999979496002,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.3386000096797943,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.26510000228881836,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/anti-cd3-monoclonal-antibody","display_name":"anti-CD3 monoclonal antibody","score":0.9980000257492065},{"id":"https://openalex.org/keywords/okt3","display_name":"OKT3","score":0.9900000095367432},{"id":"https://openalex.org/keywords/kidney-transplantation","display_name":"kidney transplantation","score":0.6290000081062317},{"id":"https://openalex.org/keywords/induction-therapy","display_name":"induction therapy","score":0.7440000176429749},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.921999990940094},{"id":"https://openalex.org/keywords/lymphocyte-function","display_name":"lymphocyte function","score":0.8489999771118164},{"id":"https://openalex.org/keywords/phytohemagglutinin-response","display_name":"phytohemagglutinin response","score":0.9909999966621399},{"id":"https://openalex.org/keywords/t-cell-receptor-complex","display_name":"T cell receptor complex","score":0.7020000219345093},{"id":"https://openalex.org/keywords/cd3","display_name":"CD3","score":0.7620000243186951},{"id":"https://openalex.org/keywords/fc-receptors","display_name":"Fc receptors","score":0.7620000243186951},{"id":"https://openalex.org/keywords/monocytes","display_name":"monocytes","score":0.8140000104904175}],"concepts":[{"id":"https://openalex.org/C2780050583","wikidata":"https://www.wikidata.org/wiki/Q2702796","display_name":"Phytohaemagglutinin","level":3,"score":0.8152831792831421},{"id":"https://openalex.org/C114684123","wikidata":"https://www.wikidata.org/wiki/Q419458","display_name":"CD3","level":4,"score":0.5614862442016602},{"id":"https://openalex.org/C2780252810","wikidata":"https://www.wikidata.org/wiki/Q1455316","display_name":"Immunosuppression","level":2,"score":0.5501018762588501},{"id":"https://openalex.org/C2777761686","wikidata":"https://www.wikidata.org/wiki/Q715347","display_name":"Lymphocyte","level":2,"score":0.5466206669807434},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.531760573387146},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.49557673931121826},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4947373569011688},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.4726867973804474},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.4550810754299164},{"id":"https://openalex.org/C2992881475","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T lymphocyte","level":3,"score":0.45438870787620544},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.45066818594932556},{"id":"https://openalex.org/C19869320","wikidata":"https://www.wikidata.org/wiki/Q419277","display_name":"Concanavalin A","level":3,"score":0.4197281002998352},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.41410335898399353},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.3857775330543518},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.3825925588607788},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.357962429523468},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3568035662174225},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.25222247838974},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08525833487510681},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007070","descriptor_name":"Immunoglobulin A","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007165","descriptor_name":"Immunosuppression Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008213","descriptor_name":"Lymphocyte Activation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008934","descriptor_name":"Mitogens","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D016030","descriptor_name":"Kidney Transplantation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016853","descriptor_name":"Muromonab-CD3","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017252","descriptor_name":"CD3 Complex","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1111/j.1365-2249.1995.tb05526.x","doi":"https://doi.org/10.1111/j.1365-2249.1995.tb05526.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1365-2249.1995.tb05526.x","pdf_url":null,"source":{"id":"https://openalex.org/S11896317","display_name":"Clinical & Experimental Immunology","issn_l":"0009-9104","issn":["0009-9104","1365-2249"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Experimental Immunology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1534302","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1534302","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Exp Immunol","raw_type":"Text"},{"id":"pmid:7851005","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7851005","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and experimental immunology","raw_type":"Journal Article"},{"id":"pmh:oai:pure.amsterdamumc.nl:openaire_cris_publications/e4011591-755e-48db-b705-dd98776dd9db","doi":null,"is_oa":false,"landing_page_url":"https://pure.amsterdamumc.nl/en/publications/e4011591-755e-48db-b705-dd98776dd9db","pdf_url":null,"source":{"id":"https://openalex.org/S7407055222","display_name":"Pure Amsterdam UMC","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Parlevliet, K J, Chamuleau, M E, Yong, S L, Raasveld, M H, ten Berge, I J & Schellekens, P T 1995, 'Effects of anti-CD3 monoclonal antibodies on functional activity of lymphocytes: studies in vivo and in vitro', Clinical and experimental immunology, vol. 99, no. 2, pp. 155-159.","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:amcpub:oai:pure.amc.nl:publications/0bdb8f02-041c-415e-907b-24963422f22d","doi":null,"is_oa":false,"landing_page_url":"https://pure.amc.nl/en/publications/effects-of-anticd3-monoclonal-antibodies-on-functional-activity-of-lymphocytes-studies-in-vivo-and-in-vitro(0bdb8f02-041c-415e-907b-24963422f22d).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Clinical and experimental immunology, 99(2), 155 - 159. Wiley-Blackwell","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:1534302","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1534302","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Exp Immunol","raw_type":"Text"},"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321643","display_name":"Nierstichting","ror":"https://ror.org/020k6v967"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1495237724","https://openalex.org/W1601717539","https://openalex.org/W1963893525","https://openalex.org/W1986010227","https://openalex.org/W1986495665","https://openalex.org/W1987767631","https://openalex.org/W1990529390","https://openalex.org/W1995043914","https://openalex.org/W2002377882","https://openalex.org/W2004469794","https://openalex.org/W2013185591","https://openalex.org/W2017714449","https://openalex.org/W2030655587","https://openalex.org/W2035938515","https://openalex.org/W2043150569","https://openalex.org/W2047859678","https://openalex.org/W2049121901","https://openalex.org/W2053595623","https://openalex.org/W2060654838","https://openalex.org/W2073302853","https://openalex.org/W2074011660","https://openalex.org/W2114355195","https://openalex.org/W2332022311","https://openalex.org/W2398676037","https://openalex.org/W2401290061","https://openalex.org/W2405839966","https://openalex.org/W2410837364","https://openalex.org/W2416734133","https://openalex.org/W4233298376","https://openalex.org/W4321835896","https://openalex.org/W6712585934","https://openalex.org/W6714672341"],"related_works":["https://openalex.org/W2283756106","https://openalex.org/W1977107001","https://openalex.org/W1963893525","https://openalex.org/W2070714215","https://openalex.org/W2082419289","https://openalex.org/W2018870705","https://openalex.org/W1641258807","https://openalex.org/W2472914530","https://openalex.org/W2024306798","https://openalex.org/W2113956841"],"abstract_inverted_index":{"Lymphocyte":[0],"functional":[1],"activity":[2],"was":[3,65,76],"tested":[4,110],"in":[5,101,111],"38":[6],"renal":[7],"transplant":[8],"recipients":[9],"receiving":[10],"induction":[11],"treatment":[12,35,60,79],"with":[13,36,47,61,80,192],"various":[14],"anti-CD3":[15,22,28],"MoAbs,":[16,83],"i.e.":[17],"OKT3,":[18,122],"T3.G2a":[19,92,135,152,171],"(an":[20,26],"IgG2a":[21],"MoAb)":[23],"or":[24,117],"T3.A":[25,62,123,163],"IgA":[27],"MoAb":[29,100],"of":[30,50,89,99,114,162,179,190,201],"the":[31,48,86,97,159,180,202],"same":[32],"idiotype).":[33],"During":[34],"OKT3":[37,90,137,150],"and":[38,91,104,124,136,151],"T3.G2a,":[39],"lymphocyte":[40,53,71,119],"response":[41,64,75],"to":[42,209],"phytohaemagglutinin-P":[43],"(PHA),":[44],"as":[45,187],"determined":[46],"use":[49],"a":[51,69,139,188],"whole-blood":[52],"culture":[54,72,102],"technique,":[55,73],"decreased":[56],"significantly.":[57],"However,":[58,145],"during":[59,78],"PHA":[63,74],"not":[66],"affected.":[67],"Using":[68],"conventional":[70],"unchanged":[77],"all":[81],"three":[82],"indicating":[84],"that":[85,128,158],"immunosuppressive":[87,141,160,174],"effect":[88,142,161,175],"is":[93,105,164],"probably":[94],"dependent":[95],"upon":[96],"presence":[98],"medium":[103],"reversible.":[106],"In":[107],"addition,":[108],"we":[109],"vitro":[112],"inhibition":[113],"aspecific":[115],"mitogen-":[116],"antigen-induced":[118],"stimulation":[120],"by":[121,166],"T3.G2a.":[125],"It":[126],"appeared":[127],"at":[129,146],"low":[130,169],"concentrations":[131,148,170,199],"(<":[132],"25":[133],"ng/ml)":[134],"exerted":[138],"stronger":[140],"than":[143],"T3.A.":[144],"higher":[147,198],"T3.A,":[149],"were":[153],"equally":[154],"immunosuppressive.":[155],"We":[156],"conclude":[157],"caused":[165],"blindfolding.":[167],"At":[168,197],"exerts":[172],"its":[173],"mainly":[176],"through":[177],"modulation":[178],"CD3":[181],"and/or":[182],"T":[183],"cell":[184,204],"receptor":[185,205],"complex,":[186],"result":[189],"interaction":[191],"Fc":[193],"receptors":[194],"on":[195],"monocytes.":[196],"blindfolding":[200],"CD3/T":[203],"complex":[206],"may":[207],"contribute":[208],"immunosuppression.":[210]},"counts_by_year":[{"year":2018,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}