{"id":"https://openalex.org/W2046976948","doi":"https://doi.org/10.1055/s-2005-857951","title":"Die Effizienz der Behandlung der Schizophrenie mit Ziprasidon im Vergleich zu anderen Neuroleptika unter Ber\u00fccksichtigung von Arzneimittelnebenwirkungen und Noncompliance","display_name":"Die Effizienz der Behandlung der Schizophrenie mit Ziprasidon im Vergleich zu anderen Neuroleptika unter Ber\u00fccksichtigung von Arzneimittelnebenwirkungen und Noncompliance","publication_year":2005,"publication_date":"2005-04-08","ids":{"openalex":"https://openalex.org/W2046976948","doi":"https://doi.org/10.1055/s-2005-857951","mag":"2046976948"},"language":"de","primary_location":{"id":"doi:10.1055/s-2005-857951","doi":"https://doi.org/10.1055/s-2005-857951","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2005-857951","pdf_url":null,"source":{"id":"https://openalex.org/S4210194249","display_name":"Gesundheits\u00f6konomie & Qualit\u00e4tsmanagement","issn_l":"1432-2625","issn":["1432-2625","1439-4049"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["jufo-1","norway-1","poland-40","russia-white-list-4"],"host_organization":"https://openalex.org/P4310321135","host_organization_name":"Georg Thieme Verlag","host_organization_lineage":["https://openalex.org/P4310321135","https://openalex.org/P4310320000"],"host_organization_lineage_names":["Georg Thieme Verlag","Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gesundheits\u00f6konomie & Qualit\u00e4tsmanagement","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053128801","display_name":"Hans\u2010Peter Volz","orcid":"https://orcid.org/0000-0001-5438-8918","observed_orcids":["https://orcid.org/0000-0001-5438-8918"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H.-P Volz","raw_affiliation_strings":["Krankenhaus f\u00fcr Psychiatrie und Psychotherapie, Schloss Werneck, Werneck"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Krankenhaus f\u00fcr Psychiatrie und Psychotherapie, Schloss Werneck, Werneck","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108350230","display_name":"Michael Sadre-Chirazi-Stark","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160608","display_name":"Asklepios","ror":"https://ror.org/055tk9p53","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210160608"]},{"id":"https://openalex.org/I4210162578","display_name":"Asklepios Kliniken Hamburg","ror":"https://ror.org/05f8ejd38","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210162578"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M Sadre-Chirazi-Stark","raw_affiliation_strings":["Abt. f\u00fcr Psychiatrie und Psychotherapie, Asklepios Westklinikum, Hamburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Abt. f\u00fcr Psychiatrie und Psychotherapie, Asklepios Westklinikum, Hamburg","institution_ids":["https://openalex.org/I4210160608","https://openalex.org/I4210162578"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020626316","display_name":"Ansgar Resch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210100293","display_name":"Pfizer (Germany)","ror":"https://ror.org/00m8w3m39","country_code":"DE","type":"company","lineage":["https://openalex.org/I180857899","https://openalex.org/I4210100293"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"A Resch","raw_affiliation_strings":["Pfizer GmbH, Karlsruhe"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pfizer GmbH, Karlsruhe","institution_ids":["https://openalex.org/I4210100293"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1676,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.55160982,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"10","issue":null,"first_page":"96","last_page":"101"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9204000234603882,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9204000234603882,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.07259999960660934,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T13944","display_name":"Psychiatric care and mental health services","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ziprasidone","display_name":"ziprasidone","score":0.8840000033378601},{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.9810000061988831},{"id":"https://openalex.org/keywords/antipsychotic-drugs","display_name":"antipsychotic drugs","score":0.7940000295639038},{"id":"https://openalex.org/keywords/haloperidol","display_name":"haloperidol","score":0.871999979019165},{"id":"https://openalex.org/keywords/risperidone","display_name":"risperidone","score":1.0},{"id":"https://openalex.org/keywords/olanzapine","display_name":"olanzapine","score":1.0},{"id":"https://openalex.org/keywords/cost-effectiveness","display_name":"cost-effectiveness","score":0.8019999861717224},{"id":"https://openalex.org/keywords/adverse-drug-reactions","display_name":"adverse drug reactions","score":0.699999988079071},{"id":"https://openalex.org/keywords/akathisia","display_name":"akathisia","score":0.9679999947547913},{"id":"https://openalex.org/keywords/extrapyramidal-symptoms","display_name":"extrapyramidal symptoms","score":0.9879999756813049},{"id":"https://openalex.org/keywords/weight-gain","display_name":"weight gain","score":0.9679999947547913},{"id":"https://openalex.org/keywords/medication-non-adherence","display_name":"medication non-adherence","score":0.8349999785423279},{"id":"https://openalex.org/keywords/health-insurance-perspective","display_name":"health insurance perspective","score":0.5230000019073486}],"concepts":[{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.8259657621383667},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.5216313004493713},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.418593168258667}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1055/s-2005-857951","doi":"https://doi.org/10.1055/s-2005-857951","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2005-857951","pdf_url":null,"source":{"id":"https://openalex.org/S4210194249","display_name":"Gesundheits\u00f6konomie & Qualit\u00e4tsmanagement","issn_l":"1432-2625","issn":["1432-2625","1439-4049"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["jufo-1","norway-1","poland-40","russia-white-list-4"],"host_organization":"https://openalex.org/P4310321135","host_organization_name":"Georg Thieme Verlag","host_organization_lineage":["https://openalex.org/P4310321135","https://openalex.org/P4310320000"],"host_organization_lineage_names":["Georg Thieme Verlag","Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gesundheits\u00f6konomie & Qualit\u00e4tsmanagement","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2386597787","https://openalex.org/W2004941407","https://openalex.org/W149781021","https://openalex.org/W2086266279","https://openalex.org/W2055124622","https://openalex.org/W2014466186","https://openalex.org/W2615557588","https://openalex.org/W2767184049","https://openalex.org/W2076806399","https://openalex.org/W2158850341"],"abstract_inverted_index":{"Zielsetzung:":[0],"Die":[1,23,120,151],"Effizienz":[2],"der":[3,5,46,48,91,163,165,171,176],"Pharmakotherapie":[4],"Schizophrenie":[6],"mit":[7,14,153],"Ziprasidon":[8,105,154],"wurde":[9,25,88,97],"im":[10,64],"Rahmen":[11],"einer":[12],"Kosten-Effektivit\u00e4ts-Analyse":[13],"den":[15,132,157],"Alternativen":[16,134],"Haloperidol,":[17],"Risperidon":[18,141],"und":[19,61,74,116],"Olanzapin":[20,144],"verglichen.":[21],"Methodik:":[22],"Schizophreniebehandlung":[24],"\u00fcber":[26],"einen":[27],"Zeithorizont":[28],"von":[29,72,77,80],"einem":[30],"Jahr":[31],"mittels":[32],"eines":[33],"Markov-Modells":[34],"simuliert.":[35],"Effektivit\u00e4tsparameter":[36],"war":[37,82],"die":[38,89,99,174],"r\u00fcckfallfreie":[39,111],"Zeit":[40,112],"in":[41],"Monaten.":[42],"Es":[43],"wurden":[44],"neben":[45],"Wirksamkeit":[47],"Therapiealternativen":[49],"auch":[50,98,169],"deren":[51],"unerw\u00fcnschte":[52],"Arzneimittelwirkungen":[53],"(UAW)":[54],"Akathisie,":[55],"andere":[56],"extrapyramidale":[57],"Symptome":[58],"(EPS),":[59],"Gewichtszunahme":[60],"Prolaktin-abh\u00e4ngige":[62],"Nebenwirkungen":[63],"Modell":[65],"ber\u00fccksichtigt.":[66],"Der":[67],"Zusammenhang":[68],"zwischen":[69],"dem":[70,75],"Auftreten":[71,76],"UAWs":[73],"R\u00fcckf\u00e4llen":[78],"infolge":[79],"Noncompliance":[81],"zentraler":[83],"Bestandteil":[84],"des":[85],"Modells.":[86],"Prim\u00e4r":[87],"Perspektive":[90,101,164,173],"Gesetzlichen":[92,166],"Krankenversicherung":[93,167],"eingenommen.":[94],"Dar\u00fcber":[95],"hinaus":[96],"gesundheitspolitische":[100],"ber\u00fccksichtigt":[102],".":[103],"Ergebnisse:":[104],"zeichnet":[106],"sich":[107],"durch":[108],"eine":[109],"l\u00e4ngere":[110],"sowie":[113],"geringere":[114],"Gesamt-":[115],"effektivit\u00e4tsadjustierte":[117],"Kosten":[118,123],"aus.":[119],"effektivit\u00e4tsadjustierten":[121],"direkten":[122],"sind":[124],"f\u00fcr":[125],"Patienten":[126],"unter":[127,156],"Ziprasidon-Therapie":[128],"niedriger":[129],"als":[130,168],"bei":[131],"anderen":[133],"(Ziprasidon":[135],"2370":[136],"\u20ac,":[137,140,143,146],"Haloperidol":[138],"3054":[139],"2456":[142],"2514":[145],"pro":[147],"r\u00fcckfallfreien":[148],"Monat).":[149],"Schlussfolgerung:":[150],"Schizophrenietherapie":[152],"ist":[155],"hier":[158],"getroffenen":[159],"Annahmen":[160],"sowohl":[161],"aus":[162,170],"gesundheitspolitischen":[172],"effizienteste":[175],"betrachteten":[177],"Alternativen.":[178]},"counts_by_year":[{"year":2013,"cited_by_count":1}],"updated_date":"2026-09-25T08:18:29.962427","created_date":"2016-06-24T00:00:00"}