{"id":"https://openalex.org/W2046858236","doi":"https://doi.org/10.1182/blood.v99.8.2740","title":"Receptor tyrosine kinase, EphB4 (HTK), accelerates differentiation of select human hematopoietic cells","display_name":"Receptor tyrosine kinase, EphB4 (HTK), accelerates differentiation of select human hematopoietic cells","publication_year":2002,"publication_date":"2002-04-15","ids":{"openalex":"https://openalex.org/W2046858236","doi":"https://doi.org/10.1182/blood.v99.8.2740","mag":"2046858236","pmid":"https://pubmed.ncbi.nlm.nih.gov/11929761"},"language":"en","primary_location":{"id":"doi:10.1182/blood.v99.8.2740","doi":"https://doi.org/10.1182/blood.v99.8.2740","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v99.8.2740","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101470152","display_name":"Zheng\u2010Yu Wang","orcid":"https://orcid.org/0000-0002-8827-2806","observed_orcids":["https://orcid.org/0000-0002-8827-2806"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhengyu Wang","raw_affiliation_strings":["From the Experimental Hematology, AIDS Research Center and MGH Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Experimental Hematology, AIDS Research Center and MGH Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035909818","display_name":"Nobuyuki Miura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nobuyuki Miura","raw_affiliation_strings":["From the Experimental Hematology, AIDS Research Center and MGH Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Experimental Hematology, AIDS Research Center and MGH Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045544994","display_name":"Andres Bonelli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andres Bonelli","raw_affiliation_strings":["From the Experimental Hematology, AIDS Research Center and MGH Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Experimental Hematology, AIDS Research Center and MGH Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057334357","display_name":"Pamela Mole","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pamela Mole","raw_affiliation_strings":["From the Experimental Hematology, AIDS Research Center and MGH Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Experimental Hematology, AIDS Research Center and MGH Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079013323","display_name":"Nadia Carlesso","orcid":"https://orcid.org/0000-0002-5131-9885","observed_orcids":["https://orcid.org/0000-0002-5131-9885"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nadia Carlesso","raw_affiliation_strings":["From the Experimental Hematology, AIDS Research Center and MGH Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Experimental Hematology, AIDS Research Center and MGH Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027997380","display_name":"Douglas P. Olson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Douglas P. Olson","raw_affiliation_strings":["From the Experimental Hematology, AIDS Research Center and MGH Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Experimental Hematology, AIDS Research Center and MGH Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083648953","display_name":"David T. Scadden","orcid":"https://orcid.org/0000-0001-9821-7133","observed_orcids":["https://orcid.org/0000-0001-9821-7133"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David T. Scadden","raw_affiliation_strings":["From the Experimental Hematology, AIDS Research Center and MGH Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Experimental Hematology, AIDS Research Center and MGH Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5500,"currency":"USD","value_usd":5500},"apc_paid":null,"fwci":1.8971,"has_fulltext":false,"cited_by_count":52,"citation_normalized_percentile":{"value":0.86229675,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"99","issue":"8","first_page":"2740","last_page":"2747"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.5648999810218811,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.5648999810218811,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12061","display_name":"Axon Guidance and Neuronal Signaling","score":0.15369999408721924,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.03539999946951866,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ephb4","display_name":"EphB4","score":0.9819999933242798},{"id":"https://openalex.org/keywords/ephrin-b2","display_name":"ephrin-B2","score":0.8690000176429749},{"id":"https://openalex.org/keywords/receptor-tyrosine-kinases","display_name":"receptor tyrosine kinase","score":0.9350000023841858},{"id":"https://openalex.org/keywords/hematopoiesis","display_name":"hematopoiesis","score":0.8059999942779541},{"id":"https://openalex.org/keywords/megakaryopoiesis","display_name":"megakaryopoiesis","score":0.9589999914169312},{"id":"https://openalex.org/keywords/erythroid-differentiation","display_name":"erythroid differentiation","score":0.9909999966621399},{"id":"https://openalex.org/keywords/cd34-cells","display_name":"CD34+ cells","score":0.8090000152587891},{"id":"https://openalex.org/keywords/umbilical-cord-blood","display_name":"umbilical cord blood","score":0.9490000009536743},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.8349999785423279},{"id":"https://openalex.org/keywords/genistein","display_name":"genistein","score":0.6790000200271606},{"id":"https://openalex.org/keywords/tyrosine-kinase-inhibition","display_name":"tyrosine kinase inhibition","score":0.8610000014305115},{"id":"https://openalex.org/keywords/long-term-culture-initiating-cells","display_name":"long-term culture-initiating cells","score":0.8309999704360962}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.72548508644104},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.6264873147010803},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.6263889074325562},{"id":"https://openalex.org/C10205521","wikidata":"https://www.wikidata.org/wiki/Q4035578","display_name":"CD34","level":3,"score":0.6018056273460388},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.5843214392662048},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.55097496509552},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.5125026702880859},{"id":"https://openalex.org/C148738053","wikidata":"https://www.wikidata.org/wiki/Q210861","display_name":"Cellular differentiation","level":3,"score":0.5052650570869446},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.4520355463027954},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.38281944394111633},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.35872286558151245},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.32802116870880127},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08003014326095581},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004789","descriptor_name":"Enzyme Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005312","descriptor_name":"Fetal Blood","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D005822","descriptor_name":"Genetic Vectors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006410","descriptor_name":"Hematopoiesis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008533","descriptor_name":"Megakaryocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D008533","descriptor_name":"Megakaryocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012190","descriptor_name":"Retroviridae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014161","descriptor_name":"Transduction, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015672","descriptor_name":"Erythroid Precursor Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D015672","descriptor_name":"Erythroid Precursor Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018952","descriptor_name":"Antigens, CD34","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019070","descriptor_name":"Cell Lineage","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1182/blood.v99.8.2740","doi":"https://doi.org/10.1182/blood.v99.8.2740","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v99.8.2740","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},{"id":"pmid:11929761","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11929761","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8048999905586243}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W78943186","https://openalex.org/W214380766","https://openalex.org/W1483752328","https://openalex.org/W1522354664","https://openalex.org/W1538762819","https://openalex.org/W1543011513","https://openalex.org/W1546821979","https://openalex.org/W1596240955","https://openalex.org/W1605009719","https://openalex.org/W1808450763","https://openalex.org/W1874275835","https://openalex.org/W1965779501","https://openalex.org/W1972172786","https://openalex.org/W1981589031","https://openalex.org/W1986559037","https://openalex.org/W1991558418","https://openalex.org/W1992490180","https://openalex.org/W1993498456","https://openalex.org/W1994666296","https://openalex.org/W1994801491","https://openalex.org/W1996430165","https://openalex.org/W2001627828","https://openalex.org/W2001879388","https://openalex.org/W2010255447","https://openalex.org/W2013758383","https://openalex.org/W2032359283","https://openalex.org/W2034064964","https://openalex.org/W2035595755","https://openalex.org/W2037036138","https://openalex.org/W2043508733","https://openalex.org/W2045247659","https://openalex.org/W2046516822","https://openalex.org/W2049380625","https://openalex.org/W2065512985","https://openalex.org/W2066888615","https://openalex.org/W2069019173","https://openalex.org/W2079859497","https://openalex.org/W2082494746","https://openalex.org/W2083158374","https://openalex.org/W2083502999","https://openalex.org/W2093498435","https://openalex.org/W2094842547","https://openalex.org/W2110863171","https://openalex.org/W2124213741","https://openalex.org/W2154343067","https://openalex.org/W2169685423","https://openalex.org/W2285974307","https://openalex.org/W2294953816","https://openalex.org/W2343908132","https://openalex.org/W2396426755","https://openalex.org/W2397380447","https://openalex.org/W2409658554","https://openalex.org/W2409919765","https://openalex.org/W4229680502","https://openalex.org/W6648717641"],"related_works":["https://openalex.org/W1994318749","https://openalex.org/W2134893174","https://openalex.org/W2058198884","https://openalex.org/W2343908132","https://openalex.org/W1582577946","https://openalex.org/W1992838550","https://openalex.org/W2010826871","https://openalex.org/W2126560927","https://openalex.org/W2082809735","https://openalex.org/W1995829644"],"abstract_inverted_index":{"EphB4":[0,21,71,85,109,123,133,158,182,208],"(HTK)":[1],"and":[2,10,33,62,76,117,147,212,215,223],"its":[3],"ligand,":[4],"ephrinB2,":[5],"are":[6],"critical":[7],"for":[8],"angiogenesis":[9,61,222],"result":[11],"in":[12,18,25,41,50,86,111,189],"fatal":[13],"abnormalities":[14],"of":[15,78,89,115,151,156,167,186],"capillary":[16],"formation":[17],"null":[19],"mice.":[20],"was":[22],"originally":[23],"identified":[24],"human":[26,80],"bone":[27,51],"marrow":[28,52],"CD34(+)":[29,105],"cells":[30,106,142,150,188],"by":[31,139,163,172,202],"us":[32],"has":[34],"since":[35],"been":[36],"reported":[37],"to":[38],"be":[39,161,217],"expressed":[40,49,84],"erythroid":[42,118,213],"progenitors,":[43],"whereas":[44],"the":[45,57,74,112,173,184],"ligand":[46],"ephrinB2":[47],"is":[48],"stromal":[53],"cells.":[54,82,207],"Reasoning":[55],"that":[56,181],"developmental":[58],"relationship":[59],"between":[60,221],"hematopoiesis":[63],"implies":[64],"common":[65,203],"regulatory":[66],"molecules,":[67],"we":[68],"assessed":[69],"whether":[70],"signaling":[72],"influences":[73],"function":[75],"phenotype":[77],"primitive":[79,135,187],"hematopoietic":[81],"Ectopically":[83],"cell":[87,145,153],"lines":[88],"restricted":[90],"differentiation":[91,185,214],"potential":[92],"promoted":[93],"megakaryocytic":[94,116,211],"differentiation,":[95],"but":[96,193],"not":[97],"granulocytic":[98],"or":[99,143,171],"monocytic":[100],"differentiation.":[101],"Primary":[102],"cord":[103],"blood":[104],"transduced":[107],"with":[108,122,205],"resulted":[110],"elevated":[113],"expression":[114,159],"specific":[119],"markers,":[120],"consistent":[121],"selectively":[124],"enhancing":[125],"some":[126],"lineage-committed":[127],"progenitors.":[128],"In":[129],"less":[130],"mature":[131],"cells,":[132,136],"depleted":[134],"as":[137],"measured":[138],"long-term":[140],"culture-initiating":[141],"CD34(+)CD38(-)":[144],"numbers,":[146],"increased":[148],"progenitor":[149,197],"multiple":[152],"types.":[154],"Effects":[155],"ectopic":[157],"could":[160],"abrogated":[162],"either":[164],"targeted":[165],"mutations":[166],"select":[168,196],"tyrosine":[169,174],"residues":[170],"kinase":[175],"inhibitor,":[176],"genistein.":[177],"These":[178],"data":[179],"indicate":[180],"accelerates":[183],"a":[190,218],"nonlineage-restricted":[191],"manner":[192],"alters":[194],"only":[195],"populations,":[198],"influencing":[199],"lineages":[200],"linked":[201],"ancestry":[204],"endothelial":[206],"enforces":[209],"preferential":[210],"may":[216],"molecular":[219],"bridge":[220],"hematopoiesis.":[224]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}
