{"id":"https://openalex.org/W2046792007","doi":"https://doi.org/10.1111/j.1524-4733.2007.00209.x","title":"Cost-Effectiveness of Pemetrexed Plus Cisplatin: Malignant Pleural Mesothelioma Treatment in UK Clinical Practice","display_name":"Cost-Effectiveness of Pemetrexed Plus Cisplatin: Malignant Pleural Mesothelioma Treatment in UK Clinical Practice","publication_year":2007,"publication_date":"2007-06-26","ids":{"openalex":"https://openalex.org/W2046792007","doi":"https://doi.org/10.1111/j.1524-4733.2007.00209.x","mag":"2046792007","pmid":"https://pubmed.ncbi.nlm.nih.gov/18237355"},"language":"en","primary_location":{"id":"doi:10.1111/j.1524-4733.2007.00209.x","doi":"https://doi.org/10.1111/j.1524-4733.2007.00209.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1524-4733.2007.00209.x","pdf_url":"https://www.valueinhealthjournal.com/article/S1098-3015(10)60491-3/pdf","source":{"id":"https://openalex.org/S678965","display_name":"Value in Health","issn_l":"1098-3015","issn":["1098-3015","1524-4733"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["abdc-a","anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Value in Health","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.valueinhealthjournal.com/article/S1098-3015(10)60491-3/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042140355","display_name":"Anna Cordony","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108991","display_name":"IQVIA (United States)","ror":"https://ror.org/01mk44223","country_code":"US","type":"company","lineage":["https://openalex.org/I4210108991"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Anna Cordony","raw_affiliation_strings":["M-TAG Pty Ltd, A Unit of IMS Health, St Leonards, NSW, Australia. acordony@au.imshealth.com","M-TAG Pty Ltd, A Unit of IMS Health, St Leonards NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"M-TAG Pty Ltd, A Unit of IMS Health, St Leonards, NSW, Australia. acordony@au.imshealth.com","institution_ids":["https://openalex.org/I4210108991"]},{"raw_affiliation_string":"M-TAG Pty Ltd, A Unit of IMS Health, St Leonards NSW, Australia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001772832","display_name":"Corinne Le Reun","orcid":"https://orcid.org/0000-0001-5253-239X","observed_orcids":["https://orcid.org/0000-0001-5253-239X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Corinne Le Reun","raw_affiliation_strings":["M-TAG Pty Ltd, A Unit of IMS Health, St Leonards NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"M-TAG Pty Ltd, A Unit of IMS Health, St Leonards NSW, Australia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047543694","display_name":"Antje M. Smala","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Antje Smala","raw_affiliation_strings":["M-TAG Pty Ltd, A Unit of IMS Health, St Leonards NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"M-TAG Pty Ltd, A Unit of IMS Health, St Leonards NSW, Australia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059850025","display_name":"James Thomas Symanowski","orcid":"https://orcid.org/0000-0003-2495-8822","observed_orcids":["https://orcid.org/0000-0003-2495-8822"]},"institutions":[{"id":"https://openalex.org/I168537998","display_name":"Eli Lilly (United States)","ror":"https://ror.org/01qat3289","country_code":"US","type":"company","lineage":["https://openalex.org/I168537998"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James T. Symanowski","raw_affiliation_strings":["Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN, USA","institution_ids":["https://openalex.org/I168537998"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025956770","display_name":"Jessamy Watkins","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210095227","display_name":"Eli Lilly (United Kingdom)","ror":"https://ror.org/00psab413","country_code":"GB","type":"company","lineage":["https://openalex.org/I168537998","https://openalex.org/I4210095227"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jessamy Watkins","raw_affiliation_strings":["Eli Lilly and Company Ltd, Lilly House, Basingstoke, Hampshire, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eli Lilly and Company Ltd, Lilly House, Basingstoke, Hampshire, UK","institution_ids":["https://openalex.org/I4210095227"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5042140355"],"corresponding_institution_ids":["https://openalex.org/I4210108991"],"apc_list":{"value":4000,"currency":"USD","value_usd":4000},"apc_paid":null,"fwci":0.5396,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.74384221,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"11","issue":"1","first_page":"4","last_page":"12"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11026","display_name":"Occupational and environmental lung diseases","score":0.9053000211715698,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11026","display_name":"Occupational and environmental lung diseases","score":0.9053000211715698,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.08160000294446945,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T12708","display_name":"Economic and Financial Impacts of Cancer","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/malignant-pleural-mesothelioma","display_name":"malignant pleural mesothelioma","score":0.984000027179718},{"id":"https://openalex.org/keywords/pemetrexed","display_name":"pemetrexed","score":0.9800000190734863},{"id":"https://openalex.org/keywords/cisplatin","display_name":"cisplatin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cost-effectiveness","display_name":"cost-effectiveness","score":0.9179999828338623},{"id":"https://openalex.org/keywords/vinorelbine","display_name":"vinorelbine","score":0.9959999918937683},{"id":"https://openalex.org/keywords/quality-adjusted-life-years","display_name":"quality-adjusted life years","score":0.9309999942779541},{"id":"https://openalex.org/keywords/life-years-gained","display_name":"life-years gained","score":0.7820000052452087},{"id":"https://openalex.org/keywords/resource-utilization-health-care","display_name":"resource utilization (health care)","score":0.4259999990463257}],"concepts":[{"id":"https://openalex.org/C2777240266","wikidata":"https://www.wikidata.org/wiki/Q415220","display_name":"Pemetrexed","level":4,"score":0.9588063955307007},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8230776190757751},{"id":"https://openalex.org/C2780350996","wikidata":"https://www.wikidata.org/wiki/Q420532","display_name":"Vinorelbine","level":4,"score":0.6813831329345703},{"id":"https://openalex.org/C2778239845","wikidata":"https://www.wikidata.org/wiki/Q412415","display_name":"Cisplatin","level":3,"score":0.6805880069732666},{"id":"https://openalex.org/C2777407522","wikidata":"https://www.wikidata.org/wiki/Q1077603","display_name":"Mesothelioma","level":2,"score":0.5868791937828064},{"id":"https://openalex.org/C3019080777","wikidata":"https://www.wikidata.org/wiki/Q1754768","display_name":"Cost effectiveness","level":2,"score":0.578597903251648},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5388922095298767},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.520486056804657},{"id":"https://openalex.org/C64332521","wikidata":"https://www.wikidata.org/wiki/Q614165","display_name":"Quality-adjusted life year","level":3,"score":0.4421229362487793},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.43537092208862305},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.3420392870903015},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.33050113916397095},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.0},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000068437","descriptor_name":"Pemetrexed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000964","descriptor_name":"Antimetabolites, Antineoplastic","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000964","descriptor_name":"Antimetabolites, Antineoplastic","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D000964","descriptor_name":"Antimetabolites, Antineoplastic","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002945","descriptor_name":"Cisplatin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D002945","descriptor_name":"Cisplatin","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D002945","descriptor_name":"Cisplatin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D003362","descriptor_name":"Cost-Benefit Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005971","descriptor_name":"Glutamates","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D005971","descriptor_name":"Glutamates","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D005971","descriptor_name":"Glutamates","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006113","descriptor_name":"United Kingdom","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006147","descriptor_name":"Guanine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D006147","descriptor_name":"Guanine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D006147","descriptor_name":"Guanine","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D006147","descriptor_name":"Guanine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008654","descriptor_name":"Mesothelioma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008654","descriptor_name":"Mesothelioma","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D008654","descriptor_name":"Mesothelioma","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D010865","descriptor_name":"Pilot Projects","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010997","descriptor_name":"Pleural Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D010997","descriptor_name":"Pleural Neoplasms","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D010997","descriptor_name":"Pleural Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D014747","descriptor_name":"Vinblastine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D014747","descriptor_name":"Vinblastine","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D014747","descriptor_name":"Vinblastine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D016685","descriptor_name":"Mitomycin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1524-4733.2007.00209.x","doi":"https://doi.org/10.1111/j.1524-4733.2007.00209.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1524-4733.2007.00209.x","pdf_url":"https://www.valueinhealthjournal.com/article/S1098-3015(10)60491-3/pdf","source":{"id":"https://openalex.org/S678965","display_name":"Value in Health","issn_l":"1098-3015","issn":["1098-3015","1524-4733"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["abdc-a","anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Value in Health","raw_type":"journal-article"},{"id":"pmid:18237355","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18237355","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research","raw_type":"Clinical Trial, Phase III"}],"best_oa_location":{"id":"doi:10.1111/j.1524-4733.2007.00209.x","doi":"https://doi.org/10.1111/j.1524-4733.2007.00209.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1524-4733.2007.00209.x","pdf_url":"https://www.valueinhealthjournal.com/article/S1098-3015(10)60491-3/pdf","source":{"id":"https://openalex.org/S678965","display_name":"Value in Health","issn_l":"1098-3015","issn":["1098-3015","1524-4733"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["abdc-a","anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Value in Health","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320307758","display_name":"Eli Lilly and Company","ror":"https://ror.org/01qat3289"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2046792007.pdf","grobid_xml":"https://content.openalex.org/works/W2046792007.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W257531703","https://openalex.org/W1572860679","https://openalex.org/W1579641819","https://openalex.org/W1869777220","https://openalex.org/W1960348144","https://openalex.org/W1984913351","https://openalex.org/W1989131755","https://openalex.org/W2010331461","https://openalex.org/W2026088654","https://openalex.org/W2032016913","https://openalex.org/W2102627969","https://openalex.org/W2107560105","https://openalex.org/W2126125592","https://openalex.org/W2132637325","https://openalex.org/W2147595306","https://openalex.org/W2276175015","https://openalex.org/W2404220055","https://openalex.org/W2915928261"],"related_works":["https://openalex.org/W2136053992","https://openalex.org/W2063525152","https://openalex.org/W2106879636","https://openalex.org/W2399273269","https://openalex.org/W4289717313","https://openalex.org/W2612135557","https://openalex.org/W4317039671","https://openalex.org/W4311332952","https://openalex.org/W4286716251","https://openalex.org/W1971570522"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}