{"id":"https://openalex.org/W2046511347","doi":"https://doi.org/10.1007/s13361-011-0287-5","title":"Differentiation of the Stereochemistry and Anomeric Configuration for 1-3 Linked Disaccharides Via Tandem Mass Spectrometry and 18O-labeling","display_name":"Differentiation of the Stereochemistry and Anomeric Configuration for 1-3 Linked Disaccharides Via Tandem Mass Spectrometry and 18O-labeling","publication_year":2011,"publication_date":"2011-11-17","ids":{"openalex":"https://openalex.org/W2046511347","doi":"https://doi.org/10.1007/s13361-011-0287-5","mag":"2046511347","pmid":"https://pubmed.ncbi.nlm.nih.gov/22095166"},"language":"en","primary_location":{"id":"doi:10.1007/s13361-011-0287-5","doi":"https://doi.org/10.1007/s13361-011-0287-5","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s13361-011-0287-5","pdf_url":null,"source":{"id":"https://openalex.org/S60743949","display_name":"Journal of the American Society for Mass Spectrometry","issn_l":"1044-0305","issn":["1044-0305","1879-1123"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Society for Mass Spectrometry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045938177","display_name":"Chiharu Konda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chiharu Konda","raw_affiliation_strings":["Department of Chemistry, Purdue University, 47907-1393, West Lafayette, IN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Purdue University, 47907-1393, West Lafayette, IN, USA","institution_ids":["https://openalex.org/I219193219"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085907554","display_name":"Brad K. Bendiak","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brad Bendiak","raw_affiliation_strings":["Department of Cell and Developmental Biology, and Program in Structural Biology and Biophysics, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Developmental Biology, and Program in Structural Biology and Biophysics, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA","institution_ids":["https://openalex.org/I51713134","https://openalex.org/I921990950"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062534695","display_name":"Yu Xia","orcid":"https://orcid.org/0000-0001-8694-9900","observed_orcids":["https://orcid.org/0000-0001-8694-9900"]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yu Xia","raw_affiliation_strings":["Department of Chemistry, Purdue University, 47907-1393, West Lafayette, IN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Purdue University, 47907-1393, West Lafayette, IN, USA","institution_ids":["https://openalex.org/I219193219"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":1.3034,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":{"value":0.76079667,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"23","issue":"2","first_page":"347","last_page":"358"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10683","display_name":"Mass Spectrometry Techniques and Applications","score":0.9824000000953674,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10683","display_name":"Mass Spectrometry Techniques and Applications","score":0.9824000000953674,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10835","display_name":"Carbohydrate Chemistry and Synthesis","score":0.009700000286102295,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.005400000140070915,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/stereochemistry-determination","display_name":"stereochemistry determination","score":0.7450000047683716},{"id":"https://openalex.org/keywords/anomeric-configuration","display_name":"anomeric configuration","score":0.9990000128746033},{"id":"https://openalex.org/keywords/18o-labeling","display_name":"18O labeling","score":0.7390000224113464},{"id":"https://openalex.org/keywords/linear-ion-trap","display_name":"linear ion trap","score":0.6779999732971191},{"id":"https://openalex.org/keywords/tandem-mass-spectrometry","display_name":"tandem mass spectrometry","score":0.8970000147819519},{"id":"https://openalex.org/keywords/glycosidic-bond","display_name":"glycosidic linkage","score":0.6480000019073486}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9549137353897095},{"id":"https://openalex.org/C7947691","wikidata":"https://www.wikidata.org/wiki/Q567575","display_name":"Anomer","level":2,"score":0.7670578956604004},{"id":"https://openalex.org/C31827203","wikidata":"https://www.wikidata.org/wiki/Q874296","display_name":"Tandem mass spectrometry","level":3,"score":0.6767846941947937},{"id":"https://openalex.org/C162356407","wikidata":"https://www.wikidata.org/wiki/Q180809","display_name":"Mass spectrometry","level":2,"score":0.6600784063339233},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.5781600475311279},{"id":"https://openalex.org/C2777814067","wikidata":"https://www.wikidata.org/wiki/Q1752317","display_name":"Tandem","level":2,"score":0.49593743681907654},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.3289593756198883},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004187","descriptor_name":"Disaccharides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D010103","descriptor_name":"Oxygen Isotopes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013237","descriptor_name":"Stereoisomerism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053719","descriptor_name":"Tandem Mass Spectrometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/s13361-011-0287-5","doi":"https://doi.org/10.1007/s13361-011-0287-5","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s13361-011-0287-5","pdf_url":null,"source":{"id":"https://openalex.org/S60743949","display_name":"Journal of the American Society for Mass Spectrometry","issn_l":"1044-0305","issn":["1044-0305","1879-1123"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Society for Mass Spectrometry","raw_type":"journal-article"},{"id":"pmid:22095166","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22095166","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Society for Mass Spectrometry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G8805407705","display_name":"Sequential Degradation of Oligosaccharides from the Reducing End","funder_award_id":"0137986","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320337393","display_name":"Division of Chemistry","ror":"https://ror.org/01ar8dr59"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W1542334133","https://openalex.org/W1820870565","https://openalex.org/W1964723513","https://openalex.org/W1968391302","https://openalex.org/W1972867338","https://openalex.org/W1976165460","https://openalex.org/W1977972652","https://openalex.org/W1984764929","https://openalex.org/W1986873950","https://openalex.org/W1989836820","https://openalex.org/W1992066825","https://openalex.org/W1998135327","https://openalex.org/W1999629817","https://openalex.org/W2003350700","https://openalex.org/W2023475768","https://openalex.org/W2028421938","https://openalex.org/W2029100373","https://openalex.org/W2029193900","https://openalex.org/W2029605325","https://openalex.org/W2032352383","https://openalex.org/W2034242343","https://openalex.org/W2037591188","https://openalex.org/W2052150945","https://openalex.org/W2057037040","https://openalex.org/W2061401352","https://openalex.org/W2070449393","https://openalex.org/W2070474725","https://openalex.org/W2072671787","https://openalex.org/W2073292063","https://openalex.org/W2073637473","https://openalex.org/W2077524816","https://openalex.org/W2082498797","https://openalex.org/W2087031947","https://openalex.org/W2099167813","https://openalex.org/W2110174460","https://openalex.org/W2117672117","https://openalex.org/W2124157967","https://openalex.org/W2124907615","https://openalex.org/W2127425955","https://openalex.org/W2148149567","https://openalex.org/W2150740969","https://openalex.org/W2161190692","https://openalex.org/W2164366495","https://openalex.org/W2237233410","https://openalex.org/W2403524963","https://openalex.org/W2980304717","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2082498797","https://openalex.org/W1984764929","https://openalex.org/W2039272097","https://openalex.org/W2002843776","https://openalex.org/W2070449393","https://openalex.org/W1998135327","https://openalex.org/W1976040605","https://openalex.org/W2050476365","https://openalex.org/W2087031947","https://openalex.org/W2779668254"],"abstract_inverted_index":{"Collision-induced":[0],"dissociation":[1,135],"(CID)":[2],"of":[3,34,49,61,87,104,107,125,131,134,140,193,219,226,243],"deprotonated":[4],"hexose-containing":[5],"disaccharides":[6,29,110,222],"(m/z":[7],"341)":[8],"with":[9,30,231,239],"1-2,":[10],"1-4,":[11],"and":[12,46,150,174,223,240],"1-6":[13],"linkages":[14,70],"yields":[15],"product":[16,157],"ions":[17,37,64,90],"at":[18,121],"m/z":[19,35,62,88,155,194,211],"221,":[20],"which":[21,197],"have":[22,198],"been":[23],"identified":[24,237],"as":[25],"glycosyl-glycolaldehyde":[26,200],"anions.":[27],"From":[28],"these":[31],"linkages,":[32],"CID":[33,79,103,149,189,218],"221":[36,63,89,195,212],"produces":[38],"distinct":[39],"fragmentation":[40,205],"patterns":[41,206],"that":[42,84,167],"enable":[43],"the":[44,50,96,122,126,132,141,172,181,191,199,224,227,232,244],"stereochemistries":[45],"anomeric":[47,233],"configurations":[48],"non-reducing":[51,182,228],"sugar":[52,128,246],"units":[53],"to":[54,137],"be":[55,66,92],"determined.":[56],"However,":[57],"only":[58],"trace":[59],"quantities":[60],"can":[65,91],"generated":[67],"for":[68,209],"1-3":[69,108,220],"in":[71,95],"Paul":[72],"or":[73],"linear":[74,97],"ion":[75,98,116,151,158,213],"traps,":[76],"preventing":[77],"further":[78],"analysis.":[80],"Here":[81],"we":[82],"demonstrate":[83],"high":[85],"intensities":[86],"built":[93],"up":[94],"trap":[99,117,152],"(Q3)":[100],"from":[101,214],"beam-type":[102,148,188,217],"a":[105,113,164],"series":[106],"linked":[109,221],"conducted":[111],"on":[112],"triple":[114],"quadrupole/linear":[115],"mass":[118],"spectrometer.":[119],"(18)O-labeling":[120,242],"carbonyl":[123,247],"position":[124],"reducing":[127,245],"allowed":[129],"mass-discrimination":[130],"\"sidedness\"":[133],"events":[136],"either":[138],"side":[139],"glycosidic":[142],"linkage.":[143],"Under":[144,184],"relatively":[145],"low":[146],"energy":[147,187,216],"CID,":[153],"an":[154],"223":[156],"containing":[159],"(18)O":[160],"predominated.":[161],"It":[162],"was":[163],"structural":[165,178],"isomer":[166],"fragmented":[168],"quite":[169],"differently":[170],"than":[171],"glycosyl-glycolaldehydes":[173],"did":[175],"not":[176],"provide":[177],"information":[179],"about":[180],"sugar.":[183],"higher":[185,215],"collision":[186],"conditions,":[190],"formation":[192],"ions,":[196],"structures,":[201],"were":[202,207,235],"favored.":[203],"Characteristic":[204],"observed":[208],"each":[210],"stereochemistry":[225],"sugar,":[229],"together":[230],"configuration,":[234],"successfully":[236],"both":[238],"without":[241],"group.":[248]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}