{"id":"https://openalex.org/W2046491276","doi":"https://doi.org/10.1227/01.neu.0000129681.85731.00","title":"Genetic and Cellular Therapies for Cerebral Infarction","display_name":"Genetic and Cellular Therapies for Cerebral Infarction","publication_year":2004,"publication_date":"2004-08-01","ids":{"openalex":"https://openalex.org/W2046491276","doi":"https://doi.org/10.1227/01.neu.0000129681.85731.00","mag":"2046491276","pmid":"https://pubmed.ncbi.nlm.nih.gov/15271234"},"language":"en","primary_location":{"id":"doi:10.1227/01.neu.0000129681.85731.00","doi":"https://doi.org/10.1227/01.neu.0000129681.85731.00","is_oa":false,"landing_page_url":"https://doi.org/10.1227/01.neu.0000129681.85731.00","pdf_url":null,"source":{"id":"https://openalex.org/S111727011","display_name":"Neurosurgery","issn_l":"0148-396X","issn":["0148-396X","1081-1281","1524-4040"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurosurgery","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050281958","display_name":"Oszkar Szentirmai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Oszkar Szentirmai","raw_affiliation_strings":["Laboratory of Genetic and Cellular, Engineering, and Neurosurgical, Service, Massachusetts General, Hospital and Harvard Medical, School, Boston, Massachusetts","Laboratory of Genetic and Cellular Engineering, and Neurosurgical Service, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Genetic and Cellular, Engineering, and Neurosurgical, Service, Massachusetts General, Hospital and Harvard Medical, School, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Laboratory of Genetic and Cellular Engineering, and Neurosurgical Service, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005526815","display_name":"Bob S. Carter","orcid":"https://orcid.org/0000-0002-3586-1324","observed_orcids":["https://orcid.org/0000-0002-3586-1324"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bob S. Carter","raw_affiliation_strings":["Laboratory of Genetic and Cellular, Engineering, and Neurosurgical, Service, Massachusetts General, Hospital and Harvard Medical, School, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Genetic and Cellular, Engineering, and Neurosurgical, Service, Massachusetts General, Hospital and Harvard Medical, School, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4862,"has_fulltext":false,"cited_by_count":24,"citation_normalized_percentile":{"value":0.47017816,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"55","issue":"2","first_page":"283","last_page":"297"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.3698999881744385,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.3698999881744385,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.15369999408721924,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.11100000143051147,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cerebral-infarction","display_name":"cerebral infarction","score":0.8870000243186951},{"id":"https://openalex.org/keywords/stroke","display_name":"stroke","score":0.8489999771118164},{"id":"https://openalex.org/keywords/gene-therapy","display_name":"gene therapy","score":0.8100000023841858},{"id":"https://openalex.org/keywords/cell-therapy","display_name":"cell therapy","score":0.7789999842643738},{"id":"https://openalex.org/keywords/stem-cell-therapy","display_name":"stem cell therapy","score":0.5899999737739563},{"id":"https://openalex.org/keywords/neurogenesis","display_name":"neurogenesis","score":0.5},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.765999972820282},{"id":"https://openalex.org/keywords/intracellular-calcium","display_name":"intracellular calcium","score":0.703000009059906},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.9210000038146973},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.7620000243186951}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7700619697570801},{"id":"https://openalex.org/C111599444","wikidata":"https://www.wikidata.org/wiki/Q213901","display_name":"Genetic enhancement","level":3,"score":0.6170318126678467},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5919657945632935},{"id":"https://openalex.org/C10882517","wikidata":"https://www.wikidata.org/wiki/Q15268054","display_name":"Cell therapy","level":3,"score":0.5690120458602905},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.4930250346660614},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.477937251329422},{"id":"https://openalex.org/C2991719091","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell biology","level":5,"score":0.46152463555336},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.4422125816345215},{"id":"https://openalex.org/C2779389132","wikidata":"https://www.wikidata.org/wiki/Q1533033","display_name":"Stem-cell therapy","level":3,"score":0.42818719148635864},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.4210168123245239},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3278788924217224},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2530895471572876},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2260650396347046},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.2012907862663269},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15850061178207397},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09649011492729187},{"id":"https://openalex.org/C87073359","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryogenesis","level":3,"score":0.0},{"id":"https://openalex.org/C2994278967","wikidata":"https://www.wikidata.org/wiki/Q7314318","display_name":"Reproductive technology","level":4,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002544","descriptor_name":"Cerebral Infarction","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002544","descriptor_name":"Cerebral Infarction","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D002544","descriptor_name":"Cerebral Infarction","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009410","descriptor_name":"Nerve Degeneration","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009410","descriptor_name":"Nerve Degeneration","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D009410","descriptor_name":"Nerve Degeneration","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D009415","descriptor_name":"Nerve Net","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D009416","descriptor_name":"Nerve Regeneration","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015316","descriptor_name":"Genetic Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018014","descriptor_name":"Gene Transfer Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D033581","descriptor_name":"Stem Cell Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064987","descriptor_name":"Cell- and Tissue-Based Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1227/01.neu.0000129681.85731.00","doi":"https://doi.org/10.1227/01.neu.0000129681.85731.00","is_oa":false,"landing_page_url":"https://doi.org/10.1227/01.neu.0000129681.85731.00","pdf_url":null,"source":{"id":"https://openalex.org/S111727011","display_name":"Neurosurgery","issn_l":"0148-396X","issn":["0148-396X","1081-1281","1524-4040"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurosurgery","raw_type":"journal-article"},{"id":"pmid:15271234","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15271234","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurosurgery","raw_type":"Journal Article"},{"id":"pmid:18695566","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18695566","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurosurgery","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9922999739646912}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":119,"referenced_works":["https://openalex.org/W6952946","https://openalex.org/W85412040","https://openalex.org/W348277772","https://openalex.org/W1001064493","https://openalex.org/W1483365010","https://openalex.org/W1484618897","https://openalex.org/W1484963557","https://openalex.org/W1548436366","https://openalex.org/W1595834812","https://openalex.org/W1621991227","https://openalex.org/W1643680178","https://openalex.org/W1859730138","https://openalex.org/W1906569886","https://openalex.org/W1963764076","https://openalex.org/W1967298185","https://openalex.org/W1967958787","https://openalex.org/W1969459114","https://openalex.org/W1970562576","https://openalex.org/W1970895440","https://openalex.org/W1973342484","https://openalex.org/W1982353289","https://openalex.org/W1982701031","https://openalex.org/W1982961252","https://openalex.org/W1984626876","https://openalex.org/W1986949938","https://openalex.org/W1987107175","https://openalex.org/W1988189150","https://openalex.org/W1995266995","https://openalex.org/W1995383043","https://openalex.org/W1996074673","https://openalex.org/W1999269871","https://openalex.org/W2000494655","https://openalex.org/W2000663601","https://openalex.org/W2003014511","https://openalex.org/W2004421565","https://openalex.org/W2004872316","https://openalex.org/W2012038370","https://openalex.org/W2012359897","https://openalex.org/W2012618391","https://openalex.org/W2012658246","https://openalex.org/W2012693239","https://openalex.org/W2013327644","https://openalex.org/W2014512545","https://openalex.org/W2018303730","https://openalex.org/W2021353279","https://openalex.org/W2021657931","https://openalex.org/W2024667339","https://openalex.org/W2030349847","https://openalex.org/W2031236369","https://openalex.org/W2032712543","https://openalex.org/W2033284482","https://openalex.org/W2033562758","https://openalex.org/W2033813530","https://openalex.org/W2034528524","https://openalex.org/W2035176092","https://openalex.org/W2039824179","https://openalex.org/W2039945427","https://openalex.org/W2041112741","https://openalex.org/W2042602135","https://openalex.org/W2042720374","https://openalex.org/W2043627182","https://openalex.org/W2044357647","https://openalex.org/W2045233930","https://openalex.org/W2045835005","https://openalex.org/W2045978113","https://openalex.org/W2048258494","https://openalex.org/W2054507508","https://openalex.org/W2055167426","https://openalex.org/W2058902596","https://openalex.org/W2062362233","https://openalex.org/W2067856703","https://openalex.org/W2069032899","https://openalex.org/W2070614971","https://openalex.org/W2073836556","https://openalex.org/W2076398948","https://openalex.org/W2077704809","https://openalex.org/W2078504883","https://openalex.org/W2080931209","https://openalex.org/W2087426606","https://openalex.org/W2087683746","https://openalex.org/W2087977616","https://openalex.org/W2088212325","https://openalex.org/W2093473585","https://openalex.org/W2095277530","https://openalex.org/W2098015360","https://openalex.org/W2102085111","https://openalex.org/W2114032717","https://openalex.org/W2117775170","https://openalex.org/W2117910392","https://openalex.org/W2120286526","https://openalex.org/W2123351961","https://openalex.org/W2125619731","https://openalex.org/W2126088489","https://openalex.org/W2129000249","https://openalex.org/W2131517482","https://openalex.org/W2134265543","https://openalex.org/W2143662575","https://openalex.org/W2145283772","https://openalex.org/W2149208246","https://openalex.org/W2152732768","https://openalex.org/W2152845218","https://openalex.org/W2153891187","https://openalex.org/W2154104720","https://openalex.org/W2158009878","https://openalex.org/W2162318134","https://openalex.org/W2165824005","https://openalex.org/W2165867905","https://openalex.org/W2167705610","https://openalex.org/W2168272960","https://openalex.org/W2168956313","https://openalex.org/W2281688494","https://openalex.org/W2334461448","https://openalex.org/W2409993982","https://openalex.org/W2414911543","https://openalex.org/W2415526436","https://openalex.org/W3144772954","https://openalex.org/W4254314849","https://openalex.org/W6611763452","https://openalex.org/W7073526656"],"related_works":["https://openalex.org/W2005369912","https://openalex.org/W2006781351","https://openalex.org/W2315184911","https://openalex.org/W1970818914","https://openalex.org/W2746032594","https://openalex.org/W1601416730","https://openalex.org/W2001619373","https://openalex.org/W2121215260","https://openalex.org/W2381501498","https://openalex.org/W4286223757"],"abstract_inverted_index":{"Neurosurgeons,":[0],"working":[1],"as":[2,95],"surgical":[3],"scientists,":[4],"can":[5],"have":[6],"a":[7,34,67],"prominent":[8],"role":[9],"in":[10,79,162,166,192,204,207],"developing":[11],"and":[12,15,27,46,60,72,125,165,180,182,188,218],"implementing":[13],"genetic":[14,26,59],"cellular":[16,28,61,158],"therapies":[17,29,159,226],"for":[18,30,63,69,160,186,224,227],"cerebral":[19,141],"ischemia.":[20],"The":[21],"rapid":[22],"emergence":[23],"of":[24,39,48,58,82,102,108,110,116,122,150,156,174,210],"both":[25],"neural":[31],"regeneration":[32],"warrants":[33],"careful":[35],"analysis":[36],"before":[37],"implementation":[38],"human":[40,167],"studies":[41,151],"to":[42,65,135,139],"understand":[43],"the":[44,56,133,148,154,172,201,208],"pitfalls":[45],"promises":[47],"this":[49,52,80],"strategy.":[50],"In":[51,84,143],"article,":[53],"we":[54,87,146],"review":[55,88],"topic":[57],"therapy":[62,194,220],"stroke":[64,161],"provide":[66,221],"foundation":[68],"practicing":[70],"neurosurgeons":[71],"clinical":[73,190],"scientists":[74],"who":[75],"may":[76],"become":[77],"involved":[78],"type":[81],"work.":[83],"Part":[85,144],"1,":[86],"preclinical":[89],"approaches":[90],"with":[91],"gene":[92,128,219],"transfer,":[93],"such":[94],"1)":[96,171],"improved":[97],"energy":[98],"delivery,":[99],"2)":[100,178],"reduction":[101,115],"intracellular":[103],"calcium":[104],"availability,":[105],"3)":[106,181],"abrogation":[107],"effects":[109],"reactive":[111],"oxygen":[112],"species,":[113],"4)":[114,189],"proinflammatory":[117],"cytokine":[118],"signaling,":[119],"5)":[120],"inhibition":[121],"apoptosis":[123],"mediators,":[124],"6)":[126],"restorative":[127],"therapy,":[129,187],"that":[130,152],"are":[131],"paving":[132],"way":[134],"develop":[136],"new":[137,225],"strategies":[138],"treat":[140],"infarction.":[142],"2,":[145],"discuss":[147],"results":[149],"address":[153],"possibility":[155],"using":[157],"animal":[163],"models":[164],"trials":[168],"by":[169],"reviewing":[170],"basics":[173],"stem":[175,215],"cell":[176,184,193,216],"biology,":[177,217],"exogenous":[179],"endogenous":[183],"sources":[185],"considerations":[191],"applications.":[195],"These":[196],"emerging":[197],"technologies":[198],"based":[199],"on":[200],"advancements":[202],"made":[203],"recent":[205],"years":[206],"fields":[209],"genetics,":[211],"therapeutic":[212],"cloning,":[213],"neuroscience,":[214],"significant":[222],"potential":[223],"stroke.":[228]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
