{"id":"https://openalex.org/W2046084467","doi":"https://doi.org/10.1016/0378-1097(94)90592-4","title":"Genome conservation in Helicobacter mustelae as determined by pulsed-field gel electrophoresis","display_name":"Genome conservation in Helicobacter mustelae as determined by pulsed-field gel electrophoresis","publication_year":1994,"publication_date":"1994-05-01","ids":{"openalex":"https://openalex.org/W2046084467","doi":"https://doi.org/10.1016/0378-1097(94)90592-4","mag":"2046084467","pmid":"https://pubmed.ncbi.nlm.nih.gov/8013879"},"language":"en","primary_location":{"id":"doi:10.1016/0378-1097(94)90592-4","doi":"https://doi.org/10.1016/0378-1097(94)90592-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/0378-1097(94)90592-4","pdf_url":"https://academic.oup.com/femsle/article-pdf/118/1-2/31/19094003/118-1-2-31.pdf","source":{"id":"https://openalex.org/S34954451","display_name":"FEMS Microbiology Letters","issn_l":"0378-1097","issn":["0378-1097","1574-6968"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS Microbiology Letters","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/femsle/article-pdf/118/1-2/31/19094003/118-1-2-31.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082599033","display_name":"Diane E. Taylor","orcid":"https://orcid.org/0009-0002-4940-9352","observed_orcids":["https://orcid.org/0009-0002-4940-9352"]},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Diane E. Taylor","raw_affiliation_strings":["Department of Medical Microbiology and Infectious Diseases, University of Alberta, Edmonton, Canada","Department of Medical Microbiology and Infectious Diseases, 1\u201328 Medical Sciences Building, University of Alberta, Edmonton, Alberta, Canada T6G 2H7"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Microbiology and Infectious Diseases, University of Alberta, Edmonton, Canada","institution_ids":["https://openalex.org/I154425047"]},{"raw_affiliation_string":"Department of Medical Microbiology and Infectious Diseases, 1\u201328 Medical Sciences Building, University of Alberta, Edmonton, Alberta, Canada T6G 2H7","institution_ids":["https://openalex.org/I154425047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023454238","display_name":"Nicholas Chang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Nicholas Chang","raw_affiliation_strings":["Department of Medical Microbiology and Infectious Diseases, 1\u201328 Medical Sciences Building, University of Alberta, Edmonton, Alberta, Canada T6G 2H7"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Microbiology and Infectious Diseases, 1\u201328 Medical Sciences Building, University of Alberta, Edmonton, Alberta, Canada T6G 2H7","institution_ids":["https://openalex.org/I154425047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110088018","display_name":"Nancy S. Taylor","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nancy S. Taylor","raw_affiliation_strings":["Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA 02139, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA 02139, USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024428264","display_name":"James G. Fox","orcid":"https://orcid.org/0000-0001-9307-6116","observed_orcids":["https://orcid.org/0000-0001-9307-6116"]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James G. Fox","raw_affiliation_strings":["Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA 02139, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA 02139, USA","institution_ids":["https://openalex.org/I63966007"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5082599033"],"corresponding_institution_ids":["https://openalex.org/I154425047"],"apc_list":{"value":2500,"currency":"GBP","value_usd":3297},"apc_paid":null,"fwci":1.5268,"has_fulltext":true,"cited_by_count":24,"citation_normalized_percentile":{"value":0.82470368,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"118","issue":"1-2","first_page":"31","last_page":"36"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11688","display_name":"Microbial infections and disease research","score":0.003700000001117587,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10486","display_name":"Salmonella and Campylobacter epidemiology","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/helicobacter-mustelae","display_name":"Helicobacter mustelae","score":1.0},{"id":"https://openalex.org/keywords/genome-conservation","display_name":"genome conservation","score":0.7670000195503235},{"id":"https://openalex.org/keywords/genomic-diversity","display_name":"genomic diversity","score":0.6079999804496765},{"id":"https://openalex.org/keywords/genome-size","display_name":"genome size","score":0.8190000057220459},{"id":"https://openalex.org/keywords/pulsed-field-gel-electrophoresis","display_name":"pulsed-field gel electrophoresis","score":0.8320000171661377},{"id":"https://openalex.org/keywords/rifampicin-resistance","display_name":"rifampicin resistance","score":0.8399999737739563},{"id":"https://openalex.org/keywords/ferrets","display_name":"ferrets","score":0.5860000252723694},{"id":"https://openalex.org/keywords/mink","display_name":"mink","score":0.9850000143051147},{"id":"https://openalex.org/keywords/experimental-infection","display_name":"experimental infection","score":0.5609999895095825}],"concepts":[{"id":"https://openalex.org/C42084846","wikidata":"https://www.wikidata.org/wiki/Q855275","display_name":"Pulsed-field gel electrophoresis","level":4,"score":0.8194875717163086},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.733133852481842},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.6518666744232178},{"id":"https://openalex.org/C116084860","wikidata":"https://www.wikidata.org/wiki/Q48255","display_name":"Gel electrophoresis","level":2,"score":0.5629788637161255},{"id":"https://openalex.org/C17757408","wikidata":"https://www.wikidata.org/wiki/Q4135516","display_name":"genomic DNA","level":3,"score":0.5005924701690674},{"id":"https://openalex.org/C61271108","wikidata":"https://www.wikidata.org/wiki/Q3180866","display_name":"Genome size","level":4,"score":0.4906415045261383},{"id":"https://openalex.org/C2778022156","wikidata":"https://www.wikidata.org/wiki/Q576145","display_name":"Strain (injury)","level":2,"score":0.4381404221057892},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.39027953147888184},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.35842281579971313},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3399497866630554},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.2873792052268982},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.12321275472640991},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.11782309412956238},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11134383082389832}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004269","descriptor_name":"DNA, Bacterial","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D004269","descriptor_name":"DNA, Bacterial","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D005289","descriptor_name":"Ferrets","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D006113","descriptor_name":"United Kingdom","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008907","descriptor_name":"Mink","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008970","descriptor_name":"Molecular Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015183","descriptor_name":"Restriction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016521","descriptor_name":"Electrophoresis, Gel, Pulsed-Field","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016998","descriptor_name":"Helicobacter","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/0378-1097(94)90592-4","doi":"https://doi.org/10.1016/0378-1097(94)90592-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/0378-1097(94)90592-4","pdf_url":"https://academic.oup.com/femsle/article-pdf/118/1-2/31/19094003/118-1-2-31.pdf","source":{"id":"https://openalex.org/S34954451","display_name":"FEMS Microbiology Letters","issn_l":"0378-1097","issn":["0378-1097","1574-6968"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS Microbiology Letters","raw_type":"journal-article"},{"id":"doi:10.1111/j.1574-6968.1994.tb06799.x","doi":"https://doi.org/10.1111/j.1574-6968.1994.tb06799.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1574-6968.1994.tb06799.x","pdf_url":null,"source":{"id":"https://openalex.org/S34954451","display_name":"FEMS Microbiology Letters","issn_l":"0378-1097","issn":["0378-1097","1574-6968"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS Microbiology Letters","raw_type":"journal-article"},{"id":"pmid:8013879","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8013879","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS microbiology letters","raw_type":"Comparative Study"}],"best_oa_location":{"id":"doi:10.1016/0378-1097(94)90592-4","doi":"https://doi.org/10.1016/0378-1097(94)90592-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/0378-1097(94)90592-4","pdf_url":"https://academic.oup.com/femsle/article-pdf/118/1-2/31/19094003/118-1-2-31.pdf","source":{"id":"https://openalex.org/S34954451","display_name":"FEMS Microbiology Letters","issn_l":"0378-1097","issn":["0378-1097","1574-6968"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS Microbiology Letters","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2603075655","display_name":null,"funder_award_id":"R01-A125631","funder_id":"https://openalex.org/F4320332505","funder_display_name":"U.S. Public Health Service"}],"funders":[{"id":"https://openalex.org/F4320321589","display_name":"Fondation pour la Recherche M\u00e9dicale","ror":"https://ror.org/04w6kn183"},{"id":"https://openalex.org/F4320324195","display_name":"Medical Research Council Canada","ror":"https://ror.org/01gavpb45"},{"id":"https://openalex.org/F4320332505","display_name":"U.S. Public Health Service","ror":"https://ror.org/05xf94514"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2046084467.pdf","grobid_xml":"https://content.openalex.org/works/W2046084467.grobid-xml"},"referenced_works_count":21,"referenced_works":["https://openalex.org/W9214793","https://openalex.org/W621035214","https://openalex.org/W1638888989","https://openalex.org/W1784937739","https://openalex.org/W1853565383","https://openalex.org/W1956829252","https://openalex.org/W1969533035","https://openalex.org/W1980667302","https://openalex.org/W1987603405","https://openalex.org/W2064353733","https://openalex.org/W2080490975","https://openalex.org/W2122821108","https://openalex.org/W2123880134","https://openalex.org/W2128171244","https://openalex.org/W2137016075","https://openalex.org/W2144634347","https://openalex.org/W2162632240","https://openalex.org/W2162684887","https://openalex.org/W2314225431","https://openalex.org/W2320937221","https://openalex.org/W2321415533"],"related_works":["https://openalex.org/W2147158062","https://openalex.org/W166497400","https://openalex.org/W2162684887","https://openalex.org/W2408961121","https://openalex.org/W2061157440","https://openalex.org/W2410321511","https://openalex.org/W2022427396","https://openalex.org/W2034195651","https://openalex.org/W2143255995","https://openalex.org/W7098752313"],"abstract_inverted_index":{"Genomic":[0],"DNA":[1,24],"from":[2,34,39,125],"15":[3],"strains":[4,30,123],"of":[5,66,86,118],"Helicobacter":[6],"mustelae":[7,22,52,88,106,140],"was":[8,55,79,101],"subjected":[9],"to":[10,57,64,109],"pulsed-field":[11],"gel":[12],"electrophoresis":[13],"(PFGE)":[14],"after":[15],"digestion":[16],"with":[17,99],"PacI":[18,73],"and":[19,76,83],"SfiI.":[20],"H.":[21,51,67,87,105,139,147],"genome":[23,53,77,94],"appeared":[25],"very":[26],"similar":[27,61],"in":[28,42,47,62,72,93,116,122,134,146],"all":[29],"examined,":[31],"whether":[32],"isolated":[33],"ferrets":[35,113],"or":[36,38,46],"mink":[37],"animals":[40],"bred":[41],"either":[43],"the":[44,48,126,142],"USA":[45],"UK.":[49],"The":[50],"size":[54,63,78],"estimated":[56],"be":[58],"1.7":[59],"Mb,":[60],"that":[65],"pylori.":[68,148],"A":[69],"minor":[70,91,132],"difference":[71,92],"PFGE":[74,98,135],"pattern":[75,95,136],"observed":[80,102,145],"between":[81,103],"rifampicin-resistant":[82],"rifampicin-susceptible":[84],"derivatives":[85],"F251.":[89],"Another":[90],"based":[96],"on":[97],"SfiI":[100,120],"an":[104,119],"strain":[107],"used":[108],"experimentally":[110],"infect":[111],"four":[112],"which":[114],"resulted":[115],"loss":[117],"site":[121],"obtained":[124],"newly":[127],"infected":[128],"ferrets.":[129],"Thus,":[130],"although":[131],"differences":[133],"were":[137],"noted,":[138],"lacks":[141],"genomic":[143],"diversity":[144]},"counts_by_year":[{"year":2014,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}