{"id":"https://openalex.org/W2045983236","doi":"https://doi.org/10.1016/0041-008x(78)90201-6","title":"Lithium chloride and dilithium carbamyl phosphate: Lithium distribution and toxicity in mice","display_name":"Lithium chloride and dilithium carbamyl phosphate: Lithium distribution and toxicity in mice","publication_year":1978,"publication_date":"1978-05-01","ids":{"openalex":"https://openalex.org/W2045983236","doi":"https://doi.org/10.1016/0041-008x(78)90201-6","mag":"2045983236","pmid":"https://pubmed.ncbi.nlm.nih.gov/675711"},"language":"en","primary_location":{"id":"doi:10.1016/0041-008x(78)90201-6","doi":"https://doi.org/10.1016/0041-008x(78)90201-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0041-008x(78)90201-6","pdf_url":null,"source":{"id":"https://openalex.org/S42307217","display_name":"Toxicology and Applied Pharmacology","issn_l":"0041-008X","issn":["0041-008X","1096-0333"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicology and Applied Pharmacology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089720392","display_name":"Howard M. Jernigan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160606119","display_name":"University of Tennessee Health Science Center","ror":"https://ror.org/0011qv509","country_code":"US","type":"education","lineage":["https://openalex.org/I160606119"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Howard M. Jernigan","raw_affiliation_strings":["Department of Biochemistry, University of Tennessee Center for the Health Sciences, Memphis, Tennessee 38163 USA","Department of Microbiology, University of Tennessee Center for the Health Sciences, Memphis, Tennessee 38163 USA","the Comprehensive Sickle Cell Center, University of Tennessee Center for the Health Sciences, Memphis, Tennessee 38163 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Tennessee Center for the Health Sciences, Memphis, Tennessee 38163 USA","institution_ids":["https://openalex.org/I160606119"]},{"raw_affiliation_string":"Department of Microbiology, University of Tennessee Center for the Health Sciences, Memphis, Tennessee 38163 USA","institution_ids":["https://openalex.org/I160606119"]},{"raw_affiliation_string":"the Comprehensive Sickle Cell Center, University of Tennessee Center for the Health Sciences, Memphis, Tennessee 38163 USA","institution_ids":["https://openalex.org/I160606119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076167425","display_name":"Gordon D. Schrank","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160606119","display_name":"University of Tennessee Health Science Center","ror":"https://ror.org/0011qv509","country_code":"US","type":"education","lineage":["https://openalex.org/I160606119"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gordon D. Schrank","raw_affiliation_strings":["Department of Biochemistry, University of Tennessee Center for the Health Sciences, Memphis, Tennessee 38163 USA","Department of Microbiology, University of Tennessee Center for the Health Sciences, Memphis, Tennessee 38163 USA","the Comprehensive Sickle Cell Center, University of Tennessee Center for the Health Sciences, Memphis, Tennessee 38163 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Tennessee Center for the Health Sciences, Memphis, Tennessee 38163 USA","institution_ids":["https://openalex.org/I160606119"]},{"raw_affiliation_string":"Department of Microbiology, University of Tennessee Center for the Health Sciences, Memphis, Tennessee 38163 USA","institution_ids":["https://openalex.org/I160606119"]},{"raw_affiliation_string":"the Comprehensive Sickle Cell Center, University of Tennessee Center for the Health Sciences, Memphis, Tennessee 38163 USA","institution_ids":["https://openalex.org/I160606119"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090045705","display_name":"Lorraine M. Kraus","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160606119","display_name":"University of Tennessee Health Science Center","ror":"https://ror.org/0011qv509","country_code":"US","type":"education","lineage":["https://openalex.org/I160606119"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Lorraine M. Kraus","raw_affiliation_strings":["Department of Biochemistry, University of Tennessee Center for the Health Sciences, Memphis, Tennessee 38163 USA","Department of Microbiology, University of Tennessee Center for the Health Sciences, Memphis, Tennessee 38163 USA","the Comprehensive Sickle Cell Center, University of Tennessee Center for the Health Sciences, Memphis, Tennessee 38163 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Tennessee Center for the Health Sciences, Memphis, Tennessee 38163 USA","institution_ids":["https://openalex.org/I160606119"]},{"raw_affiliation_string":"Department of Microbiology, University of Tennessee Center for the Health Sciences, Memphis, Tennessee 38163 USA","institution_ids":["https://openalex.org/I160606119"]},{"raw_affiliation_string":"the Comprehensive Sickle Cell Center, University of Tennessee Center for the Health Sciences, Memphis, Tennessee 38163 USA","institution_ids":["https://openalex.org/I160606119"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5090045705"],"corresponding_institution_ids":["https://openalex.org/I160606119"],"apc_list":{"value":4200,"currency":"USD","value_usd":4200},"apc_paid":null,"fwci":0.4305,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.58346928,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"44","issue":"2","first_page":"413","last_page":"421"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":0.18299999833106995,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":0.18299999833106995,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11635","display_name":"Poisoning and overdose treatments","score":0.15150000154972076,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12286","display_name":"Erythrocyte Function and Pathophysiology","score":0.08630000054836273,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lithium-chloride","display_name":"lithium chloride","score":0.9819999933242798},{"id":"https://openalex.org/keywords/lithium-toxicity","display_name":"lithium toxicity","score":0.9200000166893005},{"id":"https://openalex.org/keywords/antisickling-agents","display_name":"antisickling agents","score":0.8880000114440918},{"id":"https://openalex.org/keywords/carbamoyl-phosphate","display_name":"carbamoyl phosphate","score":0.578000009059906}],"concepts":[{"id":"https://openalex.org/C2908748535","wikidata":"https://www.wikidata.org/wiki/Q424409","display_name":"Carbamyl Phosphate","level":3,"score":0.877882719039917},{"id":"https://openalex.org/C2775951159","wikidata":"https://www.wikidata.org/wiki/Q1189242","display_name":"Dilithium","level":4,"score":0.8156522512435913},{"id":"https://openalex.org/C2778541603","wikidata":"https://www.wikidata.org/wiki/Q152763","display_name":"Lithium (medication)","level":2,"score":0.747541606426239},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7078737020492554},{"id":"https://openalex.org/C2777132085","wikidata":"https://www.wikidata.org/wiki/Q46220103","display_name":"Phosphate","level":2,"score":0.593935489654541},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.5763144493103027},{"id":"https://openalex.org/C2780990938","wikidata":"https://www.wikidata.org/wiki/Q422930","display_name":"Lithium chloride","level":2,"score":0.5576924085617065},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.49434971809387207},{"id":"https://openalex.org/C2778917026","wikidata":"https://www.wikidata.org/wiki/Q43041","display_name":"Hemoglobin","level":2,"score":0.4196024537086487},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.41057464480400085},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3358990550041199},{"id":"https://openalex.org/C179104552","wikidata":"https://www.wikidata.org/wiki/Q11165","display_name":"Inorganic chemistry","level":1,"score":0.20043039321899414},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1869933009147644},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.10035595297813416},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.07921302318572998},{"id":"https://openalex.org/C145148216","wikidata":"https://www.wikidata.org/wiki/Q36496","display_name":"Ion","level":2,"score":0.06199875473976135},{"id":"https://openalex.org/C118629725","wikidata":"https://www.wikidata.org/wiki/Q2686738","display_name":"Deprotonation","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002219","descriptor_name":"Carbamates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002221","descriptor_name":"Carbamyl Phosphate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002221","descriptor_name":"Carbamyl Phosphate","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006400","descriptor_name":"Hematocrit","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006454","descriptor_name":"Hemoglobins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007958","descriptor_name":"Leukocyte Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008094","descriptor_name":"Lithium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008094","descriptor_name":"Lithium","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014018","descriptor_name":"Tissue Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0041-008x(78)90201-6","doi":"https://doi.org/10.1016/0041-008x(78)90201-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0041-008x(78)90201-6","pdf_url":null,"source":{"id":"https://openalex.org/S42307217","display_name":"Toxicology and Applied Pharmacology","issn_l":"0041-008X","issn":["0041-008X","1096-0333"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicology and Applied Pharmacology","raw_type":"journal-article"},{"id":"pmid:675711","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/675711","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicology and applied pharmacology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W206293563","https://openalex.org/W1950371127","https://openalex.org/W1984697903","https://openalex.org/W2006171391","https://openalex.org/W2009623237","https://openalex.org/W2015694963","https://openalex.org/W2134358598","https://openalex.org/W2401027282","https://openalex.org/W2417785655","https://openalex.org/W2431118567","https://openalex.org/W2460134640"],"related_works":["https://openalex.org/W2088342429","https://openalex.org/W2495626248","https://openalex.org/W2098062640","https://openalex.org/W2061328313","https://openalex.org/W2043416705","https://openalex.org/W2156562843","https://openalex.org/W2157700932","https://openalex.org/W258477192","https://openalex.org/W1983935786","https://openalex.org/W2312306285"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}