{"id":"https://openalex.org/W2045919099","doi":"https://doi.org/10.1056/nejm199102143240706","title":"Common Solid Tumors of Childhood","display_name":"Common Solid Tumors of Childhood","publication_year":1991,"publication_date":"1991-02-14","ids":{"openalex":"https://openalex.org/W2045919099","doi":"https://doi.org/10.1056/nejm199102143240706","mag":"2045919099","pmid":"https://pubmed.ncbi.nlm.nih.gov/1988832"},"language":"en","primary_location":{"id":"doi:10.1056/nejm199102143240706","doi":"https://doi.org/10.1056/nejm199102143240706","is_oa":false,"landing_page_url":"https://doi.org/10.1056/nejm199102143240706","pdf_url":null,"source":{"id":"https://openalex.org/S62468778","display_name":"New England Journal of Medicine","issn_l":"0028-4793","issn":["0028-4793","0096-6762","1533-4406","2331-4710"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320239","host_organization_name":"Massachusetts Medical Society","host_organization_lineage":["https://openalex.org/P4310320239"],"host_organization_lineage_names":["Massachusetts Medical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"New England Journal of Medicine","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001135712","display_name":"WM Crist","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1313298211","display_name":"St. Jude Children's Research Hospital","ror":"https://ror.org/02r3e0967","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1313298211","https://openalex.org/I2802152183"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William M. Crist","raw_affiliation_strings":["Department of Hematology-Oncology, St. Jude Children's Research Hospital, Memphis, TN 38101","Departments of Hematology\u2014Oncology, St. Jude Children's Research Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology-Oncology, St. Jude Children's Research Hospital, Memphis, TN 38101","institution_ids":["https://openalex.org/I1313298211"]},{"raw_affiliation_string":"Departments of Hematology\u2014Oncology, St. Jude Children's Research Hospital","institution_ids":["https://openalex.org/I1313298211"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042463331","display_name":"Larry E. Kun","orcid":"https://orcid.org/0000-0003-0386-419X","observed_orcids":["https://orcid.org/0000-0003-0386-419X"]},"institutions":[{"id":"https://openalex.org/I1313298211","display_name":"St. Jude Children's Research Hospital","ror":"https://ror.org/02r3e0967","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1313298211","https://openalex.org/I2802152183"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Larry E. Kun","raw_affiliation_strings":["Radiation Oncology, St. Jude Children's Research Hospital","Section of Radiation Oncology, College of Medicine, University of Tennessee, both in Memphis. Address reprint requests to Dr. Crist at St. Jude Children's Research Hospital, P.O. Box 318, Memphis, TN 38101"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiation Oncology, St. Jude Children's Research Hospital","institution_ids":["https://openalex.org/I1313298211"]},{"raw_affiliation_string":"Section of Radiation Oncology, College of Medicine, University of Tennessee, both in Memphis. Address reprint requests to Dr. Crist at St. Jude Children's Research Hospital, P.O. Box 318, Memphis, TN 38101","institution_ids":["https://openalex.org/I1313298211"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1313298211"],"apc_list":null,"apc_paid":null,"fwci":3.5994,"has_fulltext":false,"cited_by_count":205,"citation_normalized_percentile":{"value":0.95689655,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"324","issue":"7","first_page":"461","last_page":"471"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10950","display_name":"Acute Lymphoblastic Leukemia research","score":0.40059998631477356,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10950","display_name":"Acute Lymphoblastic Leukemia research","score":0.40059998631477356,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.2563000023365021,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11141","display_name":"Childhood Cancer Survivors' Quality of Life","score":0.08410000056028366,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pediatric-solid-tumors","display_name":"pediatric solid tumors","score":0.8529999852180481},{"id":"https://openalex.org/keywords/pediatric-cancer","display_name":"childhood cancer","score":0.9369999766349792},{"id":"https://openalex.org/keywords/wilms-tumor","display_name":"Wilms tumor","score":0.9129999876022339},{"id":"https://openalex.org/keywords/dactinomycin","display_name":"actinomycin D","score":0.9789999723434448},{"id":"https://openalex.org/keywords/histological-subtypes","display_name":"histological subtypes","score":0.8159999847412109},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.949999988079071},{"id":"https://openalex.org/keywords/cancer-management","display_name":"cancer management","score":0.4699999988079071},{"id":"https://openalex.org/keywords/cure-rate","display_name":"cure rate","score":0.5210000276565552}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9191250205039978},{"id":"https://openalex.org/C2992894027","wikidata":"https://www.wikidata.org/wiki/Q5097977","display_name":"Childhood cancer","level":3,"score":0.6360484957695007},{"id":"https://openalex.org/C2993640289","wikidata":"https://www.wikidata.org/wiki/Q1216998","display_name":"Solid tumor","level":3,"score":0.5585271120071411},{"id":"https://openalex.org/C2775999222","wikidata":"https://www.wikidata.org/wiki/Q756289","display_name":"Wilms' tumor","level":2,"score":0.5539254546165466},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4717743396759033},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.46327659487724304},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3577428162097931},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.31091073155403137},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.279263436794281}],"mesh":[{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1056/nejm199102143240706","doi":"https://doi.org/10.1056/nejm199102143240706","is_oa":false,"landing_page_url":"https://doi.org/10.1056/nejm199102143240706","pdf_url":null,"source":{"id":"https://openalex.org/S62468778","display_name":"New England Journal of Medicine","issn_l":"0028-4793","issn":["0028-4793","0096-6762","1533-4406","2331-4710"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320239","host_organization_name":"Massachusetts Medical Society","host_organization_lineage":["https://openalex.org/P4310320239"],"host_organization_lineage_names":["Massachusetts Medical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"New England Journal of Medicine","raw_type":"journal-article"},{"id":"pmid:1988832","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1988832","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The New England journal of medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5145123177","display_name":"Studies of Childhood Solid Tumors","funder_award_id":"P01CA023099","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000904664","display_name":"Cancer Center Support Grant (CCSG)","funder_award_id":"P30CA021765","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":150,"referenced_works":["https://openalex.org/W56550348","https://openalex.org/W584851871","https://openalex.org/W1480878209","https://openalex.org/W1543422669","https://openalex.org/W1556555576","https://openalex.org/W1570290805","https://openalex.org/W1631358477","https://openalex.org/W1750407963","https://openalex.org/W1796977749","https://openalex.org/W1797236870","https://openalex.org/W1827235876","https://openalex.org/W1860006956","https://openalex.org/W1863005346","https://openalex.org/W1867002980","https://openalex.org/W1893545268","https://openalex.org/W1897723143","https://openalex.org/W1910167124","https://openalex.org/W1916718854","https://openalex.org/W1920335633","https://openalex.org/W1937500088","https://openalex.org/W1947312736","https://openalex.org/W1947572199","https://openalex.org/W1964619416","https://openalex.org/W1966155043","https://openalex.org/W1966748263","https://openalex.org/W1968618193","https://openalex.org/W1971400303","https://openalex.org/W1973158710","https://openalex.org/W1977442544","https://openalex.org/W1977826988","https://openalex.org/W1980668412","https://openalex.org/W1982343420","https://openalex.org/W1982361487","https://openalex.org/W1982933686","https://openalex.org/W1982939999","https://openalex.org/W1983322464","https://openalex.org/W1986538121","https://openalex.org/W1987577319","https://openalex.org/W1989752636","https://openalex.org/W1990298357","https://openalex.org/W1993610674","https://openalex.org/W1993947788","https://openalex.org/W1993951035","https://openalex.org/W1995822744","https://openalex.org/W1995958749","https://openalex.org/W1996465274","https://openalex.org/W1997680695","https://openalex.org/W2001258296","https://openalex.org/W2002032362","https://openalex.org/W2005542290","https://openalex.org/W2006110310","https://openalex.org/W2009263545","https://openalex.org/W2009622908","https://openalex.org/W2009907283","https://openalex.org/W2011544497","https://openalex.org/W2013735685","https://openalex.org/W2013863113","https://openalex.org/W2015337698","https://openalex.org/W2016803105","https://openalex.org/W2022391231","https://openalex.org/W2023905569","https://openalex.org/W2024280594","https://openalex.org/W2026308299","https://openalex.org/W2030086980","https://openalex.org/W2032087773","https://openalex.org/W2032631136","https://openalex.org/W2032994424","https://openalex.org/W2033321609","https://openalex.org/W2034440981","https://openalex.org/W2039465905","https://openalex.org/W2041212687","https://openalex.org/W2041712974","https://openalex.org/W2042771387","https://openalex.org/W2045553573","https://openalex.org/W2046432077","https://openalex.org/W2046556570","https://openalex.org/W2048202605","https://openalex.org/W2049139884","https://openalex.org/W2049991672","https://openalex.org/W2050997721","https://openalex.org/W2051964401","https://openalex.org/W2052207224","https://openalex.org/W2052421061","https://openalex.org/W2052557404","https://openalex.org/W2053309800","https://openalex.org/W2058454398","https://openalex.org/W2058743845","https://openalex.org/W2060329089","https://openalex.org/W2062315648","https://openalex.org/W2063126195","https://openalex.org/W2063759313","https://openalex.org/W2064618550","https://openalex.org/W2066328877","https://openalex.org/W2066455112","https://openalex.org/W2067708781","https://openalex.org/W2068074614","https://openalex.org/W2068402552","https://openalex.org/W2072570789","https://openalex.org/W2079450481","https://openalex.org/W2080016765","https://openalex.org/W2081168848","https://openalex.org/W2081220665","https://openalex.org/W2081541249","https://openalex.org/W2081924229","https://openalex.org/W2082571806","https://openalex.org/W2082852817","https://openalex.org/W2083378506","https://openalex.org/W2084773583","https://openalex.org/W2087440008","https://openalex.org/W2090250559","https://openalex.org/W2090433173","https://openalex.org/W2095440568","https://openalex.org/W2102628178","https://openalex.org/W2104996683","https://openalex.org/W2110737893","https://openalex.org/W2114151547","https://openalex.org/W2123303774","https://openalex.org/W2126310141","https://openalex.org/W2130357711","https://openalex.org/W2130753104","https://openalex.org/W2132342943","https://openalex.org/W2136594231","https://openalex.org/W2139478740","https://openalex.org/W2141347205","https://openalex.org/W2148069086","https://openalex.org/W2157323563","https://openalex.org/W2158028846","https://openalex.org/W2164650822","https://openalex.org/W2167563627","https://openalex.org/W2171532038","https://openalex.org/W2180449943","https://openalex.org/W2206624148","https://openalex.org/W2229636701","https://openalex.org/W2238637976","https://openalex.org/W2239269703","https://openalex.org/W2259337081","https://openalex.org/W2264275593","https://openalex.org/W2315401129","https://openalex.org/W2317833459","https://openalex.org/W2327625380","https://openalex.org/W2329218644","https://openalex.org/W2409640176","https://openalex.org/W2414340841","https://openalex.org/W2416870126","https://openalex.org/W2439611434","https://openalex.org/W2491874531","https://openalex.org/W2495015930","https://openalex.org/W4238438613","https://openalex.org/W4247040978","https://openalex.org/W6838243271"],"related_works":["https://openalex.org/W2497766270","https://openalex.org/W2112695059","https://openalex.org/W4388156965","https://openalex.org/W4231595129","https://openalex.org/W2904937498","https://openalex.org/W2116539772","https://openalex.org/W4388115216","https://openalex.org/W196541515","https://openalex.org/W2409119848","https://openalex.org/W1964095526"],"abstract_inverted_index":{"CHILDHOOD":[0],"cancer":[1],"is":[2,10],"rare":[3],"in":[4,18,29,49,67],"the":[5,11,50,59,68],"United":[6],"States,":[7],"but":[8],"it":[9],"leading":[12],"cause":[13],"of":[14,27,52,61,73],"death":[15],"from":[16],"disease":[17],"children":[19,30],"1":[20],"to":[21,65],"15":[22],"years":[23],"old.1":[24],"The":[25],"majority":[26],"cancers":[28],"are":[31,40],"malignant":[32],"solid":[33,76],"tumors,":[34],"and":[35,96],"about":[36],"4000":[37],"new":[38,86],"cases":[39],"diagnosed":[41],"each":[42],"year.1":[43],"Enormous":[44],"strides":[45],"have":[46,78,93],"been":[47,94],"made":[48],"management":[51],"these":[53],"neoplasms":[54],"since":[55],"Farber":[56],"first":[57],"demonstrated":[58],"sensitivity":[60],"metastatic":[62],"Wilms'":[63],"tumor":[64],"dactinomycin":[66],"mid-1960s.2":[69],"For":[70],"example,":[71],"rates":[72],"cure":[74],"for":[75,91],"tumors":[77],"increased":[79],"by":[80],"as":[81,83],"much":[82],"50":[84],"percent;":[85],"histologic":[87],"subtypes":[88],"with":[89],"implications":[90],"prognosis":[92],"identified":[95],"incorporated":[97],"into":[98],"systems":[99],".":[100,101,102]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}
