{"id":"https://openalex.org/W2045910150","doi":"https://doi.org/10.1093/jat/13.2.105","title":"Determination of Sulfide in Brain Tissue by Gas Dialysis/Ion Chromatography: Postmortem Studies and Two Case Reports","display_name":"Determination of Sulfide in Brain Tissue by Gas Dialysis/Ion Chromatography: Postmortem Studies and Two Case Reports","publication_year":1989,"publication_date":"1989-03-01","ids":{"openalex":"https://openalex.org/W2045910150","doi":"https://doi.org/10.1093/jat/13.2.105","mag":"2045910150","pmid":"https://pubmed.ncbi.nlm.nih.gov/2733387"},"language":"en","primary_location":{"id":"doi:10.1093/jat/13.2.105","doi":"https://doi.org/10.1093/jat/13.2.105","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jat/13.2.105","pdf_url":null,"source":{"id":"https://openalex.org/S140972820","display_name":"Journal of Analytical Toxicology","issn_l":"0146-4760","issn":["0146-4760","1945-2403"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Analytical Toxicology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071140458","display_name":"Lorne R. Goodwin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"L. R. Goodwin","raw_affiliation_strings":["Alberta Environmental Centre, Vegreville, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alberta Environmental Centre, Vegreville, Canada","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053988916","display_name":"Donna M. Francom","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D. Francom","raw_affiliation_strings":["Alberta Environmental Centre, Vegreville, Alberta, Canada T0B 4L0"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alberta Environmental Centre, Vegreville, Alberta, Canada T0B 4L0","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083724714","display_name":"Fred P. Dieken","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F. P. Dieken","raw_affiliation_strings":["Alberta Environmental Centre, Vegreville, Alberta, Canada T0B 4L0"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alberta Environmental Centre, Vegreville, Alberta, Canada T0B 4L0","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000294024","display_name":"J.D. Taylor","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. D. Taylor","raw_affiliation_strings":["Alberta Environmental Centre, Vegreville, Alberta, Canada T0B 4L0"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alberta Environmental Centre, Vegreville, Alberta, Canada T0B 4L0","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077883405","display_name":"Marcus W. Warenycia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"M. W. Warenycia","raw_affiliation_strings":["Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada T6G 2H7"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada T6G 2H7","institution_ids":["https://openalex.org/I154425047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111744463","display_name":"R. J. Reiffenstein","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"R. J. Reiffenstein","raw_affiliation_strings":["Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada T6G 2H7"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada T6G 2H7","institution_ids":["https://openalex.org/I154425047"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110294102","display_name":"G Dowling","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210111592","display_name":"Office of the Chief Medical Examiner","ror":"https://ror.org/01zdmh905","country_code":"CA","type":"government","lineage":["https://openalex.org/I4210111592"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"G. Dowling","raw_affiliation_strings":["Office of the Chief Medical Examiner, Edmonton, Alberta, Canada T6H 5R8"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Office of the Chief Medical Examiner, Edmonton, Alberta, Canada T6H 5R8","institution_ids":["https://openalex.org/I4210111592"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5071140458"],"corresponding_institution_ids":[],"apc_list":{"value":4823,"currency":"USD","value_usd":4823},"apc_paid":null,"fwci":2.9858,"has_fulltext":false,"cited_by_count":318,"citation_normalized_percentile":{"value":0.88859764,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"13","issue":"2","first_page":"105","last_page":"109"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10800","display_name":"Forensic Toxicology and Drug Analysis","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10800","display_name":"Forensic Toxicology and Drug Analysis","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11481","display_name":"Sulfur Compounds in Biology","score":0.006200000178068876,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10908","display_name":"Analytical Chemistry and Chromatography","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hydrogen-sulfide","display_name":"hydrogen sulfide","score":0.7960000038146973},{"id":"https://openalex.org/keywords/ion-chromatography","display_name":"ion chromatography","score":0.8970000147819519},{"id":"https://openalex.org/keywords/electrochemical-detection","display_name":"electrochemical detection","score":0.9210000038146973},{"id":"https://openalex.org/keywords/post-mortem-analysis","display_name":"post-mortem analysis","score":0.6150000095367432},{"id":"https://openalex.org/keywords/rat-brain","display_name":"rat brain","score":0.7099999785423279},{"id":"https://openalex.org/keywords/human-brain","display_name":"human brain","score":0.9330000281333923}],"concepts":[{"id":"https://openalex.org/C2780564542","wikidata":"https://www.wikidata.org/wiki/Q170591","display_name":"Hydrogen sulfide","level":3,"score":0.7549495697021484},{"id":"https://openalex.org/C2780596425","wikidata":"https://www.wikidata.org/wiki/Q221205","display_name":"Sulfide","level":2,"score":0.7146070003509521},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.684861421585083},{"id":"https://openalex.org/C2779978075","wikidata":"https://www.wikidata.org/wiki/Q202301","display_name":"Dialysis","level":2,"score":0.5219725370407104},{"id":"https://openalex.org/C2776954882","wikidata":"https://www.wikidata.org/wiki/Q840343","display_name":"Inhalation","level":2,"score":0.4813012182712555},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.47538697719573975},{"id":"https://openalex.org/C123460561","wikidata":"https://www.wikidata.org/wiki/Q677065","display_name":"Gas chromatography","level":2,"score":0.4412803053855896},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.20396706461906433},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1812620759010315},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1391943395137787},{"id":"https://openalex.org/C518881349","wikidata":"https://www.wikidata.org/wiki/Q682","display_name":"Sulfur","level":2,"score":0.1257193386554718},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.08938124775886536}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001923","descriptor_name":"Brain Chemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001933","descriptor_name":"Brain Stem","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D002845","descriptor_name":"Chromatography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D003956","descriptor_name":"Dialysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D004563","descriptor_name":"Electrochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006862","descriptor_name":"Hydrogen Sulfide","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D006862","descriptor_name":"Hydrogen Sulfide","qualifier_ui":"Q000506","qualifier_name":"poisoning","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011919","descriptor_name":"Rats, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/jat/13.2.105","doi":"https://doi.org/10.1093/jat/13.2.105","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jat/13.2.105","pdf_url":null,"source":{"id":"https://openalex.org/S140972820","display_name":"Journal of Analytical Toxicology","issn_l":"0146-4760","issn":["0146-4760","1945-2403"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Analytical Toxicology","raw_type":"journal-article"},{"id":"pmid:2733387","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2733387","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of analytical toxicology","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1536789647","https://openalex.org/W1599070454","https://openalex.org/W1983880621","https://openalex.org/W1999077696","https://openalex.org/W2005553811","https://openalex.org/W2023211325","https://openalex.org/W2032719828","https://openalex.org/W2065658758","https://openalex.org/W2078288194","https://openalex.org/W2081460287","https://openalex.org/W2088739224","https://openalex.org/W2318165501"],"related_works":["https://openalex.org/W1995323993","https://openalex.org/W1592009867","https://openalex.org/W3087933619","https://openalex.org/W1602026215","https://openalex.org/W2029730105","https://openalex.org/W2281336026","https://openalex.org/W3022094883","https://openalex.org/W2038275943","https://openalex.org/W2034608258","https://openalex.org/W1971373316"],"abstract_inverted_index":{"An":[0],"analytical":[1],"method":[2,121],"for":[3],"the":[4,56,99],"determination":[5],"of":[6,44,49,58,61,77,111],"sulfide":[7,33,62,78,87,114,128],"in":[8,63,130],"human":[9,67,112],"and":[10,23,66],"rat":[11,65,83],"brain":[12,32,68,75,84],"is":[13],"described.":[14],"It":[15],"utilizes":[16],"a":[17],"continuous":[18],"flow":[19],"gas":[20],"dialysis":[21],"pretreatment":[22],"quantitation":[24],"by":[25,41],"ion":[26],"chromatography":[27],"with":[28],"electrochemical":[29],"detection.":[30],"Rat":[31],"levels":[34,60,76,88,129],"were":[35],"reliably":[36,92],"measured":[37],"after":[38,79,96],"fatal":[39],"intoxication":[40],"intraperitoneal":[42],"injection":[43],"NaHS.":[45],"By":[46],"expeditious":[47],"analysis":[48],"samples":[50],"it":[51],"was":[52,122],"possible":[53],"to":[54,72,124],"demonstrate":[55],"presence":[57],"endogenous":[59],"both":[64,131],"as":[69,71],"well":[70],"measure":[73,125],"elevated":[74,86,127],"intoxication.":[80],"In":[81],"postmortem":[82],"tissue,":[85],"could":[89],"still":[90],"be":[91],"demonstrated":[93],"96":[94],"h":[95],"death":[97],"if":[98],"bodies":[100],"had":[101],"been":[102],"refrigerated":[103],"at":[104],"4":[105],"degrees":[106],"C.":[107],"Two":[108],"case":[109],"studies":[110],"hydrogen":[113],"inhalation":[115],"fatalities":[116],"are":[117],"presented.":[118],"The":[119],"described":[120],"able":[123],"significantly":[126],"cases.":[132]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":16},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":17},{"year":2021,"cited_by_count":18},{"year":2020,"cited_by_count":18},{"year":2019,"cited_by_count":12},{"year":2018,"cited_by_count":19},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":13},{"year":2015,"cited_by_count":15},{"year":2014,"cited_by_count":18},{"year":2013,"cited_by_count":21},{"year":2012,"cited_by_count":16}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}