{"id":"https://openalex.org/W2045890653","doi":"https://doi.org/10.1103/physreve.57.6982","title":"Impedance analysis of fibroblastic cell layers measured by electric cell-substrate impedance sensing","display_name":"Impedance analysis of fibroblastic cell layers measured by electric cell-substrate impedance sensing","publication_year":1998,"publication_date":"1998-06-01","ids":{"openalex":"https://openalex.org/W2045890653","doi":"https://doi.org/10.1103/physreve.57.6982","mag":"2045890653"},"language":"en","primary_location":{"id":"doi:10.1103/physreve.57.6982","doi":"https://doi.org/10.1103/physreve.57.6982","is_oa":false,"landing_page_url":"https://doi.org/10.1103/physreve.57.6982","pdf_url":null,"source":{"id":"https://openalex.org/S4210224030","display_name":"Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics","issn_l":"1063-651X","issn":["1063-651X","1095-3787","1538-4519"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physical Review E","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077671722","display_name":"Chun\u2010Min Lo","orcid":"https://orcid.org/0000-0003-4382-4512","observed_orcids":["https://orcid.org/0000-0003-4382-4512"]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Chun-Min Lo","raw_affiliation_strings":["Medical Research Council Group in Periodontal Physiology, University of Toronto, Toronto, Ontario, Canada M5S 1A8"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Research Council Group in Periodontal Physiology, University of Toronto, Toronto, Ontario, Canada M5S 1A8","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113530930","display_name":"Jack Ferrier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jack Ferrier","raw_affiliation_strings":["Medical Research Council Group in Periodontal Physiology, University of Toronto, Toronto, Ontario, Canada M5S 1A8"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Research Council Group in Periodontal Physiology, University of Toronto, Toronto, Ontario, Canada M5S 1A8","institution_ids":["https://openalex.org/I185261750"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I185261750"],"apc_list":null,"apc_paid":null,"fwci":0.1617,"has_fulltext":false,"cited_by_count":66,"citation_normalized_percentile":{"value":0.40515982,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"57","issue":"6","first_page":"6982","last_page":"6987"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9110999703407288,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9110999703407288,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11434","display_name":"Electrochemical Analysis and Applications","score":0.019500000402331352,"subfield":{"id":"https://openalex.org/subfields/1603","display_name":"Electrochemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11778","display_name":"Electrical and Bioimpedance Tomography","score":0.013100000098347664,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/electric-cell-substrate-impedance-sensing","display_name":"electric cell-substrate impedance sensing","score":0.9350000023841858},{"id":"https://openalex.org/keywords/fibroblasts","display_name":"fibroblasts","score":0.7639999985694885},{"id":"https://openalex.org/keywords/cell-morphology","display_name":"cell morphology","score":0.4699999988079071},{"id":"https://openalex.org/keywords/impedance-model","display_name":"impedance model","score":0.7250000238418579},{"id":"https://openalex.org/keywords/gold-electrode-surfaces","display_name":"gold electrode surfaces","score":0.5270000100135803},{"id":"https://openalex.org/keywords/gingival-fibroblasts","display_name":"gingival fibroblasts","score":0.9399999976158142},{"id":"https://openalex.org/keywords/temperature-dependence","display_name":"temperature dependence","score":0.6480000019073486},{"id":"https://openalex.org/keywords/cell-adhesion","display_name":"cell adhesion","score":0.492000013589859}],"concepts":[{"id":"https://openalex.org/C17829176","wikidata":"https://www.wikidata.org/wiki/Q179043","display_name":"Electrical impedance","level":2,"score":0.7224795818328857},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.6806147694587708},{"id":"https://openalex.org/C2777289219","wikidata":"https://www.wikidata.org/wiki/Q7632154","display_name":"Substrate (aquarium)","level":2,"score":0.6444168090820312},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6263453960418701},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.46165311336517334},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.3903866410255432},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.38713741302490234},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3586217164993286},{"id":"https://openalex.org/C113196181","wikidata":"https://www.wikidata.org/wiki/Q485223","display_name":"Analytical Chemistry (journal)","level":2,"score":0.34044045209884644},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.3209412395954132},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.27500879764556885},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.16899296641349792},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.16801247000694275},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.10683548450469971},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1103/physreve.57.6982","doi":"https://doi.org/10.1103/physreve.57.6982","is_oa":false,"landing_page_url":"https://doi.org/10.1103/physreve.57.6982","pdf_url":null,"source":{"id":"https://openalex.org/S4210224030","display_name":"Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics","issn_l":"1063-651X","issn":["1063-651X","1095-3787","1538-4519"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physical Review E","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1559994288","https://openalex.org/W1806064940","https://openalex.org/W1995797294","https://openalex.org/W2038628992","https://openalex.org/W2082072590","https://openalex.org/W2082538362","https://openalex.org/W2089289309","https://openalex.org/W2103725270","https://openalex.org/W2144454908","https://openalex.org/W2148329395","https://openalex.org/W4231901431"],"related_works":["https://openalex.org/W2003017740","https://openalex.org/W2073538978","https://openalex.org/W1992241486","https://openalex.org/W2144454908","https://openalex.org/W1978332461","https://openalex.org/W2142914668","https://openalex.org/W205336357","https://openalex.org/W4400198679","https://openalex.org/W2014140537","https://openalex.org/W2296013725"],"abstract_inverted_index":{"Impedance":[0],"measurements":[1],"of":[2,62,74,107,123,132],"cell":[3,46,78,143],"layers":[4,79],"cultured":[5],"on":[6],"gold":[7],"electrode":[8],"surfaces":[9],"obtained":[10,102],"by":[11],"electric":[12,39],"cell-substrate":[13,24,121],"impedance":[14,61,75,100],"sensing":[15],"provide":[16],"morphological":[17],"information":[18],"such":[19],"as":[20],"junctional":[21],"resistance":[22],"and":[23,37,48,135,145,150],"separation.":[25],"Previously,":[26],"a":[27,34,111],"model":[28,73],"that":[29,31,38,109],"assumes":[30],"cells":[32],"have":[33],"disklike":[35],"shape":[36,82],"currents":[40],"flow":[41],"radially":[42],"underneath":[43],"the":[44,51,60,63,96,119,138],"ventral":[45,142],"surface":[47,144],"then":[49],"through":[50],"paracellular":[52],"space":[53],"has":[54],"been":[55],"used":[56],"to":[57],"theoretically":[58],"calculate":[59],"cell-covered":[64],"electrode.":[65],"In":[66,115],"this":[67],"paper":[68],"we":[69,98,117],"propose":[70],"an":[71],"extended":[72],"analysis":[76],"for":[77,89],"where":[80],"cellular":[81],"is":[83,86],"rectangular.":[84],"This":[85],"especially":[87],"appropriate":[88],"normal":[90],"fibroblasts":[91,108,126],"in":[92],"culture.":[93],"To":[94],"verify":[95],"model,":[97],"analyze":[99],"data":[101],"from":[103],"four":[104],"different":[105,128],"kinds":[106],"display":[110],"long":[112],"rectangular":[113],"shape.":[114],"addition,":[116],"measure":[118],"average":[120,139],"separation":[122,140],"human":[124],"gingival":[125],"at":[127],"temperatures.":[129],"At":[130],"temperatures":[131],"37,":[133],"22,":[134],"4":[136],"\\ifmmode^\\circ\\else\\textdegree\\fi{}C,":[137],"between":[141],"substratum":[146],"are":[147],"46,":[148],"55,":[149],"89":[151],"nm,":[152],"respectively.":[153]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}