{"id":"https://openalex.org/W2045870171","doi":"https://doi.org/10.1007/bf02898017","title":"Effect of Estradiol on Heme Biosynthetic Pathway in Lead-Poisoned Rabbits","display_name":"Effect of Estradiol on Heme Biosynthetic Pathway in Lead-Poisoned Rabbits","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W2045870171","doi":"https://doi.org/10.1007/bf02898017","mag":"2045870171","pmid":"https://pubmed.ncbi.nlm.nih.gov/21432356","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2723452"},"language":"en","primary_location":{"id":"doi:10.1007/bf02898017","doi":"https://doi.org/10.1007/bf02898017","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02898017","pdf_url":null,"source":{"id":"https://openalex.org/S110451752","display_name":"Environmental Health and Preventive Medicine","issn_l":"1342-078X","issn":["1342-078X","1347-4715"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental Health and Preventive Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://environhealthprevmed.biomedcentral.com/counter/pdf/10.1007/BF02898017","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113611550","display_name":"Shoko Ohmori","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Shoko Ohmori","raw_affiliation_strings":["Department of Preventive and Environmental Medicine, Graduate School of Medical and Pharmaceutical Sciences, Kumamoto University, 1-1-1, Honjo, 860-8556, Kumamoto, Japan, s-ohmori@kumamoto-u.ac.jp","Department of Preventive and Environmental Medicine, Graduate School of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Preventive and Environmental Medicine, Graduate School of Medical and Pharmaceutical Sciences, Kumamoto University, 1-1-1, Honjo, 860-8556, Kumamoto, Japan, s-ohmori@kumamoto-u.ac.jp","institution_ids":["https://openalex.org/I96036126"]},{"raw_affiliation_string":"Department of Preventive and Environmental Medicine, Graduate School of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan,","institution_ids":["https://openalex.org/I96036126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111609550","display_name":"Koichi Harada","orcid":"https://orcid.org/0009-0009-5453-6699","observed_orcids":["https://orcid.org/0009-0009-5453-6699"]},"institutions":[{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Koichi Harada","raw_affiliation_strings":["Department of Microbiology and Environmental Chemistry School of Health Science, Kumamoto University, Kumamoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Environmental Chemistry School of Health Science, Kumamoto University, Kumamoto, Japan","institution_ids":["https://openalex.org/I96036126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111741370","display_name":"Chang Wei","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Chang Nian Wei","raw_affiliation_strings":["Center for Policy Studies, Kumamoto University, Kumamoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Policy Studies, Kumamoto University, Kumamoto, Japan","institution_ids":["https://openalex.org/I96036126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040737644","display_name":"Qingjum Wei","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Qingjum Wei","raw_affiliation_strings":["Department of Preventive and Environmental Medicine, Graduate School of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Preventive and Environmental Medicine, Graduate School of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan","institution_ids":["https://openalex.org/I96036126"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020491127","display_name":"Atsushi Ueda","orcid":"https://orcid.org/0000-0002-6596-4770","observed_orcids":["https://orcid.org/0000-0002-6596-4770"]},"institutions":[{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Atsushi Ueda","raw_affiliation_strings":["Department of Preventive and Environmental Medicine, Graduate School of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Preventive and Environmental Medicine, Graduate School of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan","institution_ids":["https://openalex.org/I96036126"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5113611550"],"corresponding_institution_ids":["https://openalex.org/I96036126"],"apc_list":{"value":2145,"currency":"USD","value_usd":2145},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"11","issue":"6","first_page":"277","last_page":"285"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12441","display_name":"Porphyrin Metabolism and Disorders","score":0.008100000210106373,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/estradiol","display_name":"estradiol","score":0.9980000257492065},{"id":"https://openalex.org/keywords/lead-poisoning","display_name":"lead poisoning","score":0.9350000023841858},{"id":"https://openalex.org/keywords/heme-biosynthesis","display_name":"heme biosynthesis","score":0.9760000109672546},{"id":"https://openalex.org/keywords/free-erythrocyte-protoporphyrin","display_name":"free erythrocyte protoporphyrin","score":0.9900000095367432},{"id":"https://openalex.org/keywords/delta-aminolevulinic-acid-dehydratase","display_name":"delta-aminolevulinic acid dehydratase","score":0.972000002861023},{"id":"https://openalex.org/keywords/erythrocytes","display_name":"erythrocytes","score":0.6380000114440918},{"id":"https://openalex.org/keywords/bone-marrow","display_name":"bone marrow","score":0.953000009059906},{"id":"https://openalex.org/keywords/liver","display_name":"liver","score":0.8519999980926514},{"id":"https://openalex.org/keywords/hemoglobin","display_name":"hemoglobin","score":0.6629999876022339},{"id":"https://openalex.org/keywords/hematocrit","display_name":"hematocrit","score":0.8939999938011169}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6810126304626465},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6606420278549194},{"id":"https://openalex.org/C2778417259","wikidata":"https://www.wikidata.org/wiki/Q619815","display_name":"Protoporphyrin","level":3,"score":0.5865383148193359},{"id":"https://openalex.org/C2781374117","wikidata":"https://www.wikidata.org/wiki/Q5252382","display_name":"Dehydratase","level":3,"score":0.4972207844257355},{"id":"https://openalex.org/C44538786","wikidata":"https://www.wikidata.org/wiki/Q17816567","display_name":"Porphobilinogen synthase","level":4,"score":0.4686417281627655},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.457151859998703},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.42955929040908813},{"id":"https://openalex.org/C2778917026","wikidata":"https://www.wikidata.org/wiki/Q43041","display_name":"Hemoglobin","level":2,"score":0.42114678025245667},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.41143253445625305},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4107002019882202},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.21471521258354187},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.11978137493133545},{"id":"https://openalex.org/C2779480358","wikidata":"https://www.wikidata.org/wiki/Q422926","display_name":"Porphyrin","level":2,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1007/bf02898017","doi":"https://doi.org/10.1007/bf02898017","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02898017","pdf_url":null,"source":{"id":"https://openalex.org/S110451752","display_name":"Environmental Health and Preventive Medicine","issn_l":"1342-078X","issn":["1342-078X","1347-4715"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental Health and Preventive Medicine","raw_type":"journal-article"},{"id":"doi:10.1265/ehpm.11.277","doi":"https://doi.org/10.1265/ehpm.11.277","is_oa":true,"landing_page_url":"https://doi.org/10.1265/ehpm.11.277","pdf_url":"https://environhealthprevmed.biomedcentral.com/counter/pdf/10.1007/BF02898017","source":{"id":"https://openalex.org/S110451752","display_name":"Environmental Health and Preventive Medicine","issn_l":"1342-078X","issn":["1342-078X","1347-4715"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental Health and Preventive Medicine","raw_type":"journal-article"},{"id":"pmid:21432356","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21432356","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental health and preventive medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2723452","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2723452/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environ Health Prev Med","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.658.1444","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.658.1444","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723452/pdf/12199_2008_Article_BF02898017.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1265/ehpm.11.277","doi":"https://doi.org/10.1265/ehpm.11.277","is_oa":true,"landing_page_url":"https://doi.org/10.1265/ehpm.11.277","pdf_url":"https://environhealthprevmed.biomedcentral.com/counter/pdf/10.1007/BF02898017","source":{"id":"https://openalex.org/S110451752","display_name":"Environmental Health and Preventive Medicine","issn_l":"1342-078X","issn":["1342-078X","1347-4715"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental Health and Preventive Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2045870171.pdf","grobid_xml":"https://content.openalex.org/works/W2045870171.grobid-xml"},"referenced_works_count":50,"referenced_works":["https://openalex.org/W204328526","https://openalex.org/W599696801","https://openalex.org/W1538916116","https://openalex.org/W1895571288","https://openalex.org/W1975849287","https://openalex.org/W1977006130","https://openalex.org/W1980492813","https://openalex.org/W1986732480","https://openalex.org/W1992253727","https://openalex.org/W1995124688","https://openalex.org/W2013188627","https://openalex.org/W2016484540","https://openalex.org/W2018446587","https://openalex.org/W2033004770","https://openalex.org/W2035110819","https://openalex.org/W2043463121","https://openalex.org/W2043873776","https://openalex.org/W2052445646","https://openalex.org/W2060262163","https://openalex.org/W2062468464","https://openalex.org/W2063601624","https://openalex.org/W2090223043","https://openalex.org/W2112311320","https://openalex.org/W2123609512","https://openalex.org/W2124293979","https://openalex.org/W2127489082","https://openalex.org/W2136954850","https://openalex.org/W2164228466","https://openalex.org/W2166596026","https://openalex.org/W2166989095","https://openalex.org/W2171268947","https://openalex.org/W2290596792","https://openalex.org/W2291364880","https://openalex.org/W2313245677","https://openalex.org/W2332072670","https://openalex.org/W2335745492","https://openalex.org/W2406749716","https://openalex.org/W2411437583","https://openalex.org/W2415690350","https://openalex.org/W2418131038","https://openalex.org/W2424052365","https://openalex.org/W2514293958","https://openalex.org/W2988642552","https://openalex.org/W2993252360","https://openalex.org/W3150297831","https://openalex.org/W4205254898","https://openalex.org/W4234263784","https://openalex.org/W4249931337","https://openalex.org/W4302413410","https://openalex.org/W4407198936"],"related_works":["https://openalex.org/W7100273042","https://openalex.org/W1975209248","https://openalex.org/W2439019703","https://openalex.org/W2043873776","https://openalex.org/W2335745492","https://openalex.org/W3184933286","https://openalex.org/W1971714516","https://openalex.org/W2018446587","https://openalex.org/W1995274921","https://openalex.org/W1987535232"],"abstract_inverted_index":null,"counts_by_year":[{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}