{"id":"https://openalex.org/W2045824420","doi":"https://doi.org/10.1016/s0006-8993(96)01132-8","title":"Contribution of sacral spinal cord neurons to the autonomic and somatic consequences of withdrawal from morphine in the rat","display_name":"Contribution of sacral spinal cord neurons to the autonomic and somatic consequences of withdrawal from morphine in the rat","publication_year":1997,"publication_date":"1997-01-01","ids":{"openalex":"https://openalex.org/W2045824420","doi":"https://doi.org/10.1016/s0006-8993(96)01132-8","mag":"2045824420","pmid":"https://pubmed.ncbi.nlm.nih.gov/9037396"},"language":"en","primary_location":{"id":"doi:10.1016/s0006-8993(96)01132-8","doi":"https://doi.org/10.1016/s0006-8993(96)01132-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0006-8993(96)01132-8","pdf_url":null,"source":{"id":"https://openalex.org/S96638545","display_name":"Brain Research","issn_l":"0006-8993","issn":["0006-8993","1872-6240"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016095314","display_name":"Dana S Rohde","orcid":"https://orcid.org/0009-0002-7872-9363","observed_orcids":["https://orcid.org/0009-0002-7872-9363"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Dana S Rohde","raw_affiliation_strings":["Program in Biomedical Sciences, University of California San Francisco 94143-0452, USA","Department of Physiology, University of California San Francisco, San Francisco, CA 94143-0452, USA","Program in Biomedical Sciences, University of California San Francisco, San Francisco, CA 94143-0452, USA","W.M. Keck Foundation Center for Integrative Neuroscience, University of California San Francisco, San Francisco, CA 94143-0452, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Program in Biomedical Sciences, University of California San Francisco 94143-0452, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Physiology, University of California San Francisco, San Francisco, CA 94143-0452, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Program in Biomedical Sciences, University of California San Francisco, San Francisco, CA 94143-0452, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"W.M. Keck Foundation Center for Integrative Neuroscience, University of California San Francisco, San Francisco, CA 94143-0452, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035754174","display_name":"Warren R. McKay","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Warren R McKay","raw_affiliation_strings":["Department of Anesthesia, University of California San Francisco, San Francisco, CA 94143-0648, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesia, University of California San Francisco, San Francisco, CA 94143-0648, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008895579","display_name":"Catherine Abbadie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Catherine Abbadie","raw_affiliation_strings":["Department of Anatomy, University of California San Francisco, San Francisco, CA 94143-0452, USA","W.M. Keck Foundation Center for Integrative Neuroscience, University of California San Francisco, San Francisco, CA 94143-0452, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, University of California San Francisco, San Francisco, CA 94143-0452, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"W.M. Keck Foundation Center for Integrative Neuroscience, University of California San Francisco, San Francisco, CA 94143-0452, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007740596","display_name":"Allan I. Basbaum","orcid":"https://orcid.org/0000-0002-1710-6333","observed_orcids":["https://orcid.org/0000-0002-1710-6333"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Allan I Basbaum","raw_affiliation_strings":["Department of Anatomy, University of California San Francisco, San Francisco, CA 94143-0452, USA","Department of Physiology, University of California San Francisco, San Francisco, CA 94143-0452, USA","Program in Biomedical Sciences, University of California San Francisco, San Francisco, CA 94143-0452, USA","W.M. Keck Foundation Center for Integrative Neuroscience, University of California San Francisco, San Francisco, CA 94143-0452, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, University of California San Francisco, San Francisco, CA 94143-0452, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Physiology, University of California San Francisco, San Francisco, CA 94143-0452, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Program in Biomedical Sciences, University of California San Francisco, San Francisco, CA 94143-0452, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"W.M. Keck Foundation Center for Integrative Neuroscience, University of California San Francisco, San Francisco, CA 94143-0452, USA","institution_ids":["https://openalex.org/I180670191"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5016095314"],"corresponding_institution_ids":["https://openalex.org/I180670191"],"apc_list":{"value":3360,"currency":"USD","value_usd":3360},"apc_paid":null,"fwci":0.8392,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.70069057,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"745","issue":"1-2","first_page":"83","last_page":"95"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.8022000193595886,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.8022000193595886,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.1565999984741211,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10576","display_name":"Opioid Use Disorder Treatment","score":0.012900000438094139,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/morphine-withdrawal","display_name":"morphine withdrawal","score":0.9890000224113464},{"id":"https://openalex.org/keywords/sacral-spinal-cord","display_name":"sacral spinal cord","score":0.921999990940094},{"id":"https://openalex.org/keywords/fos-immunoreactivity","display_name":"Fos-like immunoreactivity","score":0.9430000185966492},{"id":"https://openalex.org/keywords/opioid-antagonists","display_name":"opioid antagonists","score":0.6039999723434448},{"id":"https://openalex.org/keywords/sacral-parasympathetic-nucleus","display_name":"sacral parasympathetic nucleus","score":0.8429999947547913},{"id":"https://openalex.org/keywords/diarrhea","display_name":"diarrhea","score":0.6370000243186951},{"id":"https://openalex.org/keywords/weight-loss","display_name":"weight loss","score":0.8220000267028809},{"id":"https://openalex.org/keywords/capsaicin","display_name":"capsaicin","score":0.9089999794960022},{"id":"https://openalex.org/keywords/intestinal-motility","display_name":"intestinal motility","score":0.7080000042915344},{"id":"https://openalex.org/keywords/neuronal-sensitization","display_name":"neuronal sensitization","score":0.6639999747276306},{"id":"https://openalex.org/keywords/opioid-tolerance","display_name":"opioid tolerance","score":0.5170000195503235}],"concepts":[{"id":"https://openalex.org/C2780775167","wikidata":"https://www.wikidata.org/wiki/Q9606","display_name":"Spinal cord","level":2,"score":0.7053340673446655},{"id":"https://openalex.org/C2776885963","wikidata":"https://www.wikidata.org/wiki/Q245204","display_name":"Antagonist","level":3,"score":0.6157063245773315},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5413588881492615},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5304479002952576},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5245264172554016},{"id":"https://openalex.org/C2781063702","wikidata":"https://www.wikidata.org/wiki/Q427523","display_name":"Opioid","level":3,"score":0.5223754048347473},{"id":"https://openalex.org/C2780051329","wikidata":"https://www.wikidata.org/wiki/Q273169","display_name":"Capsaicin","level":3,"score":0.5163520574569702},{"id":"https://openalex.org/C2777389121","wikidata":"https://www.wikidata.org/wiki/Q81225","display_name":"Morphine","level":2,"score":0.506735622882843},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.4571390748023987},{"id":"https://openalex.org/C2775962371","wikidata":"https://www.wikidata.org/wiki/Q908096","display_name":"Opioid antagonist","level":5,"score":0.455083429813385},{"id":"https://openalex.org/C15490471","wikidata":"https://www.wikidata.org/wiki/Q2734305","display_name":"Nociception","level":3,"score":0.41178637742996216},{"id":"https://openalex.org/C2778750930","wikidata":"https://www.wikidata.org/wiki/Q4540629","display_name":"(+)-Naloxone","level":4,"score":0.15707015991210938},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.14868029952049255},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001341","descriptor_name":"Autonomic Nervous System","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001341","descriptor_name":"Autonomic Nervous System","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D002211","descriptor_name":"Capsaicin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005769","descriptor_name":"Gastrointestinal Motility","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009020","descriptor_name":"Morphine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D009270","descriptor_name":"Naloxone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D009292","descriptor_name":"Narcotic Antagonists","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D009294","descriptor_name":"Narcotics","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D013375","descriptor_name":"Substance Withdrawal Syndrome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013375","descriptor_name":"Substance Withdrawal Syndrome","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D015431","descriptor_name":"Weight Loss","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016760","descriptor_name":"Proto-Oncogene Proteins c-fos","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0006-8993(96)01132-8","doi":"https://doi.org/10.1016/s0006-8993(96)01132-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0006-8993(96)01132-8","pdf_url":null,"source":{"id":"https://openalex.org/S96638545","display_name":"Brain Research","issn_l":"0006-8993","issn":["0006-8993","1872-6240"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Research","raw_type":"journal-article"},{"id":"pmid:9037396","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9037396","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3804584341","display_name":"SPINAL MECHANISMS OF OPIOID ANALGESIA AND TOLERANCE","funder_award_id":"R01DA008377","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"}],"funders":[{"id":"https://openalex.org/F4320337347","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":71,"referenced_works":["https://openalex.org/W29671035","https://openalex.org/W70761295","https://openalex.org/W1506673182","https://openalex.org/W1883060277","https://openalex.org/W1968858188","https://openalex.org/W1972250954","https://openalex.org/W1973806783","https://openalex.org/W1974224112","https://openalex.org/W1975464141","https://openalex.org/W1979149694","https://openalex.org/W1991774850","https://openalex.org/W1996364906","https://openalex.org/W1997894100","https://openalex.org/W1998191034","https://openalex.org/W1998655323","https://openalex.org/W2004193077","https://openalex.org/W2005656584","https://openalex.org/W2006330090","https://openalex.org/W2006917026","https://openalex.org/W2008264529","https://openalex.org/W2011692127","https://openalex.org/W2012659957","https://openalex.org/W2017288998","https://openalex.org/W2027190963","https://openalex.org/W2028955729","https://openalex.org/W2032220787","https://openalex.org/W2032997748","https://openalex.org/W2033323256","https://openalex.org/W2034053403","https://openalex.org/W2035502902","https://openalex.org/W2036148622","https://openalex.org/W2039984508","https://openalex.org/W2043323520","https://openalex.org/W2045745519","https://openalex.org/W2048929539","https://openalex.org/W2050445424","https://openalex.org/W2051001717","https://openalex.org/W2052354365","https://openalex.org/W2058693989","https://openalex.org/W2060058702","https://openalex.org/W2060645146","https://openalex.org/W2062177483","https://openalex.org/W2074630300","https://openalex.org/W2077755865","https://openalex.org/W2079154359","https://openalex.org/W2084043489","https://openalex.org/W2085573535","https://openalex.org/W2089549038","https://openalex.org/W2091652749","https://openalex.org/W2102620584","https://openalex.org/W2107224500","https://openalex.org/W2135468119","https://openalex.org/W2149454735","https://openalex.org/W2167243738","https://openalex.org/W2186426742","https://openalex.org/W2194491439","https://openalex.org/W2211838531","https://openalex.org/W2214956132","https://openalex.org/W2253456957","https://openalex.org/W2288981481","https://openalex.org/W2294497822","https://openalex.org/W2294813519","https://openalex.org/W2308736610","https://openalex.org/W2308789241","https://openalex.org/W2333750703","https://openalex.org/W2396512995","https://openalex.org/W2396762482","https://openalex.org/W2417908827","https://openalex.org/W2431721497","https://openalex.org/W2478765828","https://openalex.org/W2800843908"],"related_works":["https://openalex.org/W1996067634","https://openalex.org/W1974224112","https://openalex.org/W1794995310","https://openalex.org/W2005656584","https://openalex.org/W2073033020","https://openalex.org/W2019277269","https://openalex.org/W2011727049","https://openalex.org/W2410999611","https://openalex.org/W2366458226","https://openalex.org/W371440820"],"abstract_inverted_index":null,"counts_by_year":[{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}