{"id":"https://openalex.org/W2045676515","doi":"https://doi.org/10.1016/j.jaci.2007.02.034","title":"Tradition and innovation: Finding the right balance","display_name":"Tradition and innovation: Finding the right balance","publication_year":2007,"publication_date":"2007-04-01","ids":{"openalex":"https://openalex.org/W2045676515","doi":"https://doi.org/10.1016/j.jaci.2007.02.034","mag":"2045676515","pmid":"https://pubmed.ncbi.nlm.nih.gov/17418659"},"language":"en","primary_location":{"id":"doi:10.1016/j.jaci.2007.02.034","doi":"https://doi.org/10.1016/j.jaci.2007.02.034","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jaci.2007.02.034","pdf_url":null,"source":{"id":"https://openalex.org/S108525051","display_name":"Journal of Allergy and Clinical Immunology","issn_l":"0091-6749","issn":["0091-6749","1085-8725","1097-6825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043192106","display_name":"Stephen R. Durham","orcid":"https://orcid.org/0000-0001-5264-6207","observed_orcids":["https://orcid.org/0000-0001-5264-6207"]},"institutions":[{"id":"https://openalex.org/I4210096640","display_name":"Royal Brompton Hospital","ror":"https://ror.org/00cv4n034","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800036501","https://openalex.org/I4210096640"]},{"id":"https://openalex.org/I4210141571","display_name":"Asthma UK","ror":"https://ror.org/03z7xev21","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2801572420","https://openalex.org/I4210141571"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Stephen R. Durham","raw_affiliation_strings":["From MRC and Asthma UK Centre for Allergic Mechanisms of Asthma, Section of Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College and Royal Brompton Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From MRC and Asthma UK Centre for Allergic Mechanisms of Asthma, Section of Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College and Royal Brompton Hospital","institution_ids":["https://openalex.org/I4210096640","https://openalex.org/I4210141571","https://openalex.org/I47508984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5043192106"],"corresponding_institution_ids":["https://openalex.org/I4210096640","https://openalex.org/I4210141571","https://openalex.org/I47508984"],"apc_list":{"value":4900,"currency":"USD","value_usd":4900},"apc_paid":null,"fwci":0.1686,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.18099548,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"119","issue":"4","first_page":"792","last_page":"795"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/allergen-immunotherapy","display_name":"allergen immunotherapy","score":0.9990000128746033},{"id":"https://openalex.org/keywords/subcutaneous-immunotherapy","display_name":"subcutaneous immunotherapy","score":0.9369999766349792},{"id":"https://openalex.org/keywords/allergen-extracts","display_name":"allergen extracts","score":0.9150000214576721},{"id":"https://openalex.org/keywords/ige-mediated-allergy","display_name":"IgE-mediated allergy","score":0.8769999742507935},{"id":"https://openalex.org/keywords/maintenance-therapy","display_name":"maintenance therapy","score":0.5049999952316284},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.6740000247955322}],"concepts":[{"id":"https://openalex.org/C168031717","wikidata":"https://www.wikidata.org/wiki/Q1530280","display_name":"Balance (ability)","level":2,"score":0.6678361892700195},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.35591983795166016},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.32400768995285034},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.2806217670440674},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.062257081270217896}],"mesh":[{"descriptor_ui":"D000075202","descriptor_name":"Contraindications","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000286","descriptor_name":"Administration, Sublingual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000485","descriptor_name":"Allergens","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D000485","descriptor_name":"Allergens","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000485","descriptor_name":"Allergens","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D003888","descriptor_name":"Desensitization, Immunologic","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D003888","descriptor_name":"Desensitization, Immunologic","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D007279","descriptor_name":"Injections, Subcutaneous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.jaci.2007.02.034","doi":"https://doi.org/10.1016/j.jaci.2007.02.034","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jaci.2007.02.034","pdf_url":null,"source":{"id":"https://openalex.org/S108525051","display_name":"Journal of Allergy and Clinical Immunology","issn_l":"0091-6749","issn":["0091-6749","1085-8725","1097-6825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology","raw_type":"journal-article"},{"id":"pmid:17418659","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17418659","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of allergy and clinical immunology","raw_type":"Editorial"},{"id":"pmh:oai:bibmed.ucla.edu.ve:T070000065085/5","doi":null,"is_oa":false,"landing_page_url":"http://bibmed.ucla.edu.ve/cgi-win/be_alex.exe?Acceso=T070000065085/5&Nombrebd=bmucla","pdf_url":null,"source":{"id":"https://openalex.org/S7407064131","display_name":"UCLA - Biblioteca de Ciencias de la Salud","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I19325673","host_organization_name":"Universidad Centroccidental Lisandro Alvarado","host_organization_lineage":["https://openalex.org/I19325673"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W109138240","https://openalex.org/W1495964112","https://openalex.org/W1942126698","https://openalex.org/W1958210619","https://openalex.org/W1964354442","https://openalex.org/W1973688027","https://openalex.org/W1976640573","https://openalex.org/W1981352260","https://openalex.org/W1984973837","https://openalex.org/W1993775186","https://openalex.org/W1996404326","https://openalex.org/W1997120806","https://openalex.org/W2007523022","https://openalex.org/W2013055277","https://openalex.org/W2026657673","https://openalex.org/W2031202979","https://openalex.org/W2033232206","https://openalex.org/W2035319060","https://openalex.org/W2037476918","https://openalex.org/W2041068026","https://openalex.org/W2041303617","https://openalex.org/W2052063445","https://openalex.org/W2054698585","https://openalex.org/W2060411425","https://openalex.org/W2068471769","https://openalex.org/W2069362757","https://openalex.org/W2074525021","https://openalex.org/W2085196853","https://openalex.org/W2098913651","https://openalex.org/W2110068169","https://openalex.org/W2112571043","https://openalex.org/W2124060773","https://openalex.org/W2125803815","https://openalex.org/W2132441138","https://openalex.org/W2142388937","https://openalex.org/W2151978148","https://openalex.org/W2153011983","https://openalex.org/W2156787187","https://openalex.org/W2158341249","https://openalex.org/W2159285246","https://openalex.org/W2166685437","https://openalex.org/W2312829609","https://openalex.org/W2330540142","https://openalex.org/W2341810285","https://openalex.org/W2465186865","https://openalex.org/W2482294204","https://openalex.org/W4214838273"],"related_works":["https://openalex.org/W2320775992","https://openalex.org/W2936510925","https://openalex.org/W7216663951","https://openalex.org/W4306411699","https://openalex.org/W2156376278","https://openalex.org/W2398919071","https://openalex.org/W2062913649","https://openalex.org/W2598703698","https://openalex.org/W2116896714","https://openalex.org/W4239980427"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}