{"id":"https://openalex.org/W2045593028","doi":"https://doi.org/10.1158/1538-7445.am10-3435","title":"Abstract 3435: VEGF or VEGF and EGF receptor signaling inhibition by cediranib or vandetanib enhances the therapeutic effects of chemoradiation in an orthotopic small cell lung cancer model","display_name":"Abstract 3435: VEGF or VEGF and EGF receptor signaling inhibition by cediranib or vandetanib enhances the therapeutic effects of chemoradiation in an orthotopic small cell lung cancer model","publication_year":2010,"publication_date":"2010-04-01","ids":{"openalex":"https://openalex.org/W2045593028","doi":"https://doi.org/10.1158/1538-7445.am10-3435","mag":"2045593028"},"language":"en","primary_location":{"id":"doi:10.1158/1538-7445.am10-3435","doi":"https://doi.org/10.1158/1538-7445.am10-3435","is_oa":false,"landing_page_url":"https://doi.org/10.1158/1538-7445.am10-3435","pdf_url":null,"source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Keiko Hosho","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Keiko Hosho","raw_affiliation_strings":["1MD Anderson Cancer Center, Houston, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060222943","display_name":"Ritsuko U Komaki","orcid":"https://orcid.org/0000-0003-0084-6017","observed_orcids":["https://orcid.org/0000-0003-0084-6017"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ritsuko Komaki","raw_affiliation_strings":["1MD Anderson Cancer Center, Houston, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109162407","display_name":"Ramesh C. Tailor","orcid":"https://orcid.org/0000-0002-8144-2622","observed_orcids":["https://orcid.org/0000-0002-8144-2622"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ramesh C. Tailor","raw_affiliation_strings":["1MD Anderson Cancer Center, Houston, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107537939","display_name":"Anderson Joseph Ryan","orcid":"https://orcid.org/0000-0001-6241-7969","observed_orcids":["https://orcid.org/0000-0001-6241-7969"]},"institutions":[{"id":"https://openalex.org/I105036370","display_name":"AstraZeneca (United Kingdom)","ror":"https://ror.org/04r9x1a08","country_code":"GB","type":"company","lineage":["https://openalex.org/I105036370"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anderson Ryan","raw_affiliation_strings":["2AstraZeneca, Alderley Park, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2AstraZeneca, Alderley Park, United Kingdom","institution_ids":["https://openalex.org/I105036370"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087689900","display_name":"Juliane Margarete J\u00fcrgensmeier","orcid":"https://orcid.org/0000-0001-8438-2429","observed_orcids":["https://orcid.org/0000-0001-8438-2429"]},"institutions":[{"id":"https://openalex.org/I105036370","display_name":"AstraZeneca (United Kingdom)","ror":"https://ror.org/04r9x1a08","country_code":"GB","type":"company","lineage":["https://openalex.org/I105036370"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Juliane M. Ju\u0308rgensmeier","raw_affiliation_strings":["2AstraZeneca, Alderley Park, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2AstraZeneca, Alderley Park, United Kingdom","institution_ids":["https://openalex.org/I105036370"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039299082","display_name":"Paul D. Smith","orcid":"https://orcid.org/0000-0002-2812-5978","observed_orcids":["https://orcid.org/0000-0002-2812-5978"]},"institutions":[{"id":"https://openalex.org/I105036370","display_name":"AstraZeneca (United Kingdom)","ror":"https://ror.org/04r9x1a08","country_code":"GB","type":"company","lineage":["https://openalex.org/I105036370"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Paul D. Smith","raw_affiliation_strings":["2AstraZeneca, Alderley Park, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2AstraZeneca, Alderley Park, United Kingdom","institution_ids":["https://openalex.org/I105036370"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000902150","display_name":"Joerg J. Jacoby","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joerg J. Jacoby","raw_affiliation_strings":["1MD Anderson Cancer Center, Houston, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090450331","display_name":"Osamu Takahashi","orcid":"https://orcid.org/0000-0002-6454-3990","observed_orcids":["https://orcid.org/0000-0002-6454-3990"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Osamu Takahashi","raw_affiliation_strings":["1MD Anderson Cancer Center, Houston, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112530593","display_name":"Maria V. Korshunova","orcid":"https://orcid.org/0000-0003-4391-8228","observed_orcids":["https://orcid.org/0000-0003-4391-8228"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maria V. Korshunova","raw_affiliation_strings":["1MD Anderson Cancer Center, Houston, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044193450","display_name":"Baruch Erez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Baruch Erez","raw_affiliation_strings":["1MD Anderson Cancer Center, Houston, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008593691","display_name":"Roy S. Herbst","orcid":"https://orcid.org/0000-0003-2535-5847","observed_orcids":["https://orcid.org/0000-0003-2535-5847"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Roy S. Herbst","raw_affiliation_strings":["1MD Anderson Cancer Center, Houston, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111770515","display_name":"Michael S. O\u2019Reilly","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael S. O'Reilly","raw_affiliation_strings":["1MD Anderson Cancer Center, Houston, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1MD Anderson Cancer Center, Houston, TX","institution_ids":["https://openalex.org/I1343551460"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"70","issue":"8_Supplement","first_page":"3435","last_page":"3435"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.5127000212669373,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.5127000212669373,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12334","display_name":"Lung Cancer Research Studies","score":0.46700000762939453,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/small-cell-lung-cancer","display_name":"small cell lung cancer","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cediranib","display_name":"cediranib","score":0.9259999990463257},{"id":"https://openalex.org/keywords/vandetanib","display_name":"vandetanib","score":0.996999979019165},{"id":"https://openalex.org/keywords/vegf-receptor-inhibition","display_name":"VEGF receptor inhibition","score":0.9259999990463257},{"id":"https://openalex.org/keywords/egfr-inhibition","display_name":"EGFR inhibition","score":0.9710000157356262},{"id":"https://openalex.org/keywords/chemoradiotherapy","display_name":"chemoradiotherapy","score":0.9150000214576721},{"id":"https://openalex.org/keywords/radiosensitization","display_name":"radiosensitization","score":0.9879999756813049},{"id":"https://openalex.org/keywords/anti-angiogenic-therapy","display_name":"anti-angiogenic therapy","score":0.890999972820282},{"id":"https://openalex.org/keywords/orthotopic-tumor-model","display_name":"orthotopic tumor model","score":0.7870000004768372},{"id":"https://openalex.org/keywords/cisplatin","display_name":"cisplatin","score":0.777999997138977},{"id":"https://openalex.org/keywords/irinotecan","display_name":"irinotecan","score":0.9769999980926514},{"id":"https://openalex.org/keywords/lymph-node-metastasis","display_name":"lymph node metastasis","score":0.8330000042915344},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.6660000085830688},{"id":"https://openalex.org/keywords/nci-h187-cells","display_name":"NCI-H187 cells","score":0.8240000009536743},{"id":"https://openalex.org/keywords/tumor-growth-inhibition","display_name":"tumor growth inhibition","score":0.6129999756813049},{"id":"https://openalex.org/keywords/mediastinal-lymph-nodes","display_name":"mediastinal lymph nodes","score":0.5680000185966492}],"concepts":[{"id":"https://openalex.org/C2780333294","wikidata":"https://www.wikidata.org/wiki/Q7914515","display_name":"Vandetanib","level":4,"score":0.9472727179527283},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8111454248428345},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.6170027256011963},{"id":"https://openalex.org/C2779438470","wikidata":"https://www.wikidata.org/wiki/Q424401","display_name":"Epidermal growth factor receptor","level":3,"score":0.46186357736587524},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.4244897961616516},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4046691954135895},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.39328718185424805},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.36007142066955566},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3481212258338928},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.20876088738441467},{"id":"https://openalex.org/C42362537","wikidata":"https://www.wikidata.org/wiki/Q87099740","display_name":"Tyrosine kinase","level":3,"score":0.08021992444992065}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1538-7445.am10-3435","doi":"https://doi.org/10.1158/1538-7445.am10-3435","is_oa":false,"landing_page_url":"https://doi.org/10.1158/1538-7445.am10-3435","pdf_url":null,"source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2270589427","https://openalex.org/W884027945","https://openalex.org/W2057391235","https://openalex.org/W4402115543","https://openalex.org/W1574639809","https://openalex.org/W2024760455","https://openalex.org/W2256729348","https://openalex.org/W1996608941","https://openalex.org/W3167236746","https://openalex.org/W2057101444"],"abstract_inverted_index":{"Abstract":[0],"Background:":[1],"Small":[2],"cell":[3],"lung":[4,98,135,173,196,204,235,275,300,369,389],"cancer":[5],"(SCLC)":[6],"is":[7],"associated":[8],"with":[9,109,152,189,199,214,224,230,243,246,257,272,325,383,404],"a":[10,200,231,248,303],"poor":[11],"prognosis":[12],"and":[13,29,45,55,100,125,136,170,176,180,259,285,327,345,352,354,371,392,414],"can":[14],"recur":[15],"even":[16],"after":[17,92],"chemoradiation":[18,258,405],"therapy.":[19,360,397],"In":[20,330],"the":[21,26,78,101,133,265,281,356,378,384,410,418,435,440],"current":[22],"study,":[23],"we":[24],"evaluated":[25],"therapeutic,":[27],"antiangiogenic,":[28],"radiosensitizing":[30,362],"effects":[31,219,315,357,363],"of":[32,40,53,61,67,81,163,220,269,280,299,358,364,380,388,400,412,434,439],"cediranib":[33,112,149,227,260,320,342,365,401],"(RECENTINTM;":[34],"AZD2171),":[35],"an":[36,49,58,331],"orally":[37,50],"available":[38,51],"inhibitor":[39,52],"all":[41,166,310,338],"3":[42,339],"VEGF":[43],"receptors,":[44],"vandetanib":[46,116,147,225,262,322,348,367,403],"(ZACTIMATM;":[47],"ZD6474),":[48],"VEGFR":[54,344],"EGFR,":[56],"in":[57,140,150,202,233,264,278,288,306,309,368,423],"orthotopic":[59,332],"model":[60],"human":[62,72],"SCLC":[63,68,73,270,333,413,424],"that":[64],"mimics":[65],"patterns":[66],"progression.":[69],"Methods:":[70],"NCI-H187":[71],"cells":[74],"were":[75,90,104,168,183,228,294,316],"injected":[76],"into":[77],"left":[79,134,203,234],"lungs":[80],"nude":[82],"mice.":[83],"To":[84],"confirm":[85],"tumor":[86,174,197,350,390],"growth,":[87],"5":[88,141],"mice":[89,103,167,284],"sacrificed":[91,169],"14":[93],"days.":[94],"All":[95,292],"had":[96],"visible":[97],"tumors":[99,179,276,301,370],"remaining":[102],"randomized":[105],"(8/group)":[106],"to":[107,132],"treatment":[108,311,411],"vehicle":[110],"(control),":[111],"(3":[113],"mg/kg/day":[114,118],"po),":[115,119],"(25":[117],"doublet":[120,381],"chemotherapy":[121,326],"(CDDP":[122],"8":[123,282],"mg/kg":[124],"CPT-11":[126],"15":[127],"mg/kg,":[128],"weekly":[129],"ip),":[130],"radiation":[131,153,194,221,359],"mediastinum":[137],"(20":[138],"Gy":[139],"fractions":[142],"over":[143],"2":[144],"weeks),":[145],"or":[146,148,193,210,226,239,261,321,343,366,402],"combination":[151],"and/or":[154],"chemotherapy.":[155],"After":[156],"45":[157],"days,":[158],"when":[159,319],"controls":[160],"showed":[161],"signs":[162],"becoming":[164],"moribund,":[165],"assessed":[171],"for":[172,409,420,443],"growth":[175,198,351,391],"metastasis.":[177,254],"Lung":[178],"adjacent":[181],"tissues":[182],"analyzed":[184],"by":[185,206,237,341,347,377,395],"immunohistochemistry.":[186],"Results:":[187],"Treatment":[188],"vandetanib,":[190],"cediranib,":[191],"chemotherapy,":[192,382],"inhibited":[195,349],"reduction":[201,232,305],"weight":[205,236],"56,":[207],"60,":[208],"87,":[209],"86%,":[211],"respectively,":[212,241],"compared":[213,242],"control":[215,244],"(P<0.03).":[216],"The":[217,313,361,398],"antitumor":[218],"therapy":[222,256,336,406],"combined":[223,324],"similar":[229],"80":[238],"83%,":[240],"(P<0.0001)":[245],"only":[247,289],"marginal":[249],"impact":[250],"upon":[251],"mediastinal":[252,393],"lymphatic":[253,286],"Trimodality":[255],"resulted":[263],"near":[266,385],"complete":[267,386],"suppression":[268,387],"progression":[271,353],"no":[273],"gross":[274],"observed":[277],"any":[279],"treated":[283],"metastasis":[287,394],"1":[290],"mouse.":[291],"treatments":[293],"well":[295],"tolerated.":[296],"Immunohistochemical":[297],"analyses":[298],"revealed":[302],"significant":[304],"microvessel":[307],"density":[308],"groups.":[312],"antiangiogenic":[314],"substantially":[317],"enhanced":[318,355],"was":[323,374],"radiation.":[328],"Conclusion:":[329],"model,":[334],"targeted":[335],"against":[337],"VEGFRs":[340],"EGFR":[346],"their":[372],"vasculature":[373],"further":[375],"improved":[376],"addition":[379],"trimodality":[396],"use":[399],"holds":[407],"promise":[408],"our":[415],"data":[416],"provide":[417],"basis":[419],"clinical":[421],"trials":[422],"patients.":[425],"Citation":[426],"Format:":[427],"{Authors}.":[428],"{Abstract":[429],"title}":[430],"[abstract].":[431],"In:":[432],"Proceedings":[433],"101st":[436],"Annual":[437],"Meeting":[438],"American":[441],"Association":[442],"Cancer":[444,454],"Research;":[445],"2010":[446],"Apr":[447],"17-21;":[448],"Washington,":[449],"DC.":[450],"Philadelphia":[451],"(PA):":[452],"AACR;":[453],"Res":[455],"2010;70(8":[456],"Suppl):Abstract":[457],"nr":[458],"3435.":[459]},"counts_by_year":[],"updated_date":"2026-10-17T09:40:24.721904","created_date":"2016-06-24T00:00:00"}