{"id":"https://openalex.org/W2045527675","doi":"https://doi.org/10.1096/fj.06-070573","title":"Epidermal growth factor receptor pathway substrate 8 (Eps8) is a novel regulator of cell adhesion and the blood\u2010testis barrier integrity in the seminiferous epithelium","display_name":"Epidermal growth factor receptor pathway substrate 8 (Eps8) is a novel regulator of cell adhesion and the blood\u2010testis barrier integrity in the seminiferous epithelium","publication_year":2009,"publication_date":"2009-03-17","ids":{"openalex":"https://openalex.org/W2045527675","doi":"https://doi.org/10.1096/fj.06-070573","mag":"2045527675","pmid":"https://pubmed.ncbi.nlm.nih.gov/19293393","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2717761"},"language":"en","primary_location":{"id":"doi:10.1096/fj.06-070573","doi":"https://doi.org/10.1096/fj.06-070573","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fj.06-070573","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2717761","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000133136","display_name":"Pearl P.Y. Lie","orcid":"https://orcid.org/0000-0001-5838-958X","observed_orcids":["https://orcid.org/0000-0001-5838-958X"]},"institutions":[{"id":"https://openalex.org/I4210132262","display_name":"Population Council","ror":"https://ror.org/03zjj0p70","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210132262"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pearl P. Y. Lie","raw_affiliation_strings":["Center for Biomedical Research Population Council New York New York USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biomedical Research Population Council New York New York USA","institution_ids":["https://openalex.org/I4210132262"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041273456","display_name":"Dolores D. Mruk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210132262","display_name":"Population Council","ror":"https://ror.org/03zjj0p70","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210132262"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dolores D. Mruk","raw_affiliation_strings":["Center for Biomedical Research Population Council New York New York USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biomedical Research Population Council New York New York USA","institution_ids":["https://openalex.org/I4210132262"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048483050","display_name":"Will M. Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Will M. Lee","raw_affiliation_strings":["School of Biological Sciences The University of Hong Kong Hong Kong China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological Sciences The University of Hong Kong Hong Kong China","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072413923","display_name":"C. Yan Cheng","orcid":"https://orcid.org/0000-0003-3117-3791","observed_orcids":["https://orcid.org/0000-0003-3117-3791"]},"institutions":[{"id":"https://openalex.org/I4210132262","display_name":"Population Council","ror":"https://ror.org/03zjj0p70","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210132262"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"C. Yan Cheng","raw_affiliation_strings":["Center for Biomedical Research Population Council New York New York USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biomedical Research Population Council New York New York USA","institution_ids":["https://openalex.org/I4210132262"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5072413923"],"corresponding_institution_ids":["https://openalex.org/I4210132262"],"apc_list":{"value":3740,"currency":"USD","value_usd":3740},"apc_paid":null,"fwci":11.7805,"has_fulltext":false,"cited_by_count":154,"citation_normalized_percentile":{"value":0.98613985,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"23","issue":"8","first_page":"2555","last_page":"2567"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/eps8","display_name":"Eps8","score":0.9909999966621399},{"id":"https://openalex.org/keywords/blood-testis-barrier","display_name":"blood-testis barrier","score":0.8579999804496765},{"id":"https://openalex.org/keywords/seminiferous-epithelium","display_name":"seminiferous epithelium","score":0.9810000061988831},{"id":"https://openalex.org/keywords/cell-adhesion","display_name":"cell adhesion","score":0.9470000267028809},{"id":"https://openalex.org/keywords/ectoplasmic-specialization","display_name":"ectoplasmic specialization","score":0.9549999833106995},{"id":"https://openalex.org/keywords/sertoli-cells","display_name":"Sertoli cells","score":0.8970000147819519},{"id":"https://openalex.org/keywords/tight-junctions","display_name":"tight junctions","score":0.8700000047683716},{"id":"https://openalex.org/keywords/occludin","display_name":"occludin","score":0.9819999933242798},{"id":"https://openalex.org/keywords/zo-1","display_name":"ZO-1","score":0.996999979019165},{"id":"https://openalex.org/keywords/actin-cytoskeleton","display_name":"actin cytoskeleton","score":0.9020000100135803},{"id":"https://openalex.org/keywords/adjudin","display_name":"adjudin","score":0.7080000042915344},{"id":"https://openalex.org/keywords/rnai-knockdown","display_name":"RNAi knockdown","score":0.6050000190734863}],"concepts":[{"id":"https://openalex.org/C2775962179","wikidata":"https://www.wikidata.org/wiki/Q2013337","display_name":"Occludin","level":3,"score":0.8330105543136597},{"id":"https://openalex.org/C2636012","wikidata":"https://www.wikidata.org/wiki/Q489842","display_name":"Blood\u2013testis barrier","level":4,"score":0.740142822265625},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.7260991334915161},{"id":"https://openalex.org/C177779419","wikidata":"https://www.wikidata.org/wiki/Q1053832","display_name":"Tight junction","level":2,"score":0.6430016160011292},{"id":"https://openalex.org/C2779122487","wikidata":"https://www.wikidata.org/wiki/Q281579","display_name":"Germ cell","level":3,"score":0.56187903881073},{"id":"https://openalex.org/C529295009","wikidata":"https://www.wikidata.org/wiki/Q41301","display_name":"Epithelium","level":2,"score":0.5368611812591553},{"id":"https://openalex.org/C2781068068","wikidata":"https://www.wikidata.org/wiki/Q195614","display_name":"Sertoli cell","level":3,"score":0.5226042866706848},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.45257893204689026},{"id":"https://openalex.org/C151166631","wikidata":"https://www.wikidata.org/wiki/Q904514","display_name":"Focal adhesion","level":3,"score":0.4485251009464264},{"id":"https://openalex.org/C85789140","wikidata":"https://www.wikidata.org/wiki/Q187640","display_name":"Cell adhesion","level":3,"score":0.42304807901382446},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3719565272331238},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.2724555730819702},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.24940261244773865},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2229224443435669},{"id":"https://openalex.org/C123765429","wikidata":"https://www.wikidata.org/wiki/Q36961","display_name":"Spermatogenesis","level":2,"score":0.2171531617641449},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.06429564952850342},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000199","descriptor_name":"Actins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001814","descriptor_name":"Blood-Testis Barrier","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001814","descriptor_name":"Blood-Testis Barrier","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006834","descriptor_name":"Hydrazines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007191","descriptor_name":"Indazoles","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D012670","descriptor_name":"Seminiferous Epithelium","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D012670","descriptor_name":"Seminiferous Epithelium","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012670","descriptor_name":"Seminiferous Epithelium","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D012708","descriptor_name":"Sertoli Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D012708","descriptor_name":"Sertoli Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012708","descriptor_name":"Sertoli Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013087","descriptor_name":"Spermatids","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D013087","descriptor_name":"Spermatids","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013087","descriptor_name":"Spermatids","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013091","descriptor_name":"Spermatogenesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017931","descriptor_name":"DNA Primers","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D022005","descriptor_name":"Adherens Junctions","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D022005","descriptor_name":"Adherens Junctions","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D034622","descriptor_name":"RNA Interference","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D048868","descriptor_name":"Adaptor Proteins, Signal Transducing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1096/fj.06-070573","doi":"https://doi.org/10.1096/fj.06-070573","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fj.06-070573","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2001921","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2717761","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2717761","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2717761","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FASEB J","raw_type":"Text"},{"id":"pmid:19293393","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19293393","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FASEB journal : official publication of the Federation of American Societies for Experimental Biology","raw_type":"Journal Article"},{"id":"pmh:oai:hub.hku.hk:10722/60659","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10722/60659","pdf_url":null,"source":{"id":"https://openalex.org/S4377196271","display_name":"The HKU Scholars Hub (University of Hong Kong)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I889458895","host_organization_name":"University of Hong Kong","host_organization_lineage":["https://openalex.org/I889458895"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2001921","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2717761","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6240000128746033}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1409385275","display_name":null,"funder_award_id":"R03-HD051512","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G2880103442","display_name":"Biology of the Blood-Testis Barrier","funder_award_id":"R01HD056034","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G3978732592","display_name":"An in vivo model to study blood-testis barrier dynamics","funder_award_id":"5r03hd051512-02","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":59,"referenced_works":["https://openalex.org/W591684825","https://openalex.org/W1510776906","https://openalex.org/W1514347000","https://openalex.org/W1532919526","https://openalex.org/W1533987526","https://openalex.org/W1555234576","https://openalex.org/W1600430222","https://openalex.org/W1822999471","https://openalex.org/W1965986672","https://openalex.org/W1966217830","https://openalex.org/W1968907717","https://openalex.org/W1972197584","https://openalex.org/W1983735042","https://openalex.org/W1987082843","https://openalex.org/W1990739542","https://openalex.org/W1990883677","https://openalex.org/W1991945474","https://openalex.org/W1994133047","https://openalex.org/W2011745438","https://openalex.org/W2014913899","https://openalex.org/W2024795352","https://openalex.org/W2029804435","https://openalex.org/W2042342900","https://openalex.org/W2043615134","https://openalex.org/W2046587126","https://openalex.org/W2047512850","https://openalex.org/W2052213010","https://openalex.org/W2054173047","https://openalex.org/W2059787231","https://openalex.org/W2062778620","https://openalex.org/W2064488645","https://openalex.org/W2064855160","https://openalex.org/W2065959414","https://openalex.org/W2071862896","https://openalex.org/W2075229853","https://openalex.org/W2077080652","https://openalex.org/W2077858517","https://openalex.org/W2078122977","https://openalex.org/W2079122334","https://openalex.org/W2079597974","https://openalex.org/W2081958807","https://openalex.org/W2092485642","https://openalex.org/W2093187124","https://openalex.org/W2097300990","https://openalex.org/W2097886701","https://openalex.org/W2103159925","https://openalex.org/W2108433727","https://openalex.org/W2108935114","https://openalex.org/W2119888224","https://openalex.org/W2120597716","https://openalex.org/W2127370867","https://openalex.org/W2128016220","https://openalex.org/W2129649116","https://openalex.org/W2131543145","https://openalex.org/W2138388305","https://openalex.org/W2164929923","https://openalex.org/W2252403865","https://openalex.org/W2346755418","https://openalex.org/W4388299920"],"related_works":["https://openalex.org/W2139673058","https://openalex.org/W2021969505","https://openalex.org/W1993413596","https://openalex.org/W2064370516","https://openalex.org/W2089867981","https://openalex.org/W2015912703","https://openalex.org/W2023403043","https://openalex.org/W2003695272","https://openalex.org/W1557197255","https://openalex.org/W2107219745"],"abstract_inverted_index":{"In":[0,96,140],"the":[1,12,17,38,48,89,105,110,121,124,132,146,174,206,211],"seminiferous":[2,175,212],"epithelium,":[3],"Eps8":[4,34,51,86,113,135,144,162],"is":[5,27,163,198],"localized":[6],"to":[7,79,117],"actin\u2010based":[8],"cell":[9,53,59,94,98,150,168,203],"junctions":[10],"at":[11,88],"blood\u2010testis":[13,207],"barrier":[14,103,208],"(BTB)":[15],"and":[16,43,120,129,152,170,205],"apical":[18,44,90],"ectoplasmic":[19],"specialization":[20],"(ES)":[21],"in":[22,30,52,57,63,67,107,136,145,173,210],"stage":[23,31],"V\u2014VI":[24],"tubules":[25],"but":[26],"considerably":[28],"diminished":[29],"VIII":[32],"tubules.":[33],"down\u2010regulation":[35],"coincides":[36],"with":[37,74,100,156],"time":[39],"of":[40,50,112,123,134,143,167,202],"BTB":[41,106,138,153,171],"restructuring":[42],"ES":[45,91],"disassembly,":[46],"implicating":[47],"role":[49],"adhesion.":[54],"Its":[55],"involvement":[56],"Sertoli\u2010germ":[58],"adhesion":[60,169,204],"was":[61],"substantiated":[62],"studies":[64],"using":[65],"an":[66],"vivo":[68,108,141],"animal":[69],"model":[70],"by":[71,114],"treating":[72],"rats":[73],"1\u2010(2,4\u2010dichlorobenzy)\u20101H\u2010indazole\u2010":[75],"3\u2010":[76],"carbohydrazide":[77],"(adjudin)":[78],"induce":[80],"anchoring":[81],"junction":[82,126],"restructuring,":[83],"during":[84],"which":[85],"disappeared":[87],"before":[92],"germ":[93,149],"departure.":[95],"Sertoli":[97],"cultures":[99],"established":[101],"permeability":[102],"mimicking":[104],",":[109],"knockdown":[111,142],"RNAi":[115],"led":[116],"F\u2010actin":[118],"disorganization":[119],"mislocalization":[122],"tight":[125],"proteins":[127],"occludin":[128,157],"ZO\u20101,":[130],"suggesting":[131],"function":[133],"maintaining":[137],"integrity.":[139],"testis":[147],"caused":[148],"sloughing":[151],"damage,":[154],"concomitant":[155],"mislocalization,":[158],"further":[159],"validating":[160],"that":[161],"a":[164,199],"novel":[165,200],"regulator":[166,201],"integrity":[172,209],"epithelium.\u2014":[176],"Lie,":[177],"P.":[178,179],"Y.,":[180],"Mruk,":[181],"D.":[182],"D.,":[183],"Lee,":[184],"W.":[185],"M.,":[186],"Cheng,":[187],"C.":[188],"Y.":[189],"Epidermal":[190],"growth":[191],"factor":[192],"receptor":[193],"pathway":[194],"substrate":[195],"8":[196],"(Eps8)":[197],"epithelium.":[213],"FASEB":[214],"J.":[215],"23,":[216],"2555\u20132567":[217],"(2009)":[218]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":13},{"year":2014,"cited_by_count":14},{"year":2013,"cited_by_count":20},{"year":2012,"cited_by_count":9}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}