{"id":"https://openalex.org/W204501698","doi":null,"title":"Neuroendocrine structures in normal and diseased human lung.","display_name":"Neuroendocrine structures in normal and diseased human lung.","publication_year":1986,"publication_date":"1986-01-01","ids":{"openalex":"https://openalex.org/W204501698","mag":"204501698","pmid":"https://pubmed.ncbi.nlm.nih.gov/3036186"},"language":"en","primary_location":{"id":"pmid:3036186","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3036186","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Applied pathology","raw_type":"Journal Article"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102942155","display_name":"L Mosca","orcid":"https://orcid.org/0000-0003-2622-4195","observed_orcids":["https://orcid.org/0000-0003-2622-4195"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L Mosca","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038240423","display_name":"A Ceresoli","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Ceresoli","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045141694","display_name":"E Anzanello","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E Anzanello","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"F Mauri","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F Mauri","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028662519","display_name":"Cesare Mariscotti","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C Mariscotti","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073483777","display_name":"R. Timossi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Timossi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081257602","display_name":"Mattia Barbareschi","orcid":"https://orcid.org/0000-0003-0217-3223","observed_orcids":["https://orcid.org/0000-0003-0217-3223"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Barbareschi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5079242394","display_name":"Maura Mezzetti","orcid":"https://orcid.org/0000-0002-8214-7000","observed_orcids":["https://orcid.org/0000-0002-8214-7000"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Mezzetti","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1141,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.77540416,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"4","issue":"3","first_page":"147","last_page":"61"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10754","display_name":"Neuroendocrine Tumor Research Advances","score":0.8300999999046326,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10754","display_name":"Neuroendocrine Tumor Research Advances","score":0.8300999999046326,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12334","display_name":"Lung Cancer Research Studies","score":0.15530000627040863,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12992","display_name":"Metastasis and carcinoma case studies","score":0.004699999932199717,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuroendocrine-carcinoma","display_name":"neuroendocrine carcinoma","score":0.777999997138977},{"id":"https://openalex.org/keywords/lung","display_name":"lung","score":0.34200000762939453},{"id":"https://openalex.org/keywords/neuroendocrine-cells","display_name":"neuroendocrine cells","score":0.8550000190734863},{"id":"https://openalex.org/keywords/neuroepithelial-bodies","display_name":"neuroepithelial bodies","score":0.9449999928474426},{"id":"https://openalex.org/keywords/typical-carcinoid","display_name":"typical carcinoid","score":0.75},{"id":"https://openalex.org/keywords/small-cell-carcinoma","display_name":"small cell carcinoma","score":0.6299999952316284},{"id":"https://openalex.org/keywords/classification","display_name":"classification","score":0.32199999690055847},{"id":"https://openalex.org/keywords/dysplasia","display_name":"dysplasia","score":0.7820000052452087},{"id":"https://openalex.org/keywords/hyperplasia","display_name":"hyperplasia","score":0.7599999904632568},{"id":"https://openalex.org/keywords/lung-cancer-histology","display_name":"lung cancer histology","score":0.49900001287460327}],"concepts":[{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.8149716854095459},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.665949821472168},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.5264768600463867},{"id":"https://openalex.org/C2777562237","wikidata":"https://www.wikidata.org/wiki/Q835051","display_name":"Hyperplasia","level":2,"score":0.5190578103065491},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.4582068920135498},{"id":"https://openalex.org/C2779066768","wikidata":"https://www.wikidata.org/wiki/Q1981276","display_name":"Neuroendocrine tumors","level":2,"score":0.4553629755973816},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4511222243309021},{"id":"https://openalex.org/C2777858994","wikidata":"https://www.wikidata.org/wiki/Q10599959","display_name":"Neuroendocrine cell","level":3,"score":0.41469791531562805},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3321712017059326},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17537125945091248}],"mesh":[{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002276","descriptor_name":"Carcinoid Tumor","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009490","descriptor_name":"Neurosecretory Systems","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D018288","descriptor_name":"Carcinoma, Small Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:3036186","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3036186","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Applied pathology","raw_type":"Journal Article"},{"id":"mag:204501698","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3036186","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W109279539","https://openalex.org/W2024116896","https://openalex.org/W2131325554","https://openalex.org/W2059805364","https://openalex.org/W3011801481","https://openalex.org/W3197403984","https://openalex.org/W35906709","https://openalex.org/W7167273889","https://openalex.org/W1880086995","https://openalex.org/W1983866333"],"abstract_inverted_index":{"The":[0,30],"increasing":[1],"amount":[2],"of":[3,24,32,54,91,112,120,134,143],"histological,":[4],"immunohistochemical":[5],"and":[6,74,94,106,141],"ultrastructural":[7],"information":[8],"on":[9,27,37],"some":[10],"endocrine":[11],"secretions":[12],"in":[13],"human":[14],"lung":[15,38,56],"cancers":[16],"suggest":[17],"the":[18,22,33,89,110,117],"need":[19],"to":[20,43,47,104],"revise":[21],"classification":[23,53,119],"neuroendocrine":[25,55,72,92,121],"lesions":[26],"surgical":[28],"material.":[29],"aim":[31],"present":[34],"investigation":[35],"based":[36],"specimens":[39],"removed":[40],"surgically":[41],"is":[42],"give":[44],"further":[45],"support":[46],"recent":[48],"proposal":[49],"for":[50],"an":[51],"updated":[52],"carcinomas.":[57],"Our":[58],"study":[59],"includes":[60],"58":[61,65],"squamous":[62],"cell":[63,69],"carcinomas,":[64,70,73],"adenocarcinomas,":[66],"6":[67],"large":[68],"27":[71],"30":[75],"nontumourous":[76],"cases.":[77],"Using":[78],"histological":[79],"methods":[80],"(HE,":[81],"Alcian":[82],"PAS,":[83],"Grimelius":[84],"silver":[85],"impregnation),":[86],"we":[87,115],"illustrate":[88],"presence":[90],"cells":[93],"neuroepithelial":[95],"bodies":[96],"with":[97],"their":[98],"pathological":[99],"evolutions,":[100],"ranging":[101],"from":[102],"hyperplasia,":[103],"dysplasia,":[105],"overt":[107],"neoplasia.":[108],"On":[109],"basis":[111],"our":[113],"experience":[114],"propose":[116],"following":[118],"carcinomas":[122],"(NEC):":[123],"typical":[124],"carcinoids":[125],"(NECNID),":[126],"peripheral":[127],"carcinoid":[128],"or":[129,136,146],"well-differentiated":[130],"NEC":[131,133,142],"(NECWED),":[132],"intermediate":[135],"poorly":[137],"differentiated":[138],"type":[139,148],"(NECINT)":[140],"small":[144],"celled":[145],"microcytoma":[147],"(NECMIC).":[149]},"counts_by_year":[{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}