{"id":"https://openalex.org/W2044909682","doi":"https://doi.org/10.1120/1.1288713","title":"Fast verification of Gamma Knife\u2122 treatment plans","display_name":"Fast verification of Gamma Knife\u2122 treatment plans","publication_year":2000,"publication_date":"2000-09-01","ids":{"openalex":"https://openalex.org/W2044909682","doi":"https://doi.org/10.1120/1.1288713","mag":"2044909682","pmid":"https://pubmed.ncbi.nlm.nih.gov/11674832","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5726158"},"language":"en","primary_location":{"id":"doi:10.1120/1.1288713","doi":"https://doi.org/10.1120/1.1288713","is_oa":true,"landing_page_url":"https://doi.org/10.1120/1.1288713","pdf_url":null,"source":{"id":"https://openalex.org/S29972171","display_name":"Journal of Applied Clinical Medical Physics","issn_l":"1526-9914","issn":["1526-9914"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Applied Clinical Medical Physics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1120/1.1288713","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100684255","display_name":"Pengpeng Zhang","orcid":"https://orcid.org/0000-0003-2622-9367","observed_orcids":["https://orcid.org/0000-0003-2622-9367"]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Pengpeng Zhang","raw_affiliation_strings":["Department of Biomedical Engineering Case Western Reserve University  Cleveland Ohio 44106","Department of Biomedical Engineering Case Western Reserve University Cleveland Ohio 44106 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering Case Western Reserve University  Cleveland Ohio 44106","institution_ids":["https://openalex.org/I58956616"]},{"raw_affiliation_string":"Department of Biomedical Engineering Case Western Reserve University Cleveland Ohio 44106 USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054441753","display_name":"David Dean","orcid":"https://orcid.org/0000-0002-1217-3764","observed_orcids":["https://orcid.org/0000-0002-1217-3764"]},"institutions":[{"id":"https://openalex.org/I2799343972","display_name":"University Hospitals of Cleveland","ror":"https://ror.org/0130jk839","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"David Dean","raw_affiliation_strings":["Department of Neurological Surgery University Hospitals of Cleveland/Case Western Reserve University  Cleveland Ohio 44106","Neurosurgery"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurological Surgery University Hospitals of Cleveland/Case Western Reserve University  Cleveland Ohio 44106","institution_ids":["https://openalex.org/I2799343972","https://openalex.org/I58956616"]},{"raw_affiliation_string":"Neurosurgery","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069570157","display_name":"Qiuwen Wu","orcid":"https://orcid.org/0000-0003-0748-7280","observed_orcids":["https://orcid.org/0000-0003-0748-7280"]},"institutions":[{"id":"https://openalex.org/I2799343972","display_name":"University Hospitals of Cleveland","ror":"https://ror.org/0130jk839","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Q. Jackie Wu","raw_affiliation_strings":["Department of Radiation Oncology University Hospitals of Cleveland/Case Western Reserve University Cleveland Ohio 44106"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Hospitals of Cleveland/Case Western Reserve University Cleveland Ohio 44106","institution_ids":["https://openalex.org/I2799343972","https://openalex.org/I58956616"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071365207","display_name":"Cl\u00e1udio H. Sibata","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799343972","display_name":"University Hospitals of Cleveland","ror":"https://ror.org/0130jk839","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Claudio Sibata","raw_affiliation_strings":["Department of Radiation Oncology University Hospitals of Cleveland/Case Western Reserve University Cleveland Ohio 44106"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology University Hospitals of Cleveland/Case Western Reserve University Cleveland Ohio 44106","institution_ids":["https://openalex.org/I2799343972","https://openalex.org/I58956616"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5054441753","https://openalex.org/A5069570157","https://openalex.org/A5071365207","https://openalex.org/A5100684255"],"corresponding_institution_ids":["https://openalex.org/I2799343972","https://openalex.org/I58956616"],"apc_list":{"value":900,"currency":"USD","value_usd":900},"apc_paid":{"value":900,"currency":"USD","value_usd":900},"fwci":1.4234,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.80171406,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"1","issue":"4","first_page":"158","last_page":"158"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11949","display_name":"Nuclear Physics and Applications","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gamma-knife-radiosurgery","display_name":"gamma knife radiosurgery","score":0.8610000014305115},{"id":"https://openalex.org/keywords/treatment-plan-verification","display_name":"treatment plan verification","score":0.9169999957084656},{"id":"https://openalex.org/keywords/irradiation-time","display_name":"irradiation time","score":0.7879999876022339},{"id":"https://openalex.org/keywords/tissue-maximum-ratio","display_name":"tissue maximum ratio","score":0.9819999933242798},{"id":"https://openalex.org/keywords/stereotactic-frame","display_name":"stereotactic frame","score":0.8769999742507935},{"id":"https://openalex.org/keywords/head-model","display_name":"human head model","score":0.6600000262260437},{"id":"https://openalex.org/keywords/linear-interpolation","display_name":"linear interpolation","score":0.5559999942779541}],"concepts":[{"id":"https://openalex.org/C181401712","wikidata":"https://www.wikidata.org/wiki/Q6085394","display_name":"Isocenter","level":3,"score":0.9582582712173462},{"id":"https://openalex.org/C2779200277","wikidata":"https://www.wikidata.org/wiki/Q1164658","display_name":"Collimator","level":2,"score":0.853918194770813},{"id":"https://openalex.org/C2780387249","wikidata":"https://www.wikidata.org/wiki/Q973234","display_name":"Radiosurgery","level":3,"score":0.7334837317466736},{"id":"https://openalex.org/C104293457","wikidata":"https://www.wikidata.org/wiki/Q28324852","display_name":"Imaging phantom","level":2,"score":0.6873869895935059},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.47603750228881836},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.4565048813819885},{"id":"https://openalex.org/C16038011","wikidata":"https://www.wikidata.org/wiki/Q62912","display_name":"Cartesian coordinate system","level":2,"score":0.4411516785621643},{"id":"https://openalex.org/C201645570","wikidata":"https://www.wikidata.org/wiki/Q830637","display_name":"Radiation treatment planning","level":3,"score":0.43893879652023315},{"id":"https://openalex.org/C137800194","wikidata":"https://www.wikidata.org/wiki/Q11713455","display_name":"Interpolation (computer graphics)","level":3,"score":0.429617702960968},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.42938193678855896},{"id":"https://openalex.org/C168834538","wikidata":"https://www.wikidata.org/wiki/Q3705329","display_name":"Beam (structure)","level":2,"score":0.4152419865131378},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.401703417301178},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3554324507713318},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.20404109358787537},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.16981583833694458},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.1678008735179901},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11075448989868164},{"id":"https://openalex.org/C104114177","wikidata":"https://www.wikidata.org/wiki/Q79782","display_name":"Motion (physics)","level":2,"score":0.0},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011880","descriptor_name":"Radiotherapy Planning, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012886","descriptor_name":"Skull","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016634","descriptor_name":"Radiosurgery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1120/1.1288713","doi":"https://doi.org/10.1120/1.1288713","is_oa":true,"landing_page_url":"https://doi.org/10.1120/1.1288713","pdf_url":null,"source":{"id":"https://openalex.org/S29972171","display_name":"Journal of Applied Clinical Medical Physics","issn_l":"1526-9914","issn":["1526-9914"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Applied Clinical Medical Physics","raw_type":"journal-article"},{"id":"doi:10.1120/jacmp.v1i4.2638","doi":"https://doi.org/10.1120/jacmp.v1i4.2638","is_oa":true,"landing_page_url":"https://doi.org/10.1120/jacmp.v1i4.2638","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1120/jacmp.v1i4.2638","source":{"id":"https://openalex.org/S29972171","display_name":"Journal of Applied Clinical Medical Physics","issn_l":"1526-9914","issn":["1526-9914"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Applied Clinical Medical Physics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5726158","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5726158","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Appl Clin Med Phys","raw_type":"Text"},{"id":"pmid:11674832","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11674832","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of applied clinical medical physics","raw_type":"Comparative Study"}],"best_oa_location":{"id":"doi:10.1120/1.1288713","doi":"https://doi.org/10.1120/1.1288713","is_oa":true,"landing_page_url":"https://doi.org/10.1120/1.1288713","pdf_url":null,"source":{"id":"https://openalex.org/S29972171","display_name":"Journal of Applied Clinical Medical Physics","issn_l":"1526-9914","issn":["1526-9914"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Applied Clinical Medical Physics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.4043000042438507}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5600000023841858}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":4,"referenced_works":["https://openalex.org/W2057428339","https://openalex.org/W2072508467","https://openalex.org/W2123811698","https://openalex.org/W2163205596"],"related_works":["https://openalex.org/W2033343509","https://openalex.org/W2122518848","https://openalex.org/W2035520590","https://openalex.org/W2026245889","https://openalex.org/W1743442017","https://openalex.org/W1821612912","https://openalex.org/W1969430796","https://openalex.org/W2060298156","https://openalex.org/W2077068217","https://openalex.org/W2595589395"],"abstract_inverted_index":{"The":[0,88,183,200,239],"Leksell":[1,51],"stereotactic":[2,111],"Gamma":[3,52,104],"Knifetrade":[4,53,105],"mark":[5,54,106],"uses":[6],"radiation":[7,28],"from":[8],"201":[9,86],"(60)Co":[10],"sources":[11],"that":[12,185],"are":[13,176,241],"focused":[14],"to":[15,22,120,140,164,192,229,243],"the":[16,44,50,61,68,76,84,96,99,103,110,126,132,135,141,150,154,161,171,180,189,193,209,212,231],"center":[17],"of":[18,27,32,43,83,98,115,134,146],"a":[19,24,38,122,219],"collimator":[20,107,136],"helmet":[21,108,137],"deliver":[23],"high":[25],"dose":[26],"with":[29,95,208,245],"minimal":[30],"irradiation":[31,45,62],"proximal":[33],"structures.":[34],"This":[35,225],"paper":[36,93],"presents":[37],"method":[39],"for":[40,64,81,202,211],"fast":[41],"verification":[42],"time":[46,63,233],"as":[47],"calculated":[48,234],"by":[49,159,178],"treatment":[55,69,232],"planning":[56],"software":[57],"GammaPlan((R)).":[58],"To":[59],"obtain":[60],"each":[65,82,168,186,203],"shot":[66,142],"in":[67,91,235],"plan,":[70],"one":[71],"must":[72],"first":[73],"accurately":[74],"calculate":[75],"tissue":[77],"maximum":[78],"ratio":[79],"(TMR)":[80],"individual":[85,169],"beams.":[87],"algorithm":[89,226],"presented":[90],"this":[92],"begins":[94],"determination":[97],"geometrical":[100],"relationship":[101],"between":[102],"and":[109],"frame.":[112],"A":[113,144],"group":[114,145],"reference":[116,151,174],"points":[117,152],"is":[118,138,157,195,206,216,227],"measured":[119],"build":[121],"head":[123],"model":[124],"simulating":[125],"patient":[127],"skull":[128,155,191],"geometry.":[129],"During":[130],"radiosurgery,":[131],"isocenter":[133,194],"moved":[139],"center.":[143],"spatial":[147],"vectors":[148,175],"describing":[149],"at":[153],"surface":[156],"obtained":[158,196],"converting":[160],"Cartesian":[162],"coordinates":[163],"Polar":[165],"coordinates.":[166],"For":[167],"beam,":[170],"three":[172],"nearest":[173],"found":[177],"ranking":[179],"relative":[181],"angles.":[182],"depth":[184],"beam":[187,204],"penetrates":[188],"patient's":[190],"via":[197],"linear":[198],"interpolation.":[199],"TMR":[201,210],"then":[205],"compared":[207],"calibration":[213],"setup,":[214],"which":[215],"done":[217],"using":[218],"spherical":[220],"8":[221],"cm":[222],"radius":[223],"phantom.":[224],"applied":[228],"verify":[230],"GammaPlan((R))":[236,246],"Version":[237],"5.2.":[238],"results":[240],"shown":[242],"agree":[244],"within":[247],"3%.":[248]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}