{"id":"https://openalex.org/W2044860892","doi":"https://doi.org/10.1089/dia.2011.0089","title":"Measurement of Glucose Area Under the Curve Using Minimally Invasive Interstitial Fluid Extraction Technology: Evaluation of Glucose Monitoring Concepts Without Blood Sampling","display_name":"Measurement of Glucose Area Under the Curve Using Minimally Invasive Interstitial Fluid Extraction Technology: Evaluation of Glucose Monitoring Concepts Without Blood Sampling","publication_year":2011,"publication_date":"2011-07-19","ids":{"openalex":"https://openalex.org/W2044860892","doi":"https://doi.org/10.1089/dia.2011.0089","mag":"2044860892","pmid":"https://pubmed.ncbi.nlm.nih.gov/21770766"},"language":"en","primary_location":{"id":"doi:10.1089/dia.2011.0089","doi":"https://doi.org/10.1089/dia.2011.0089","is_oa":false,"landing_page_url":"https://doi.org/10.1089/dia.2011.0089","pdf_url":null,"source":{"id":"https://openalex.org/S67495602","display_name":"Diabetes Technology & Therapeutics","issn_l":"1520-9156","issn":["1520-9156","1557-8593"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-2","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Technology & Therapeutics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103091662","display_name":"Toshiyuki Sato","orcid":"https://orcid.org/0000-0002-4515-4201","observed_orcids":["https://orcid.org/0000-0002-4515-4201","https://orcid.org/0009-0009-5460-2625"]},"institutions":[{"id":"https://openalex.org/I54594937","display_name":"Sysmex (Japan)","ror":"https://ror.org/00gfstq19","country_code":"JP","type":"company","lineage":["https://openalex.org/I54594937"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Toshiyuki Sato","raw_affiliation_strings":["Central Research Laboratories","Central Research Laboratories, Sysmex Corporation, Kobe, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Research Laboratories","institution_ids":[]},{"raw_affiliation_string":"Central Research Laboratories, Sysmex Corporation, Kobe, Japan","institution_ids":["https://openalex.org/I54594937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006854138","display_name":"Seiki Okada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I54594937","display_name":"Sysmex (Japan)","ror":"https://ror.org/00gfstq19","country_code":"JP","type":"company","lineage":["https://openalex.org/I54594937"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Seiki Okada","raw_affiliation_strings":["Central Research Laboratories","Central Research Laboratories, Sysmex Corporation, Kobe, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Research Laboratories","institution_ids":[]},{"raw_affiliation_string":"Central Research Laboratories, Sysmex Corporation, Kobe, Japan","institution_ids":["https://openalex.org/I54594937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052978967","display_name":"Kei Hagino","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I54594937","display_name":"Sysmex (Japan)","ror":"https://ror.org/00gfstq19","country_code":"JP","type":"company","lineage":["https://openalex.org/I54594937"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kei Hagino","raw_affiliation_strings":["Central Research Laboratories","Central Research Laboratories, Sysmex Corporation, Kobe, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Research Laboratories","institution_ids":[]},{"raw_affiliation_string":"Central Research Laboratories, Sysmex Corporation, Kobe, Japan","institution_ids":["https://openalex.org/I54594937"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yoshihiro Asakura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I54594937","display_name":"Sysmex (Japan)","ror":"https://ror.org/00gfstq19","country_code":"JP","type":"company","lineage":["https://openalex.org/I54594937"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshihiro Asakura","raw_affiliation_strings":["Central Research Laboratories","Central Research Laboratories, Sysmex Corporation, Kobe, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Research Laboratories","institution_ids":[]},{"raw_affiliation_string":"Central Research Laboratories, Sysmex Corporation, Kobe, Japan","institution_ids":["https://openalex.org/I54594937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056821697","display_name":"Yasuo Kikkawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I54594937","display_name":"Sysmex (Japan)","ror":"https://ror.org/00gfstq19","country_code":"JP","type":"company","lineage":["https://openalex.org/I54594937"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasuo Kikkawa","raw_affiliation_strings":["Central Research Laboratories","Central Research Laboratories, Sysmex Corporation, Kobe, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Research Laboratories","institution_ids":[]},{"raw_affiliation_string":"Central Research Laboratories, Sysmex Corporation, Kobe, Japan","institution_ids":["https://openalex.org/I54594937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029134506","display_name":"Junko Kojima","orcid":"https://orcid.org/0000-0003-1928-6275","observed_orcids":["https://orcid.org/0000-0003-1928-6275"]},"institutions":[{"id":"https://openalex.org/I54594937","display_name":"Sysmex (Japan)","ror":"https://ror.org/00gfstq19","country_code":"JP","type":"company","lineage":["https://openalex.org/I54594937"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Junko Kojima","raw_affiliation_strings":["Central Research Laboratories","Central Research Laboratories, Sysmex Corporation, Kobe, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Research Laboratories","institution_ids":[]},{"raw_affiliation_string":"Central Research Laboratories, Sysmex Corporation, Kobe, Japan","institution_ids":["https://openalex.org/I54594937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103353529","display_name":"Toshihiro Watanabe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I54594937","display_name":"Sysmex (Japan)","ror":"https://ror.org/00gfstq19","country_code":"JP","type":"company","lineage":["https://openalex.org/I54594937"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshihiro Watanabe","raw_affiliation_strings":["Central Research Laboratories","Central Research Laboratories, Sysmex Corporation, Kobe, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Research Laboratories","institution_ids":[]},{"raw_affiliation_string":"Central Research Laboratories, Sysmex Corporation, Kobe, Japan","institution_ids":["https://openalex.org/I54594937"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yasunori Maekawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I54594937","display_name":"Sysmex (Japan)","ror":"https://ror.org/00gfstq19","country_code":"JP","type":"company","lineage":["https://openalex.org/I54594937"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasunori Maekawa","raw_affiliation_strings":["Central Research Laboratories","Central Research Laboratories, Sysmex Corporation, Kobe, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Research Laboratories","institution_ids":[]},{"raw_affiliation_string":"Central Research Laboratories, Sysmex Corporation, Kobe, Japan","institution_ids":["https://openalex.org/I54594937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049414867","display_name":"Kazuki Isobe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405265001","display_name":"Nichiban Co., Ltd. (Japan)","ror":"https://ror.org/03jgr6c36","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405265001"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuki Isobe","raw_affiliation_strings":["Medical Products Development Center","Medical Products Development Center, Nichiban Co. Ltd., Fukuoka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Products Development Center","institution_ids":[]},{"raw_affiliation_string":"Medical Products Development Center, Nichiban Co. Ltd., Fukuoka, Japan","institution_ids":["https://openalex.org/I4405265001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009164981","display_name":"Reona Koike","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405265001","display_name":"Nichiban Co., Ltd. (Japan)","ror":"https://ror.org/03jgr6c36","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405265001"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Reona Koike","raw_affiliation_strings":["Medical Products Development Center","Medical Products Development Center, Nichiban Co. Ltd., Fukuoka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Products Development Center","institution_ids":[]},{"raw_affiliation_string":"Medical Products Development Center, Nichiban Co. Ltd., Fukuoka, Japan","institution_ids":["https://openalex.org/I4405265001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103408611","display_name":"Hiromu Nakajima","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210151107","display_name":"Osaka International Cancer Institute","ror":"https://ror.org/05xvwhv53","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210151107","https://openalex.org/I4405282797"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiromu Nakajima","raw_affiliation_strings":["Osaka Medical Center for Cancer and Cardiovascular Diseases","Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Osaka Medical Center for Cancer and Cardiovascular Diseases","institution_ids":["https://openalex.org/I4210151107"]},{"raw_affiliation_string":"Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan","institution_ids":["https://openalex.org/I4210151107"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031843776","display_name":"Kaoru Asano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I54594937","display_name":"Sysmex (Japan)","ror":"https://ror.org/00gfstq19","country_code":"JP","type":"company","lineage":["https://openalex.org/I54594937"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kaoru Asano","raw_affiliation_strings":["Central Research Laboratories","Central Research Laboratories, Sysmex Corporation, Kobe, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Research Laboratories","institution_ids":[]},{"raw_affiliation_string":"Central Research Laboratories, Sysmex Corporation, Kobe, Japan","institution_ids":["https://openalex.org/I54594937"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5103091662"],"corresponding_institution_ids":["https://openalex.org/I54594937"],"apc_list":null,"apc_paid":null,"fwci":2.2595,"has_fulltext":false,"cited_by_count":38,"citation_normalized_percentile":{"value":0.87121556,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"13","issue":"12","first_page":"1194","last_page":"1200"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12433","display_name":"Skin Diseases and Diabetes","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interstitial-glucose","display_name":"interstitial glucose","score":0.8539999723434448},{"id":"https://openalex.org/keywords/glucose-area-under-the-curve","display_name":"glucose area under the curve","score":0.9679999947547913},{"id":"https://openalex.org/keywords/minimally-invasive-glucose-monitoring","display_name":"minimally invasive glucose monitoring","score":0.8600000143051147},{"id":"https://openalex.org/keywords/postprandial-hyperglycemia","display_name":"postprandial hyperglycemia","score":0.8659999966621399},{"id":"https://openalex.org/keywords/microneedles","display_name":"microneedles","score":0.8569999933242798},{"id":"https://openalex.org/keywords/blood-glucose","display_name":"blood glucose","score":0.4090000092983246},{"id":"https://openalex.org/keywords/diabetes-monitoring","display_name":"diabetes monitoring","score":0.7509999871253967},{"id":"https://openalex.org/keywords/non-invasive-glucose-measurement","display_name":"non-invasive glucose measurement","score":0.6299999952316284}],"concepts":[{"id":"https://openalex.org/C2778199505","wikidata":"https://www.wikidata.org/wiki/Q2992990","display_name":"Postprandial","level":3,"score":0.9377024173736572},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7626661062240601},{"id":"https://openalex.org/C76318530","wikidata":"https://www.wikidata.org/wiki/Q16833590","display_name":"Area under the curve","level":2,"score":0.6541522741317749},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5921422243118286},{"id":"https://openalex.org/C2988731192","wikidata":"https://www.wikidata.org/wiki/Q7410159","display_name":"Blood sampling","level":2,"score":0.5845460891723633},{"id":"https://openalex.org/C2779822359","wikidata":"https://www.wikidata.org/wiki/Q2914458","display_name":"Interstitial fluid","level":2,"score":0.5334532260894775},{"id":"https://openalex.org/C537181965","wikidata":"https://www.wikidata.org/wiki/Q658","display_name":"Sodium","level":2,"score":0.4499257802963257},{"id":"https://openalex.org/C2779524580","wikidata":"https://www.wikidata.org/wiki/Q4927806","display_name":"Blood glucose monitoring","level":3,"score":0.447104275226593},{"id":"https://openalex.org/C23531484","wikidata":"https://www.wikidata.org/wiki/Q3196863","display_name":"Calibration curve","level":3,"score":0.4334811568260193},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.42188069224357605},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.3478107452392578},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3456048369407654},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.2937043309211731},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.14462175965309143},{"id":"https://openalex.org/C119128265","wikidata":"https://www.wikidata.org/wiki/Q900165","display_name":"Detection limit","level":2,"score":0.121816486120224},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D003920","descriptor_name":"Diabetes Mellitus","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003920","descriptor_name":"Diabetes Mellitus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005947","descriptor_name":"Glucose","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D005947","descriptor_name":"Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008991","descriptor_name":"Monitoring, Physiologic","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D008991","descriptor_name":"Monitoring, Physiologic","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D012964","descriptor_name":"Sodium","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D019518","descriptor_name":"Postprandial Period","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019540","descriptor_name":"Area Under Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045604","descriptor_name":"Extracellular Fluid","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1089/dia.2011.0089","doi":"https://doi.org/10.1089/dia.2011.0089","is_oa":false,"landing_page_url":"https://doi.org/10.1089/dia.2011.0089","pdf_url":null,"source":{"id":"https://openalex.org/S67495602","display_name":"Diabetes Technology & Therapeutics","issn_l":"1520-9156","issn":["1520-9156","1557-8593"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-2","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Technology & Therapeutics","raw_type":"journal-article"},{"id":"pmid:21770766","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21770766","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes technology & therapeutics","raw_type":"Evaluation Study"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322252","display_name":"Israel Science Foundation","ror":"https://ror.org/04sazxf24"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1911689053","https://openalex.org/W1974433810","https://openalex.org/W1983078009","https://openalex.org/W2003735777","https://openalex.org/W2004112557","https://openalex.org/W2006086487","https://openalex.org/W2010464045","https://openalex.org/W2011486475","https://openalex.org/W2034924100","https://openalex.org/W2048907716","https://openalex.org/W2061958341","https://openalex.org/W2117369764","https://openalex.org/W2137563174","https://openalex.org/W2139536521","https://openalex.org/W2234545288"],"related_works":["https://openalex.org/W2075569025","https://openalex.org/W2753660744","https://openalex.org/W1973756806","https://openalex.org/W2507320913","https://openalex.org/W2116321774","https://openalex.org/W2089380970","https://openalex.org/W1626349474","https://openalex.org/W2012144097","https://openalex.org/W2007862827","https://openalex.org/W1964063750"],"abstract_inverted_index":{"BACKGROUND:":[0],"Monitoring":[1,230],"postprandial":[2,23],"hyperglycemia":[3,24],"is":[4,178,198],"crucial":[5],"in":[6,68,108,126,153,187],"treating":[7],"diabetes,":[8],"although":[9],"its":[10],"dynamics":[11],"make":[12],"accurate":[13],"monitoring":[14,22],"difficult.":[15],"We":[16],"developed":[17],"a":[18,88,94,151,179,207,216],"new":[19],"technology":[20,30,76],"for":[21,183,202],"using":[25,41,104,228,232],"interstitial":[26],"fluid":[27],"(ISF)":[28],"extraction":[29,75],"without":[31,234],"blood":[32,113,235],"sampling.":[33],"The":[34,57,96,185],"glucose":[35,49,99,114,141,163,225,231],"area":[36],"under":[37],"the":[38,138,222],"curve":[39],"(AUC)":[40],"this":[42,60,65],"system":[43],"was":[44,62,106,135,146,160,193],"measured":[45],"as":[46],"accumulated":[47],"ISF":[48,74,85],"(IG)":[50],"with":[51,54,82,93,111,191,242],"simultaneous":[52],"calibration":[53],"sodium":[55,101,165,176],"ions.":[56],"objective":[58],"of":[59,140,224],"study":[61],"to":[63,129,240],"evaluate":[64],"technological":[66],"concept":[67],"healthy":[69],"individuals.":[70],"METHODS:":[71],"Minimally":[72],"invasive":[73],"(MIET)":[77],"comprises":[78],"two":[79],"steps:":[80],"pretreatment":[81],"microneedles":[83],"and":[84,100,120,164,189,213],"accumulation":[86],"over":[87],"specific":[89],"time":[90,122],"by":[91,144],"contact":[92],"solvent.":[95],"correlation":[97,159,209],"between":[98,162,211],"ion":[102,166,177],"levels":[103,116,167,170],"MIET":[105,145,192,233],"evaluated":[107,125,147],"12":[109],"subjects":[110,128],"stable":[112,172],"(BG)":[115],"during":[117],"fasting.":[118],"BG":[119,134,169,190],"IG":[121,188,197],"courses":[123],"were":[124,171],"three":[127],"confirm":[130],"their":[131],"relationship":[132],"while":[133],"fluctuating.":[136],"Furthermore,":[137],"accuracy":[139],"AUC":[142,226],"measurements":[143,227],"several":[148],"hours":[149],"after":[150,215],"meal":[152],"30":[154],"subjects.":[155],"RESULTS:":[156],"A":[157],"high":[158],"observed":[161],"when":[168],"(R=0.87),":[173],"indicating":[174,195],"that":[175,196],"good":[180],"internal":[181],"standard":[182],"calibration.":[184],"variation":[186],"similar,":[194],"an":[199],"adequate":[200],"substitute":[201],"BG.":[203],"Finally,":[204],"we":[205],"showed":[206],"strong":[208],"(R=0.92)":[210],"IG-AUC":[212],"BG-AUC":[214],"meal.":[217],"CONCLUSIONS:":[218],"These":[219],"findings":[220],"validate":[221],"adequacy":[223],"MIET.":[229],"sampling":[236],"may":[237],"be":[238],"beneficial":[239],"patients":[241],"diabetes.":[243]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}