{"id":"https://openalex.org/W2044729253","doi":"https://doi.org/10.1111/j.1699-0463.1977.tb03619.x","title":"PSEUDOMONAS AERUGINOSA INFECTION IN CYSTIC FIBROSIS:","display_name":"PSEUDOMONAS AERUGINOSA INFECTION IN CYSTIC FIBROSIS:","publication_year":1977,"publication_date":"1977-05-01","ids":{"openalex":"https://openalex.org/W2044729253","doi":"https://doi.org/10.1111/j.1699-0463.1977.tb03619.x","mag":"2044729253","pmid":"https://pubmed.ncbi.nlm.nih.gov/404841"},"language":"en","primary_location":{"id":"doi:10.1111/j.1699-0463.1977.tb03619.x","doi":"https://doi.org/10.1111/j.1699-0463.1977.tb03619.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1699-0463.1977.tb03619.x","pdf_url":null,"source":{"id":"https://openalex.org/S4210228615","display_name":"Acta Pathologica Microbiologica Scandinavica Section C Immunology","issn_l":"0108-0202","issn":["0108-0202","0304-1328"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Pathologica Microbiologica Scandinavica Section C Immunology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086191926","display_name":"Niels H\u00f8iby","orcid":"https://orcid.org/0000-0002-1347-725X","observed_orcids":["https://orcid.org/0000-0002-1347-725X"]},"institutions":[{"id":"https://openalex.org/I101527212","display_name":"Statens Serum Institut","ror":"https://ror.org/0417ye583","country_code":"DK","type":"facility","lineage":["https://openalex.org/I101527212"]},{"id":"https://openalex.org/I2801942218","display_name":"Hvidovre Hospital","ror":"https://ror.org/00edrn755","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801942218","https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Niels H\u00d8iby","raw_affiliation_strings":["Statens Seruminstitut, Department of Clinical Microbiology at K\u00f8benhavns Kommunes Hospital i Hvidovre, and the Paediatric Clinic TG, Rigshospitalet, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Statens Seruminstitut, Department of Clinical Microbiology at K\u00f8benhavns Kommunes Hospital i Hvidovre, and the Paediatric Clinic TG, Rigshospitalet, Copenhagen, Denmark","institution_ids":["https://openalex.org/I101527212","https://openalex.org/I2801942218","https://openalex.org/I2802709434"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023634754","display_name":"Sante Olling","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I881427289","display_name":"University of Gothenburg","ror":"https://ror.org/01tm6cn81","country_code":"SE","type":"education","lineage":["https://openalex.org/I881427289"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Sante Olling","raw_affiliation_strings":["Department of Immunology, Institute of Medical Microbiology and Institute of Pathology II, University of Go\u0308teborg, Go\u0308teborg, Sweden","Department of Immunology, Institute of Medical Microbiology and Institute of Pathology II, University of G\u00f6teborg, G\u00f6teborg, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Institute of Medical Microbiology and Institute of Pathology II, University of Go\u0308teborg, Go\u0308teborg, Sweden","institution_ids":["https://openalex.org/I881427289"]},{"raw_affiliation_string":"Department of Immunology, Institute of Medical Microbiology and Institute of Pathology II, University of G\u00f6teborg, G\u00f6teborg, Sweden","institution_ids":["https://openalex.org/I881427289"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5023634754"],"corresponding_institution_ids":["https://openalex.org/I881427289"],"apc_list":null,"apc_paid":null,"fwci":5.3229,"has_fulltext":false,"cited_by_count":96,"citation_normalized_percentile":{"value":0.94443704,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"85C","issue":"2","first_page":"107","last_page":"114"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":0.9067000150680542,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":0.9067000150680542,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.0771000012755394,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12824","display_name":"Infections and bacterial resistance","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pseudomonas-aeruginosa","display_name":"Pseudomonas aeruginosa","score":1.0},{"id":"https://openalex.org/keywords/cystic-fibrosis","display_name":"cystic fibrosis","score":1.0},{"id":"https://openalex.org/keywords/bactericidal-activity","display_name":"bactericidal activity","score":0.7089999914169312},{"id":"https://openalex.org/keywords/human-serum","display_name":"human serum","score":0.8769999742507935},{"id":"https://openalex.org/keywords/serum-sensitivity","display_name":"serum sensitivity","score":0.6819999814033508},{"id":"https://openalex.org/keywords/precipitating-antibodies","display_name":"precipitating antibodies","score":0.6869999766349792},{"id":"https://openalex.org/keywords/chronic-infection","display_name":"chronic infection","score":0.6169999837875366}],"concepts":[{"id":"https://openalex.org/C2777637488","wikidata":"https://www.wikidata.org/wiki/Q31856","display_name":"Pseudomonas aeruginosa","level":3,"score":0.9245571494102478},{"id":"https://openalex.org/C133229898","wikidata":"https://www.wikidata.org/wiki/Q7239484","display_name":"Precipitin","level":3,"score":0.8447211980819702},{"id":"https://openalex.org/C2776938444","wikidata":"https://www.wikidata.org/wiki/Q178194","display_name":"Cystic fibrosis","level":2,"score":0.8321493864059448},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.7247087955474854},{"id":"https://openalex.org/C2779644171","wikidata":"https://www.wikidata.org/wiki/Q13400765","display_name":"Respiratory tract","level":3,"score":0.5365099906921387},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.47222447395324707},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.4633519947528839},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37425899505615234},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.36673903465270996},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3310418128967285},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.305046945810318},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11797618865966797},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000907","descriptor_name":"Antibodies, Bacterial","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D001770","descriptor_name":"Blood Bactericidal Activity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003550","descriptor_name":"Cystic Fibrosis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003550","descriptor_name":"Cystic Fibrosis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011550","descriptor_name":"Pseudomonas aeruginosa","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011552","descriptor_name":"Pseudomonas Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D011552","descriptor_name":"Pseudomonas Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1111/j.1699-0463.1977.tb03619.x","doi":"https://doi.org/10.1111/j.1699-0463.1977.tb03619.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1699-0463.1977.tb03619.x","pdf_url":null,"source":{"id":"https://openalex.org/S4210228615","display_name":"Acta Pathologica Microbiologica Scandinavica Section C Immunology","issn_l":"0108-0202","issn":["0108-0202","0304-1328"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Pathologica Microbiologica Scandinavica Section C Immunology","raw_type":"journal-article"},{"id":"pmid:404841","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/404841","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","raw_type":"Comparative Study"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/29a39520-20ec-11dd-bc23-000ea68e967b","doi":null,"is_oa":false,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/29a39520-20ec-11dd-bc23-000ea68e967b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"H\u00f8iby , N 2007 , ' Pseudomonas aeruginosa infection in cystic fibrosis ' , APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum , vol. 115 , no. 5 , pp. 621-628 .","raw_type":"article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W45096837","https://openalex.org/W120298392","https://openalex.org/W202063378","https://openalex.org/W1517293159","https://openalex.org/W1593976367","https://openalex.org/W1908120737","https://openalex.org/W1955875058","https://openalex.org/W1979043857","https://openalex.org/W1984163525","https://openalex.org/W1986679386","https://openalex.org/W1995472953","https://openalex.org/W2002259014","https://openalex.org/W2012323946","https://openalex.org/W2019290250","https://openalex.org/W2037058126","https://openalex.org/W2071996844","https://openalex.org/W2079452790","https://openalex.org/W2087221750","https://openalex.org/W2105876918","https://openalex.org/W2105987375","https://openalex.org/W2111028614","https://openalex.org/W2113230460","https://openalex.org/W2124209702","https://openalex.org/W2135526364","https://openalex.org/W2139880915","https://openalex.org/W2143032634","https://openalex.org/W2173161343","https://openalex.org/W2257556519","https://openalex.org/W2312443628","https://openalex.org/W2331462801","https://openalex.org/W2339371772","https://openalex.org/W2343180056","https://openalex.org/W2411867234","https://openalex.org/W2438140162","https://openalex.org/W2615771601","https://openalex.org/W2799153656","https://openalex.org/W3026325714","https://openalex.org/W4313311152","https://openalex.org/W4313389466","https://openalex.org/W4313429286"],"related_works":["https://openalex.org/W1837361346","https://openalex.org/W2003586252","https://openalex.org/W2057394782","https://openalex.org/W2127847928","https://openalex.org/W1602247801","https://openalex.org/W2152206129","https://openalex.org/W2135120982","https://openalex.org/W1903134188","https://openalex.org/W3197359560","https://openalex.org/W2160851127"],"abstract_inverted_index":{"P.":[0,34,109,128,147,160,180],"aeruginosa":[1,35,110,129,181],"strains":[2,36,45,101],"originating":[3,80,102],"from":[4,38,46,81,100,103,153],"the":[5,28,50,64,177,185],"respiratory":[6],"tract":[7],"of":[8,31,53,127,187],"patients":[9,15,40,48,85,107,156],"with":[10,16,22,86,95,113,139,159,163],"cystic":[11],"fibrosis":[12],"(CF)":[13],"and":[14,71,141,162],"other":[17],"diseases":[18],"(non-CF)":[19],"were":[20,41,74],"analysed":[21],"regard":[23],"to":[24,27,49,66,77,97],"their":[25],"sensitivity":[26,65,99],"bactericidal":[29,51,58,122,174],"activity":[30,52,59,123,175],"human":[32,55,68],"serum.":[33,56],"isolated":[37],"CF":[39,84,106,116,137,142,155],"more":[42],"sensitive":[43],"than":[44],"non-CF":[47],"normal":[54,67,114],"The":[57],"was":[60,149],"heatlabile.":[61],"As":[62],"regards":[63],"serum,":[69],"mucoid":[70],"non-mucoid":[72],"variants":[73],"not":[75,93,150],"found":[76],"differ.":[78],"Strains":[79],"chronically":[82,157],"infected":[83,158],"many":[87,164],"precipitins":[88,140,145,165],"against":[89,124,146,166,176],"these":[90,167],"bacteria":[91],"did":[92],"differ":[94],"respect":[96],"serum":[98],"intermittently":[104],"colonized":[105],"without":[108,144],"precipitins.":[111],"Compared":[112],"sera,":[115],"sera":[117,138,143],"showed":[118,169],"similar":[119],"or":[120],"higher":[121],"a":[125,170],"panel":[126],"strains.":[130],"In":[131],"this":[132],"respect,":[133],"any":[134],"difference":[135],"between":[136],"aeurginosa":[148],"found.":[151],"Sera":[152],"three":[154],"aeruginosa,":[161],"bacteria,":[168],"selective":[171],"inability":[172],"in":[173],"patients'":[178],"own":[179],"isolate":[182],"possibly":[183],"reflecting":[184],"presence":[186],"\"bactericidal":[188],"blocking\"":[189],"antibodies.":[190]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}