{"id":"https://openalex.org/W2044600697","doi":"https://doi.org/10.1016/j.neubiorev.2003.11.001","title":"Sensitization of midbrain dopamine neuron reactivity and the self-administration of psychomotor stimulant drugs","display_name":"Sensitization of midbrain dopamine neuron reactivity and the self-administration of psychomotor stimulant drugs","publication_year":2003,"publication_date":"2003-12-16","ids":{"openalex":"https://openalex.org/W2044600697","doi":"https://doi.org/10.1016/j.neubiorev.2003.11.001","mag":"2044600697","pmid":"https://pubmed.ncbi.nlm.nih.gov/15019432"},"language":"en","primary_location":{"id":"doi:10.1016/j.neubiorev.2003.11.001","doi":"https://doi.org/10.1016/j.neubiorev.2003.11.001","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neubiorev.2003.11.001","pdf_url":null,"source":{"id":"https://openalex.org/S170052170","display_name":"Neuroscience & Biobehavioral Reviews","issn_l":"0149-7634","issn":["0149-7634","1873-7528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience & Biobehavioral Reviews","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045976914","display_name":"Paul Vezina","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Paul Vezina","raw_affiliation_strings":["Department of Psychiatry, The University of Chicago, 5841 S Maryland Avenue, MC 3077, Chicago, IL 60637-1478, USA. pvezina@yoda.bsd.uchicago.edu","Department of Psychiatry, The University of Chicago, 5841 S. Maryland Avenue, MC 3077, Chicago, IL 60637-1478, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, The University of Chicago, 5841 S Maryland Avenue, MC 3077, Chicago, IL 60637-1478, USA. pvezina@yoda.bsd.uchicago.edu","institution_ids":["https://openalex.org/I40347166"]},{"raw_affiliation_string":"Department of Psychiatry, The University of Chicago, 5841 S. Maryland Avenue, MC 3077, Chicago, IL 60637-1478, USA","institution_ids":["https://openalex.org/I40347166"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5045976914"],"corresponding_institution_ids":["https://openalex.org/I40347166"],"apc_list":{"value":4860,"currency":"USD","value_usd":4860},"apc_paid":null,"fwci":2.3654,"has_fulltext":false,"cited_by_count":513,"citation_normalized_percentile":{"value":0.89596879,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"27","issue":"8","first_page":"827","last_page":"839"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10042","display_name":"Neural and Behavioral Psychology Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/midbrain-dopaminergic-neurons","display_name":"midbrain dopaminergic neurons","score":0.8610000014305115},{"id":"https://openalex.org/keywords/amphetamine","display_name":"amphetamine","score":0.9879999756813049},{"id":"https://openalex.org/keywords/ventral-tegmental-area","display_name":"ventral tegmental area","score":0.9070000052452087},{"id":"https://openalex.org/keywords/drug-seeking-behavior","display_name":"drug-seeking behavior","score":0.5889999866485596},{"id":"https://openalex.org/keywords/reinstatement-of-drug-seeking","display_name":"reinstatement of drug seeking","score":0.9010000228881836},{"id":"https://openalex.org/keywords/locomotor-activity","display_name":"locomotor activity","score":0.8199999928474426},{"id":"https://openalex.org/keywords/drug-addiction","display_name":"drug addiction","score":0.6119999885559082},{"id":"https://openalex.org/keywords/substance-abuse-prevention","display_name":"substance use prevention","score":0.47200000286102295}],"concepts":[{"id":"https://openalex.org/C2776217527","wikidata":"https://www.wikidata.org/wiki/Q944828","display_name":"Sensitization","level":2,"score":0.7492169737815857},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.7385414838790894},{"id":"https://openalex.org/C2776552330","wikidata":"https://www.wikidata.org/wiki/Q1476178","display_name":"Nucleus accumbens","level":3,"score":0.7279962301254272},{"id":"https://openalex.org/C2780948874","wikidata":"https://www.wikidata.org/wiki/Q640562","display_name":"Ventral tegmental area","level":4,"score":0.7125096321105957},{"id":"https://openalex.org/C2777193897","wikidata":"https://www.wikidata.org/wiki/Q179452","display_name":"Amphetamine","level":3,"score":0.7074731588363647},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6396927237510681},{"id":"https://openalex.org/C2780557958","wikidata":"https://www.wikidata.org/wiki/Q211036","display_name":"Stimulant","level":2,"score":0.5748439431190491},{"id":"https://openalex.org/C552161191","wikidata":"https://www.wikidata.org/wiki/Q185080","display_name":"Midbrain","level":3,"score":0.5660737752914429},{"id":"https://openalex.org/C2778555786","wikidata":"https://www.wikidata.org/wiki/Q7448011","display_name":"Self-administration","level":2,"score":0.5649933815002441},{"id":"https://openalex.org/C137183658","wikidata":"https://www.wikidata.org/wiki/Q461076","display_name":"Dopaminergic","level":3,"score":0.507035493850708},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4849984347820282},{"id":"https://openalex.org/C48856860","wikidata":"https://www.wikidata.org/wiki/Q12029","display_name":"Addiction","level":2,"score":0.4609855115413666},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4429433345794678},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.36611443758010864},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.17901572585105896}],"mesh":[{"descriptor_ui":"D000661","descriptor_name":"Amphetamine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000661","descriptor_name":"Amphetamine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000697","descriptor_name":"Central Nervous System Stimulants","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000697","descriptor_name":"Central Nervous System Stimulants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001522","descriptor_name":"Behavior, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004298","descriptor_name":"Dopamine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008124","descriptor_name":"Locomotion","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008636","descriptor_name":"Mesencephalon","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D008636","descriptor_name":"Mesencephalon","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012646","descriptor_name":"Self Administration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.neubiorev.2003.11.001","doi":"https://doi.org/10.1016/j.neubiorev.2003.11.001","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neubiorev.2003.11.001","pdf_url":null,"source":{"id":"https://openalex.org/S170052170","display_name":"Neuroscience & Biobehavioral Reviews","issn_l":"0149-7634","issn":["0149-7634","1873-7528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience & Biobehavioral Reviews","raw_type":"journal-article"},{"id":"pmid:15019432","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15019432","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience and biobehavioral reviews","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1214100839","display_name":"Sensitization and Stimulant Self-Administration","funder_award_id":"R01DA009397","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G2837579948","display_name":null,"funder_award_id":"DA-9860","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G3886767180","display_name":null,"funder_award_id":"DA-9397","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G7491871510","display_name":"DOPAMINE NEUROTRANSMISSION AND AMPHETAMINE SENSITIZATION","funder_award_id":"R01DA009860","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"}],"funders":[{"id":"https://openalex.org/F4320332505","display_name":"U.S. Public Health Service","ror":"https://ror.org/05xf94514"},{"id":"https://openalex.org/F4320337347","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":120,"referenced_works":["https://openalex.org/W569893145","https://openalex.org/W637205171","https://openalex.org/W831631257","https://openalex.org/W1524081744","https://openalex.org/W1556555813","https://openalex.org/W1571808750","https://openalex.org/W1574751342","https://openalex.org/W1598659526","https://openalex.org/W1613719983","https://openalex.org/W1644438397","https://openalex.org/W1743432501","https://openalex.org/W1873552451","https://openalex.org/W1889428062","https://openalex.org/W1902584234","https://openalex.org/W1906260178","https://openalex.org/W1943803076","https://openalex.org/W1944101324","https://openalex.org/W1954660866","https://openalex.org/W1958729097","https://openalex.org/W1964056580","https://openalex.org/W1966879038","https://openalex.org/W1967313016","https://openalex.org/W1968707626","https://openalex.org/W1968889342","https://openalex.org/W1969793357","https://openalex.org/W1969969246","https://openalex.org/W1977353048","https://openalex.org/W1977404224","https://openalex.org/W1982202989","https://openalex.org/W1982641194","https://openalex.org/W1983138582","https://openalex.org/W1983869923","https://openalex.org/W1984777669","https://openalex.org/W1987258086","https://openalex.org/W1990377586","https://openalex.org/W1992351948","https://openalex.org/W1995701251","https://openalex.org/W1998420008","https://openalex.org/W1999660121","https://openalex.org/W1999830007","https://openalex.org/W2001056665","https://openalex.org/W2002495923","https://openalex.org/W2002720955","https://openalex.org/W2005644211","https://openalex.org/W2006120547","https://openalex.org/W2007756992","https://openalex.org/W2009243814","https://openalex.org/W2010569958","https://openalex.org/W2012972759","https://openalex.org/W2017277436","https://openalex.org/W2018514933","https://openalex.org/W2018651989","https://openalex.org/W2022406556","https://openalex.org/W2027145792","https://openalex.org/W2030288942","https://openalex.org/W2030957166","https://openalex.org/W2031101928","https://openalex.org/W2031849606","https://openalex.org/W2032436575","https://openalex.org/W2035487171","https://openalex.org/W2035611467","https://openalex.org/W2038733942","https://openalex.org/W2041028874","https://openalex.org/W2041870401","https://openalex.org/W2042200894","https://openalex.org/W2051077097","https://openalex.org/W2053615228","https://openalex.org/W2054046728","https://openalex.org/W2056815214","https://openalex.org/W2057670853","https://openalex.org/W2059691450","https://openalex.org/W2061344417","https://openalex.org/W2062444999","https://openalex.org/W2066144671","https://openalex.org/W2069472087","https://openalex.org/W2071671029","https://openalex.org/W2075625204","https://openalex.org/W2078827060","https://openalex.org/W2080774795","https://openalex.org/W2080834428","https://openalex.org/W2084954062","https://openalex.org/W2087685262","https://openalex.org/W2087730665","https://openalex.org/W2088342844","https://openalex.org/W2089292912","https://openalex.org/W2089891482","https://openalex.org/W2091951560","https://openalex.org/W2093716510","https://openalex.org/W2103057436","https://openalex.org/W2106862702","https://openalex.org/W2107854911","https://openalex.org/W2108917606","https://openalex.org/W2112824246","https://openalex.org/W2112919328","https://openalex.org/W2115600363","https://openalex.org/W2122592499","https://openalex.org/W2137123069","https://openalex.org/W2138563618","https://openalex.org/W2138856840","https://openalex.org/W2147773916","https://openalex.org/W2150459344","https://openalex.org/W2155815310","https://openalex.org/W2160531011","https://openalex.org/W2163324649","https://openalex.org/W2169193164","https://openalex.org/W2171539950","https://openalex.org/W2171592578","https://openalex.org/W2175469462","https://openalex.org/W2175913266","https://openalex.org/W2217170767","https://openalex.org/W2253791809","https://openalex.org/W2256818278","https://openalex.org/W2264979256","https://openalex.org/W2265262946","https://openalex.org/W2275219801","https://openalex.org/W4238226939","https://openalex.org/W4250168860","https://openalex.org/W6688457604","https://openalex.org/W6692501084","https://openalex.org/W6873878561"],"related_works":["https://openalex.org/W1556555813","https://openalex.org/W7097386609","https://openalex.org/W2009429333","https://openalex.org/W4313058224","https://openalex.org/W2126624662","https://openalex.org/W2041739013","https://openalex.org/W2151866018","https://openalex.org/W1971674365","https://openalex.org/W2899735294","https://openalex.org/W1958729097"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":15},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":15},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":19},{"year":2017,"cited_by_count":24},{"year":2016,"cited_by_count":23},{"year":2015,"cited_by_count":24},{"year":2014,"cited_by_count":35},{"year":2013,"cited_by_count":28},{"year":2012,"cited_by_count":25}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}