{"id":"https://openalex.org/W2044182115","doi":"https://doi.org/10.1590/s0004-27302013000800009","title":"Aldosterone secretion in patients with septic shock: a prospective study","display_name":"Aldosterone secretion in patients with septic shock: a prospective study","publication_year":2013,"publication_date":"2013-11-01","ids":{"openalex":"https://openalex.org/W2044182115","doi":"https://doi.org/10.1590/s0004-27302013000800009","mag":"2044182115","pmid":"https://pubmed.ncbi.nlm.nih.gov/24343633"},"language":"en","primary_location":{"id":"doi:10.1590/s0004-27302013000800009","doi":"https://doi.org/10.1590/s0004-27302013000800009","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s0004-27302013000800009","pdf_url":"https://www.scielo.br/j/abem/a/PKwL7ssvRBX7JZrFsdsGNdP/?lang=en&format=pdf","source":{"id":"https://openalex.org/S15262226","display_name":"Arquivos Brasileiros de Endocrinologia & Metabologia","issn_l":"0004-2730","issn":["0004-2730","1677-9487"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1"],"host_organization":"https://openalex.org/P4310319680","host_organization_name":"Editora da Universidade de S\u00e3o Paulo","host_organization_lineage":["https://openalex.org/P4310319680"],"host_organization_lineage_names":["Editora da Universidade de S\u00e3o Paulo"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arquivos Brasileiros de Endocrinologia & Metabologia","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.scielo.br/j/abem/a/PKwL7ssvRBX7JZrFsdsGNdP/?lang=en&format=pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012237745","display_name":"Rafael Barberena Moraes","orcid":"https://orcid.org/0000-0001-6631-7260","observed_orcids":["https://orcid.org/0000-0001-6631-7260"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]},{"id":"https://openalex.org/I4210097146","display_name":"Hospital de Cl\u00ednicas de Porto Alegre","ror":"https://ror.org/010we4y38","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210097146"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Rafael Barberena Moraes","raw_affiliation_strings":["Universidade Federal do Rio Grande do Sul,  Brazil","Porto Alegre, Rio Grande do Sul, Universidade Federal do Rio Grande do Sul, Hospital de Clinicas de Porto Alegre, Department of Internal Medicine, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal do Rio Grande do Sul,  Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Porto Alegre, Rio Grande do Sul, Universidade Federal do Rio Grande do Sul, Hospital de Clinicas de Porto Alegre, Department of Internal Medicine, Brazil","institution_ids":["https://openalex.org/I130442723","https://openalex.org/I4210097146"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023900869","display_name":"Gilberto Friedman","orcid":"https://orcid.org/0000-0001-9369-2488","observed_orcids":["https://orcid.org/0000-0001-9369-2488"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]},{"id":"https://openalex.org/I4210097146","display_name":"Hospital de Cl\u00ednicas de Porto Alegre","ror":"https://ror.org/010we4y38","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210097146"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Gilberto Friedman","raw_affiliation_strings":["Universidade Federal do Rio Grande do Sul,  Brazil","Porto Alegre, Rio Grande do Sul, Universidade Federal do Rio Grande do Sul, Hospital de Clinicas de Porto Alegre, Department of Internal Medicine, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal do Rio Grande do Sul,  Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Porto Alegre, Rio Grande do Sul, Universidade Federal do Rio Grande do Sul, Hospital de Clinicas de Porto Alegre, Department of Internal Medicine, Brazil","institution_ids":["https://openalex.org/I130442723","https://openalex.org/I4210097146"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035556085","display_name":"Marina Ver\u00e7oza Viana","orcid":"https://orcid.org/0000-0001-9564-4885","observed_orcids":["https://orcid.org/0000-0001-9564-4885"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]},{"id":"https://openalex.org/I4210097146","display_name":"Hospital de Cl\u00ednicas de Porto Alegre","ror":"https://ror.org/010we4y38","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210097146"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Marina Ver\u00e7oza Viana","raw_affiliation_strings":["Universidade Federal do Rio Grande do Sul,  Brazil","Porto Alegre, Rio Grande do Sul, Universidade Federal do Rio Grande do Sul, Hospital de Clinicas de Porto Alegre, Department of Internal Medicine, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal do Rio Grande do Sul,  Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Porto Alegre, Rio Grande do Sul, Universidade Federal do Rio Grande do Sul, Hospital de Clinicas de Porto Alegre, Department of Internal Medicine, Brazil","institution_ids":["https://openalex.org/I130442723","https://openalex.org/I4210097146"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006041620","display_name":"Tiago Ant\u00f4nio Tonietto","orcid":"https://orcid.org/0000-0002-5673-4017","observed_orcids":["https://orcid.org/0000-0002-5673-4017"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]},{"id":"https://openalex.org/I4210097146","display_name":"Hospital de Cl\u00ednicas de Porto Alegre","ror":"https://ror.org/010we4y38","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210097146"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Tiago Tonietto","raw_affiliation_strings":["Universidade Federal do Rio Grande do Sul,  Brazil","Porto Alegre, Rio Grande do Sul, Universidade Federal do Rio Grande do Sul, Hospital de Clinicas de Porto Alegre, Department of Internal Medicine, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal do Rio Grande do Sul,  Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Porto Alegre, Rio Grande do Sul, Universidade Federal do Rio Grande do Sul, Hospital de Clinicas de Porto Alegre, Department of Internal Medicine, Brazil","institution_ids":["https://openalex.org/I130442723","https://openalex.org/I4210097146"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067939841","display_name":"Henrique Saltz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117002","display_name":"Hospital Nossa Senhora da Concei\u00e7\u00e3o","ror":"https://ror.org/02smsax08","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210117002"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Henrique Saltz","raw_affiliation_strings":["Hospital Nossa Senhora da Concei\u00e7\u00e3o,  Brazil","Porto Alegre, RS, Hospital Nossa Senhora da Conceicao, Division of Critical Care Medicine, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Nossa Senhora da Concei\u00e7\u00e3o,  Brazil","institution_ids":["https://openalex.org/I4210117002"]},{"raw_affiliation_string":"Porto Alegre, RS, Hospital Nossa Senhora da Conceicao, Division of Critical Care Medicine, Brazil","institution_ids":["https://openalex.org/I4210117002"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074364100","display_name":"Mauro Ant\u00f4nio Czepielewski","orcid":"https://orcid.org/0000-0001-5083-5776","observed_orcids":["https://orcid.org/0000-0001-5083-5776"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]},{"id":"https://openalex.org/I4210097146","display_name":"Hospital de Cl\u00ednicas de Porto Alegre","ror":"https://ror.org/010we4y38","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210097146"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Mauro Ant\u00f4nio Czepielewski","raw_affiliation_strings":["UFRGS,  Brazil","Porto Alegre, Rio Grande do Sul, Universidade Federal do Rio Grande do Sul, HCPA, Department of Internal Medicine, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UFRGS,  Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Porto Alegre, Rio Grande do Sul, Universidade Federal do Rio Grande do Sul, HCPA, Department of Internal Medicine, Brazil","institution_ids":["https://openalex.org/I130442723","https://openalex.org/I4210097146"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6104,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.69101138,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"57","issue":"8","first_page":"636","last_page":"641"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":0.7519999742507935,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":0.7519999742507935,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11839","display_name":"Hormonal Regulation and Hypertension","score":0.19359999895095825,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.037700001150369644,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/septic-shock","display_name":"septic shock","score":0.8859999775886536},{"id":"https://openalex.org/keywords/aldosterone-secretion","display_name":"aldosterone secretion","score":0.9769999980926514},{"id":"https://openalex.org/keywords/zona-glomerulosa","display_name":"zona glomerulosa","score":0.7990000247955322},{"id":"https://openalex.org/keywords/renin-angiotensin-aldosterone-system","display_name":"renin-angiotensin-aldosterone system","score":0.9190000295639038},{"id":"https://openalex.org/keywords/acth-stimulation-test","display_name":"ACTH stimulation test","score":0.8859999775886536},{"id":"https://openalex.org/keywords/cortisol-secretion","display_name":"cortisol secretion","score":0.8960000276565552},{"id":"https://openalex.org/keywords/hypothalamic-pituitary-adrenal-axis","display_name":"hypothalamic-pituitary-adrenal axis","score":0.9890000224113464},{"id":"https://openalex.org/keywords/adrenal-dysfunction","display_name":"adrenal dysfunction","score":0.5590000152587891},{"id":"https://openalex.org/keywords/critically-ill-patients","display_name":"critically ill patients","score":0.753000020980835},{"id":"https://openalex.org/keywords/renin","display_name":"renin","score":0.7940000295639038}],"concepts":[{"id":"https://openalex.org/C2778525890","wikidata":"https://www.wikidata.org/wiki/Q184564","display_name":"Aldosterone","level":2,"score":0.9276409149169922},{"id":"https://openalex.org/C2780178468","wikidata":"https://www.wikidata.org/wiki/Q3551060","display_name":"Zona glomerulosa","level":4,"score":0.8634315729141235},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7644026279449463},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7374169230461121},{"id":"https://openalex.org/C2780546910","wikidata":"https://www.wikidata.org/wiki/Q185690","display_name":"Adrenocorticotropic hormone","level":3,"score":0.6292127370834351},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6002569794654846},{"id":"https://openalex.org/C138976137","wikidata":"https://www.wikidata.org/wiki/Q7201790","display_name":"Plasma renin activity","level":4,"score":0.570617139339447},{"id":"https://openalex.org/C198710026","wikidata":"https://www.wikidata.org/wiki/Q898218","display_name":"Renin\u2013angiotensin system","level":3,"score":0.5575373768806458},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.5052474141120911},{"id":"https://openalex.org/C2777628635","wikidata":"https://www.wikidata.org/wiki/Q1765564","display_name":"Septic shock","level":3,"score":0.4973140060901642},{"id":"https://openalex.org/C2780694816","wikidata":"https://www.wikidata.org/wiki/Q712294","display_name":"Adrenal gland","level":2,"score":0.42976847290992737},{"id":"https://openalex.org/C2778736161","wikidata":"https://www.wikidata.org/wiki/Q3301573","display_name":"Zona fasciculata","level":3,"score":0.426510751247406},{"id":"https://openalex.org/C2908929049","wikidata":"https://www.wikidata.org/wiki/Q65963433","display_name":"Angiotensin II","level":3,"score":0.4148094952106476},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.4137570261955261},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.3508782684803009},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.10996916890144348},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.0950569212436676}],"mesh":[{"descriptor_ui":"D000324","descriptor_name":"Adrenocorticotropic Hormone","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000450","descriptor_name":"Aldosterone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D003366","descriptor_name":"Cosyntropin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D003366","descriptor_name":"Cosyntropin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006854","descriptor_name":"Hydrocortisone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007030","descriptor_name":"Hypothalamo-Hypophyseal System","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010913","descriptor_name":"Pituitary-Adrenal System","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012083","descriptor_name":"Renin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D012084","descriptor_name":"Renin-Angiotensin System","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012772","descriptor_name":"Shock, Septic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012772","descriptor_name":"Shock, Septic","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D012772","descriptor_name":"Shock, Septic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D015383","descriptor_name":"Zona Fasciculata","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015384","descriptor_name":"Zona Glomerulosa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D053208","descriptor_name":"Kaplan-Meier Estimate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1590/s0004-27302013000800009","doi":"https://doi.org/10.1590/s0004-27302013000800009","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s0004-27302013000800009","pdf_url":"https://www.scielo.br/j/abem/a/PKwL7ssvRBX7JZrFsdsGNdP/?lang=en&format=pdf","source":{"id":"https://openalex.org/S15262226","display_name":"Arquivos Brasileiros de Endocrinologia & Metabologia","issn_l":"0004-2730","issn":["0004-2730","1677-9487"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1"],"host_organization":"https://openalex.org/P4310319680","host_organization_name":"Editora da Universidade de S\u00e3o Paulo","host_organization_lineage":["https://openalex.org/P4310319680"],"host_organization_lineage_names":["Editora da Universidade de S\u00e3o Paulo"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arquivos Brasileiros de Endocrinologia & Metabologia","raw_type":"journal-article"},{"id":"pmid:24343633","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24343633","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arquivos brasileiros de endocrinologia e metabologia","raw_type":"Journal Article"},{"id":"pmh:oai:americanae.aecid.es:2639107","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10183/195763","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:Reposit\u00f3rio Institucional da UFRGS","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:scielo:S0004-27302013000800009","doi":null,"is_oa":true,"landing_page_url":"http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302013000800009","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arquivos Brasileiros de Endocrinologia & Metabologia v.57 n.8 2013","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:www.lume.ufrgs.br:10183/195763","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10183/195763","pdf_url":"https://lume.ufrgs.br/bitstream/10183/195763/1/000908181.pdf","source":{"id":"https://openalex.org/S4306401468","display_name":"Lume (Universidade Federal do Rio Grande do Sul)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210097146","host_organization_name":"Hospital de Cl\u00ednicas de Porto Alegre","host_organization_lineage":["https://openalex.org/I4210097146"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Artigo de peri\u00f3dico"},{"id":"pmh:oai:americanae.aecid.es:2624669","doi":null,"is_oa":true,"landing_page_url":"http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302013000800009","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Arquivos Brasileiros de Endocrinologia & Metabologia v.57 n.8 2013","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:2185244237","doi":null,"is_oa":false,"landing_page_url":"https://scielo.br/pdf/abem/v57n8/09.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1590/s0004-27302013000800009","doi":"https://doi.org/10.1590/s0004-27302013000800009","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s0004-27302013000800009","pdf_url":"https://www.scielo.br/j/abem/a/PKwL7ssvRBX7JZrFsdsGNdP/?lang=en&format=pdf","source":{"id":"https://openalex.org/S15262226","display_name":"Arquivos Brasileiros de Endocrinologia & Metabologia","issn_l":"0004-2730","issn":["0004-2730","1677-9487"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1"],"host_organization":"https://openalex.org/P4310319680","host_organization_name":"Editora da Universidade de S\u00e3o Paulo","host_organization_lineage":["https://openalex.org/P4310319680"],"host_organization_lineage_names":["Editora da Universidade de S\u00e3o Paulo"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arquivos Brasileiros de Endocrinologia & Metabologia","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322177","display_name":"Hospital de Cl\u00ednicas de Porto Alegre","ror":"https://ror.org/010we4y38"},{"id":"https://openalex.org/F4320322987","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2044182115.pdf","grobid_xml":"https://content.openalex.org/works/W2044182115.grobid-xml"},"referenced_works_count":20,"referenced_works":["https://openalex.org/W1971097161","https://openalex.org/W1984592139","https://openalex.org/W1992311120","https://openalex.org/W2003814400","https://openalex.org/W2019043807","https://openalex.org/W2042268246","https://openalex.org/W2051431609","https://openalex.org/W2053980980","https://openalex.org/W2058337075","https://openalex.org/W2068111956","https://openalex.org/W2071637551","https://openalex.org/W2084829232","https://openalex.org/W2093440520","https://openalex.org/W2142927411","https://openalex.org/W2156618518","https://openalex.org/W2159281942","https://openalex.org/W2550507245","https://openalex.org/W2599527603","https://openalex.org/W2768146862","https://openalex.org/W4293242440"],"related_works":["https://openalex.org/W2185244237","https://openalex.org/W2331748422","https://openalex.org/W2624492894","https://openalex.org/W2625711482","https://openalex.org/W2003814400","https://openalex.org/W2073276747","https://openalex.org/W2095173447","https://openalex.org/W3033233138","https://openalex.org/W847078015","https://openalex.org/W2076107133"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"assess":[2],"serum":[3],"levels":[4,50],"of":[5,13,51,95,102,118,140],"the":[6,11,14,103,116,119,132,141],"main":[7],"factors":[8],"that":[9,138],"regulate":[10],"activation":[12,139],"zona":[15,104,107],"glomerulosa":[16,105],"and":[17,58,73,81,97,106],"aldosterone":[18,72,96],"production":[19],"in":[20,144],"patients":[21,45,91,147],"with":[22,46,70,87],"septic":[23,47],"shock,":[24,48],"as":[25,27],"well":[26],"their":[28],"response":[29],"to":[30,128],"a":[31,64],"high-dose":[32],"(250":[33],"\u00b5g)":[34],"adrenocorticotropic":[35],"hormone":[36],"(ACTH)":[37],"stimulation":[38],"test.":[39,66],"SUBJECTS":[40],"AND":[41],"METHODS:":[42],"In":[43],"27":[44],"baseline":[49,71],"aldosterone,":[52],"cortisol,":[53],"ACTH,":[54],"renin,":[55],"sodium,":[56],"potassium,":[57],"lactate":[59],"were":[60],"measured,":[61],"followed":[62],"by":[63,149],"cortrosyn":[65,77],"RESULTS:":[67],"Renin":[68],"correlated":[69],"its":[74,82],"variation":[75,83],"after":[76],"stimulation.":[78],"Baseline":[79],"cortisol":[80,98,123],"did":[84],"not":[85,126],"correlate":[86],"ACTH.":[88],"Only":[89],"three":[90],"had":[92],"concomitant":[93],"dysfunction":[94],"secretion.":[99],"CONCLUSIONS:":[100],"Activation":[101],"fasciculata":[108],"are":[109],"independent.":[110],"Aldosterone":[111],"secretion":[112,124],"is":[113],"dependent":[114],"on":[115,131],"integrity":[117],"renin-angiotensin-aldosterone":[120],"system,":[121],"whereas":[122],"does":[125],"appear":[127],"depend":[129],"predominantly":[130],"hypothalamic-pituitary-adrenal":[133],"axis.":[134],"These":[135],"results":[136],"suggest":[137],"adrenal":[142],"gland":[143],"critically":[145],"ill":[146],"occurs":[148],"multiple":[150],"mechanisms.":[151]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}