{"id":"https://openalex.org/W2043936612","doi":"https://doi.org/10.1111/j.1440-1843.2009.01700.x","title":"Asthma: Time to confront some inconvenient truths","display_name":"Asthma: Time to confront some inconvenient truths","publication_year":2010,"publication_date":"2010-01-26","ids":{"openalex":"https://openalex.org/W2043936612","doi":"https://doi.org/10.1111/j.1440-1843.2009.01700.x","mag":"2043936612","pmid":"https://pubmed.ncbi.nlm.nih.gov/20199640"},"language":"en","primary_location":{"id":"doi:10.1111/j.1440-1843.2009.01700.x","doi":"https://doi.org/10.1111/j.1440-1843.2009.01700.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1440-1843.2009.01700.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1440-1843.2009.01700.x","source":{"id":"https://openalex.org/S125119059","display_name":"Respirology","issn_l":"1323-7799","issn":["1323-7799","1440-1843"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respirology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1440-1843.2009.01700.x","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084726423","display_name":"Robert John Hancox","orcid":"https://orcid.org/0000-0002-3922-7144","observed_orcids":["https://orcid.org/0000-0002-3922-7144"]},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Robert J. HANCOX","raw_affiliation_strings":["Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand","Department of Preventive & Social Medicine, University of Otago, Dunedin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"Department of Preventive & Social Medicine, University of Otago, Dunedin","institution_ids":["https://openalex.org/I80281795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041041126","display_name":"Peter Neils Le Sou\u00ebf","orcid":"https://orcid.org/0000-0003-0930-1654","observed_orcids":["https://orcid.org/0000-0003-0930-1654"]},"institutions":[{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Peter N. LE SOU\u00cbF","raw_affiliation_strings":["School of Paediatrics and Child Health, University of Western Australia, Perth, Western Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Paediatrics and Child Health, University of Western Australia, Perth, Western Australia","institution_ids":["https://openalex.org/I177877127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008084743","display_name":"Gary P. Anderson","orcid":"https://orcid.org/0000-0001-6580-3398","observed_orcids":["https://orcid.org/0000-0001-6580-3398"]},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Gary P. ANDERSON","raw_affiliation_strings":["Departments of Medicine and Pharmacology, University of Melbourne, Melbourne, Victoria,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine and Pharmacology, University of Melbourne, Melbourne, Victoria,","institution_ids":["https://openalex.org/I165779595"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011926591","display_name":"Helen Kathryn Reddel","orcid":"https://orcid.org/0000-0002-6695-6350","observed_orcids":["https://orcid.org/0000-0002-6695-6350"]},"institutions":[{"id":"https://openalex.org/I2800858616","display_name":"Woolcock Institute of Medical Research","ror":"https://ror.org/04hy0x592","country_code":"AU","type":"facility","lineage":["https://openalex.org/I2799732068","https://openalex.org/I2800858616","https://openalex.org/I99043593"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Helen K. REDDEL","raw_affiliation_strings":["Woolcock Institute of Medical Research, Sydney, New South Wales,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Woolcock Institute of Medical Research, Sydney, New South Wales,","institution_ids":["https://openalex.org/I2800858616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040334922","display_name":"Anne Bernadette Chang","orcid":"https://orcid.org/0000-0002-1331-3706","observed_orcids":["https://orcid.org/0000-0002-1331-3706"]},"institutions":[{"id":"https://openalex.org/I29894533","display_name":"Charles Darwin University","ror":"https://ror.org/048zcaj52","country_code":"AU","type":"education","lineage":["https://openalex.org/I29894533"]},{"id":"https://openalex.org/I4210085939","display_name":"Menzies School of Health Research","ror":"https://ror.org/006mbby82","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I29894533","https://openalex.org/I4210085939"]},{"id":"https://openalex.org/I4210121854","display_name":"Queensland Children\u2019s Medical Research Institute","ror":"https://ror.org/02xa7j758","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210121854"]},{"id":"https://openalex.org/I4210167058","display_name":"Children's Health Queensland Hospital and Health Service","ror":"https://ror.org/02t3p7e85","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1302211766","https://openalex.org/I2801244131","https://openalex.org/I4210167058"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Anne B. CHANG","raw_affiliation_strings":["Child Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia","Respiratory Centre, Queensland Children's Medical Research Institute, Royal Children's Hospital, Brisbane, Queensland,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Child Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia","institution_ids":["https://openalex.org/I29894533","https://openalex.org/I4210085939"]},{"raw_affiliation_string":"Respiratory Centre, Queensland Children's Medical Research Institute, Royal Children's Hospital, Brisbane, Queensland,","institution_ids":["https://openalex.org/I4210121854","https://openalex.org/I4210167058"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059164140","display_name":"Richard W. Beasley","orcid":"https://orcid.org/0000-0003-0337-406X","observed_orcids":["https://orcid.org/0000-0003-0337-406X"]},"institutions":[{"id":"https://openalex.org/I4210136719","display_name":"Medical Research Institute of New Zealand","ror":"https://ror.org/047asq971","country_code":"NZ","type":"facility","lineage":["https://openalex.org/I4210136719"]}],"countries":["NZ"],"is_corresponding":true,"raw_author_name":"Richard BEASLEY","raw_affiliation_strings":["Medical Research Institute of New Zealand, Wellington, New Zealand,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Research Institute of New Zealand, Wellington, New Zealand,","institution_ids":["https://openalex.org/I4210136719"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5059164140"],"corresponding_institution_ids":["https://openalex.org/I4210136719"],"apc_list":{"value":4330,"currency":"USD","value_usd":4330},"apc_paid":null,"fwci":0.3539,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.33908388,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"15","issue":"2","first_page":"194","last_page":"201"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12664","display_name":"Clinical practice guidelines implementation","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12208","display_name":"Occupational exposure and asthma","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/asthma","display_name":"asthma","score":0.9589999914169312},{"id":"https://openalex.org/keywords/asthma-pathogenesis","display_name":"asthma pathogenesis","score":0.8759999871253967},{"id":"https://openalex.org/keywords/asthma-prevention","display_name":"asthma prevention","score":0.8740000128746033},{"id":"https://openalex.org/keywords/asthma-management","display_name":"asthma management","score":0.7870000004768372},{"id":"https://openalex.org/keywords/public-health-strategy","display_name":"public health strategy","score":0.6499999761581421},{"id":"https://openalex.org/keywords/primary-care","display_name":"primary care","score":0.7870000004768372},{"id":"https://openalex.org/keywords/clinical-guidelines","display_name":"clinical guidelines","score":0.6129999756813049},{"id":"https://openalex.org/keywords/translational-research","display_name":"translational research","score":0.878000020980835},{"id":"https://openalex.org/keywords/gene-environment-interaction","display_name":"gene-environment interaction","score":0.8659999966621399},{"id":"https://openalex.org/keywords/developing-countries","display_name":"developing countries","score":0.3109999895095825}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8295972347259521},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.8052541017532349},{"id":"https://openalex.org/C138816342","wikidata":"https://www.wikidata.org/wiki/Q189603","display_name":"Public health","level":2,"score":0.6049966216087341},{"id":"https://openalex.org/C3018080372","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma management","level":3,"score":0.6022219657897949},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5347859859466553},{"id":"https://openalex.org/C128544194","wikidata":"https://www.wikidata.org/wiki/Q474859","display_name":"Translational research","level":2,"score":0.420947790145874},{"id":"https://openalex.org/C39549134","wikidata":"https://www.wikidata.org/wiki/Q133080","display_name":"Public relations","level":1,"score":0.32773280143737793},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.2358212172985077},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.14785942435264587},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.08771213889122009},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D004358","descriptor_name":"Drug Therapy","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011320","descriptor_name":"Primary Health Care","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":false},{"descriptor_ui":"D011634","descriptor_name":"Public Health","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019983","descriptor_name":"Guideline Adherence","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1111/j.1440-1843.2009.01700.x","doi":"https://doi.org/10.1111/j.1440-1843.2009.01700.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1440-1843.2009.01700.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1440-1843.2009.01700.x","source":{"id":"https://openalex.org/S125119059","display_name":"Respirology","issn_l":"1323-7799","issn":["1323-7799","1440-1843"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respirology","raw_type":"journal-article"},{"id":"pmid:20199640","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20199640","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respirology (Carlton, Vic.)","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:publications/03f0da84-1414-41cc-be35-c4bfd1da490f","doi":null,"is_oa":false,"landing_page_url":"https://research-repository.uwa.edu.au/en/publications/03f0da84-1414-41cc-be35-c4bfd1da490f","pdf_url":null,"source":{"id":"https://openalex.org/S4306402523","display_name":"UWA Profiles and Research Repository (University of Western Australia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177877127","host_organization_name":"The University of Western Australia","host_organization_lineage":["https://openalex.org/I177877127"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Hancox, R J, Le Souef, P, Anderson, G P, Reddel, H K, Chang, A B & Beasley, R 2010, 'Asthma: Time to confront some inconvenient truths', Respirology, vol. 15, pp. 194-201. https://doi.org/10.1111/j.1440-1843.2009.01700.x","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1111/j.1440-1843.2009.01700.x","doi":"https://doi.org/10.1111/j.1440-1843.2009.01700.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1440-1843.2009.01700.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1440-1843.2009.01700.x","source":{"id":"https://openalex.org/S125119059","display_name":"Respirology","issn_l":"1323-7799","issn":["1323-7799","1440-1843"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respirology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2043936612.pdf","grobid_xml":"https://content.openalex.org/works/W2043936612.grobid-xml"},"referenced_works_count":94,"referenced_works":["https://openalex.org/W327551637","https://openalex.org/W1561164333","https://openalex.org/W1594567624","https://openalex.org/W1942126698","https://openalex.org/W1963759527","https://openalex.org/W1965397792","https://openalex.org/W1970969615","https://openalex.org/W1971346562","https://openalex.org/W1971722581","https://openalex.org/W1976282279","https://openalex.org/W1979866174","https://openalex.org/W1980160429","https://openalex.org/W1982352830","https://openalex.org/W1984797374","https://openalex.org/W1985028853","https://openalex.org/W1985459290","https://openalex.org/W1989369079","https://openalex.org/W1990168621","https://openalex.org/W1990374418","https://openalex.org/W1991968623","https://openalex.org/W1992513419","https://openalex.org/W1994307831","https://openalex.org/W1994364818","https://openalex.org/W1995584982","https://openalex.org/W1997061712","https://openalex.org/W1997120806","https://openalex.org/W2000213276","https://openalex.org/W2001316554","https://openalex.org/W2001627597","https://openalex.org/W2007794051","https://openalex.org/W2008945707","https://openalex.org/W2009200551","https://openalex.org/W2010998136","https://openalex.org/W2020722855","https://openalex.org/W2027999944","https://openalex.org/W2034538777","https://openalex.org/W2035797266","https://openalex.org/W2038028146","https://openalex.org/W2043435391","https://openalex.org/W2043990114","https://openalex.org/W2047265249","https://openalex.org/W2050107000","https://openalex.org/W2050958492","https://openalex.org/W2053351348","https://openalex.org/W2055432567","https://openalex.org/W2060492140","https://openalex.org/W2062417667","https://openalex.org/W2066987620","https://openalex.org/W2068591024","https://openalex.org/W2069834760","https://openalex.org/W2070218296","https://openalex.org/W2073342172","https://openalex.org/W2073802637","https://openalex.org/W2074134575","https://openalex.org/W2080888300","https://openalex.org/W2100247174","https://openalex.org/W2104004679","https://openalex.org/W2104078610","https://openalex.org/W2106715003","https://openalex.org/W2106852187","https://openalex.org/W2110536082","https://openalex.org/W2110727393","https://openalex.org/W2112718944","https://openalex.org/W2113624460","https://openalex.org/W2115150707","https://openalex.org/W2123026345","https://openalex.org/W2124481948","https://openalex.org/W2125158574","https://openalex.org/W2129569282","https://openalex.org/W2132216860","https://openalex.org/W2138027296","https://openalex.org/W2142679365","https://openalex.org/W2147489728","https://openalex.org/W2151165850","https://openalex.org/W2154761796","https://openalex.org/W2155774990","https://openalex.org/W2155830934","https://openalex.org/W2157110918","https://openalex.org/W2157278980","https://openalex.org/W2158308846","https://openalex.org/W2160621537","https://openalex.org/W2161450196","https://openalex.org/W2162317318","https://openalex.org/W2165010366","https://openalex.org/W2166918396","https://openalex.org/W2169433957","https://openalex.org/W2170623205","https://openalex.org/W2170637423","https://openalex.org/W2171644239","https://openalex.org/W2312397711","https://openalex.org/W2395012385","https://openalex.org/W2470519651","https://openalex.org/W4211122169","https://openalex.org/W4295816668"],"related_works":["https://openalex.org/W2132508536","https://openalex.org/W1967275971","https://openalex.org/W4288593418","https://openalex.org/W4284701328","https://openalex.org/W4308933051","https://openalex.org/W2040337101","https://openalex.org/W2035941189","https://openalex.org/W2165367047","https://openalex.org/W1613323871","https://openalex.org/W4402642016"],"abstract_inverted_index":{"Despite":[0],"major":[1],"advances":[2],"in":[3,13,106,139,167],"the":[4,7,15,45,96,107,140,155,160],"understanding":[5],"of":[6,9,47,77,109,124],"pathogenesis":[8],"asthma":[10,49,78,130,168],"and":[11,22,69,72,115,146,170],"improvements":[12,105],"management,":[14],"accompanying":[16],"benefits":[17],"from":[18],"public":[19,37,113],"health":[20,38,114],"initiatives":[21],"clinical":[23],"practice":[24],"have":[25],"arguably":[26],"been":[27],"less":[28],"than":[29],"expected.":[30],"For":[31],"example,":[32],"there":[33],"are":[34,150],"no":[35],"effective":[36],"strategies":[39],"or":[40,50],"treatment":[41],"regimes":[42],"that":[43,95,102,135,171],"reduce":[44],"risk":[46],"developing":[48,141],"influence":[51],"its":[52],"natural":[53],"history.":[54],"These":[55],"represent":[56,120],"priority":[57,97],"areas":[58],"for":[59,129],"future":[60],"translational":[61],"research,":[62],"which":[63,172],"would":[64],"need":[65],"to":[66,83,99,104,158],"investigate":[67],"genetic":[68],"environmental":[70],"interactions":[71],"vaccine":[73],"strategies.":[74],"In":[75],"terms":[76],"management":[79,169],"it":[80],"is":[81,98,164,173],"tempting":[82],"focus":[84],"on":[85],"novel":[86],"drug":[87],"therapies;":[88],"however,":[89],"a":[90],"case":[91],"can":[92,136],"be":[93,137],"made":[94],"undertake":[100],"research":[101],"leads":[103],"use":[108],"existing":[110],"treatments":[111],"through":[112],"primary":[116],"care":[117],"initiatives.":[118],"Guidelines":[119],"an":[121],"important":[122],"component":[123],"this":[125],"approach,":[126],"with":[127],"recommendations":[128],"imbedded":[131],"within":[132],"respiratory":[133,148],"guidelines":[134],"implemented":[138],"world":[142],"where":[143],"other":[144],"acute":[145],"chronic":[147],"disorders":[149],"common.":[151],"This":[152],"approach":[153],"offers":[154],"best":[156],"opportunity":[157],"close":[159],"gap":[161],"between":[162],"what":[163],"currently":[165],"achieved":[166],"potentially":[174],"achievable.":[175]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
