{"id":"https://openalex.org/W2043928225","doi":"https://doi.org/10.1080/10611860410001724468","title":"Peptide-mediated Gene Transfer of Cationic Lipid/Plasmid DNA Complexes to Endothelial Cells","display_name":"Peptide-mediated Gene Transfer of Cationic Lipid/Plasmid DNA Complexes to Endothelial Cells","publication_year":2004,"publication_date":"2004-05-01","ids":{"openalex":"https://openalex.org/W2043928225","doi":"https://doi.org/10.1080/10611860410001724468","mag":"2043928225","pmid":"https://pubmed.ncbi.nlm.nih.gov/15506170"},"language":"en","primary_location":{"id":"doi:10.1080/10611860410001724468","doi":"https://doi.org/10.1080/10611860410001724468","is_oa":false,"landing_page_url":"https://doi.org/10.1080/10611860410001724468","pdf_url":null,"source":{"id":"https://openalex.org/S100629371","display_name":"Journal of drug targeting","issn_l":"1026-7158","issn":["1026-7158","1029-2330","1061-186X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Drug Targeting","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071711245","display_name":"Khursheed Anwer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K. Anwer","raw_affiliation_strings":["Expression Genetics, Huntsville, AL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Expression Genetics, Huntsville, AL, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113995690","display_name":"G. Kao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G. Kao","raw_affiliation_strings":["Valentis, The Woodlands, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Valentis, The Woodlands, TX, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057896007","display_name":"Alain P. Rolland","orcid":"https://orcid.org/0000-0002-7995-0548","observed_orcids":["https://orcid.org/0000-0002-7995-0548"]},"institutions":[{"id":"https://openalex.org/I4210100637","display_name":"Vical (United States)","ror":"https://ror.org/00w230w05","country_code":"US","type":"company","lineage":["https://openalex.org/I4210100637"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Rolland","raw_affiliation_strings":["Vical, Inc., San Diego, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vical, Inc., San Diego, CA, USA","institution_ids":["https://openalex.org/I4210100637"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054674747","display_name":"Wouter H. P. Driessen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W.H.P. Driessen","raw_affiliation_strings":["Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, FL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, FL, USA","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101549891","display_name":"Se\u00e1n M. Sullivan","orcid":"https://orcid.org/0000-0002-7393-263X","observed_orcids":["https://orcid.org/0000-0002-7393-263X"]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"S.M. Sullivan","raw_affiliation_strings":["Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, FL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, FL, USA","institution_ids":["https://openalex.org/I33213144"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5101549891"],"corresponding_institution_ids":["https://openalex.org/I33213144"],"apc_list":null,"apc_paid":null,"fwci":0.8306,"has_fulltext":false,"cited_by_count":30,"citation_normalized_percentile":{"value":0.67943571,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"12","issue":"4","first_page":"215","last_page":"221"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rgd-peptide","display_name":"RGD peptide","score":0.8610000014305115},{"id":"https://openalex.org/keywords/cationic-liposomes","display_name":"cationic liposomes","score":0.7509999871253967},{"id":"https://openalex.org/keywords/lipoplexes","display_name":"lipoplexes","score":0.847000002861023},{"id":"https://openalex.org/keywords/endothelial-cells","display_name":"endothelial cells","score":0.8370000123977661},{"id":"https://openalex.org/keywords/tumor-endothelium","display_name":"tumor endothelium","score":0.7450000047683716},{"id":"https://openalex.org/keywords/plasmid-transfection","display_name":"plasmid transfection","score":0.734000027179718},{"id":"https://openalex.org/keywords/liposome-uptake","display_name":"liposome uptake","score":0.5360000133514404}],"concepts":[{"id":"https://openalex.org/C185154212","wikidata":"https://www.wikidata.org/wiki/Q410454","display_name":"Liposome","level":2,"score":0.8119534254074097},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6212970018386841},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5310483574867249},{"id":"https://openalex.org/C2777411675","wikidata":"https://www.wikidata.org/wiki/Q1232438","display_name":"Umbilical vein","level":3,"score":0.5169419646263123},{"id":"https://openalex.org/C54009773","wikidata":"https://www.wikidata.org/wiki/Q1429031","display_name":"Transfection","level":3,"score":0.5024311542510986},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.5016849040985107},{"id":"https://openalex.org/C155887181","wikidata":"https://www.wikidata.org/wiki/Q5053552","display_name":"Cationic liposome","level":4,"score":0.4941134750843048},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.4567417502403259},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.405748575925827},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.2615397572517395},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15470194816589355},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08347195386886597}],"mesh":[{"descriptor_ui":"D000644","descriptor_name":"Quaternary Ammonium Compounds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000644","descriptor_name":"Quaternary Ammonium Compounds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000644","descriptor_name":"Quaternary Ammonium Compounds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002412","descriptor_name":"Cations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002412","descriptor_name":"Cations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002412","descriptor_name":"Cations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004220","descriptor_name":"Disulfides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004220","descriptor_name":"Disulfides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004220","descriptor_name":"Disulfides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008081","descriptor_name":"Liposomes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008081","descriptor_name":"Liposomes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008081","descriptor_name":"Liposomes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008156","descriptor_name":"Luciferases","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D008156","descriptor_name":"Luciferases","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D008156","descriptor_name":"Luciferases","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D008156","descriptor_name":"Luciferases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008156","descriptor_name":"Luciferases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008156","descriptor_name":"Luciferases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009842","descriptor_name":"Oligopeptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009842","descriptor_name":"Oligopeptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009842","descriptor_name":"Oligopeptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009842","descriptor_name":"Oligopeptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D009842","descriptor_name":"Oligopeptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D009842","descriptor_name":"Oligopeptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010957","descriptor_name":"Plasmids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010957","descriptor_name":"Plasmids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010957","descriptor_name":"Plasmids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014162","descriptor_name":"Transfection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014162","descriptor_name":"Transfection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014162","descriptor_name":"Transfection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014471","descriptor_name":"Umbilical Veins","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D014471","descriptor_name":"Umbilical Veins","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D014471","descriptor_name":"Umbilical Veins","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D014471","descriptor_name":"Umbilical Veins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014471","descriptor_name":"Umbilical Veins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014471","descriptor_name":"Umbilical Veins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018014","descriptor_name":"Gene Transfer Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018014","descriptor_name":"Gene Transfer Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018014","descriptor_name":"Gene Transfer Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D039302","descriptor_name":"Integrin alphaVbeta3","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D039302","descriptor_name":"Integrin alphaVbeta3","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D039302","descriptor_name":"Integrin alphaVbeta3","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1080/10611860410001724468","doi":"https://doi.org/10.1080/10611860410001724468","is_oa":false,"landing_page_url":"https://doi.org/10.1080/10611860410001724468","pdf_url":null,"source":{"id":"https://openalex.org/S100629371","display_name":"Journal of drug targeting","issn_l":"1026-7158","issn":["1026-7158","1029-2330","1061-186X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Drug Targeting","raw_type":"journal-article"},{"id":"pmid:15506170","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15506170","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of drug targeting","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8356999754905701,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Clean water and sanitation","score":0.41999998688697815,"id":"https://metadata.un.org/sdg/6"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1505196125","https://openalex.org/W1544263934","https://openalex.org/W2001728487","https://openalex.org/W2001753204","https://openalex.org/W2029773366","https://openalex.org/W2049134806","https://openalex.org/W2050085273","https://openalex.org/W2075984084","https://openalex.org/W2078741579","https://openalex.org/W2111871633","https://openalex.org/W2128644325","https://openalex.org/W2130639648","https://openalex.org/W2146898483","https://openalex.org/W2158071204","https://openalex.org/W2322388814"],"related_works":["https://openalex.org/W2172016706","https://openalex.org/W7135741233","https://openalex.org/W2069004681","https://openalex.org/W4234275011","https://openalex.org/W2417711872","https://openalex.org/W1993926540","https://openalex.org/W1994234691","https://openalex.org/W2010455234","https://openalex.org/W2142041258","https://openalex.org/W2033086871"],"abstract_inverted_index":{"The":[0,58,90,170,188,210],"purpose":[1],"of":[2,30,42,74,122,143,225,236,262,272],"this":[3],"research":[4],"is":[5],"to":[6,17,25,35,98,133,166,182,242,256,284],"develop":[7],"ligand-targeted":[8],"plasmid":[9,195],"based":[10],"gene":[11,15,180,245,282],"delivery":[12],"systems":[13],"for":[14,77,146,161,179],"transfer":[16,181,246,283],"tumor":[18],"endothelium.":[19],"Cell":[20],"adhesion":[21],"assays":[22],"were":[23,46,96,176,190],"used":[24],"test":[26],"the":[27,86,144,148,162,167,219,234,237,260,266,273],"peptide":[28],"inhibition":[29],"human":[31,112,136],"endothelial":[32,115,139,285],"cell":[33,140],"adsorption":[34],"vitronectin-treated":[36],"tissue":[37],"culture":[38],"plates.":[39],"A":[40],"series":[41],"RGD":[43,240,276],"containing":[44],"peptides":[45,64,95],"tested":[47,118,178],"in":[48,127,205,251,259],"linear":[49,59],"form":[50],"and":[51,54,60,92,100,150,172,216],"with":[52,107,197,268],"one":[53],"two":[55,61,75],"disulfide":[56,62,82,94,152,164,174,239,275],"bonds.":[57],"bond":[63,83],"yielded":[65,79],"similar":[66],"IC50":[67,87],"(approximately":[68],"1":[69],"x":[70],"10(-7)":[71],"M).":[72],"Substitution":[73],"methionines":[76],"cysteines":[78],"a":[80,120,201,222,269],"single":[81,91,149,168,171,238,274],"that":[84,232,257],"increased":[85,135,244],"by":[88,111,156,192,214,247,264],"10-fold.":[89,248],"double":[93,151,163,173],"derivatized":[97],"N-succinyl-dioleoylphopsphatidylethanolamine":[99],"incorporated":[101],"into":[102],"100":[103],"nm":[104],"liposomes":[105,145,199],"radiolabeled":[106],"H-cholesterylhexadecylether.":[108],"Liposome":[109,154],"uptake":[110,142,155],"umbilical":[113,137],"vein":[114],"cells":[116],"was":[117,158,212],"as":[119],"function":[121],"lipopeptide":[123,241,263,280],"surface":[124,129],"density.":[125],"Increase":[126],"membrane":[128],"density":[130],"from":[131],"5":[132],"20mol%":[134,243],"derived":[138],"(HUVEC)":[141],"both":[147],"peptides.":[153],"HUVECs":[157,183,267],"3-fold":[159],"greater":[160],"compared":[165],"disulfide.":[169],"lipopeptides":[175],"then":[177],"using":[184],"DOTMA:Cholesterol":[185],"cationic":[186],"liposomes.":[187],"polyplexes":[189],"formed":[191],"rapidly":[193],"mixing":[194],"DNA":[196],"DOTMA:CHOL":[198],"at":[200],"3:1":[202],"charge":[203],"ratio":[204],"2%":[206],"ethanol,":[207],"10%":[208],"lactose.":[209],"ethanol":[211],"removed":[213],"lyophilization":[215],"upon":[217],"rehydration,":[218],"lipoplexes":[220],"had":[221],"mean":[223],"diameter":[224],"approximately":[226],"100nm.":[227],"HUVEC":[228],"transfection":[229,252],"studies":[230],"showed":[231],"increasing":[233],"mol%":[235],"This":[249],"increase":[250],"could":[253],"be":[254],"reduced":[255],"obtained":[258],"absence":[261],"co-incubating":[265],"100-fold":[270],"excess":[271],"peptide,":[277],"thus":[278],"demonstrating":[279],"mediated":[281],"cells.":[286]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}