{"id":"https://openalex.org/W2043928194","doi":"https://doi.org/10.1073/pnas.1321092110","title":"PirB regulates a structural substrate for cortical plasticity","display_name":"PirB regulates a structural substrate for cortical plasticity","publication_year":2013,"publication_date":"2013-12-03","ids":{"openalex":"https://openalex.org/W2043928194","doi":"https://doi.org/10.1073/pnas.1321092110","mag":"2043928194","pmid":"https://pubmed.ncbi.nlm.nih.gov/24302763","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3870667"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.1321092110","doi":"https://doi.org/10.1073/pnas.1321092110","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.1321092110","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3870667","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065861787","display_name":"Maja R. Djurisic","orcid":"https://orcid.org/0000-0002-2794-9406","observed_orcids":["https://orcid.org/0000-0002-2794-9406"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maja Djurisic","raw_affiliation_strings":["Bio-X, James H. Clark Center, Stanford University, Stanford, CA 94305;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-X, James H. Clark Center, Stanford University, Stanford, CA 94305;","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034671848","display_name":"George S. Vidal","orcid":"https://orcid.org/0000-0002-8623-7476","observed_orcids":["https://orcid.org/0000-0002-8623-7476"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"George S. Vidal","raw_affiliation_strings":["Bio-X, James H. Clark Center, Stanford University, Stanford, CA 94305;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-X, James H. Clark Center, Stanford University, Stanford, CA 94305;","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035132189","display_name":"Miriam Mann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149899117","display_name":"Max Planck Society","ror":"https://ror.org/01hhn8329","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I149899117"]},{"id":"https://openalex.org/I4210139319","display_name":"Max Planck Institute of Neurobiology","ror":"https://ror.org/03ap2av50","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210139319","https://openalex.org/I4387153642"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Miriam Mann","raw_affiliation_strings":["Max Planck Institute of Neurobiology, D-82152 Martinsried, Germany; and","Department: Synapses-Circuits-Plasticity / Bonhoeffer, MPI of Neurobiology, Max Planck Society"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Max Planck Institute of Neurobiology, D-82152 Martinsried, Germany; and","institution_ids":["https://openalex.org/I4210139319"]},{"raw_affiliation_string":"Department: Synapses-Circuits-Plasticity / Bonhoeffer, MPI of Neurobiology, Max Planck Society","institution_ids":["https://openalex.org/I149899117","https://openalex.org/I4210139319"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080084422","display_name":"Adam Aharon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185103710","display_name":"University of California, Santa Cruz","ror":"https://ror.org/03s65by71","country_code":"US","type":"education","lineage":["https://openalex.org/I185103710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adam Aharon","raw_affiliation_strings":["Molecular, Cell and Developmental Biology, University of California, Santa Cruz, CA 95064"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular, Cell and Developmental Biology, University of California, Santa Cruz, CA 95064","institution_ids":["https://openalex.org/I185103710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100452177","display_name":"Taeho Kim","orcid":"https://orcid.org/0000-0002-1642-5746","observed_orcids":["https://orcid.org/0000-0002-1642-5746"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Taeho Kim","raw_affiliation_strings":["Bio-X, James H. Clark Center, Stanford University, Stanford, CA 94305;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-X, James H. Clark Center, Stanford University, Stanford, CA 94305;","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103503949","display_name":"Alexandre Ferr\u00e3o Santos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149899117","display_name":"Max Planck Society","ror":"https://ror.org/01hhn8329","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I149899117"]},{"id":"https://openalex.org/I4210139319","display_name":"Max Planck Institute of Neurobiology","ror":"https://ror.org/03ap2av50","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210139319","https://openalex.org/I4387153642"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Alexandre Ferrao Santos","raw_affiliation_strings":["Max Planck Institute of Neurobiology, D-82152 Martinsried, Germany; and","Department: Synapses-Circuits-Plasticity / Bonhoeffer, MPI of Neurobiology, Max Planck Society"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Max Planck Institute of Neurobiology, D-82152 Martinsried, Germany; and","institution_ids":["https://openalex.org/I4210139319"]},{"raw_affiliation_string":"Department: Synapses-Circuits-Plasticity / Bonhoeffer, MPI of Neurobiology, Max Planck Society","institution_ids":["https://openalex.org/I149899117","https://openalex.org/I4210139319"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043330161","display_name":"Yi Zuo","orcid":"https://orcid.org/0000-0001-9020-0003","observed_orcids":["https://orcid.org/0000-0001-9020-0003"]},"institutions":[{"id":"https://openalex.org/I185103710","display_name":"University of California, Santa Cruz","ror":"https://ror.org/03s65by71","country_code":"US","type":"education","lineage":["https://openalex.org/I185103710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yi Zuo","raw_affiliation_strings":["Molecular, Cell and Developmental Biology, University of California, Santa Cruz, CA 95064"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular, Cell and Developmental Biology, University of California, Santa Cruz, CA 95064","institution_ids":["https://openalex.org/I185103710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071487971","display_name":"Mark H\u00fcbener","orcid":"https://orcid.org/0000-0001-8367-9132","observed_orcids":["https://orcid.org/0000-0001-8367-9132"]},"institutions":[{"id":"https://openalex.org/I149899117","display_name":"Max Planck Society","ror":"https://ror.org/01hhn8329","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I149899117"]},{"id":"https://openalex.org/I4210139319","display_name":"Max Planck Institute of Neurobiology","ror":"https://ror.org/03ap2av50","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210139319","https://openalex.org/I4387153642"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Mark H\u00fcbener","raw_affiliation_strings":["Max Planck Institute of Neurobiology, D-82152 Martinsried, Germany; and","Department: Synapses-Circuits-Plasticity / Bonhoeffer, MPI of Neurobiology, Max Planck Society"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Max Planck Institute of Neurobiology, D-82152 Martinsried, Germany; and","institution_ids":["https://openalex.org/I4210139319"]},{"raw_affiliation_string":"Department: Synapses-Circuits-Plasticity / Bonhoeffer, MPI of Neurobiology, Max Planck Society","institution_ids":["https://openalex.org/I149899117","https://openalex.org/I4210139319"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030290673","display_name":"Carla J. Shatz","orcid":"https://orcid.org/0000-0001-5432-5917","observed_orcids":["https://orcid.org/0000-0001-5432-5917"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carla J. Shatz","raw_affiliation_strings":["Bio-X, James H. Clark Center, Stanford University, Stanford, CA 94305;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-X, James H. Clark Center, Stanford University, Stanford, CA 94305;","institution_ids":["https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.0843,"has_fulltext":false,"cited_by_count":79,"citation_normalized_percentile":{"value":0.94225885,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"110","issue":"51","first_page":"20771","last_page":"20776"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pirb","display_name":"PirB","score":0.9890000224113464},{"id":"https://openalex.org/keywords/ocular-dominance-plasticity","display_name":"ocular dominance plasticity","score":0.9549999833106995},{"id":"https://openalex.org/keywords/monocular-deprivation","display_name":"monocular deprivation","score":0.968999981880188},{"id":"https://openalex.org/keywords/dendritic-spine-density","display_name":"dendritic spine density","score":0.9520000219345093},{"id":"https://openalex.org/keywords/spine-stability","display_name":"spinal stability","score":0.6729999780654907},{"id":"https://openalex.org/keywords/long-term-potentiation","display_name":"long-term potentiation","score":0.7369999885559082},{"id":"https://openalex.org/keywords/long-term-depression","display_name":"long-term depression","score":0.9990000128746033},{"id":"https://openalex.org/keywords/miniature-synaptic-currents","display_name":"miniature synaptic currents","score":0.9300000071525574},{"id":"https://openalex.org/keywords/synaptic-plasticity","display_name":"synaptic plasticity","score":0.7200000286102295},{"id":"https://openalex.org/keywords/cortical-plasticity","display_name":"cortical plasticity","score":0.7570000290870667},{"id":"https://openalex.org/keywords/learning-and-memory","display_name":"learning and memory","score":0.7429999709129333}],"concepts":[{"id":"https://openalex.org/C111437709","wikidata":"https://www.wikidata.org/wiki/Q1277874","display_name":"Hebbian theory","level":3,"score":0.7542365789413452},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7377994060516357},{"id":"https://openalex.org/C98229152","wikidata":"https://www.wikidata.org/wiki/Q1551556","display_name":"Synaptic plasticity","level":3,"score":0.7022457718849182},{"id":"https://openalex.org/C47611674","wikidata":"https://www.wikidata.org/wiki/Q849491","display_name":"Neuroplasticity","level":2,"score":0.6542381048202515},{"id":"https://openalex.org/C79186407","wikidata":"https://www.wikidata.org/wiki/Q472074","display_name":"Plasticity","level":2,"score":0.6062621474266052},{"id":"https://openalex.org/C194973443","wikidata":"https://www.wikidata.org/wiki/Q1420291","display_name":"Metaplasticity","level":4,"score":0.5669843554496765},{"id":"https://openalex.org/C174884520","wikidata":"https://www.wikidata.org/wiki/Q902079","display_name":"Dendritic spine","level":3,"score":0.51959228515625},{"id":"https://openalex.org/C6929976","wikidata":"https://www.wikidata.org/wiki/Q3771881","display_name":"Regulator","level":3,"score":0.4463377594947815},{"id":"https://openalex.org/C2993191138","wikidata":"https://www.wikidata.org/wiki/Q849491","display_name":"Structural plasticity","level":2,"score":0.41272640228271484},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3634222745895386},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.28640228509902954},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.10025173425674438},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.06673592329025269},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.06553751230239868},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.0},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.0},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007858","descriptor_name":"Learning","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011971","descriptor_name":"Receptors, Immunologic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011971","descriptor_name":"Receptors, Immunologic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017774","descriptor_name":"Long-Term Potentiation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017966","descriptor_name":"Pyramidal Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D017966","descriptor_name":"Pyramidal Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019706","descriptor_name":"Excitatory Postsynaptic Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D023882","descriptor_name":"Dominance, Ocular","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1073/pnas.1321092110","doi":"https://doi.org/10.1073/pnas.1321092110","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.1321092110","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3030288","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3870667","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3870667","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3870667","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},{"id":"pmid:24302763","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24302763","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"Journal Article"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt4q96f0x0","doi":null,"is_oa":false,"landing_page_url":"https://escholarship.org/uc/item/4q96f0x0","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America, vol 110, iss 51","raw_type":"article"},{"id":"pmh:oai:escidoc.org:escidoc:1913989","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11858/00-001M-0000-0015-18CF-B","pdf_url":null,"source":{"id":"https://openalex.org/S7407052962","display_name":"Max Planck Digital Library","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210088280","host_organization_name":"Max Planck Digital Library","host_organization_lineage":["https://openalex.org/I4210088280"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.mpg.de:item_1913989","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11858/00-001M-0000-0015-18CF-B","pdf_url":null,"source":{"id":"https://openalex.org/S4306400654","display_name":"MPG.PuRe (Max Planck Society)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I149899117","host_organization_name":"Max Planck Society","host_organization_lineage":["https://openalex.org/I149899117"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:3030288","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3870667","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4554256649","display_name":null,"funder_award_id":"EY02858","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G5560910761","display_name":"Development of Visual Connections","funder_award_id":"R01EY002858","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G6100388859","display_name":"Enhancing synaptic and structural plasticity by manipulating PirB","funder_award_id":"F31EY023518","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G6300385797","display_name":"Development of synaptic abnormality in fragile X mice","funder_award_id":"R01MH094449","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G6505682216","display_name":null,"funder_award_id":"R01MH09449","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G963097883","display_name":"FETAL AND POSTNATAL DEVELOPMENT OF VISUAL CONNECTIONS","funder_award_id":"R37EY002858","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"}],"funders":[{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W1572640432","https://openalex.org/W1929487673","https://openalex.org/W1965552543","https://openalex.org/W1966155655","https://openalex.org/W1968661423","https://openalex.org/W1979019425","https://openalex.org/W1979755858","https://openalex.org/W1980073515","https://openalex.org/W1983553517","https://openalex.org/W1986246328","https://openalex.org/W2000097259","https://openalex.org/W2003502718","https://openalex.org/W2004268936","https://openalex.org/W2018843440","https://openalex.org/W2019523818","https://openalex.org/W2019601077","https://openalex.org/W2020634566","https://openalex.org/W2024880767","https://openalex.org/W2036970711","https://openalex.org/W2037969635","https://openalex.org/W2040145197","https://openalex.org/W2056431599","https://openalex.org/W2056748460","https://openalex.org/W2059288735","https://openalex.org/W2059337036","https://openalex.org/W2063781019","https://openalex.org/W2067415178","https://openalex.org/W2074623278","https://openalex.org/W2080089584","https://openalex.org/W2088446997","https://openalex.org/W2090043895","https://openalex.org/W2090319528","https://openalex.org/W2092356910","https://openalex.org/W2094455233","https://openalex.org/W2096021753","https://openalex.org/W2105312616","https://openalex.org/W2122427440","https://openalex.org/W2127810309","https://openalex.org/W2136830964","https://openalex.org/W2145255740","https://openalex.org/W2155256004","https://openalex.org/W2157055126","https://openalex.org/W2171223590"],"related_works":["https://openalex.org/W2526115813","https://openalex.org/W2248128968","https://openalex.org/W4212897917","https://openalex.org/W2003502718","https://openalex.org/W3194665693","https://openalex.org/W3126633407","https://openalex.org/W1743735834","https://openalex.org/W2796981943","https://openalex.org/W1915761180","https://openalex.org/W3197467040"],"abstract_inverted_index":{"Experience-driven":[0],"circuit":[1],"changes":[2],"underlie":[3],"learning":[4,131],"and":[5,18,58,74,102,121,125],"memory.":[6],"Monocular":[7],"deprivation":[8],"(MD)":[9],"engages":[10],"synaptic":[11,69],"mechanisms":[12],"of":[13,112],"ocular":[14],"dominance":[15],"(OD)":[16],"plasticity":[17,99],"generates":[19,80],"robust":[20],"increases":[21],"in":[22,84,87,89,106],"dendritic":[23],"spine":[24,42,56,85,114,120],"density":[25,57,86,124],"on":[26],"L5":[27],"pyramidal":[28],"neurons.":[29],"Here":[30],"we":[31],"show":[32],"that":[33],"the":[34,47,81,110,127],"paired":[35],"immunoglobulin-like":[36],"receptor":[37],"B":[38],"(PirB)":[39],"negatively":[40],"regulates":[41,119],"density,":[43],"as":[44,46],"well":[45],"threshold":[48,128],"for":[49,129],"adult":[50,96],"OD":[51,98],"plasticity.":[52],"In":[53,95],"PirB(-/-)":[54,90],"mice,":[55],"stability":[59],"are":[60],"significantly":[61],"greater":[62],"than":[63,105],"WT,":[64,88,107],"associated":[65],"with":[66,109],"higher-frequency":[67],"miniature":[68],"currents,":[70],"larger":[71,101],"long-term":[72,76],"potentiation,":[73],"deficient":[75],"depression.":[77],"Although":[78],"MD":[79],"expected":[82],"increase":[83,92],"this":[91],"is":[93,100],"occluded.":[94],"PirB(-/-),":[97],"more":[103],"rapid":[104],"consistent":[108],"maintenance":[111],"elevated":[113],"density.":[115],"Thus,":[116],"PirB":[117],"normally":[118],"excitatory":[122],"synapse":[123],"consequently":[126],"new":[130],"throughout":[132],"life.":[133]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}