{"id":"https://openalex.org/W2043917273","doi":"https://doi.org/10.1111/j.1399-3054.1997.tb03451.x","title":"Calcium ions as second messengers in guard cell signal transduction","display_name":"Calcium ions as second messengers in guard cell signal transduction","publication_year":1997,"publication_date":"1997-05-01","ids":{"openalex":"https://openalex.org/W2043917273","doi":"https://doi.org/10.1111/j.1399-3054.1997.tb03451.x","mag":"2043917273"},"language":"en","primary_location":{"id":"doi:10.1111/j.1399-3054.1997.tb03451.x","doi":"https://doi.org/10.1111/j.1399-3054.1997.tb03451.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1399-3054.1997.tb03451.x","pdf_url":null,"source":{"id":"https://openalex.org/S185046733","display_name":"Physiologia Plantarum","issn_l":"0031-9317","issn":["0031-9317","1399-3054"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiologia Plantarum","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066994019","display_name":"Martin Robert McAinsh","orcid":"https://orcid.org/0000-0003-4294-6470","observed_orcids":["https://orcid.org/0000-0003-4294-6470"]},"institutions":[{"id":"https://openalex.org/I67415387","display_name":"Lancaster University","ror":"https://ror.org/04f2nsd36","country_code":"GB","type":"education","lineage":["https://openalex.org/I67415387"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Martin R. McAinsh","raw_affiliation_strings":["Institute of Environmental and Biological Sciences, Division of Biological Sciences, Lancaster University, Lancaster LA1 4YQ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Environmental and Biological Sciences, Division of Biological Sciences, Lancaster University, Lancaster LA1 4YQ, UK","institution_ids":["https://openalex.org/I67415387"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061454476","display_name":"Colin Brownlee","orcid":"https://orcid.org/0000-0001-7838-230X","observed_orcids":["https://orcid.org/0000-0001-7838-230X"]},"institutions":[{"id":"https://openalex.org/I114472154","display_name":"Marine Biological Association of the United Kingdom","ror":"https://ror.org/0431sk359","country_code":"GB","type":"facility","lineage":["https://openalex.org/I114472154"]},{"id":"https://openalex.org/I2802566253","display_name":"Plymouth Marine Laboratory","ror":"https://ror.org/05av9mn02","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2802566253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Colin Brownlee","raw_affiliation_strings":["The Marine Biological Association, Plymouth Marine Laboratory, Citadel Hill, Plymouth PL1 2PB. UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Marine Biological Association, Plymouth Marine Laboratory, Citadel Hill, Plymouth PL1 2PB. UK","institution_ids":["https://openalex.org/I114472154","https://openalex.org/I2802566253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039142440","display_name":"Alistair M. Hetherington","orcid":"https://orcid.org/0000-0001-6060-9203","observed_orcids":["https://orcid.org/0000-0001-6060-9203"]},"institutions":[{"id":"https://openalex.org/I67415387","display_name":"Lancaster University","ror":"https://ror.org/04f2nsd36","country_code":"GB","type":"education","lineage":["https://openalex.org/I67415387"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alistair M. Hetherington","raw_affiliation_strings":["School of Biological Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological Sciences","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4150,"currency":"USD","value_usd":4150},"apc_paid":null,"fwci":24.5404,"has_fulltext":false,"cited_by_count":198,"citation_normalized_percentile":{"value":0.99670424,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"100","issue":"1","first_page":"16","last_page":"29"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10014","display_name":"Plant Stress Responses and Tolerance","score":0.8187999725341797,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10014","display_name":"Plant Stress Responses and Tolerance","score":0.8187999725341797,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12813","display_name":"Plant and Biological Electrophysiology Studies","score":0.10109999775886536,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.019600000232458115,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/calcium-signaling","display_name":"calcium signaling","score":0.8619999885559082},{"id":"https://openalex.org/keywords/second-messengers","display_name":"second messengers","score":0.7649999856948853},{"id":"https://openalex.org/keywords/stomatal-guard-cells","display_name":"stomatal guard cells","score":0.9070000052452087},{"id":"https://openalex.org/keywords/stomatal-aperture","display_name":"stomatal aperture","score":0.4970000088214874},{"id":"https://openalex.org/keywords/abscisic-acid","display_name":"abscisic acid","score":0.972000002861023},{"id":"https://openalex.org/keywords/stomatal-closure","display_name":"stomatal closure","score":0.8769999742507935},{"id":"https://openalex.org/keywords/signaling-specificity","display_name":"signaling specificity","score":0.5590000152587891},{"id":"https://openalex.org/keywords/plant-cell-signalling","display_name":"plant cell signalling","score":0.6970000267028809}],"concepts":[{"id":"https://openalex.org/C136547172","wikidata":"https://www.wikidata.org/wiki/Q241368","display_name":"Guard cell","level":2,"score":0.9929366111755371},{"id":"https://openalex.org/C87865070","wikidata":"https://www.wikidata.org/wiki/Q844863","display_name":"Turgor pressure","level":2,"score":0.8971214294433594},{"id":"https://openalex.org/C2779591172","wikidata":"https://www.wikidata.org/wiki/Q332211","display_name":"Abscisic acid","level":3,"score":0.7259587049484253},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.697262167930603},{"id":"https://openalex.org/C163235415","wikidata":"https://www.wikidata.org/wiki/Q899814","display_name":"Second messenger system","level":3,"score":0.6947128176689148},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6600822806358337},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5004539489746094},{"id":"https://openalex.org/C201571599","wikidata":"https://www.wikidata.org/wiki/Q5018840","display_name":"Calcium signaling","level":3,"score":0.49597224593162537},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.42670977115631104},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3255331516265869},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2990124225616455},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.06604695320129395}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1111/j.1399-3054.1997.tb03451.x","doi":"https://doi.org/10.1111/j.1399-3054.1997.tb03451.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1399-3054.1997.tb03451.x","pdf_url":null,"source":{"id":"https://openalex.org/S185046733","display_name":"Physiologia Plantarum","issn_l":"0031-9317","issn":["0031-9317","1399-3054"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiologia Plantarum","raw_type":"journal-article"},{"id":"doi:10.1034/j.1399-3054.1997.1000102.x","doi":"https://doi.org/10.1034/j.1399-3054.1997.1000102.x","is_oa":false,"landing_page_url":"https://doi.org/10.1034/j.1399-3054.1997.1000102.x","pdf_url":null,"source":{"id":"https://openalex.org/S185046733","display_name":"Physiologia Plantarum","issn_l":"0031-9317","issn":["0031-9317","1399-3054"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiologia Plantarum","raw_type":"journal-article"},{"id":"pmh:oai:eprints.lancs.ac.uk:26844","doi":null,"is_oa":false,"landing_page_url":"https://eprints.lancs.ac.uk/id/eprint/26844/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401916","display_name":"Lancaster EPrints (Lancaster University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67415387","host_organization_name":"Lancaster University","host_organization_lineage":["https://openalex.org/I67415387"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal Article"},{"id":"pmh:oai:research-information.bris.ac.uk:openaire_cris_publications/08e8eb99-6627-46e9-acdc-33b153be263a","doi":null,"is_oa":false,"landing_page_url":"https://research-information.bris.ac.uk/en/publications/08e8eb99-6627-46e9-acdc-33b153be263a","pdf_url":null,"source":{"id":"https://openalex.org/S7407055359","display_name":"Explore Bristol Research","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"McAinsh, M R, Brownlee, C & Hetherington, A M 1997, 'Calcium ions as second messengers in guard cell signal transduction', Physiologia Plantarum, vol. 100, no. 1, pp. 16-29.","raw_type":"info:eu-repo/semantics/review"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":121,"referenced_works":["https://openalex.org/W18293144","https://openalex.org/W28215203","https://openalex.org/W90003834","https://openalex.org/W94108745","https://openalex.org/W267467148","https://openalex.org/W391614615","https://openalex.org/W1515783001","https://openalex.org/W1526949879","https://openalex.org/W1546253761","https://openalex.org/W1552353464","https://openalex.org/W1557491684","https://openalex.org/W1565476905","https://openalex.org/W1583289210","https://openalex.org/W1754492430","https://openalex.org/W1881372720","https://openalex.org/W1892267472","https://openalex.org/W1964612704","https://openalex.org/W1970815708","https://openalex.org/W1971541031","https://openalex.org/W1973305670","https://openalex.org/W1973323572","https://openalex.org/W1973866091","https://openalex.org/W1976040120","https://openalex.org/W1976631926","https://openalex.org/W1978263877","https://openalex.org/W1980166477","https://openalex.org/W1980322229","https://openalex.org/W1983505512","https://openalex.org/W1984754431","https://openalex.org/W1987808619","https://openalex.org/W1988164635","https://openalex.org/W1991339054","https://openalex.org/W1991607636","https://openalex.org/W1992410904","https://openalex.org/W1994489278","https://openalex.org/W1995912001","https://openalex.org/W1995985888","https://openalex.org/W1997302299","https://openalex.org/W1999555597","https://openalex.org/W2000312484","https://openalex.org/W2000646745","https://openalex.org/W2002787836","https://openalex.org/W2004574444","https://openalex.org/W2008543573","https://openalex.org/W2008941968","https://openalex.org/W2009039171","https://openalex.org/W2011600879","https://openalex.org/W2012341674","https://openalex.org/W2013738116","https://openalex.org/W2015608109","https://openalex.org/W2015666873","https://openalex.org/W2017553046","https://openalex.org/W2017942466","https://openalex.org/W2021955016","https://openalex.org/W2026452617","https://openalex.org/W2027349138","https://openalex.org/W2028306050","https://openalex.org/W2032778685","https://openalex.org/W2037355966","https://openalex.org/W2037916079","https://openalex.org/W2042610505","https://openalex.org/W2051218097","https://openalex.org/W2054973614","https://openalex.org/W2055367307","https://openalex.org/W2056004773","https://openalex.org/W2056830037","https://openalex.org/W2057567296","https://openalex.org/W2058491719","https://openalex.org/W2061217332","https://openalex.org/W2072083281","https://openalex.org/W2074532143","https://openalex.org/W2077683776","https://openalex.org/W2078557912","https://openalex.org/W2084744139","https://openalex.org/W2086472984","https://openalex.org/W2088988616","https://openalex.org/W2091998408","https://openalex.org/W2094629947","https://openalex.org/W2095295932","https://openalex.org/W2099500003","https://openalex.org/W2106500955","https://openalex.org/W2108119444","https://openalex.org/W2108509841","https://openalex.org/W2108717583","https://openalex.org/W2114308764","https://openalex.org/W2117487947","https://openalex.org/W2118174826","https://openalex.org/W2120452314","https://openalex.org/W2120900992","https://openalex.org/W2125928463","https://openalex.org/W2128437316","https://openalex.org/W2128900679","https://openalex.org/W2130450545","https://openalex.org/W2131503256","https://openalex.org/W2132957662","https://openalex.org/W2133220149","https://openalex.org/W2135363210","https://openalex.org/W2136623476","https://openalex.org/W2137554777","https://openalex.org/W2140203893","https://openalex.org/W2140453306","https://openalex.org/W2141533734","https://openalex.org/W2141892948","https://openalex.org/W2148432038","https://openalex.org/W2160546696","https://openalex.org/W2161935351","https://openalex.org/W2163119323","https://openalex.org/W2163504095","https://openalex.org/W2164955616","https://openalex.org/W2166633650","https://openalex.org/W2167037016","https://openalex.org/W2169153064","https://openalex.org/W2178886705","https://openalex.org/W2321419401","https://openalex.org/W2324146181","https://openalex.org/W2510395267","https://openalex.org/W2522040761","https://openalex.org/W2526501053","https://openalex.org/W4249424055","https://openalex.org/W4255217840","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2308947644","https://openalex.org/W176584288","https://openalex.org/W2068798764","https://openalex.org/W2105814774","https://openalex.org/W99249906","https://openalex.org/W2074224463","https://openalex.org/W1520412916","https://openalex.org/W2026222731","https://openalex.org/W3157102586","https://openalex.org/W2136727913"],"abstract_inverted_index":{"Ca2+":[0,53,137,171,239,247,250],"is":[1,139,172],"a":[2,71,78,95,101,153,209,245],"ubiquitous":[3],"second":[4,266],"messenger":[5],"in":[6,21,44,52,68,82,97,103,131,147,175,188,195,205,212,244,282,296],"plant":[7,89],"cell":[8,35,84,105,149,197],"signalling.":[9,64],"In":[10],"this":[11],"review":[12],"we":[13],"consider":[14],"the":[15,31,39,48,88,127,132,142,213,232,238,252,255,259,262,272,290],"role":[16],"of":[17,33,41,50,74,80,124,134,156,230,234,254,258,264,293],"Ca2+\u2010based":[18,157],"signal":[19,120,159,178,214,248],"transduction":[20,160,215],"stomatal":[22,98,162,186,222],"guard":[23,34,45,83,104,108,148,196,285],"cells":[24,109,286],"focusing":[25],"on":[26],"three":[27],"important":[28],"areas:":[29],"(1)":[30],"regulation":[32],"turgor":[36],"relations":[37],"and":[38,58,164,224,261,275],"control":[40,49],"gene":[42],"expression":[43],"cells,":[46],"(2)":[47],"specificity":[51],"signalling,":[54],"(3)":[55],"emerging":[56,273],"technologies":[57,274],"new":[59,276],"approaches":[60,277],"for":[61],"studying":[62],"intracellular":[63],"Stomatal":[65],"apertures":[66],"alter":[67],"response":[69],"to":[70,113,116,126,141,190,287],"wide":[72],"array":[73],"environmental":[75,182],"stimuli":[76,183,219],"as":[77],"result":[79],"changes":[81,146],"turgor.":[85,106,150],"For":[86],"example,":[87],"hormone":[90],"abscisic":[91],"acid":[92],"(ABA)":[93],"stimulates":[94],"reduction":[96],"aperture":[99],"through":[100],"decrease":[102],"Furthermore,":[107],"have":[110],"been":[111],"shown":[112],"be":[114,208,280],"competent":[115],"relay":[117],"an":[118,193],"ABA":[119,158,176],"from":[121],"its":[122],"site":[123],"perception":[125],"nucleus.":[128],"An":[129],"increase":[130,194],"concentration":[133],"cytosolic":[135],"free":[136],"([Ca2+]1)":[138],"central":[140],"mechanisms":[143,229,292],"underlying":[144],"ABA\u2010induced":[145],"We":[151,226,268],"describe":[152],"possible":[154],"model":[155],"during":[161],"closure":[163],"discuss":[165,227],"recent":[166],"evidence":[167],"which":[168,184,218,278],"suggests":[169],"that":[170],"also":[173],"involved":[174],"nuclear":[177],"transduction.":[179],"Many":[180],"other":[181,265],"affect":[185],"apertures,":[187],"addition":[189],"ABA,":[191],"induce":[192],"[Ca2+]1)":[198,206],"This":[199],"raises":[200],"questions":[201],"regarding":[202],"how":[203],"increases":[204],"can":[207,279],"common":[210],"component":[211],"pathways":[216],"by":[217,270],"cause":[220],"both":[221],"opening":[223],"closure.":[225],"several":[228],"increasing":[231],"amount":[233],"information":[235,243],"contained":[236],"within":[237],"signal,":[240],"including":[241],"encoding":[242],"stimulus\u2010specific":[246],"or":[249],"signature',":[251],"concept":[253],"\u2018physiological":[256],"address\u2019":[257],"cell,":[260],"use":[263],"messengers.":[267],"conclude":[269],"addressing":[271],"used":[281],"conjunction":[283],"with":[284],"dissect":[288],"further":[289],"molecular":[291],"Ca2+\u2010mediated":[294],"signalling":[295],"plants.":[297]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}
