{"id":"https://openalex.org/W2043725929","doi":"https://doi.org/10.3353/omp.9.61","title":"Caries Experience of Fluoride-related and Unrelated Enamel Malformations","display_name":"Caries Experience of Fluoride-related and Unrelated Enamel Malformations","publication_year":2004,"publication_date":"2004-01-01","ids":{"openalex":"https://openalex.org/W2043725929","doi":"https://doi.org/10.3353/omp.9.61","mag":"2043725929"},"language":"en","primary_location":{"id":"doi:10.3353/omp.9.61","doi":"https://doi.org/10.3353/omp.9.61","is_oa":true,"landing_page_url":"https://doi.org/10.3353/omp.9.61","pdf_url":"https://www.jstage.jst.go.jp/article/omp/9/2/9_2_61/_pdf","source":{"id":"https://openalex.org/S130281052","display_name":"Oral Medicine & Pathology","issn_l":"1342-0984","issn":["1342-0984","1882-1537"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oral Medicine & Pathology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2043725929"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.jstage.jst.go.jp/article/omp/9/2/9_2_61/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012305635","display_name":"Yue Nakahara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I35552710","display_name":"Nippon Dental University","ror":"https://ror.org/01s1hm369","country_code":"JP","type":"education","lineage":["https://openalex.org/I35552710"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yue Nakahara","raw_affiliation_strings":["General Dentistry 1, The Nippon Dental University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"General Dentistry 1, The Nippon Dental University","institution_ids":["https://openalex.org/I35552710"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Kaori Sato","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I35552710","display_name":"Nippon Dental University","ror":"https://ror.org/01s1hm369","country_code":"JP","type":"education","lineage":["https://openalex.org/I35552710"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kaori Sato","raw_affiliation_strings":["Department of Pathology, The Nippon Dental University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The Nippon Dental University","institution_ids":["https://openalex.org/I35552710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000845980","display_name":"Hisao Yagishita","orcid":"https://orcid.org/0000-0003-4697-5092","observed_orcids":["https://orcid.org/0000-0003-4697-5092"]},"institutions":[{"id":"https://openalex.org/I35552710","display_name":"Nippon Dental University","ror":"https://ror.org/01s1hm369","country_code":"JP","type":"education","lineage":["https://openalex.org/I35552710"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hisao Yagishita","raw_affiliation_strings":["Department of Pathology, The Nippon Dental University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The Nippon Dental University","institution_ids":["https://openalex.org/I35552710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067647425","display_name":"Yuuichi Soeno","orcid":"https://orcid.org/0000-0001-8466-6376","observed_orcids":["https://orcid.org/0000-0001-8466-6376"]},"institutions":[{"id":"https://openalex.org/I35552710","display_name":"Nippon Dental University","ror":"https://ror.org/01s1hm369","country_code":"JP","type":"education","lineage":["https://openalex.org/I35552710"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuuichi Soeno","raw_affiliation_strings":["Department of Pathology, The Nippon Dental University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The Nippon Dental University","institution_ids":["https://openalex.org/I35552710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013099735","display_name":"Masaaki Ogawa","orcid":"https://orcid.org/0000-0003-4615-8412","observed_orcids":["https://orcid.org/0000-0003-4615-8412"]},"institutions":[{"id":"https://openalex.org/I35552710","display_name":"Nippon Dental University","ror":"https://ror.org/01s1hm369","country_code":"JP","type":"education","lineage":["https://openalex.org/I35552710"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaaki Ogawa","raw_affiliation_strings":["Dental Research Institute, The Nippon Dental University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dental Research Institute, The Nippon Dental University","institution_ids":["https://openalex.org/I35552710"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076993009","display_name":"Takaaki Aoba","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I35552710","display_name":"Nippon Dental University","ror":"https://ror.org/01s1hm369","country_code":"JP","type":"education","lineage":["https://openalex.org/I35552710"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takaaki Aoba","raw_affiliation_strings":["Department of Pathology, The Nippon Dental University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The Nippon Dental University","institution_ids":["https://openalex.org/I35552710"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I35552710"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"9","issue":"2","first_page":"61","last_page":"66"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10368","display_name":"Dental Health and Care Utilization","score":0.8622999787330627,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10368","display_name":"Dental Health and Care Utilization","score":0.8622999787330627,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11919","display_name":"dental development and anomalies","score":0.10740000009536743,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11969","display_name":"Fluoride Effects and Removal","score":0.012199999764561653,"subfield":{"id":"https://openalex.org/subfields/2312","display_name":"Water Science and Technology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dental-caries","display_name":"dental caries","score":0.9380000233650208},{"id":"https://openalex.org/keywords/fluorosis","display_name":"fluorosis","score":0.8159999847412109},{"id":"https://openalex.org/keywords/enamel-opacities","display_name":"enamel opacities","score":0.7329999804496765},{"id":"https://openalex.org/keywords/permanent-premolars","display_name":"permanent premolars","score":0.9120000004768372},{"id":"https://openalex.org/keywords/caries-risk","display_name":"caries risk","score":0.7929999828338623},{"id":"https://openalex.org/keywords/pit-and-fissure-caries","display_name":"pit and fissure caries","score":0.9359999895095825},{"id":"https://openalex.org/keywords/developmental-enamel-defects","display_name":"developmental enamel defects","score":0.7369999885559082}],"concepts":[{"id":"https://openalex.org/C156887251","wikidata":"https://www.wikidata.org/wiki/Q2386424","display_name":"Enamel paint","level":2,"score":0.9381229877471924},{"id":"https://openalex.org/C2780828025","wikidata":"https://www.wikidata.org/wiki/Q44793182","display_name":"Fluoride","level":2,"score":0.856460452079773},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.7201307415962219},{"id":"https://openalex.org/C13483470","wikidata":"https://www.wikidata.org/wiki/Q1470152","display_name":"Coronal plane","level":2,"score":0.5911178588867188},{"id":"https://openalex.org/C2909214062","wikidata":"https://www.wikidata.org/wiki/Q911272","display_name":"Electron probe microanalysis","level":3,"score":0.49345913529396057},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4463891386985779},{"id":"https://openalex.org/C2910355441","wikidata":"https://www.wikidata.org/wiki/Q143942","display_name":"Dental enamel","level":3,"score":0.4129014015197754},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2967855930328369},{"id":"https://openalex.org/C138411078","wikidata":"https://www.wikidata.org/wiki/Q911272","display_name":"Electron microprobe","level":2,"score":0.20514392852783203},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.1264646351337433},{"id":"https://openalex.org/C199289684","wikidata":"https://www.wikidata.org/wiki/Q83353","display_name":"Mineralogy","level":1,"score":0.09364938735961914},{"id":"https://openalex.org/C179104552","wikidata":"https://www.wikidata.org/wiki/Q11165","display_name":"Inorganic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3353/omp.9.61","doi":"https://doi.org/10.3353/omp.9.61","is_oa":true,"landing_page_url":"https://doi.org/10.3353/omp.9.61","pdf_url":"https://www.jstage.jst.go.jp/article/omp/9/2/9_2_61/_pdf","source":{"id":"https://openalex.org/S130281052","display_name":"Oral Medicine & Pathology","issn_l":"1342-0984","issn":["1342-0984","1882-1537"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oral Medicine & Pathology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.3353/omp.9.61","doi":"https://doi.org/10.3353/omp.9.61","is_oa":true,"landing_page_url":"https://doi.org/10.3353/omp.9.61","pdf_url":"https://www.jstage.jst.go.jp/article/omp/9/2/9_2_61/_pdf","source":{"id":"https://openalex.org/S130281052","display_name":"Oral Medicine & Pathology","issn_l":"1342-0984","issn":["1342-0984","1882-1537"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oral Medicine & Pathology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G1669607355","display_name":"Elucidation of Cellular and Molecular Pathogenesis of Maxillo-Mandibular and Facial Malformation and Disorders : Use of Gene-Modified Mice","funder_award_id":"13307052","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G8382856320","display_name":"\u30e9\u30c3\u30c8\u5207\u6b6f\u306e\u5b9f\u9a13\u7684\u840c\u51fa\u7570\u5e38\u304c\u6b6f\u306e\u5f62\u6210\u3068\u6b6f\u5468\u7d44\u7e54\u306e\u6539\u9020\u306b\u53ca\u307c\u3059\u5f71\u97ff","funder_award_id":"13771086","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2043725929.pdf","grobid_xml":"https://content.openalex.org/works/W2043725929.grobid-xml"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W81298599","https://openalex.org/W1962450038","https://openalex.org/W1971892542","https://openalex.org/W1978646894","https://openalex.org/W2012969599","https://openalex.org/W2014894683","https://openalex.org/W2020904343","https://openalex.org/W2048993238","https://openalex.org/W2078895787","https://openalex.org/W2092610501","https://openalex.org/W2095831758","https://openalex.org/W2144565447","https://openalex.org/W2271995345"],"related_works":["https://openalex.org/W1966305872","https://openalex.org/W2031277722","https://openalex.org/W2891731032","https://openalex.org/W2074155909","https://openalex.org/W2109905479","https://openalex.org/W2412106975","https://openalex.org/W2030498980","https://openalex.org/W4361005948","https://openalex.org/W130086258","https://openalex.org/W4241656759"],"abstract_inverted_index":{"The":[0,101],"present":[1,102],"study":[2],"aimed":[3],"at":[4],"investigating":[5],"whether":[6,26],"part":[7],"of":[8,22,35,49,97,135],"the":[9,66,116,120],"enamel":[10,45,50,74,79,85,99,128],"opacities":[11],"found":[12],"in":[13,31,112,138,148],"20":[14],"permanent":[15],"premolars":[16,68],"could":[17],"be":[18],"ascribed":[19],"to":[20],"uptake":[21],"excess":[23],"fluoride":[24],"and":[25,33,42,63,84,150],"there":[27,107],"are":[28],"appreciable":[29],"differences":[30,111],"prevalence":[32],"progression":[34],"dental":[36],"caries":[37,113,136,143],"between":[38,115],"tooth":[39,117],"groups":[40,118],"with":[41,80,86,131],"without":[43,75],"developmental":[44,76,88,98],"defects.":[46],"Fluoride":[47],"content":[48],"was":[51],"assessed":[52],"by":[53],"electron":[54],"probe":[55],"microanalysis.":[56],"Based":[57],"on":[58],"visual":[59],"inspection,":[60],"F/Ca":[61],"determination,":[62],"histopathologic":[64,103],"examination,":[65],"pooled":[67],"were":[69,108],"divided":[70],"into":[71],"three":[72],"groups:":[73],"defects":[77,82,89],"(n=6),":[78,83],"fluoride-relative":[81],"fluorotic-irrelative":[87],"(n=8).":[90],"This":[91],"data":[92],"shows":[93],"a":[94,132],"high":[95],"incidence":[96],"malformations.":[100],"findings":[104],"indicate":[105],"that":[106,125],"no":[109],"significant":[110],"experience":[114],"regarding":[119],"entire":[121],"coronal":[122],"enamel,":[123],"but":[124],"mild":[126],"fluorotic":[127],"is":[129],"associated":[130],"lower":[133],"risk":[134],"susceptibility":[137],"these":[139],"smooth":[140],"surfaces,":[141],"while":[142],"development":[144],"still":[145],"remains":[146],"predominant":[147],"pits":[149],"fissures.":[151]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}