{"id":"https://openalex.org/W2043629763","doi":"https://doi.org/10.1007/bf00495139","title":"Simplified purification and testing of colloidal gold probes","display_name":"Simplified purification and testing of colloidal gold probes","publication_year":1985,"publication_date":"1985-01-01","ids":{"openalex":"https://openalex.org/W2043629763","doi":"https://doi.org/10.1007/bf00495139","mag":"2043629763","pmid":"https://pubmed.ncbi.nlm.nih.gov/3900012"},"language":"en","primary_location":{"id":"doi:10.1007/bf00495139","doi":"https://doi.org/10.1007/bf00495139","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00495139","pdf_url":null,"source":{"id":"https://openalex.org/S78725770","display_name":"Histochemistry and Cell Biology","issn_l":"0948-6143","issn":["0948-6143","1432-119X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Histochemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081804406","display_name":"Bao -Le Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Bao -Le Wang","raw_affiliation_strings":["Unit of Histochemistry, University Institute of Pathological Anatomy, Frederik den V's vej 11, DK-2100, Copenhagen \u00d8, Denmark","WHO fellow from Shaanxi Academy of Traditional Chinese Medicine,\n        Unit of Histochemistry, University Institute of Pathological Anatomy, Frederik den V's vej 11, DK-2100, Copenhagen \u00d8, Denmark","Unit of Histochemistry, University Institute of Pathological Anatomy, Copenhagen \u00d8, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit of Histochemistry, University Institute of Pathological Anatomy, Frederik den V's vej 11, DK-2100, Copenhagen \u00d8, Denmark","institution_ids":["https://openalex.org/I124055696"]},{"raw_affiliation_string":"WHO fellow from Shaanxi Academy of Traditional Chinese Medicine,\n        Unit of Histochemistry, University Institute of Pathological Anatomy, Frederik den V's vej 11, DK-2100, Copenhagen \u00d8, Denmark","institution_ids":["https://openalex.org/I124055696"]},{"raw_affiliation_string":"Unit of Histochemistry, University Institute of Pathological Anatomy, Copenhagen \u00d8, Denmark","institution_ids":["https://openalex.org/I124055696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087682022","display_name":"Lucio Scopsi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"L. Scopsi","raw_affiliation_strings":["Unit of Histochemistry, University Institute of Pathological Anatomy, Frederik den V's vej 11, DK-2100, Copenhagen \u00d8, Denmark","WHO fellow from Shaanxi Academy of Traditional Chinese Medicine,\n        Unit of Histochemistry, University Institute of Pathological Anatomy, Frederik den V's vej 11, DK-2100, Copenhagen \u00d8, Denmark","Unit of Histochemistry, University Institute of Pathological Anatomy, Copenhagen \u00d8, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit of Histochemistry, University Institute of Pathological Anatomy, Frederik den V's vej 11, DK-2100, Copenhagen \u00d8, Denmark","institution_ids":["https://openalex.org/I124055696"]},{"raw_affiliation_string":"WHO fellow from Shaanxi Academy of Traditional Chinese Medicine,\n        Unit of Histochemistry, University Institute of Pathological Anatomy, Frederik den V's vej 11, DK-2100, Copenhagen \u00d8, Denmark","institution_ids":["https://openalex.org/I124055696"]},{"raw_affiliation_string":"Unit of Histochemistry, University Institute of Pathological Anatomy, Copenhagen \u00d8, Denmark","institution_ids":["https://openalex.org/I124055696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103382798","display_name":"Morten H. Nielsen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"M. Hartvig Nielsen","raw_affiliation_strings":["Unit of Histochemistry, University Institute of Pathological Anatomy, Frederik den V's vej 11, DK-2100, Copenhagen \u00d8, Denmark","WHO fellow from Shaanxi Academy of Traditional Chinese Medicine,\n        Unit of Histochemistry, University Institute of Pathological Anatomy, Frederik den V's vej 11, DK-2100, Copenhagen \u00d8, Denmark","Unit of Histochemistry, University Institute of Pathological Anatomy, Copenhagen \u00d8, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit of Histochemistry, University Institute of Pathological Anatomy, Frederik den V's vej 11, DK-2100, Copenhagen \u00d8, Denmark","institution_ids":["https://openalex.org/I124055696"]},{"raw_affiliation_string":"WHO fellow from Shaanxi Academy of Traditional Chinese Medicine,\n        Unit of Histochemistry, University Institute of Pathological Anatomy, Frederik den V's vej 11, DK-2100, Copenhagen \u00d8, Denmark","institution_ids":["https://openalex.org/I124055696"]},{"raw_affiliation_string":"Unit of Histochemistry, University Institute of Pathological Anatomy, Copenhagen \u00d8, Denmark","institution_ids":["https://openalex.org/I124055696"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059674225","display_name":"Lars Larsson","orcid":"https://orcid.org/0000-0003-3722-035X","observed_orcids":["https://orcid.org/0000-0003-3722-035X"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"L. -I. Larsson","raw_affiliation_strings":["Unit of Histochemistry, University Institute of Pathological Anatomy, Frederik den V's vej 11, DK-2100, Copenhagen \u00d8, Denmark","WHO fellow from Shaanxi Academy of Traditional Chinese Medicine,\n        Unit of Histochemistry, University Institute of Pathological Anatomy, Frederik den V's vej 11, DK-2100, Copenhagen \u00d8, Denmark","Unit of Histochemistry, University Institute of Pathological Anatomy, Copenhagen \u00d8, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit of Histochemistry, University Institute of Pathological Anatomy, Frederik den V's vej 11, DK-2100, Copenhagen \u00d8, Denmark","institution_ids":["https://openalex.org/I124055696"]},{"raw_affiliation_string":"WHO fellow from Shaanxi Academy of Traditional Chinese Medicine,\n        Unit of Histochemistry, University Institute of Pathological Anatomy, Frederik den V's vej 11, DK-2100, Copenhagen \u00d8, Denmark","institution_ids":["https://openalex.org/I124055696"]},{"raw_affiliation_string":"Unit of Histochemistry, University Institute of Pathological Anatomy, Copenhagen \u00d8, Denmark","institution_ids":["https://openalex.org/I124055696"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I124055696"],"apc_list":{"value":2990,"currency":"USD","value_usd":2990},"apc_paid":null,"fwci":2.1679,"has_fulltext":false,"cited_by_count":35,"citation_normalized_percentile":{"value":0.88035714,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"83","issue":"2","first_page":"109","last_page":"115"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10857","display_name":"Advanced Electron Microscopy Techniques and Applications","score":0.48750001192092896,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10857","display_name":"Advanced Electron Microscopy Techniques and Applications","score":0.48750001192092896,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10131","display_name":"Gold and Silver Nanoparticles Synthesis and Applications","score":0.1168999969959259,"subfield":{"id":"https://openalex.org/subfields/2504","display_name":"Electronic, Optical and Magnetic Materials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14134","display_name":"Classical Anatomy and Histology","score":0.04740000143647194,"subfield":{"id":"https://openalex.org/subfields/2702","display_name":"Anatomy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/size-exclusion-chromatography","display_name":"size exclusion chromatography","score":0.7490000128746033}],"concepts":[{"id":"https://openalex.org/C104819515","wikidata":"https://www.wikidata.org/wiki/Q900961","display_name":"Colloidal gold","level":3,"score":0.8509875535964966},{"id":"https://openalex.org/C197336794","wikidata":"https://www.wikidata.org/wiki/Q5161150","display_name":"Conjugate","level":2,"score":0.7110955715179443},{"id":"https://openalex.org/C2911045874","wikidata":"https://www.wikidata.org/wiki/Q900961","display_name":"Gold Colloid","level":4,"score":0.6123843789100647},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.6109955906867981},{"id":"https://openalex.org/C2776190903","wikidata":"https://www.wikidata.org/wiki/Q421817","display_name":"Streptavidin","level":3,"score":0.5655092000961304},{"id":"https://openalex.org/C166029249","wikidata":"https://www.wikidata.org/wiki/Q3772564","display_name":"Negative stain","level":3,"score":0.5311041474342346},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5285750031471252},{"id":"https://openalex.org/C112613896","wikidata":"https://www.wikidata.org/wiki/Q898370","display_name":"Conjugated system","level":3,"score":0.4235665202140808},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.28507256507873535},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.23159745335578918},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2003365159034729},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.1783086061477661},{"id":"https://openalex.org/C93877712","wikidata":"https://www.wikidata.org/wiki/Q132560","display_name":"Electron microscope","level":2,"score":0.12481597065925598},{"id":"https://openalex.org/C2778204606","wikidata":"https://www.wikidata.org/wiki/Q181354","display_name":"Biotin","level":2,"score":0.10997927188873291},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0681513249874115},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002850","descriptor_name":"Chromatography, Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006046","descriptor_name":"Gold","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D007158","descriptor_name":"Immunologic Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010902","descriptor_name":"Pituitary Gland","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013006","descriptor_name":"Growth Hormone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/bf00495139","doi":"https://doi.org/10.1007/bf00495139","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00495139","pdf_url":null,"source":{"id":"https://openalex.org/S78725770","display_name":"Histochemistry and Cell Biology","issn_l":"0948-6143","issn":["0948-6143","1432-119X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Histochemistry","raw_type":"journal-article"},{"id":"pmid:3900012","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3900012","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Histochemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320323124","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1840515050","https://openalex.org/W2005601587","https://openalex.org/W2010431759","https://openalex.org/W2018778009","https://openalex.org/W2045347287","https://openalex.org/W2085293654","https://openalex.org/W2130592661","https://openalex.org/W2167309585","https://openalex.org/W2401107169","https://openalex.org/W2887197608","https://openalex.org/W3001372012","https://openalex.org/W4234807368"],"related_works":["https://openalex.org/W4240283844","https://openalex.org/W2407977049","https://openalex.org/W2439336087","https://openalex.org/W4238035111","https://openalex.org/W2025221873","https://openalex.org/W1840515050","https://openalex.org/W2409345434","https://openalex.org/W4242433646","https://openalex.org/W1812371611","https://openalex.org/W2005649237"],"abstract_inverted_index":null,"counts_by_year":[{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}