{"id":"https://openalex.org/W2043615730","doi":"https://doi.org/10.1002/jss.400090202","title":"Independence of normal phenotypic properties and cell surface receptor mobility in variant cell lines","display_name":"Independence of normal phenotypic properties and cell surface receptor mobility in variant cell lines","publication_year":1978,"publication_date":"1978-01-01","ids":{"openalex":"https://openalex.org/W2043615730","doi":"https://doi.org/10.1002/jss.400090202","mag":"2043615730","pmid":"https://pubmed.ncbi.nlm.nih.gov/748674"},"language":"en","primary_location":{"id":"doi:10.1002/jss.400090202","doi":"https://doi.org/10.1002/jss.400090202","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jss.400090202","pdf_url":null,"source":{"id":"https://openalex.org/S122364590","display_name":"Journal of Supramolecular Structure","issn_l":"0091-7419","issn":["0091-7419","1547-9366"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Supramolecular Structure","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5106234492","display_name":"Robert E. Williams","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert E. Williams","raw_affiliation_strings":["Department of Microbiology and the Molecular Biology Institute, University of California, Los Angeles, California 90024"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and the Molecular Biology Institute, University of California, Los Angeles, California 90024","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062610230","display_name":"Peter S. Linsley","orcid":"https://orcid.org/0000-0002-8960-4307","observed_orcids":["https://orcid.org/0000-0002-8960-4307"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter S. Linsley","raw_affiliation_strings":["Department of Microbiology and the Molecular Biology Institute, University of California, Los Angeles, California 90024"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and the Molecular Biology Institute, University of California, Los Angeles, California 90024","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078373142","display_name":"Harry G. Rittenhouse","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Harry G. Rittenhouse","raw_affiliation_strings":["Department of Microbiology and the Molecular Biology Institute, University of California, Los Angeles, California 90024"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and the Molecular Biology Institute, University of California, Los Angeles, California 90024","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041490305","display_name":"Colin Fox","orcid":"https://orcid.org/0000-0002-9278-1777","observed_orcids":["https://orcid.org/0000-0002-9278-1777"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. Fred Fox","raw_affiliation_strings":["Department of Microbiology and the Molecular Biology Institute, University of California, Los Angeles, California 90024"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and the Molecular Biology Institute, University of California, Los Angeles, California 90024","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111645316","display_name":"Charles W. Boone","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles W. Boone","raw_affiliation_strings":["Cell Biology Section, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20014"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cell Biology Section, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20014","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.09377814,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"9","issue":"2","first_page":"147","last_page":"156"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.4187000095844269,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.4187000095844269,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.20909999310970306,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.19689999520778656,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/malignant-transformation","display_name":"malignant transformation","score":0.8970000147819519},{"id":"https://openalex.org/keywords/transformed-phenotype","display_name":"transformed phenotype","score":0.6039999723434448},{"id":"https://openalex.org/keywords/receptor-dynamics","display_name":"receptor dynamics","score":0.4189999997615814},{"id":"https://openalex.org/keywords/cell-surface-receptors","display_name":"cell surface receptors","score":0.34299999475479126}],"concepts":[{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.7626197338104248},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.6592494249343872},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.6469323635101318},{"id":"https://openalex.org/C35651441","wikidata":"https://www.wikidata.org/wiki/Q625303","display_name":"Independence (probability theory)","level":2,"score":0.6021844744682312},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5773552656173706},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5137728452682495},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.5032145380973816},{"id":"https://openalex.org/C197462201","wikidata":"https://www.wikidata.org/wiki/Q2476074","display_name":"Cell surface receptor","level":3,"score":0.4787658751010895},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3782527446746826},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2023773193359375},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1420237421989441},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1065237820148468},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002471","descriptor_name":"Cell Transformation, Neoplastic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008560","descriptor_name":"Membrane Fluidity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009374","descriptor_name":"Neoplasms, Experimental","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011952","descriptor_name":"Receptors, Concanavalin A","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011955","descriptor_name":"Receptors, Drug","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1002/jss.400090202","doi":"https://doi.org/10.1002/jss.400090202","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jss.400090202","pdf_url":null,"source":{"id":"https://openalex.org/S122364590","display_name":"Journal of Supramolecular Structure","issn_l":"0091-7419","issn":["0091-7419","1547-9366"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Supramolecular Structure","raw_type":"journal-article"},{"id":"pmid:748674","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/748674","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of supramolecular structure","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W594356966","https://openalex.org/W1440600210","https://openalex.org/W1546875512","https://openalex.org/W1970894749","https://openalex.org/W1973460681","https://openalex.org/W1974013623","https://openalex.org/W1976237896","https://openalex.org/W1991293003","https://openalex.org/W2005645305","https://openalex.org/W2012506514","https://openalex.org/W2017809573","https://openalex.org/W2023887187","https://openalex.org/W2027416047","https://openalex.org/W2040147733","https://openalex.org/W2056819614","https://openalex.org/W2070378812","https://openalex.org/W2084722791","https://openalex.org/W2088719153","https://openalex.org/W2503923837"],"related_works":["https://openalex.org/W2089658382","https://openalex.org/W1583780191","https://openalex.org/W56507488","https://openalex.org/W2462539524","https://openalex.org/W2271204144","https://openalex.org/W3036837204","https://openalex.org/W2418202836","https://openalex.org/W3036089237","https://openalex.org/W2415259296","https://openalex.org/W1874652601"],"abstract_inverted_index":{"We":[0],"report":[1],"the":[2,10,20,32,35],"use":[3],"of":[4,7,23,34],"three":[5],"classes":[6],"variants":[8],"from":[9],"long-established,":[11],"malignantly":[12],"transformed":[13,36],"LM":[14],"cell":[15,24],"line":[16],"to":[17],"demonstrate":[18],"that":[19],"apparent":[21],"mobility":[22],"surface":[25],"receptors":[26],"need":[27],"not":[28],"be":[29],"dependent":[30],"on":[31],"expression":[33],"phenotype":[37],"in":[38],"vitro.":[39]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}