{"id":"https://openalex.org/W2043577874","doi":"https://doi.org/10.1186/1471-2377-13-205","title":"Study protocol to examine the effects of spaceflight and a spaceflight analog on neurocognitive performance: extent, longevity, and neural bases","display_name":"Study protocol to examine the effects of spaceflight and a spaceflight analog on neurocognitive performance: extent, longevity, and neural bases","publication_year":2013,"publication_date":"2013-12-01","ids":{"openalex":"https://openalex.org/W2043577874","doi":"https://doi.org/10.1186/1471-2377-13-205","mag":"2043577874","pmid":"https://pubmed.ncbi.nlm.nih.gov/24350728","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3878338"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2377-13-205","doi":"https://doi.org/10.1186/1471-2377-13-205","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2377-13-205","pdf_url":"https://bmcneurol.biomedcentral.com/counter/pdf/10.1186/1471-2377-13-205","source":{"id":"https://openalex.org/S120289491","display_name":"BMC Neurology","issn_l":"1471-2377","issn":["1471-2377"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Neurology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcneurol.biomedcentral.com/counter/pdf/10.1186/1471-2377-13-205","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010182234","display_name":"Vincent Koppelmans","orcid":"https://orcid.org/0000-0003-2036-7603","observed_orcids":["https://orcid.org/0000-0003-2036-7603"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vincent Koppelmans","raw_affiliation_strings":["School of Kinesiology, University of Michigan, Ann Arbor, MI, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Kinesiology, University of Michigan, Ann Arbor, MI, USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067890186","display_name":"Burak Erdeniz","orcid":"https://orcid.org/0000-0002-5517-5022","observed_orcids":["https://orcid.org/0000-0002-5517-5022"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Burak Erdeniz","raw_affiliation_strings":["School of Kinesiology, University of Michigan, Ann Arbor, MI, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Kinesiology, University of Michigan, Ann Arbor, MI, USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047120883","display_name":"Yiri E. De Dios","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yiri E De Dios","raw_affiliation_strings":["Wyle Life Sciences, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wyle Life Sciences, Houston, TX, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068528906","display_name":"Scott J. Wood","orcid":"https://orcid.org/0000-0002-2603-7552","observed_orcids":["https://orcid.org/0000-0002-2603-7552"]},"institutions":[{"id":"https://openalex.org/I4210149382","display_name":"Johnson Space Center","ror":"https://ror.org/04xx4z452","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210124779","https://openalex.org/I4210149382"]},{"id":"https://openalex.org/I96408169","display_name":"Azusa Pacific University","ror":"https://ror.org/02bmftj86","country_code":"US","type":"education","lineage":["https://openalex.org/I96408169"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott J Wood","raw_affiliation_strings":["College of Liberal Arts and Sciences, Pacific Azusa University, Los Angeles, CA, USA","NASA Johnson Space Center, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Liberal Arts and Sciences, Pacific Azusa University, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I96408169"]},{"raw_affiliation_string":"NASA Johnson Space Center, Houston, TX, USA","institution_ids":["https://openalex.org/I4210149382"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069572757","display_name":"Patricia A. Reuter\u2010Lorenz","orcid":"https://orcid.org/0000-0002-6977-3429","observed_orcids":["https://orcid.org/0000-0002-6977-3429"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patricia A Reuter-Lorenz","raw_affiliation_strings":["Department of Psychology, University of Michigan, Ann Arbor, MI, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, University of Michigan, Ann Arbor, MI, USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112497779","display_name":"Igor S. Kofman","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Igor Kofman","raw_affiliation_strings":["Wyle Life Sciences, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wyle Life Sciences, Houston, TX, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023164694","display_name":"Jacob J. Bloomberg","orcid":"https://orcid.org/0000-0003-2774-2699","observed_orcids":["https://orcid.org/0000-0003-2774-2699"]},"institutions":[{"id":"https://openalex.org/I4210149382","display_name":"Johnson Space Center","ror":"https://ror.org/04xx4z452","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210124779","https://openalex.org/I4210149382"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jacob J Bloomberg","raw_affiliation_strings":["Neuroscience Laboratory, NASA Johnson Space Center, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuroscience Laboratory, NASA Johnson Space Center, Houston, TX, USA","institution_ids":["https://openalex.org/I4210149382"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076998935","display_name":"Ajitkumar P. Mulavara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1329765538","display_name":"Universities Space Research Association","ror":"https://ror.org/043pgqy52","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1329765538"]},{"id":"https://openalex.org/I4210149382","display_name":"Johnson Space Center","ror":"https://ror.org/04xx4z452","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210124779","https://openalex.org/I4210149382"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ajitkumar P Mulavara","raw_affiliation_strings":["Neuroscience Laboratory, NASA Johnson Space Center, Houston, TX, USA","Universities Space Research Association, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuroscience Laboratory, NASA Johnson Space Center, Houston, TX, USA","institution_ids":["https://openalex.org/I4210149382"]},{"raw_affiliation_string":"Universities Space Research Association, Houston, TX, USA","institution_ids":["https://openalex.org/I1329765538"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026777353","display_name":"Rachael D. Seidler","orcid":"https://orcid.org/0000-0003-2452-9024","observed_orcids":["https://orcid.org/0000-0003-2452-9024"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Rachael D Seidler","raw_affiliation_strings":["School of Kinesiology, University of Michigan, Ann Arbor MI, USA. rseidler@umich.edu","Department of Psychology, University of Michigan, Ann Arbor, MI, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Kinesiology, University of Michigan, Ann Arbor MI, USA. rseidler@umich.edu","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Department of Psychology, University of Michigan, Ann Arbor, MI, USA","institution_ids":["https://openalex.org/I27837315"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5026777353"],"corresponding_institution_ids":["https://openalex.org/I27837315"],"apc_list":{"value":3090,"currency":"USD","value_usd":3090},"apc_paid":{"value":3090,"currency":"USD","value_usd":3090},"fwci":3.4593,"has_fulltext":true,"cited_by_count":88,"citation_normalized_percentile":{"value":0.91909265,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"13","issue":"1","first_page":"205","last_page":"205"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12005","display_name":"Spaceflight effects on biology","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12005","display_name":"Spaceflight effects on biology","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14214","display_name":"Space Exploration and Technology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2202","display_name":"Aerospace Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11950","display_name":"Cardiovascular Syncope and Autonomic Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/long-duration-spaceflight","display_name":"long-duration spaceflight","score":0.8759999871253967},{"id":"https://openalex.org/keywords/microgravity","display_name":"microgravity","score":0.7559999823570251},{"id":"https://openalex.org/keywords/neuropsychological-performance","display_name":"neuropsychological performance","score":0.9470000267028809},{"id":"https://openalex.org/keywords/sensorimotor-adaptation","display_name":"sensorimotor adaptation","score":0.8100000023841858},{"id":"https://openalex.org/keywords/head-down-bed-rest","display_name":"head-down bed rest","score":0.6660000085830688},{"id":"https://openalex.org/keywords/astronauts","display_name":"astronauts","score":0.6669999957084656},{"id":"https://openalex.org/keywords/spatial-working-memory","display_name":"spatial working memory","score":0.8119999766349792},{"id":"https://openalex.org/keywords/fine-motor-control","display_name":"fine motor control","score":0.9729999899864197},{"id":"https://openalex.org/keywords/gait-and-balance","display_name":"gait and balance","score":0.8529999852180481},{"id":"https://openalex.org/keywords/brain-structure-and-function","display_name":"brain structure and function","score":0.7549999952316284},{"id":"https://openalex.org/keywords/functional-connectivity","display_name":"functional connectivity","score":0.7620000243186951},{"id":"https://openalex.org/keywords/countermeasures","display_name":"countermeasures","score":0.6060000061988831}],"concepts":[{"id":"https://openalex.org/C103888896","wikidata":"https://www.wikidata.org/wiki/Q5916","display_name":"Spaceflight","level":2,"score":0.9822355508804321},{"id":"https://openalex.org/C172467417","wikidata":"https://www.wikidata.org/wiki/Q1670397","display_name":"Neurocognitive","level":3,"score":0.6213511228561401},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.5489099025726318},{"id":"https://openalex.org/C16568411","wikidata":"https://www.wikidata.org/wiki/Q83042","display_name":"Neurology","level":2,"score":0.47483688592910767},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.47355690598487854},{"id":"https://openalex.org/C6439246","wikidata":"https://www.wikidata.org/wiki/Q3332475","display_name":"Aviation medicine","level":2,"score":0.4462248682975769},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.44543883204460144},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.37999382615089417},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.3411060571670532},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.24295228719711304},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.15260261297225952},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C146978453","wikidata":"https://www.wikidata.org/wiki/Q3798668","display_name":"Aerospace engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000337","descriptor_name":"Aerospace Medicine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001510","descriptor_name":"Bed Rest","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008124","descriptor_name":"Locomotion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008570","descriptor_name":"Memory, Short-Term","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011187","descriptor_name":"Posture","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011597","descriptor_name":"Psychomotor Performance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013026","descriptor_name":"Space Flight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014893","descriptor_name":"Weightlessness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018480","descriptor_name":"Astronauts","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D038524","descriptor_name":"Diffusion Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055806","descriptor_name":"Microvessels","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058585","descriptor_name":"Vestibular Evoked Myogenic Potentials","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/1471-2377-13-205","doi":"https://doi.org/10.1186/1471-2377-13-205","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2377-13-205","pdf_url":"https://bmcneurol.biomedcentral.com/counter/pdf/10.1186/1471-2377-13-205","source":{"id":"https://openalex.org/S120289491","display_name":"BMC Neurology","issn_l":"1471-2377","issn":["1471-2377"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Neurology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3878338","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3878338","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Neurol","raw_type":"Text"},{"id":"pmid:24350728","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24350728","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC neurology","raw_type":"Journal Article"},{"id":"pmh:oai:deepblue.lib.umich.edu:2027.42/112560","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/2027.42/112560","pdf_url":null,"source":{"id":"https://openalex.org/S4306400393","display_name":"Deep Blue (University of Michigan)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I27837315","host_organization_name":"University of Michigan","host_organization_lineage":["https://openalex.org/I27837315"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1186/1471-2377-13-205","doi":"https://doi.org/10.1186/1471-2377-13-205","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2377-13-205","pdf_url":"https://bmcneurol.biomedcentral.com/counter/pdf/10.1186/1471-2377-13-205","source":{"id":"https://openalex.org/S120289491","display_name":"BMC Neurology","issn_l":"1471-2377","issn":["1471-2377"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Neurology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Study Protocol","id":"https://openalex.org/study-designs/study-protocol"}],"awards":[{"id":"https://openalex.org/G1876006324","display_name":null,"funder_award_id":"NNX11AR02G","funder_id":"https://openalex.org/F4320310845","funder_display_name":"National Space Biomedical Research Institute"},{"id":"https://openalex.org/G2641706501","display_name":"NRA NNJ10ZSA003N REQUESTS PROPOSALS TO ASSESS CHANGES IN ELEMENTAL NEUROCOGNITIVE FUNCTIONS SUCH AS PERCEPTION, MOTOR CONTROL, MEMORY, ATTENTION, LAN","funder_award_id":"NNX11AR02G","funder_id":"https://openalex.org/F4320306101","funder_display_name":"National Aeronautics and Space Administration"},{"id":"https://openalex.org/G7919359904","display_name":"NATIONAL SPACE BIOMEDICAL RESEARCH INSTITUTE","funder_award_id":"NCC958","funder_id":"https://openalex.org/F4320306101","funder_display_name":"National Aeronautics and Space Administration"},{"id":"https://openalex.org/G816501378","display_name":null,"funder_award_id":"NCC 9\u201058","funder_id":"https://openalex.org/F4320310845","funder_display_name":"National Space Biomedical Research Institute"}],"funders":[{"id":"https://openalex.org/F4320306101","display_name":"National Aeronautics and Space Administration","ror":"https://ror.org/027ka1x80"},{"id":"https://openalex.org/F4320310845","display_name":"National Space Biomedical Research Institute","ror":"https://ror.org/04731xt44"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2043577874.pdf","grobid_xml":"https://content.openalex.org/works/W2043577874.grobid-xml"},"referenced_works_count":84,"referenced_works":["https://openalex.org/W155756870","https://openalex.org/W266846624","https://openalex.org/W301068150","https://openalex.org/W621737207","https://openalex.org/W819061666","https://openalex.org/W1228390363","https://openalex.org/W1241618940","https://openalex.org/W1276530583","https://openalex.org/W1506973712","https://openalex.org/W1535368408","https://openalex.org/W1535898435","https://openalex.org/W1566228707","https://openalex.org/W1573689483","https://openalex.org/W1606396337","https://openalex.org/W1761213051","https://openalex.org/W1966394781","https://openalex.org/W1966471108","https://openalex.org/W1970475719","https://openalex.org/W1971354911","https://openalex.org/W1972289455","https://openalex.org/W1973389165","https://openalex.org/W1977494471","https://openalex.org/W1979732149","https://openalex.org/W1984830801","https://openalex.org/W1988920269","https://openalex.org/W1990257603","https://openalex.org/W2001972701","https://openalex.org/W2002114414","https://openalex.org/W2003859140","https://openalex.org/W2010082462","https://openalex.org/W2010567388","https://openalex.org/W2013669877","https://openalex.org/W2014759754","https://openalex.org/W2014911231","https://openalex.org/W2017318064","https://openalex.org/W2018253362","https://openalex.org/W2020124179","https://openalex.org/W2023519311","https://openalex.org/W2025850085","https://openalex.org/W2029472570","https://openalex.org/W2029644254","https://openalex.org/W2032011764","https://openalex.org/W2041640295","https://openalex.org/W2041736105","https://openalex.org/W2041880054","https://openalex.org/W2046026874","https://openalex.org/W2047298432","https://openalex.org/W2048878685","https://openalex.org/W2049273156","https://openalex.org/W2052246599","https://openalex.org/W2062678263","https://openalex.org/W2065359939","https://openalex.org/W2065879030","https://openalex.org/W2090608960","https://openalex.org/W2094475339","https://openalex.org/W2102352389","https://openalex.org/W2112862038","https://openalex.org/W2116223414","https://openalex.org/W2121271502","https://openalex.org/W2125657871","https://openalex.org/W2127645750","https://openalex.org/W2131320161","https://openalex.org/W2136935850","https://openalex.org/W2139581313","https://openalex.org/W2145610370","https://openalex.org/W2148163686","https://openalex.org/W2149596806","https://openalex.org/W2151316811","https://openalex.org/W2153038533","https://openalex.org/W2155376855","https://openalex.org/W2157684416","https://openalex.org/W2162094883","https://openalex.org/W2162403063","https://openalex.org/W2335718677","https://openalex.org/W2397035679","https://openalex.org/W2409280500","https://openalex.org/W2418092182","https://openalex.org/W3145636315","https://openalex.org/W4235412292","https://openalex.org/W4240508805","https://openalex.org/W4285719527","https://openalex.org/W4301055647","https://openalex.org/W4388321743","https://openalex.org/W4413112698"],"related_works":["https://openalex.org/W751475383","https://openalex.org/W6980162840","https://openalex.org/W6983722540","https://openalex.org/W6981384038","https://openalex.org/W1602004555","https://openalex.org/W1501177375","https://openalex.org/W6990738553","https://openalex.org/W1500049153","https://openalex.org/W2470339889","https://openalex.org/W2610707033"],"abstract_inverted_index":{"BACKGROUND:":[0],"Long":[1],"duration":[2],"spaceflight":[3,39,44,89,138,168,323],"(i.e.,":[4],"22":[5],"days":[6,192],"or":[7],"longer)":[8],"has":[9],"been":[10],"associated":[11],"with":[12,23,132],"changes":[13,302,326],"in":[14,18,62,145,249,334],"sensorimotor":[15,41,98,295],"systems,":[16],"resulting":[17],"difficulties":[19],"that":[20,282],"astronauts":[21,146,275],"experience":[22],"posture":[24],"control,":[25,257],"locomotion,":[26],"and":[27,67,73,94,99,161,212,243,266,286,297,305,310,313],"manual":[28],"control.":[29],"The":[30,135],"microgravity":[31,179],"environment":[32],"is":[33,55,129],"an":[34],"important":[35],"causal":[36],"factor":[37],"for":[38,124],"induced":[40,324],"changes.":[42,102],"Whether":[43],"also":[45],"affects":[46],"other":[47],"central":[48],"nervous":[49],"system":[50],"functions":[51],"such":[52],"as":[53],"cognition":[54],"yet":[56],"largely":[57],"unknown,":[58],"but":[59],"of":[60,64,69,88,97,108,137,170,178,184,190,221,235,252,279,337,345],"importance":[61],"consideration":[63],"the":[65,86,91,106,127,140,176,181,188,280,335,342],"health":[66],"performance":[68,101],"crewmembers":[70],"both":[71],"in-":[72],"post-flight.":[74],"We":[75],"are":[76],"therefore":[77],"conducting":[78],"a":[79,167],"controlled":[80],"prospective":[81],"longitudinal":[82],"study":[83,113,320],"to":[84,232,340],"investigate":[85,187],"effects":[87,136,183,189,344],"on":[90,139],"extent,":[92],"longevity":[93],"neural":[95],"bases":[96],"cognitive":[100],"Here":[103],"we":[104,186],"present":[105],"protocol":[107],"our":[109,236],"study.":[110],"METHODS/DESIGN:":[111],"This":[112,319,330],"includes":[114],"three":[115,157,213],"groups":[116],"(astronauts,":[117],"bed":[118,195],"rest":[119,198],"subjects,":[120],"ground-based":[121],"control":[122],"subjects)":[123],"which":[125],"each":[126],"design":[128,336],"single":[130],"group":[131,220],"repeated":[133],"measures.":[134],"brain":[141,311,325],"will":[142,148,200,225,270,276,315],"be":[143,149,201,226,271,316],"investigated":[144],"who":[147],"assessed":[150,202],"at":[151,156,162,203,228,244],"two":[152,204,208],"time":[153,158,164,205,209,214,230,246,304],"points":[154,159,165,206,210,215,231],"pre-,":[155],"during-,":[160,211],"four":[163,229],"following":[166],"mission":[169],"six":[171],"months.":[172],"To":[173],"parse":[174],"out":[175],"effect":[177],"from":[180],"overall":[182],"spaceflight,":[185],"seventy":[191],"head-down":[193],"tilted":[194],"rest.":[196,217],"Bed":[197],"subjects":[199],"before-,":[207],"post-bed":[216],"A":[218],"third":[219],"ground":[222],"based":[223],"controls":[224],"measured":[227],"assess":[233],"reliability":[234],"measures":[237,251],"over":[238,303],"time.":[239],"For":[240],"all":[241,245],"participants":[242],"points,":[247],"except":[248],"flight,":[250,274,288],"neurocognitive":[253],"performance,":[254],"fine":[255,298],"motor":[256,299],"gait,":[258],"balance,":[259],"structural":[260],"MRI":[261,269],"(T1,":[262],"DTI),":[263],"task":[264],"fMRI,":[265],"functional":[267,328],"connectivity":[268],"obtained.":[272],"In":[273],"complete":[277,284],"some":[278],"tasks":[281,290],"they":[283],"pre-":[285],"post":[287],"including":[289],"measuring":[291],"spatial":[292],"working":[293],"memory,":[294],"adaptation,":[296],"performance.":[300,329],"Potential":[301],"associations":[306],"between":[307],"cognition,":[308],"motor-behavior,":[309],"structure":[312],"function":[314],"analyzed.":[317],"DISCUSSION:":[318],"explores":[321],"how":[322],"impact":[327],"understanding":[331],"could":[332],"aid":[333],"targeted":[338],"countermeasures":[339],"mitigate":[341],"negative":[343],"long-duration":[346],"spaceflight.":[347]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":9}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}