{"id":"https://openalex.org/W2043546261","doi":"https://doi.org/10.1097/01.ccm.0000134263.32657.34","title":"\u03b21-Adrenergic blockade during cardiopulmonary resuscitation improves survival","display_name":"\u03b21-Adrenergic blockade during cardiopulmonary resuscitation improves survival","publication_year":2004,"publication_date":"2004-08-27","ids":{"openalex":"https://openalex.org/W2043546261","doi":"https://doi.org/10.1097/01.ccm.0000134263.32657.34","mag":"2043546261","pmid":"https://pubmed.ncbi.nlm.nih.gov/15508675"},"language":"en","primary_location":{"id":"doi:10.1097/01.ccm.0000134263.32657.34","doi":"https://doi.org/10.1097/01.ccm.0000134263.32657.34","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.ccm.0000134263.32657.34","pdf_url":null,"source":{"id":"https://openalex.org/S108732581","display_name":"Critical Care Medicine","issn_l":"0090-3493","issn":["0090-3493","1530-0293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Care Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5104274380","display_name":"Gianluca Cammarata","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gianluca Cammarata","raw_affiliation_strings":["Institute of Critical Care Medicine, Palm Springs, CA, USA","From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH); Supported, in part, by a Grant-in-Aid to M. H. Weil by the American Heart Association, Dallas, TX, and by grant HL54322 from the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.; the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Critical Care Medicine, Palm Springs, CA, USA","institution_ids":[]},{"raw_affiliation_string":"From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH); Supported, in part, by a Grant-in-Aid to M. H. Weil by the American Heart Association, Dallas, TX, and by grant HL54322 from the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.; the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112800612","display_name":"Max Harry Weil","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Max Harry Weil","raw_affiliation_strings":["From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH)","and the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)","From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH); Supported, in part, by a Grant-in-Aid to M. H. Weil by the American Heart Association, Dallas, TX, and by grant HL54322 from the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.; the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH)","institution_ids":[]},{"raw_affiliation_string":"and the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH); Supported, in part, by a Grant-in-Aid to M. H. Weil by the American Heart Association, Dallas, TX, and by grant HL54322 from the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.; the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104285866","display_name":"Shijie Sun","orcid":"https://orcid.org/0009-0009-0953-8150","observed_orcids":["https://orcid.org/0009-0009-0953-8150"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shijie Sun","raw_affiliation_strings":["From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH)","and the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)","From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH); Supported, in part, by a Grant-in-Aid to M. H. Weil by the American Heart Association, Dallas, TX, and by grant HL54322 from the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.; the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH)","institution_ids":[]},{"raw_affiliation_string":"and the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH); Supported, in part, by a Grant-in-Aid to M. H. Weil by the American Heart Association, Dallas, TX, and by grant HL54322 from the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.; the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037913088","display_name":"Wanchun Tang","orcid":"https://orcid.org/0000-0003-3940-6369","observed_orcids":["https://orcid.org/0000-0003-3940-6369"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wanchun Tang","raw_affiliation_strings":["From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH)","and the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)","From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH); Supported, in part, by a Grant-in-Aid to M. H. Weil by the American Heart Association, Dallas, TX, and by grant HL54322 from the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.; the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH)","institution_ids":[]},{"raw_affiliation_string":"and the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH); Supported, in part, by a Grant-in-Aid to M. H. Weil by the American Heart Association, Dallas, TX, and by grant HL54322 from the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.; the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054666288","display_name":"Jinglan Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jinglan Wang","raw_affiliation_strings":["From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH)","and the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)","From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH); Supported, in part, by a Grant-in-Aid to M. H. Weil by the American Heart Association, Dallas, TX, and by grant HL54322 from the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.; the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH)","institution_ids":[]},{"raw_affiliation_string":"and the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH); Supported, in part, by a Grant-in-Aid to M. H. Weil by the American Heart Association, Dallas, TX, and by grant HL54322 from the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.; the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101738619","display_name":"Lei Huang","orcid":"https://orcid.org/0000-0003-4400-4751","observed_orcids":["https://orcid.org/0000-0003-4400-4751"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lei Huang","raw_affiliation_strings":["From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH)","and the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)","From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH); Supported, in part, by a Grant-in-Aid to M. H. Weil by the American Heart Association, Dallas, TX, and by grant HL54322 from the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.; the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH)","institution_ids":[]},{"raw_affiliation_string":"and the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"From the Institute of Critical Care Medicine, Palm Springs, CA (GC, MHW, SS, WT, JW, LH); Supported, in part, by a Grant-in-Aid to M. H. Weil by the American Heart Association, Dallas, TX, and by grant HL54322 from the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.; the Keck School of Medicine of the University of Southern California, Los Angeles, CA (MHW, SS, WT)","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":7.1943,"has_fulltext":false,"cited_by_count":61,"citation_normalized_percentile":{"value":0.97009911,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"32","issue":"Supplement","first_page":"S440","last_page":"S443"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10645","display_name":"Cardiac Arrest and Resuscitation","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10645","display_name":"Cardiac Arrest and Resuscitation","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/esmolol","display_name":"esmolol","score":0.8759999871253967},{"id":"https://openalex.org/keywords/beta1-adrenergic-blockade","display_name":"beta1-adrenergic blockade","score":0.9559999704360962},{"id":"https://openalex.org/keywords/cardiopulmonary-resuscitation","display_name":"cardiopulmonary resuscitation","score":0.9980000257492065},{"id":"https://openalex.org/keywords/ventricular-fibrillation","display_name":"ventricular fibrillation","score":0.9919999837875366},{"id":"https://openalex.org/keywords/post-resuscitation-myocardial-dysfunction","display_name":"post-resuscitation myocardial dysfunction","score":0.7879999876022339},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.5809999704360962},{"id":"https://openalex.org/keywords/defibrillation","display_name":"defibrillation","score":0.8949999809265137},{"id":"https://openalex.org/keywords/left-ventricular-diastolic-function","display_name":"left ventricular diastolic function","score":0.781000018119812},{"id":"https://openalex.org/keywords/myocardial-contractility","display_name":"cardiac contractility","score":0.5879999995231628}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.958585798740387},{"id":"https://openalex.org/C2777055891","wikidata":"https://www.wikidata.org/wiki/Q185325","display_name":"Cardiopulmonary resuscitation","level":3,"score":0.8500027656555176},{"id":"https://openalex.org/C2778468042","wikidata":"https://www.wikidata.org/wiki/Q273976","display_name":"Blockade","level":3,"score":0.6880215406417847},{"id":"https://openalex.org/C2778165595","wikidata":"https://www.wikidata.org/wiki/Q5491454","display_name":"Resuscitation","level":2,"score":0.5322933793067932},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.49883604049682617},{"id":"https://openalex.org/C158453852","wikidata":"https://www.wikidata.org/wiki/Q4684738","display_name":"Adrenergic","level":3,"score":0.48679444193840027},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.33711957931518555},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3212360143661499},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.04749014973640442}],"mesh":[{"descriptor_ui":"D000319","descriptor_name":"Adrenergic beta-Antagonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011412","descriptor_name":"Propanolamines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D014693","descriptor_name":"Ventricular Fibrillation","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D016887","descriptor_name":"Cardiopulmonary Resuscitation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/01.ccm.0000134263.32657.34","doi":"https://doi.org/10.1097/01.ccm.0000134263.32657.34","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.ccm.0000134263.32657.34","pdf_url":null,"source":{"id":"https://openalex.org/S108732581","display_name":"Critical Care Medicine","issn_l":"0090-3493","issn":["0090-3493","1530-0293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Care Medicine","raw_type":"journal-article"},{"id":"pmid:15508675","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15508675","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical care medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4610409417","display_name":"ADRENERGIC AGENTS FOR CARDIOPULMONARY RESUSCITATION","funder_award_id":"R01HL054322","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W89387317","https://openalex.org/W305479844","https://openalex.org/W1913514340","https://openalex.org/W1985078950","https://openalex.org/W2008302570","https://openalex.org/W2010293252","https://openalex.org/W2014165898","https://openalex.org/W2015238475","https://openalex.org/W2028106043","https://openalex.org/W2046785549","https://openalex.org/W2047512244","https://openalex.org/W2063662218","https://openalex.org/W2072064992","https://openalex.org/W2113519449","https://openalex.org/W2152966419","https://openalex.org/W2155987968","https://openalex.org/W2169792680"],"related_works":["https://openalex.org/W2414528801","https://openalex.org/W2142894941","https://openalex.org/W2098091435","https://openalex.org/W2992774290","https://openalex.org/W3028972301","https://openalex.org/W2016450693","https://openalex.org/W2377614927","https://openalex.org/W2108435498","https://openalex.org/W1963838778","https://openalex.org/W3138435965"],"abstract_inverted_index":{"OBJECTIVE:":[0],"The":[1],"short-acting":[2,156],"beta1-selective":[3,157],"adrenergic":[4,158],"blocking":[5,159],"agent,":[6,160],"esmolol,":[7],"was":[8,41,93,151],"administrated":[9],"during":[10,88,163],"cardiopulmonary":[11,89,164],"resuscitation":[12,18,58],"with":[13,59],"the":[14,119,177],"hypothesis":[15],"that":[16],"initial":[17,168],"and":[19,64,133,147,175],"postresuscitation":[20,172,180],"survival":[21,150],"would":[22],"be":[23],"improved.":[24],"DESIGN:":[25],"Prospective,":[26],"randomized,":[27],"controlled":[28],"study.":[29],"SETTING:":[30],"Animal":[31],"research":[32],"laboratory.":[33],"SUBJECTS:":[34],"Male":[35],"Sprague-Dawley":[36,46],"rats.":[37],"INTERVENTIONS:":[38],"Ventricular":[39],"fibrillation":[40],"induced":[42],"in":[43,75],"18":[44],"male":[45],"rats,":[47],"which":[48],"were":[49,68,128,141],"then":[50],"left":[51,134],"untreated":[52],"for":[53],"6":[54],"mins":[55,97],"before":[56,115],"attempted":[57,94],"precordial":[60],"compression,":[61],"mechanical":[62],"ventilation,":[63],"electrical":[65,113],"defibrillation.":[66],"Animals":[67],"randomized":[69],"to":[70],"receive":[71],"300":[72],"microg/kg":[73],"esmolol":[74,145],"a":[76,108],"volume":[77,84],"of":[78,85,98,112,118,124,138,149,179],"200":[79],"microL":[80],"or":[81],"an":[82],"equivalent":[83],"saline":[86],"placebo":[87],"resuscitation.":[90,116],"Electrical":[91],"defibrillation":[92],"after":[95,144],"12":[96],"ventricular":[99,135],"fibrillation.":[100],"MEASUREMENTS":[101],"AND":[102],"MAIN":[103],"RESULTS:":[104],"Esmolol-treated":[105],"animals":[106,127,140],"required":[107],"significantly":[109,142,152,166],"smaller":[110],"number":[111],"shocks":[114],"Each":[117],"esmolol-treated":[120],"but":[121],"only":[122],"five":[123],"nine":[125],"placebo-treated":[126],"successfully":[129],"resuscitated.":[130],"Postresuscitation":[131],"contractile":[132],"diastolic":[136],"functions":[137],"resuscitated":[139],"better":[143],"administration":[146],"duration":[148,178],"increased.":[153],"CONCLUSIONS:":[154],"A":[155],"when":[161],"administered":[162],"resuscitation,":[165,170],"improved":[167],"cardiac":[169],"minimized":[171],"myocardial":[173],"dysfunction,":[174],"increased":[176],"survival.":[181]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}