{"id":"https://openalex.org/W2043198570","doi":"https://doi.org/10.1046/j.1365-2222.2003.01659.x","title":"Neonatal interleukin\u201012 capacity is associated with variations in allergen\u2010specific immune responses in the neonatal and postnatal periods","display_name":"Neonatal interleukin\u201012 capacity is associated with variations in allergen\u2010specific immune responses in the neonatal and postnatal periods","publication_year":2003,"publication_date":"2003-05-01","ids":{"openalex":"https://openalex.org/W2043198570","doi":"https://doi.org/10.1046/j.1365-2222.2003.01659.x","mag":"2043198570","pmid":"https://pubmed.ncbi.nlm.nih.gov/12752583"},"language":"en","primary_location":{"id":"doi:10.1046/j.1365-2222.2003.01659.x","doi":"https://doi.org/10.1046/j.1365-2222.2003.01659.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1365-2222.2003.01659.x","pdf_url":null,"source":{"id":"https://openalex.org/S17239246","display_name":"Clinical & Experimental Allergy","issn_l":"0954-7894","issn":["0954-7894","1365-2222"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical &amp; Experimental Allergy","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077492180","display_name":"Susan L. Prescott","orcid":"https://orcid.org/0000-0003-4845-8590","observed_orcids":["https://orcid.org/0000-0003-4845-8590"]},"institutions":[{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]},{"id":"https://openalex.org/I2800419323","display_name":"Princess Margaret Hospital for Children","ror":"https://ror.org/04ec98z42","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2799506148","https://openalex.org/I2800419323","https://openalex.org/I2800882159","https://openalex.org/I4387155440"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"S. L. Prescott","raw_affiliation_strings":["Department of Paediatrics, Division of Clinical Sciences and Division of Cell Biology, School of Paediatrics and Child Health Research, University of Western Australia, and Princess Margaret Hospital, Perth, Australia. susanp@ichr.uwa.edu.au","Department of Paediatrics,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatrics, Division of Clinical Sciences and Division of Cell Biology, School of Paediatrics and Child Health Research, University of Western Australia, and Princess Margaret Hospital, Perth, Australia. susanp@ichr.uwa.edu.au","institution_ids":["https://openalex.org/I177877127","https://openalex.org/I2800419323"]},{"raw_affiliation_string":"Department of Paediatrics,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006983384","display_name":"Angie L. Taylor","orcid":"https://orcid.org/0009-0008-9136-7444","observed_orcids":["https://orcid.org/0009-0008-9136-7444"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. Taylor","raw_affiliation_strings":["Department of Paediatrics,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatrics,","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"B. King","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B. King","raw_affiliation_strings":["Division of Clinical Sciences and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Clinical Sciences and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000586422","display_name":"Janet A. Dunstan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Dunstan","raw_affiliation_strings":["Department of Paediatrics,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatrics,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035806248","display_name":"John W. Upham","orcid":"https://orcid.org/0000-0002-0017-3433","observed_orcids":["https://orcid.org/0000-0002-0017-3433"]},"institutions":[{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]},{"id":"https://openalex.org/I2800419323","display_name":"Princess Margaret Hospital for Children","ror":"https://ror.org/04ec98z42","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2799506148","https://openalex.org/I2800419323","https://openalex.org/I2800882159","https://openalex.org/I4387155440"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"J. W. Upham","raw_affiliation_strings":["Division of Cell Biology, School of Paediatrics and Child Health Research, University of Western Australia, and Princess Margaret Hospital, Perth, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cell Biology, School of Paediatrics and Child Health Research, University of Western Australia, and Princess Margaret Hospital, Perth, Australia","institution_ids":["https://openalex.org/I177877127","https://openalex.org/I2800419323"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057332050","display_name":"Catherine A. Thornton","orcid":"https://orcid.org/0000-0002-5153-573X","observed_orcids":["https://orcid.org/0000-0002-5153-573X"]},"institutions":[{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]},{"id":"https://openalex.org/I2800419323","display_name":"Princess Margaret Hospital for Children","ror":"https://ror.org/04ec98z42","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2799506148","https://openalex.org/I2800419323","https://openalex.org/I2800882159","https://openalex.org/I4387155440"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"C. A. Thornton","raw_affiliation_strings":["Department of Paediatrics,","Division of Cell Biology, School of Paediatrics and Child Health Research, University of Western Australia, and Princess Margaret Hospital, Perth, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatrics,","institution_ids":[]},{"raw_affiliation_string":"Division of Cell Biology, School of Paediatrics and Child Health Research, University of Western Australia, and Princess Margaret Hospital, Perth, Australia","institution_ids":["https://openalex.org/I177877127","https://openalex.org/I2800419323"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017272011","display_name":"Patrick G. Holt","orcid":"https://orcid.org/0000-0003-1193-0935","observed_orcids":["https://orcid.org/0000-0003-1193-0935"]},"institutions":[{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]},{"id":"https://openalex.org/I2800419323","display_name":"Princess Margaret Hospital for Children","ror":"https://ror.org/04ec98z42","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2799506148","https://openalex.org/I2800419323","https://openalex.org/I2800882159","https://openalex.org/I4387155440"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"P. G. Holt","raw_affiliation_strings":["Division of Cell Biology, School of Paediatrics and Child Health Research, University of Western Australia, and Princess Margaret Hospital, Perth, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cell Biology, School of Paediatrics and Child Health Research, University of Western Australia, and Princess Margaret Hospital, Perth, Australia","institution_ids":["https://openalex.org/I177877127","https://openalex.org/I2800419323"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5077492180"],"corresponding_institution_ids":["https://openalex.org/I177877127","https://openalex.org/I2800419323"],"apc_list":{"value":4760,"currency":"USD","value_usd":4760},"apc_paid":null,"fwci":6.7003,"has_fulltext":false,"cited_by_count":84,"citation_normalized_percentile":{"value":0.97155538,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"33","issue":"5","first_page":"566","last_page":"572"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.8148999810218811,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.8148999810218811,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.11150000244379044,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.048700001090765,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/il-12","display_name":"IL-12","score":0.8840000033378601},{"id":"https://openalex.org/keywords/neonatal-immune-development","display_name":"neonatal immune development","score":0.8140000104904175},{"id":"https://openalex.org/keywords/allergen-specific-immune-response","display_name":"allergen-specific immune response","score":0.8100000023841858},{"id":"https://openalex.org/keywords/th1-th2-balance","display_name":"Th1/Th2 balance","score":0.7990000247955322},{"id":"https://openalex.org/keywords/house-dust-mites","display_name":"house dust mites","score":0.6880000233650208},{"id":"https://openalex.org/keywords/ovalbumin","display_name":"ovalbumin","score":0.9929999709129333},{"id":"https://openalex.org/keywords/beta-lactoglobulin","display_name":"\u03b2-lactoglobulin","score":0.8899999856948853},{"id":"https://openalex.org/keywords/il-13","display_name":"IL-13","score":0.972000002861023},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.7620000243186951},{"id":"https://openalex.org/keywords/atopic-sensitization","display_name":"atopic sensitization","score":0.5920000076293945},{"id":"https://openalex.org/keywords/allergic-diseases","display_name":"allergic diseases","score":0.5230000019073486},{"id":"https://openalex.org/keywords/asthma","display_name":"asthma","score":0.5239999890327454},{"id":"https://openalex.org/keywords/atopic-dermatitis","display_name":"atopic dermatitis","score":0.9760000109672546}],"concepts":[{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.8040106892585754},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.6709306836128235},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.655245304107666},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6365678310394287},{"id":"https://openalex.org/C2778166374","wikidata":"https://www.wikidata.org/wiki/Q29938","display_name":"House dust mite","level":4,"score":0.6128702759742737},{"id":"https://openalex.org/C137061746","wikidata":"https://www.wikidata.org/wiki/Q736033","display_name":"Peripheral blood mononuclear cell","level":3,"score":0.5432125926017761},{"id":"https://openalex.org/C2776946954","wikidata":"https://www.wikidata.org/wiki/Q420291","display_name":"Ovalbumin","level":3,"score":0.5306944847106934},{"id":"https://openalex.org/C2780510475","wikidata":"https://www.wikidata.org/wiki/Q186752","display_name":"Allergen","level":3,"score":0.5013120174407959},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.47071903944015503},{"id":"https://openalex.org/C2777697326","wikidata":"https://www.wikidata.org/wiki/Q757678","display_name":"Atopy","level":3,"score":0.4683268368244171},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.43024155497550964},{"id":"https://openalex.org/C2776027960","wikidata":"https://www.wikidata.org/wiki/Q769815","display_name":"Food allergy","level":3,"score":0.4100399911403656},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.18885591626167297},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.1268327832221985},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000485","descriptor_name":"Allergens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000938","descriptor_name":"Antigen-Presenting Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D005312","descriptor_name":"Fetal Blood","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006967","descriptor_name":"Hypersensitivity","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006967","descriptor_name":"Hypersensitivity","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008070","descriptor_name":"Lipopolysaccharides","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008213","descriptor_name":"Lymphocyte Activation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008934","descriptor_name":"Mitogens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D018664","descriptor_name":"Interleukin-12","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1046/j.1365-2222.2003.01659.x","doi":"https://doi.org/10.1046/j.1365-2222.2003.01659.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1365-2222.2003.01659.x","pdf_url":null,"source":{"id":"https://openalex.org/S17239246","display_name":"Clinical & Experimental Allergy","issn_l":"0954-7894","issn":["0954-7894","1365-2222"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical &amp; Experimental Allergy","raw_type":"journal-article"},{"id":"pmid:12752583","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12752583","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:publications/043de0e8-42fe-423e-8e3a-055c2da03d79","doi":null,"is_oa":false,"landing_page_url":"https://admin.research-repository.uwa.edu.au/en/publications/043de0e8-42fe-423e-8e3a-055c2da03d79","pdf_url":null,"source":{"id":"https://openalex.org/S4306402492","display_name":"UWA Profiles and Research Repository (UWA)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177877127","host_organization_name":"The University of Western Australia","host_organization_lineage":["https://openalex.org/I177877127"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Prescott, S, Taylor, A, King, B, Dunstan, J A, Upham, J, Thornton, C A & Holt, P 2003, 'Neonatal interleukin-12 capacity is associated with variations in allergen-specific immune responses in the neonatal and postnatal response periods', Clinical and Experimental Allergy, vol. 33, no. 5, pp. 566-572. https://doi.org/10.1046/j.1365-2222.2003.01659.x","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1487602178","https://openalex.org/W1562008267","https://openalex.org/W1760518423","https://openalex.org/W1978116307","https://openalex.org/W1983895762","https://openalex.org/W1985975290","https://openalex.org/W1992245040","https://openalex.org/W1994486558","https://openalex.org/W2012749291","https://openalex.org/W2017684091","https://openalex.org/W2028353803","https://openalex.org/W2038274545","https://openalex.org/W2053481392","https://openalex.org/W2054517109","https://openalex.org/W2059040619","https://openalex.org/W2059378560","https://openalex.org/W2071415293","https://openalex.org/W2085219761","https://openalex.org/W2124133622","https://openalex.org/W2158500407","https://openalex.org/W4232990985","https://openalex.org/W4237439965","https://openalex.org/W4245528966","https://openalex.org/W4291192970","https://openalex.org/W4300696144"],"related_works":["https://openalex.org/W2128224497","https://openalex.org/W1973317602","https://openalex.org/W2059378560","https://openalex.org/W4313387765","https://openalex.org/W2073662113","https://openalex.org/W2017298157","https://openalex.org/W2057911513","https://openalex.org/W1994486558","https://openalex.org/W2155701857","https://openalex.org/W2003972470"],"abstract_inverted_index":{"BACKGROUND":[0],"AND":[1],"OBJECTIVES:":[2],"A":[3],"reduced":[4,380],"capacity":[5,49,81,325],"of":[6,33,73,82,104,195,305,310],"antigen":[7],"presenting":[8],"cells":[9,23,189],"(APC)":[10],"to":[11,21,67,88,94,112,160,263,297,340,393,413],"provide":[12],"pro-T":[13],"helper":[14,35],"1":[15],"(Th1)":[16],"signals,":[17],"such":[18],"as":[19,173],"IL-12,":[20],"T":[22,34,64,381],"during":[24],"early":[25,409],"life":[26,410],"may":[27,411],"be":[28,341],"implicated":[29],"in":[30,53,62,92,101,148,326,343,363,373,395,405,408],"the":[31,45,48,54,70,149,327,344,356,361,374,396,401],"development":[32,72],"2":[36,311],"(Th2)-mediated":[37],"allergic":[38,74],"disease.":[39],"In":[40],"this":[41,364],"study":[42],"we":[43],"examined":[44],"relationships":[46],"between":[47,320],"for":[50,226,336],"IL-12":[51,90,118,154,196,204,217,288,324,338,371],"responses":[52,66,111,119,141,155,205,218,262,289,296,339,392,417],"neonatal":[55,84,150,198,216,223,260,285,328,337,386],"period":[56,376],"and":[57,69,114,133,136,138,145,151,163,171,248,275,286,302,323,389],"atopic":[58,115,161,164,321],"risk":[59,162,322,358],"(family":[60],"allergy),":[61],"vitro":[63],"cell":[65,382],"allergens,":[68],"subsequent":[71],"disease":[75],"at":[76,179,299,351],"6":[77,180,352],"years.":[78],"METHODS:":[79],"The":[80,117],"circulating":[83],"(and":[85,96],"maternal)":[86],"APC":[87,370,406],"produce":[89],"p70":[91],"response":[93],"LPS":[95],"IFN-gamma)":[97],"stimulation":[98],"was":[99,317,332,366,377],"assessed":[100],"a":[102,333],"group":[103],"60":[105],"children":[106,346],"with":[107,122,222,259,293,355,379,419],"previously":[108],"well-characterized":[109],"immune":[110],"allergens":[113,265],"outcomes.":[116],"were":[120,156,206,219,290,313],"compared":[121,158],"allergen-induced":[123],"lymphoproliferation":[124],"(to":[125,142],"house":[126],"dust":[127],"mite":[128],"(HDM)":[129],"ovalbumin":[130],"(OVA),":[131],"cat":[132,241],"beta-lactoglobulin":[134],"(BLG))":[135],"IL-13":[137,261],"IFN-gamma":[139,295],"cytokine":[140,416],"OVA,":[143],"HDM":[144,227,298],"phytohaemaglutinin":[146],"(PHA))":[147],"postnatal":[152,294,397],"periods.":[153],"also":[157],"according":[159],"outcomes":[165],"(doctor-diagnosed":[166],"asthma,":[167],"eczema,":[168],"food":[169],"allergies":[170],"sensitization":[172],"evidenced":[174],"by":[175],"skin":[176],"prick":[177],"testing)":[178],"years":[181,312,353],"clinical":[182,349],"follow-up.":[183],"RESULTS:":[184],"Maternal":[185],"peripheral":[186],"blood":[187],"mononuclear":[188],"(PBMC)":[190],"synthesized":[191],"significantly":[192,207],"greater":[193],"amounts":[194],"than":[197],"PBMC,":[199],"though":[200],"within":[201],"maternal-infant":[202],"pairs":[203],"correlated":[208,221,258,292],"(r":[209,228,235,242,250],"=":[210,213,229,236,243,246,251,254,269,273,278,282],"0.4,":[211,271],"P":[212,231,238,245,253,272,281],"0.019).":[214],"Moreover,":[215],"positively":[220,291],"allergen":[224,394],"proliferation":[225],"0.6,":[230],"<":[232,239],"0.0001),":[233,240],"OVA":[234],"0.55,":[237,252],"0.5,":[244,280],"0.003)":[247],"BLG":[249],"0.001),":[255],"but":[256,330],"negatively":[257],"both":[264],"tested":[266],"(HDM:":[267],"r":[268,277],"-":[270,279],"0.03":[274],"OVA:":[276],"0.001).":[283],"Both":[284],"maternal":[287],"12,":[300],"18":[301],"24":[303],"months":[304],"age":[306,309],"(responses":[307],"after":[308],"not":[314],"assessed).":[315],"There":[316],"no":[318],"relationship":[319],"period,":[329],"there":[331],"(non-significant)":[334],"trend":[335],"lower":[342],"high-risk":[345],"who":[347],"developed":[348],"allergy":[350],"(compared":[354],"low":[357],"group)":[359],"although":[360],"number":[362],"analysis":[365],"small.":[367],"CONCLUSIONS:":[368],"Reduced":[369],"production":[372],"perinatal":[375],"associated":[378,418],"activation":[383],"(lymphoproliferation),":[384],"stronger":[385],"Th2":[387],"responses,":[388],"weaker":[390],"Th1":[391],"period.":[398],"This":[399],"supports":[400],"notion":[402],"that":[403],"variations":[404],"function":[407],"contribute":[412],"altered":[414],"allergen-specific":[415],"later":[420],"allergy.":[421]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}