{"id":"https://openalex.org/W2043129641","doi":"https://doi.org/10.1016/j.jmb.2012.06.041","title":"Alpha-1 Giardin is an Annexin with Highly Unusual Calcium-Regulated Mechanisms","display_name":"Alpha-1 Giardin is an Annexin with Highly Unusual Calcium-Regulated Mechanisms","publication_year":2012,"publication_date":"2012-07-10","ids":{"openalex":"https://openalex.org/W2043129641","doi":"https://doi.org/10.1016/j.jmb.2012.06.041","mag":"2043129641","pmid":"https://pubmed.ncbi.nlm.nih.gov/22796298"},"language":"en","primary_location":{"id":"doi:10.1016/j.jmb.2012.06.041","doi":"https://doi.org/10.1016/j.jmb.2012.06.041","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jmb.2012.06.041","pdf_url":"https://ars.els-cdn.com/content/image/1-s2.0-S0022283612005530-fx1_lrg.jpg","source":{"id":"https://openalex.org/S46058472","display_name":"Journal of Molecular Biology","issn_l":"0022-2836","issn":["0022-2836","1089-8638"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://ars.els-cdn.com/content/image/1-s2.0-S0022283612005530-fx1_lrg.jpg","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078793972","display_name":"Saroja K. Weeratunga","orcid":"https://orcid.org/0009-0009-8417-7420","observed_orcids":["https://orcid.org/0009-0009-8417-7420","https://orcid.org/0000-0002-4756-911X"]},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Saroja K. Weeratunga","raw_affiliation_strings":["Structural Chemistry Program, Eskitis Institute for Cell and Molecular Therapies, Griffith University, Brisbane, Qld 4111, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Structural Chemistry Program, Eskitis Institute for Cell and Molecular Therapies, Griffith University, Brisbane, Qld 4111, Australia","institution_ids":["https://openalex.org/I11701301"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007376243","display_name":"Asiah Osman","orcid":"https://orcid.org/0000-0001-7616-8414","observed_orcids":["https://orcid.org/0000-0001-7616-8414"]},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Asiah Osman","raw_affiliation_strings":["Structural Chemistry Program, Eskitis Institute for Cell and Molecular Therapies, Griffith University, Brisbane, Qld 4111, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Structural Chemistry Program, Eskitis Institute for Cell and Molecular Therapies, Griffith University, Brisbane, Qld 4111, Australia","institution_ids":["https://openalex.org/I11701301"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077993367","display_name":"Nien\u2010Jen Hu","orcid":"https://orcid.org/0000-0002-0917-0677","observed_orcids":["https://orcid.org/0000-0002-0917-0677"]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nien-Jen Hu","raw_affiliation_strings":["Division of Molecular Biosciences, Imperial College London, London, SW7 2AZ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Molecular Biosciences, Imperial College London, London, SW7 2AZ, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063128380","display_name":"Conan K. L. Wang","orcid":"https://orcid.org/0000-0002-7973-7632","observed_orcids":["https://orcid.org/0000-0002-7973-7632"]},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Conan K. Wang","raw_affiliation_strings":["Structural Chemistry Program, Eskitis Institute for Cell and Molecular Therapies, Griffith University, Brisbane, Qld 4111, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Structural Chemistry Program, Eskitis Institute for Cell and Molecular Therapies, Griffith University, Brisbane, Qld 4111, Australia","institution_ids":["https://openalex.org/I11701301"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111610774","display_name":"Lyndel Mason","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Lyndel Mason","raw_affiliation_strings":["Structural Chemistry Program, Eskitis Institute for Cell and Molecular Therapies, Griffith University, Brisbane, Qld 4111, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Structural Chemistry Program, Eskitis Institute for Cell and Molecular Therapies, Griffith University, Brisbane, Qld 4111, Australia","institution_ids":["https://openalex.org/I11701301"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057764480","display_name":"Staffan G. Sv\u00e4rd","orcid":"https://orcid.org/0000-0002-7392-1746","observed_orcids":["https://orcid.org/0000-0002-7392-1746"]},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Staffan Sv\u00e4rd","raw_affiliation_strings":["Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016788794","display_name":"Gregory A. Hope","orcid":"https://orcid.org/0000-0003-2694-3456","observed_orcids":["https://orcid.org/0000-0003-2694-3456"]},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Greg Hope","raw_affiliation_strings":["School of Biomolecular and Physical Sciences, Griffith University, Brisbane, Qld 4111, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biomolecular and Physical Sciences, Griffith University, Brisbane, Qld 4111, Australia","institution_ids":["https://openalex.org/I11701301"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039640617","display_name":"Malcolm K. Jones","orcid":"https://orcid.org/0000-0002-0035-6141","observed_orcids":["https://orcid.org/0000-0002-0035-6141"]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]},{"id":"https://openalex.org/I217937681","display_name":"QIMR Berghofer Medical Research Institute","ror":"https://ror.org/004y8wk30","country_code":"AU","type":"facility","lineage":["https://openalex.org/I217937681"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Malcolm K. Jones","raw_affiliation_strings":["Queensland Institute of Medical Research, Brisbane, Queensland 4029, Australia","School of Veterinary Sciences, The University of Queensland, Gatton, Qld 4343, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Queensland Institute of Medical Research, Brisbane, Queensland 4029, Australia","institution_ids":["https://openalex.org/I217937681"]},{"raw_affiliation_string":"School of Veterinary Sciences, The University of Queensland, Gatton, Qld 4343, Australia","institution_ids":["https://openalex.org/I165143802"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025007734","display_name":"Andreas Hofmann","orcid":"https://orcid.org/0000-0003-4408-5467","observed_orcids":["https://orcid.org/0000-0003-4408-5467","https://orcid.org/0000-0002-2014-6547","https://orcid.org/0000-0002-9102-7641","https://orcid.org/0000-0002-4800-8429","https://orcid.org/0000-0001-5450-6267"]},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I86467917","display_name":"James Cook University","ror":"https://ror.org/04gsp2c11","country_code":"AU","type":"education","lineage":["https://openalex.org/I86467917"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Andreas Hofmann","raw_affiliation_strings":["Faculty of Veterinary Science, The University of Melbourne, Parkville, Victoria 3010, Australia","Queensland Tropical Health Alliance, James Cook University Douglas Campus, Townsville, Qld 4811, Australia","Structural Chemistry Program, Eskitis Institute for Cell and Molecular Therapies, Griffith University, Brisbane, Qld 4111, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Veterinary Science, The University of Melbourne, Parkville, Victoria 3010, Australia","institution_ids":["https://openalex.org/I165779595"]},{"raw_affiliation_string":"Queensland Tropical Health Alliance, James Cook University Douglas Campus, Townsville, Qld 4811, Australia","institution_ids":["https://openalex.org/I86467917"]},{"raw_affiliation_string":"Structural Chemistry Program, Eskitis Institute for Cell and Molecular Therapies, Griffith University, Brisbane, Qld 4111, Australia","institution_ids":["https://openalex.org/I11701301"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5025007734"],"corresponding_institution_ids":["https://openalex.org/I11701301","https://openalex.org/I165779595","https://openalex.org/I86467917"],"apc_list":{"value":4730,"currency":"USD","value_usd":4730},"apc_paid":null,"fwci":0.5249,"has_fulltext":true,"cited_by_count":25,"citation_normalized_percentile":{"value":0.59055587,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"423","issue":"2","first_page":"169","last_page":"181"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12030","display_name":"S100 Proteins and Annexins","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12030","display_name":"S100 Proteins and Annexins","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11086","display_name":"Parasitic Infections and Diagnostics","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/giardia","display_name":"Giardia","score":0.6690000295639038},{"id":"https://openalex.org/keywords/annexins","display_name":"annexins","score":0.7730000019073486},{"id":"https://openalex.org/keywords/calcium-binding","display_name":"calcium binding","score":0.7200000286102295},{"id":"https://openalex.org/keywords/crystal-structure","display_name":"crystal structure","score":0.753000020980835},{"id":"https://openalex.org/keywords/membrane-binding","display_name":"membrane binding","score":0.375},{"id":"https://openalex.org/keywords/protein-dimerization","display_name":"protein dimerization","score":0.8360000252723694},{"id":"https://openalex.org/keywords/excystation","display_name":"excystation","score":0.9139999747276306},{"id":"https://openalex.org/keywords/trophozoites","display_name":"trophozoites","score":0.8420000076293945},{"id":"https://openalex.org/keywords/cysts","display_name":"cysts","score":0.4309999942779541},{"id":"https://openalex.org/keywords/vaccine-targets","display_name":"vaccine targets","score":0.7559999823570251}],"concepts":[{"id":"https://openalex.org/C88634738","wikidata":"https://www.wikidata.org/wiki/Q24769543","display_name":"Annexin","level":3,"score":0.7086790204048157},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.6836925745010376},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5804505348205566},{"id":"https://openalex.org/C30345302","wikidata":"https://www.wikidata.org/wiki/Q14908233","display_name":"Annexin A2","level":4,"score":0.523953914642334},{"id":"https://openalex.org/C142669718","wikidata":"https://www.wikidata.org/wiki/Q154626","display_name":"Cytoskeleton","level":3,"score":0.4226284325122833},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.40793120861053467},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3761042654514313},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2864568829536438},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.14678552746772766},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D003598","descriptor_name":"Cytoskeletal Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003598","descriptor_name":"Cytoskeletal Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006025","descriptor_name":"Glycosaminoglycans","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006025","descriptor_name":"Glycosaminoglycans","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008567","descriptor_name":"Membranes, Artificial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010743","descriptor_name":"Phospholipids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D016829","descriptor_name":"Giardia lamblia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016829","descriptor_name":"Giardia lamblia","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.jmb.2012.06.041","doi":"https://doi.org/10.1016/j.jmb.2012.06.041","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jmb.2012.06.041","pdf_url":"https://ars.els-cdn.com/content/image/1-s2.0-S0022283612005530-fx1_lrg.jpg","source":{"id":"https://openalex.org/S46058472","display_name":"Journal of Molecular Biology","issn_l":"0022-2836","issn":["0022-2836","1089-8638"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular Biology","raw_type":"journal-article"},{"id":"pmid:22796298","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22796298","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of molecular biology","raw_type":"Journal Article"},{"id":"pmh:oai:research-repository.griffith.edu.au:10072/47617","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10072/47617","pdf_url":"http://hdl.handle.net/10072/47617","source":{"id":"https://openalex.org/S7407064376","display_name":"Griffith Research Online","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal article"},{"id":"pmh:oai:research-repository.griffith.edu.au:10072/54041","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10072/54041","pdf_url":null,"source":{"id":"https://openalex.org/S7407064376","display_name":"Griffith Research Online","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Conference output"}],"best_oa_location":{"id":"doi:10.1016/j.jmb.2012.06.041","doi":"https://doi.org/10.1016/j.jmb.2012.06.041","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jmb.2012.06.041","pdf_url":"https://ars.els-cdn.com/content/image/1-s2.0-S0022283612005530-fx1_lrg.jpg","source":{"id":"https://openalex.org/S46058472","display_name":"Journal of Molecular Biology","issn_l":"0022-2836","issn":["0022-2836","1089-8638"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320314616","display_name":"James N. Kirby Foundation","ror":"https://ror.org/0367ekx87"},{"id":"https://openalex.org/F4320320540","display_name":"Australian Synchrotron","ror":"https://ror.org/03vk18a84"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320334705","display_name":"National Health and Medical Research Council","ror":"https://ror.org/011kf5r70"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2043129641.pdf","grobid_xml":"https://content.openalex.org/works/W2043129641.grobid-xml"},"referenced_works_count":51,"referenced_works":["https://openalex.org/W31196662","https://openalex.org/W255996521","https://openalex.org/W1946135624","https://openalex.org/W1968307525","https://openalex.org/W1970526067","https://openalex.org/W1972589331","https://openalex.org/W1975015319","https://openalex.org/W1978034047","https://openalex.org/W1978570354","https://openalex.org/W1983732912","https://openalex.org/W1986191025","https://openalex.org/W1992191979","https://openalex.org/W1992479332","https://openalex.org/W1994301557","https://openalex.org/W1996607909","https://openalex.org/W2001641653","https://openalex.org/W2008017834","https://openalex.org/W2009470785","https://openalex.org/W2013083986","https://openalex.org/W2016770107","https://openalex.org/W2017469968","https://openalex.org/W2021372863","https://openalex.org/W2021869123","https://openalex.org/W2032899389","https://openalex.org/W2045481255","https://openalex.org/W2046661698","https://openalex.org/W2048527318","https://openalex.org/W2056734463","https://openalex.org/W2073178782","https://openalex.org/W2074349548","https://openalex.org/W2080852273","https://openalex.org/W2084039289","https://openalex.org/W2090179718","https://openalex.org/W2091928538","https://openalex.org/W2092796622","https://openalex.org/W2093451052","https://openalex.org/W2100641899","https://openalex.org/W2102335249","https://openalex.org/W2104107694","https://openalex.org/W2104371389","https://openalex.org/W2106246537","https://openalex.org/W2114622716","https://openalex.org/W2120644189","https://openalex.org/W2146654904","https://openalex.org/W2148557191","https://openalex.org/W2180229411","https://openalex.org/W2322586736","https://openalex.org/W2332348819","https://openalex.org/W2412963709","https://openalex.org/W2417570459","https://openalex.org/W2904473752"],"related_works":["https://openalex.org/W2080852273","https://openalex.org/W2046661698","https://openalex.org/W7119731512","https://openalex.org/W2016770107","https://openalex.org/W6964839213","https://openalex.org/W1994301557","https://openalex.org/W1970526067","https://openalex.org/W2076439035","https://openalex.org/W2546775262","https://openalex.org/W2117354234"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}