{"id":"https://openalex.org/W2042921673","doi":"https://doi.org/10.1016/j.clim.2006.04.070","title":"F.30. Abrogation of Established Inflammatory Arthritis By Honokiol: Gaba(a)-Mediated Alteration of CD40 and LMP1 Signaling in B-Cells","display_name":"F.30. Abrogation of Established Inflammatory Arthritis By Honokiol: Gaba(a)-Mediated Alteration of CD40 and LMP1 Signaling in B-Cells","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W2042921673","doi":"https://doi.org/10.1016/j.clim.2006.04.070","mag":"2042921673"},"language":"en","primary_location":{"id":"doi:10.1016/j.clim.2006.04.070","doi":"https://doi.org/10.1016/j.clim.2006.04.070","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.clim.2006.04.070","pdf_url":null,"source":{"id":"https://openalex.org/S37169408","display_name":"Clinical Immunology","issn_l":"1521-6616","issn":["1521-6616","1521-7035"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Immunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065514371","display_name":"Melissa E. Munroe","orcid":"https://orcid.org/0000-0002-6933-9745","observed_orcids":["https://orcid.org/0000-0002-6933-9745"]},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Melissa Munroe","raw_affiliation_strings":["Microbiology, Internal Medicine, and VAMC, University of Iowa, Iowa City, IA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology, Internal Medicine, and VAMC, University of Iowa, Iowa City, IA","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057604637","display_name":"Gail Abendroth Bishop","orcid":"https://orcid.org/0000-0002-1291-5078","observed_orcids":["https://orcid.org/0000-0002-1291-5078"]},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gail Bishop","raw_affiliation_strings":["Microbiology, Internal Medicine, and VAMC, University of Iowa, Iowa City, IA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology, Internal Medicine, and VAMC, University of Iowa, Iowa City, IA","institution_ids":["https://openalex.org/I126307644"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I126307644"],"apc_list":{"value":4400,"currency":"USD","value_usd":4400},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.26141145,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"119","issue":null,"first_page":"S61","last_page":"S61"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13026","display_name":"Natural Compounds in Disease Treatment","score":0.5946999788284302,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13026","display_name":"Natural Compounds in Disease Treatment","score":0.5946999788284302,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13677","display_name":"Magnolia and Illicium research","score":0.2930000126361847,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.04540000110864639,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/honokiol","display_name":"honokiol","score":0.9929999709129333},{"id":"https://openalex.org/keywords/inflammatory-arthritis","display_name":"inflammatory arthritis","score":0.9610000252723694},{"id":"https://openalex.org/keywords/gaba-a-receptor","display_name":"GABAA receptor","score":0.796999990940094},{"id":"https://openalex.org/keywords/cd40-signaling","display_name":"CD40 signaling","score":0.9399999976158142},{"id":"https://openalex.org/keywords/lmp1","display_name":"LMP1","score":0.7950000166893005},{"id":"https://openalex.org/keywords/b-cells","display_name":"B cells","score":0.7149999737739563},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.5699999928474426}],"concepts":[{"id":"https://openalex.org/C2781334404","wikidata":"https://www.wikidata.org/wiki/Q5896650","display_name":"Honokiol","level":2,"score":0.8555200099945068},{"id":"https://openalex.org/C2776821229","wikidata":"https://www.wikidata.org/wiki/Q16965166","display_name":"Inflammatory arthritis","level":3,"score":0.5731857419013977},{"id":"https://openalex.org/C2777077863","wikidata":"https://www.wikidata.org/wiki/Q170990","display_name":"Arthritis","level":2,"score":0.551964282989502},{"id":"https://openalex.org/C39347974","wikidata":"https://www.wikidata.org/wiki/Q21135811","display_name":"CD40","level":4,"score":0.5182220935821533},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.38489794731140137},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3794812560081482},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3682435154914856},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.35648560523986816},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3448602557182312},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.18054533004760742},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.17717167735099792},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09634643793106079},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.clim.2006.04.070","doi":"https://doi.org/10.1016/j.clim.2006.04.070","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.clim.2006.04.070","pdf_url":null,"source":{"id":"https://openalex.org/S37169408","display_name":"Clinical Immunology","issn_l":"1521-6616","issn":["1521-6616","1521-7035"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Immunology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1618362294","https://openalex.org/W195305865","https://openalex.org/W2431163764","https://openalex.org/W3141996291","https://openalex.org/W3141887943","https://openalex.org/W2017583004","https://openalex.org/W2391011940","https://openalex.org/W1996227600","https://openalex.org/W2010036320","https://openalex.org/W2073909066"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-01T08:54:57.152042","created_date":"2016-06-24T00:00:00"}