{"id":"https://openalex.org/W2042616366","doi":null,"title":"Renal failure secondary to massive infusion of vitamin C.","display_name":"Renal failure secondary to massive infusion of vitamin C.","publication_year":1984,"publication_date":"1984-10-05","ids":{"openalex":"https://openalex.org/W2042616366","mag":"2042616366","pmid":"https://pubmed.ncbi.nlm.nih.gov/6471294"},"language":"en","primary_location":{"id":"pmid:6471294","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6471294","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA","raw_type":"Case Reports"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111452943","display_name":"Charles J. McAllister","orcid":"https://orcid.org/0009-0000-3139-520X","observed_orcids":["https://orcid.org/0009-0000-3139-520X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C J McAllister","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056128409","display_name":"E. B. Scowden","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E B Scowden","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041206518","display_name":"F. Lawrence Dewberry","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F L Dewberry","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5112161040","display_name":"A Richman","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Richman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":38,"citation_normalized_percentile":{"value":0.14918712,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"252","issue":"13","first_page":"1684","last_page":"1684"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12554","display_name":"Vitamin C and Antioxidants Research","score":0.5175999999046326,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12554","display_name":"Vitamin C and Antioxidants Research","score":0.5175999999046326,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.17739999294281006,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10606","display_name":"Kidney Stones and Urolithiasis Treatments","score":0.11020000278949738,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vitamin-c-toxicity","display_name":"vitamin C toxicity","score":0.8180000185966492},{"id":"https://openalex.org/keywords/kidney-failure","display_name":"renal failure","score":0.7519999742507935},{"id":"https://openalex.org/keywords/oxalate-nephropathy","display_name":"oxalate nephropathy","score":0.9580000042915344},{"id":"https://openalex.org/keywords/chelation-therapy","display_name":"chelation therapy","score":0.7879999876022339},{"id":"https://openalex.org/keywords/anuria","display_name":"anuria","score":0.671999990940094},{"id":"https://openalex.org/keywords/hematuria","display_name":"hematuria","score":0.7910000085830688},{"id":"https://openalex.org/keywords/claudication","display_name":"claudication","score":0.7419999837875366}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9698441624641418},{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.6193174719810486},{"id":"https://openalex.org/C2780959883","wikidata":"https://www.wikidata.org/wiki/Q111146","display_name":"Hematocrit","level":2,"score":0.5832615494728088},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4907327890396118},{"id":"https://openalex.org/C2776940978","wikidata":"https://www.wikidata.org/wiki/Q34956","display_name":"Vitamin","level":2,"score":0.4621165096759796},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.4620928168296814},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.4548301696777344},{"id":"https://openalex.org/C2776351790","wikidata":"https://www.wikidata.org/wiki/Q417351","display_name":"Oxalate","level":2,"score":0.43111658096313477},{"id":"https://openalex.org/C2776422910","wikidata":"https://www.wikidata.org/wiki/Q612681","display_name":"Anuria","level":2,"score":0.41055500507354736},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2830676734447479},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001205","descriptor_name":"Ascorbic Acid","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D001205","descriptor_name":"Ascorbic Acid","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007263","descriptor_name":"Infusions, Parenteral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007676","descriptor_name":"Kidney Failure, Chronic","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:6471294","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6471294","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA","raw_type":"Case Reports"},{"id":"mag:2042616366","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6471294","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4382070590","https://openalex.org/W4417137684","https://openalex.org/W7214931209","https://openalex.org/W2053350878","https://openalex.org/W1986606117","https://openalex.org/W2891322534","https://openalex.org/W2765820494","https://openalex.org/W3006394393","https://openalex.org/W1973182399","https://openalex.org/W2084818988"],"abstract_inverted_index":{"To":[0,91],"the":[1,9,70,126],"Editor.\u2014":[2],"We":[4],"feel":[5],"compelled":[6],"to":[7,55,74,153],"report":[8],"complications":[10],"of":[11,24,43,62,99,107,113,115,143],"high-dose":[12],"vitamin":[13,108],"C":[14,109],"infusion":[15,127],"in":[16,35,110,118],"patients":[17,36],"with":[18,37,50],"renal":[19,33,39,52],"insufficiency.":[20,40],"Vitamin":[21],"C,":[22],"one":[23],"whose":[25],"main":[26],"metabolites":[27],"is":[28],"oxalate,":[29],"can":[30],"produce":[31],"permanent":[32],"failure":[34],"preexisting":[38],"Report":[42],"a":[44,56],"Case.\u2014":[45],"A":[47],"70-year-old":[48],"man":[49],"documented":[51],"insufficiency":[53],"came":[54],"chelation":[57],"therapy":[58],"center":[59],"for":[60,94,120],"treatment":[61],"claudication.":[63],"Previous":[64],"testing":[65],"(one":[66],"day":[67],"before)":[68],"showed":[69],"serum":[71,86],"creatinine":[72,80],"level":[73],"be":[75,92],"5.0":[76],"mg/dL.":[77],"An":[78],"estimated":[79],"clearance":[81],"was":[82,89,103,151],"19":[83],"mL/min.":[84],"The":[85,123,149],"hematocrit":[87],"value":[88],"29.4%.":[90],"prepared":[93],"chelation\u2014the":[95],"intravenous":[96],"(IV)":[97],"administration":[98],"edetic":[100],"acid\u2014the":[101],"patient":[102,124,150],"given":[104],"2.5":[105],"g":[106],"500":[111],"mL":[112,142],"solution":[114],"5%":[116],"dextrose":[117],"water":[119],"five":[121],"hours.":[122],"tolerated":[125],"well;":[128],"however,":[129],"12":[130],"hours":[131],"later":[132],"he":[133],"experienced":[134],"severe":[135],"lancinating":[136],"bilateral":[137],"flank":[138],"pain,":[139],"passed":[140],"3":[141],"hematuria,":[144],"and":[145],"became":[146],"anuric.":[147],"transferred":[152]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}