{"id":"https://openalex.org/W2042382908","doi":"https://doi.org/10.1590/s1806-37132015000004414","title":"Uncoupling protein-2 mRNA expression in mice subjected to intermittent hypoxia","display_name":"Uncoupling protein-2 mRNA expression in mice subjected to intermittent hypoxia","publication_year":2015,"publication_date":"2015-04-16","ids":{"openalex":"https://openalex.org/W2042382908","doi":"https://doi.org/10.1590/s1806-37132015000004414","mag":"2042382908","pmid":"https://pubmed.ncbi.nlm.nih.gov/25909153","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4428854"},"language":"en","primary_location":{"id":"doi:10.1590/s1806-37132015000004414","doi":"https://doi.org/10.1590/s1806-37132015000004414","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s1806-37132015000004414","pdf_url":"https://www.scielo.br/j/jbpneu/a/cMM3tXH4w3GVtvKxYMnfVtB/?lang=en&format=pdf","source":{"id":"https://openalex.org/S143346047","display_name":"Jornal Brasileiro de Pneumologia","issn_l":"1806-3713","issn":["1806-3713","1806-3756"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","norway-1","oarl","poland-40","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310312248","host_organization_name":"Sociedade Brasileira de Pneumologia e Tisiologia","host_organization_lineage":["https://openalex.org/P4310312248"],"host_organization_lineage_names":["Sociedade Brasileira de Pneumologia e Tisiologia"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Jornal Brasileiro de Pneumologia","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.scielo.br/j/jbpneu/a/cMM3tXH4w3GVtvKxYMnfVtB/?lang=en&format=pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009593420","display_name":"Luciana Rodrigues Vieira","orcid":"https://orcid.org/0000-0003-2711-9020","observed_orcids":["https://orcid.org/0000-0003-2711-9020"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Luciana Rodrigues Vieira","raw_affiliation_strings":["Federal University of Rio Grande do Sul, Brazil","Federal University of Rio Grande do Sul, Porto Alegre, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal University of Rio Grande do Sul, Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Federal University of Rio Grande do Sul, Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041606985","display_name":"D\u00eanis Martinez","orcid":"https://orcid.org/0000-0002-3578-0372","observed_orcids":["https://orcid.org/0000-0002-3578-0372"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Denis Martinez","raw_affiliation_strings":["Federal University of Rio Grande do Sul, Brazil","School of Medicine, Federal University of Rio Grande Do Sul , Porto Alegre, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal University of Rio Grande do Sul, Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"School of Medicine, Federal University of Rio Grande Do Sul , Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047304453","display_name":"Luiz Felipe Forgiarini","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Luiz Felipe Forgiarini","raw_affiliation_strings":["Faculdade Anhanguera de Pelotas, Brazil","Faculdade Anhanguera de Pelotas, Pelotas, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculdade Anhanguera de Pelotas, Brazil","institution_ids":[]},{"raw_affiliation_string":"Faculdade Anhanguera de Pelotas, Pelotas, Brazil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034599449","display_name":"Darlan Pase da Rosa","orcid":"https://orcid.org/0000-0003-2492-7540","observed_orcids":["https://orcid.org/0000-0003-2492-7540"]},"institutions":[{"id":"https://openalex.org/I51882195","display_name":"Universidade Luterana do Brasil","ror":"https://ror.org/00kde4z41","country_code":"BR","type":"education","lineage":["https://openalex.org/I51882195"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Darlan Pase da Rosa","raw_affiliation_strings":["Lutheran University of Brazil, Brazil","Lutheran University of Brazil, Canoas, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lutheran University of Brazil, Brazil","institution_ids":["https://openalex.org/I51882195"]},{"raw_affiliation_string":"Lutheran University of Brazil, Canoas, Brazil","institution_ids":["https://openalex.org/I51882195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108291899","display_name":"Gustavo Alfredo Ochs de Mu\u00f1oz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Gustavo Alfredo Ochs de Mu\u00f1oz","raw_affiliation_strings":["Federal University of Rio Grande do Sul, Brazil","Federal University of Rio Grande do Sul, Porto Alegre, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal University of Rio Grande do Sul, Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Federal University of Rio Grande do Sul, Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000477481","display_name":"Micheli Fagundes","orcid":"https://orcid.org/0000-0001-9418-2842","observed_orcids":["https://orcid.org/0000-0001-9418-2842"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Micheli Fagundes","raw_affiliation_strings":["Federal University of Rio Grande do Sul, Brazil","Federal University of Rio Grande do Sul, Porto Alegre, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal University of Rio Grande do Sul, Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Federal University of Rio Grande do Sul, Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108650683","display_name":"Emerson Ferreira Martins","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Emerson Ferreira Martins","raw_affiliation_strings":["Federal University of Rio Grande do Sul, Brazil","Federal University of Rio Grande do Sul, Porto Alegre, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal University of Rio Grande do Sul, Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Federal University of Rio Grande do Sul, Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090408586","display_name":"Carolina Caruccio Montanari","orcid":"https://orcid.org/0000-0003-2769-5407","observed_orcids":["https://orcid.org/0000-0003-2769-5407"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Carolina Caruccio Montanari","raw_affiliation_strings":["Federal University of Rio Grande do Sul, Brazil","Federal University of Rio Grande do Sul, Porto Alegre, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal University of Rio Grande do Sul, Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Federal University of Rio Grande do Sul, Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112019165","display_name":"Cintia Zappe Fiori","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Cintia Zappe Fiori","raw_affiliation_strings":["Federal University of Rio Grande do Sul, Brazil","Federal University of Rio Grande do Sul, Porto Alegre, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal University of Rio Grande do Sul, Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Federal University of Rio Grande do Sul, Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.07797141,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"41","issue":"2","first_page":"167","last_page":"174"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.5810999870300293,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.5810999870300293,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":0.388700008392334,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.005799999926239252,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ucp2","display_name":"UCP2","score":0.9769999980926514},{"id":"https://openalex.org/keywords/intermittent-hypoxia","display_name":"intermittent hypoxia","score":0.9980000257492065},{"id":"https://openalex.org/keywords/obstructive-sleep-apnea","display_name":"obstructive sleep apnea","score":0.9919999837875366},{"id":"https://openalex.org/keywords/pancreatic-islets","display_name":"pancreatic islets","score":0.9399999976158142},{"id":"https://openalex.org/keywords/beta-cell-function","display_name":"beta-cell function","score":0.8429999947547913},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.9900000095367432},{"id":"https://openalex.org/keywords/fasting-insulin","display_name":"fasting insulin","score":0.6150000095367432},{"id":"https://openalex.org/keywords/glycemic-control","display_name":"glycemic control","score":0.8140000104904175},{"id":"https://openalex.org/keywords/lipid-profile","display_name":"lipid profile","score":0.6499999761581421}],"concepts":[{"id":"https://openalex.org/C2780796939","wikidata":"https://www.wikidata.org/wiki/Q25326656","display_name":"Intermittent hypoxia","level":3,"score":0.8996902704238892},{"id":"https://openalex.org/C7836513","wikidata":"https://www.wikidata.org/wiki/Q1641506","display_name":"Hypoxia (environmental)","level":3,"score":0.8188865184783936},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6915038824081421},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6781831383705139},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6415491104125977},{"id":"https://openalex.org/C2778563252","wikidata":"https://www.wikidata.org/wiki/Q170617","display_name":"Glucagon","level":3,"score":0.5713558197021484},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.5572614073753357},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.5056240558624268},{"id":"https://openalex.org/C2779855799","wikidata":"https://www.wikidata.org/wiki/Q728309","display_name":"Pancreatic islets","level":4,"score":0.4322178363800049},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.41746050119400024},{"id":"https://openalex.org/C165220095","wikidata":"https://www.wikidata.org/wiki/Q207524","display_name":"Islet","level":3,"score":0.41417789459228516},{"id":"https://openalex.org/C2776006263","wikidata":"https://www.wikidata.org/wiki/Q16606552","display_name":"Obstructive sleep apnea","level":2,"score":0.23412352800369263},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22799450159072876},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.15561869740486145},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.1500146985054016},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08701997995376587},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.056829094886779785},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000071246","descriptor_name":"Uncoupling Protein 2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000860","descriptor_name":"Hypoxia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000860","descriptor_name":"Hypoxia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007333","descriptor_name":"Insulin Resistance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007473","descriptor_name":"Ion Channels","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007473","descriptor_name":"Ion Channels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007515","descriptor_name":"Islets of Langerhans","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D024101","descriptor_name":"Mitochondrial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D024101","descriptor_name":"Mitochondrial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":8,"locations":[{"id":"doi:10.1590/s1806-37132015000004414","doi":"https://doi.org/10.1590/s1806-37132015000004414","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s1806-37132015000004414","pdf_url":"https://www.scielo.br/j/jbpneu/a/cMM3tXH4w3GVtvKxYMnfVtB/?lang=en&format=pdf","source":{"id":"https://openalex.org/S143346047","display_name":"Jornal Brasileiro de Pneumologia","issn_l":"1806-3713","issn":["1806-3713","1806-3756"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","norway-1","oarl","poland-40","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310312248","host_organization_name":"Sociedade Brasileira de Pneumologia e Tisiologia","host_organization_lineage":["https://openalex.org/P4310312248"],"host_organization_lineage_names":["Sociedade Brasileira de Pneumologia e Tisiologia"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Jornal Brasileiro de Pneumologia","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4428854","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4428854","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Bras Pneumol","raw_type":"Text"},{"id":"pmid:25909153","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25909153","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia","raw_type":"Journal Article"},{"id":"pmh:oai:scielo:S1806-37132015000200167","doi":null,"is_oa":true,"landing_page_url":"http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132015000200167","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Jornal Brasileiro de Pneumologia v.41 n.2 2015","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:www.lume.ufrgs.br:10183/117580","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10183/117580","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"instacron:UFRGS","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:americanae.aecid.es:2452720","doi":null,"is_oa":true,"landing_page_url":"http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132015000200167","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Jornal Brasileiro de Pneumologia v.41 n.2 2015","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:a602cd88833045e88c78f29cdf50336d","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/a602cd88833045e88c78f29cdf50336d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Jornal Brasileiro de Pneumologia, Vol 41, Iss 2, Pp 167-174 (2015)","raw_type":"article"},{"id":"mag:2506639276","doi":null,"is_oa":false,"landing_page_url":"https://www.jornaldepneumologia.com.br/audiencia_pdf.asp?aid2=2390&nomeArquivo=2015_41_2_9_english.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1590/s1806-37132015000004414","doi":"https://doi.org/10.1590/s1806-37132015000004414","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s1806-37132015000004414","pdf_url":"https://www.scielo.br/j/jbpneu/a/cMM3tXH4w3GVtvKxYMnfVtB/?lang=en&format=pdf","source":{"id":"https://openalex.org/S143346047","display_name":"Jornal Brasileiro de Pneumologia","issn_l":"1806-3713","issn":["1806-3713","1806-3756"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","norway-1","oarl","poland-40","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310312248","host_organization_name":"Sociedade Brasileira de Pneumologia e Tisiologia","host_organization_lineage":["https://openalex.org/P4310312248"],"host_organization_lineage_names":["Sociedade Brasileira de Pneumologia e Tisiologia"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Jornal Brasileiro de Pneumologia","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9922999739646912,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"},{"id":"https://openalex.org/F4320322177","display_name":"Hospital de Cl\u00ednicas de Porto Alegre","ror":"https://ror.org/010we4y38"},{"id":"https://openalex.org/F4320324374","display_name":"Funda\u00e7\u00e3o Instituto de Pesquisas Econ\u00f4micas","ror":"https://ror.org/00ngrh496"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2042382908.pdf","grobid_xml":"https://content.openalex.org/works/W2042382908.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W82112906","https://openalex.org/W1485905810","https://openalex.org/W1534256759","https://openalex.org/W1767473471","https://openalex.org/W1992485652","https://openalex.org/W1999346088","https://openalex.org/W2013702730","https://openalex.org/W2017602185","https://openalex.org/W2025308968","https://openalex.org/W2027358194","https://openalex.org/W2042592767","https://openalex.org/W2077564898","https://openalex.org/W2078117941","https://openalex.org/W2079520227","https://openalex.org/W2081226646","https://openalex.org/W2101870887","https://openalex.org/W2107277218","https://openalex.org/W2114360920","https://openalex.org/W2116404316","https://openalex.org/W2121096332","https://openalex.org/W2124620553","https://openalex.org/W2125842647","https://openalex.org/W2130185420","https://openalex.org/W2160234571","https://openalex.org/W2161444884","https://openalex.org/W2471195096","https://openalex.org/W2521718428","https://openalex.org/W2546647298","https://openalex.org/W2607031541","https://openalex.org/W2732223081","https://openalex.org/W3023775830"],"related_works":["https://openalex.org/W2506639276","https://openalex.org/W7047290858","https://openalex.org/W150449371","https://openalex.org/W2120443496","https://openalex.org/W2403974976","https://openalex.org/W1559525331","https://openalex.org/W2070679214","https://openalex.org/W1485905810","https://openalex.org/W4399686332","https://openalex.org/W57222218"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1,231],"investigate":[2],"the":[3,77,98,105,114,135,140,152,157,175,178,204,211,217,236,240,261,267],"effect":[4,241],"of":[5,9,16,66,79,125,167,203,216,221,239,242,260,270],"intermittent":[6,45,57,182,243],"hypoxia-a":[7],"model":[8,165],"obstructive":[10],"sleep":[11],"apnea":[12],"(OSA)-on":[13],"pancreatic":[14,129,195],"expression":[15],"uncoupling":[17],"protein-2":[18],"(UCP2),":[19],"as":[20,22],"well":[21],"on":[23,245],"glycemic":[24,268],"and":[25,69,97,192,223,228],"lipid":[26],"profiles,":[27],"in":[28,128,134,139,151,156,172,214,256,266],"C57BL":[29,40],"mice.":[30],"METHODS:":[31],"For":[32],"8":[33,83],"h/day":[34],"over":[35,104],"a":[36,51],"35-day":[37],"period,":[38],"male":[39],"mice":[41,62,179],"were":[42,89,110],"exposed":[43,90,180],"to":[44,50,63,82,91,112,181],"hypoxia":[46,58,141,153,183,244],"(hypoxia":[47],"group)":[48],"or":[49,219],"sham":[52],"procedure":[53],"(normoxia":[54],"group).":[55],"The":[56,163],"condition":[59],"involved":[60],"exposing":[61],"an":[64],"atmosphere":[65],"92%":[67],"N":[68],"8%":[70],"CO2":[71],"for":[72,94,226],"30":[73,95],"s,":[74],"progressively":[75],"reducing":[76],"fraction":[78],"inspired":[80],"oxygen":[81],"\u00b1":[84],"1%,":[85],"after":[86],"which":[87],"they":[88],"room":[92],"air":[93],"s":[96],"cycle":[99],"was":[100,118,131,149],"repeated":[101],"(480":[102],"cycles":[103],"8-h":[106],"experimental":[107],"period).":[108],"Pancreases":[109],"dissected":[111],"isolate":[113],"islets.":[115],"Real-time":[116],"PCR":[117],"performed":[119],"with":[120,174],"TaqMan":[121],"assays.":[122],"RESULTS:":[123],"Expression":[124],"UCP2":[126,246,252,264],"mRNA":[127],"islets":[130,205],"20%":[132],"higher":[133,150,194],"normoxia":[136,158],"group":[137,142,154,159],"than":[138,155],"(p":[143,160,189,198],"=":[144,161,190,199],"0.11).":[145],"Fasting":[146],"serum":[147],"insulin":[148,168,187,227,254],"0.01).":[162,200],"homeostasis":[164],"assessment":[166],"resistance":[169,188],"indicated":[170],"that,":[171],"comparison":[173],"control":[176,269],"mice,":[177],"showed":[184,206],"15%":[185],"lower":[186],"0.09)":[191],"21%":[193],"\u03b2-cell":[196,224],"function":[197],"Immunohistochemical":[201],"staining":[202,225],"no":[207],"significant":[208],"differences":[209],"between":[210],"two":[212],"groups":[213],"terms":[215],"area":[218],"intensity":[220],"\u03b1-":[222],"glucagon.":[229],"CONCLUSIONS:":[230],"our":[232],"knowledge,":[233],"this":[234],"is":[235,273],"first":[237],"report":[238],"expression.":[247],"Our":[248],"findings":[249],"suggest":[250],"that":[251,263],"regulates":[253],"production":[255],"OSA.":[257],"Further":[258],"study":[259],"role":[262],"plays":[265],"OSA":[271],"patients":[272],"warranted.":[274]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}