{"id":"https://openalex.org/W2041861925","doi":"https://doi.org/10.1016/s0300-9084(74)80503-1","title":"Pig brain 4-aminobutyrate 2-ketoglutarate transaminase. Purification, kinetics and physical properties","display_name":"Pig brain 4-aminobutyrate 2-ketoglutarate transaminase. Purification, kinetics and physical properties","publication_year":1974,"publication_date":"1974-09-01","ids":{"openalex":"https://openalex.org/W2041861925","doi":"https://doi.org/10.1016/s0300-9084(74)80503-1","mag":"2041861925","pmid":"https://pubmed.ncbi.nlm.nih.gov/4447797"},"language":"en","primary_location":{"id":"doi:10.1016/s0300-9084(74)80503-1","doi":"https://doi.org/10.1016/s0300-9084(74)80503-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0300-9084(74)80503-1","pdf_url":null,"source":{"id":"https://openalex.org/S75247133","display_name":"Biochimie","issn_l":"0037-9042","issn":["0037-9042","0300-9084","1638-6183"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimie","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110515349","display_name":"M. Tardy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3019246885","display_name":"Centre Hospitalier Universitaire Henri-Mondor","ror":"https://ror.org/04m61mj84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019246885"]},{"id":"https://openalex.org/I4210130325","display_name":"H\u00f4pitaux Universitaires Henri-Mondor","ror":"https://ror.org/033yb0967","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210130325"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marcienne Bloch-Tardy","raw_affiliation_strings":["D\u00e9partement de Biochimie, C.H.U. Henri-Mondor, 94010 Cr\u00e9teil, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"D\u00e9partement de Biochimie, C.H.U. Henri-Mondor, 94010 Cr\u00e9teil, France","institution_ids":["https://openalex.org/I3019246885","https://openalex.org/I4210130325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033036994","display_name":"Bernadette Rolland","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3019246885","display_name":"Centre Hospitalier Universitaire Henri-Mondor","ror":"https://ror.org/04m61mj84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019246885"]},{"id":"https://openalex.org/I4210130325","display_name":"H\u00f4pitaux Universitaires Henri-Mondor","ror":"https://ror.org/033yb0967","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210130325"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Bernadette Rolland","raw_affiliation_strings":["D\u00e9partement de Biochimie, C.H.U. Henri-Mondor, 94010 Cr\u00e9teil, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"D\u00e9partement de Biochimie, C.H.U. Henri-Mondor, 94010 Cr\u00e9teil, France","institution_ids":["https://openalex.org/I3019246885","https://openalex.org/I4210130325"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045644708","display_name":"Pierre Gonnard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3019246885","display_name":"Centre Hospitalier Universitaire Henri-Mondor","ror":"https://ror.org/04m61mj84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019246885"]},{"id":"https://openalex.org/I4210130325","display_name":"H\u00f4pitaux Universitaires Henri-Mondor","ror":"https://ror.org/033yb0967","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210130325"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Pierre Gonnard","raw_affiliation_strings":["D\u00e9partement de Biochimie, C.H.U. Henri-Mondor, 94010 Cr\u00e9teil, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"D\u00e9partement de Biochimie, C.H.U. Henri-Mondor, 94010 Cr\u00e9teil, France","institution_ids":["https://openalex.org/I3019246885","https://openalex.org/I4210130325"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3110,"currency":"USD","value_usd":3110},"apc_paid":null,"fwci":1.8749,"has_fulltext":false,"cited_by_count":51,"citation_normalized_percentile":{"value":0.83101207,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"56","issue":"6-7","first_page":"823","last_page":"832"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12770","display_name":"Amino Acid Enzymes and Metabolism","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12770","display_name":"Amino Acid Enzymes and Metabolism","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.01119999960064888,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13142","display_name":"GABA and Rice Research","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gaba-transaminase","display_name":"GABA transaminase","score":0.890999972820282},{"id":"https://openalex.org/keywords/enzyme-purification","display_name":"enzyme purification","score":0.7820000052452087},{"id":"https://openalex.org/keywords/pig-brain","display_name":"pig brain","score":0.7599999904632568},{"id":"https://openalex.org/keywords/enzyme-kinetics","display_name":"enzyme kinetics","score":0.9470000267028809},{"id":"https://openalex.org/keywords/molecular-weight","display_name":"molecular weight","score":0.6859999895095825},{"id":"https://openalex.org/keywords/enzyme-dimer","display_name":"enzyme dimer","score":0.574999988079071},{"id":"https://openalex.org/keywords/optimal-ph","display_name":"pH optimum","score":0.6039999723434448},{"id":"https://openalex.org/keywords/aspartate-aminotransferase","display_name":"aspartate aminotransferase","score":0.8659999966621399},{"id":"https://openalex.org/keywords/enzyme-complex","display_name":"enzyme complex","score":0.5509999990463257},{"id":"https://openalex.org/keywords/deae-cellulose-chromatography","display_name":"DEAE-cellulose chromatography","score":0.8209999799728394}],"concepts":[{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.7293063402175903},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7271528244018555},{"id":"https://openalex.org/C163994747","wikidata":"https://www.wikidata.org/wiki/Q2916358","display_name":"Sephadex","level":3,"score":0.694122850894928},{"id":"https://openalex.org/C193363816","wikidata":"https://www.wikidata.org/wiki/Q1617865","display_name":"Size-exclusion chromatography","level":3,"score":0.5889703631401062},{"id":"https://openalex.org/C101660505","wikidata":"https://www.wikidata.org/wiki/Q898301","display_name":"Polyacrylamide gel electrophoresis","level":3,"score":0.5513460636138916},{"id":"https://openalex.org/C2776428949","wikidata":"https://www.wikidata.org/wiki/Q18814659","display_name":"Ammonium sulfate precipitation","level":4,"score":0.5216044187545776},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.43322402238845825},{"id":"https://openalex.org/C116084860","wikidata":"https://www.wikidata.org/wiki/Q48255","display_name":"Gel electrophoresis","level":2,"score":0.4162777066230774},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3107258677482605}],"mesh":[{"descriptor_ui":"D000613","descriptor_name":"Aminobutyrates","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000637","descriptor_name":"Transaminases","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D000637","descriptor_name":"Transaminases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001219","descriptor_name":"Aspartate Aminotransferases","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D002845","descriptor_name":"Chromatography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002848","descriptor_name":"Chromatography, DEAE-Cellulose","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002850","descriptor_name":"Chromatography, Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004591","descriptor_name":"Electrophoresis, Polyacrylamide Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007656","descriptor_name":"Ketoglutaric Acids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008970","descriptor_name":"Molecular Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009097","descriptor_name":"Multienzyme Complexes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0300-9084(74)80503-1","doi":"https://doi.org/10.1016/s0300-9084(74)80503-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0300-9084(74)80503-1","pdf_url":null,"source":{"id":"https://openalex.org/S75247133","display_name":"Biochimie","issn_l":"0037-9042","issn":["0037-9042","0300-9084","1638-6183"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimie","raw_type":"journal-article"},{"id":"pmid:4447797","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4447797","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimie","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W122606267","https://openalex.org/W136465957","https://openalex.org/W1494893977","https://openalex.org/W1625660792","https://openalex.org/W1775749144","https://openalex.org/W1970202366","https://openalex.org/W1985768825","https://openalex.org/W2005349247","https://openalex.org/W2081828201","https://openalex.org/W2111301002"],"related_works":["https://openalex.org/W1971565928","https://openalex.org/W4390472492","https://openalex.org/W2005349247","https://openalex.org/W2021607538","https://openalex.org/W2262321424","https://openalex.org/W1974569524","https://openalex.org/W2238646708","https://openalex.org/W1970202366","https://openalex.org/W2220822345","https://openalex.org/W2021599018"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}