{"id":"https://openalex.org/W2041660100","doi":"https://doi.org/10.4236/abc.2013.32023","title":"Cancer induction pathways and HF-EMF irradiation","display_name":"Cancer induction pathways and HF-EMF irradiation","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2041660100","doi":"https://doi.org/10.4236/abc.2013.32023","mag":"2041660100"},"language":"en","primary_location":{"id":"doi:10.4236/abc.2013.32023","doi":"https://doi.org/10.4236/abc.2013.32023","is_oa":true,"landing_page_url":"https://doi.org/10.4236/abc.2013.32023","pdf_url":"https://content.scirp.org/pdf/abc_2013043013050428.pdf","source":{"id":"https://openalex.org/S2764468471","display_name":"Advances in Biological Chemistry","issn_l":"2162-2183","issn":["2162-2183","2162-2191"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320480","host_organization_name":"Scientific Research Publishing","host_organization_lineage":["https://openalex.org/P4310320480"],"host_organization_lineage_names":["Scientific Research Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://content.scirp.org/pdf/abc_2013043013050428.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053895979","display_name":"G\u00e9rard Ledoigt","orcid":"https://orcid.org/0000-0001-8618-2746","observed_orcids":["https://orcid.org/0000-0001-8618-2746"]},"institutions":[{"id":"https://openalex.org/I4387154544","display_name":"Institut National de la Recherche Agronomique","ror":"https://ror.org/01x3gbx83","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668","https://openalex.org/I4387154544"]},{"id":"https://openalex.org/I4405258658","display_name":"Universit\u00e9 Blaise Pascal","ror":"https://ror.org/0119hgk08","country_code":"FR","type":"education","lineage":["https://openalex.org/I198244214","https://openalex.org/I4405258658"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"G\u00e9rard Ledoigt","raw_affiliation_strings":["Clermont-Universit\u00e9 , UMR PIAF Universit\u00e9-INRA , Blaise-Pascal University , Campus Universitaire des C\u00e9zeaux , Landais ; Aubiere Cedex , France","[Blaise Pascal University]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clermont-Universit\u00e9 , UMR PIAF Universit\u00e9-INRA , Blaise-Pascal University , Campus Universitaire des C\u00e9zeaux , Landais ; Aubiere Cedex , France","institution_ids":["https://openalex.org/I4387154544"]},{"raw_affiliation_string":"[Blaise Pascal University]","institution_ids":["https://openalex.org/I4405258658"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062167452","display_name":"D Belpomme","orcid":"https://orcid.org/0000-0002-9132-2077","observed_orcids":["https://orcid.org/0000-0002-9132-2077"]},"institutions":[{"id":"https://openalex.org/I4387156284","display_name":"Universit\u00e9 Paris Descartes","ror":"https://ror.org/0220k9r37","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241","https://openalex.org/I4387156284"]},{"id":"https://openalex.org/I4405272305","display_name":"Association pour la Recherche Th\u00e9rapeutique Anti-Canc\u00e9reuse","ror":"https://ror.org/03ymhyb33","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4405272305"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Dominique Belpomme","raw_affiliation_strings":["Paris-Descartes University Hospital, Medical Oncology Department, Association for Research and Treatment against Cancer (ARTAC), Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Paris-Descartes University Hospital, Medical Oncology Department, Association for Research and Treatment against Cancer (ARTAC), Paris, France","institution_ids":["https://openalex.org/I4387156284","https://openalex.org/I4405272305"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1752,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.51975052,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"03","issue":"02","first_page":"177","last_page":"186"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10874","display_name":"Electromagnetic Fields and Biological Effects","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10874","display_name":"Electromagnetic Fields and Biological Effects","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12976","display_name":"Magnetic and Electromagnetic Effects","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1102","display_name":"Agronomy and Crop Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/high-frequency-electromagnetic-fields","display_name":"high-frequency electromagnetic fields","score":0.890999972820282},{"id":"https://openalex.org/keywords/mobile-phone-radiation","display_name":"mobile phone radiation","score":0.8240000009536743},{"id":"https://openalex.org/keywords/cancer-induction","display_name":"cancer induction","score":0.824999988079071},{"id":"https://openalex.org/keywords/epigenetic-effects","display_name":"epigenetic effects","score":0.5920000076293945},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.9049999713897705},{"id":"https://openalex.org/keywords/nadph-oxidase","display_name":"NADPH oxidase","score":0.9670000076293945},{"id":"https://openalex.org/keywords/calcium-signaling","display_name":"calcium signaling","score":0.7850000262260437},{"id":"https://openalex.org/keywords/nf-kappab-signaling","display_name":"NF-\u03baB signaling","score":0.9020000100135803},{"id":"https://openalex.org/keywords/chronic-inflammation","display_name":"chronic inflammation","score":0.7870000004768372},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"carcinogenesis","score":0.7059999704360962},{"id":"https://openalex.org/keywords/mobile-phone-use","display_name":"mobile phone use","score":0.5289999842643738}],"concepts":[{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.6395544409751892},{"id":"https://openalex.org/C2779719074","wikidata":"https://www.wikidata.org/wiki/Q2038057","display_name":"NADPH oxidase","level":3,"score":0.6122521758079529},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5703584551811218},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.5702773332595825},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.539976179599762},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.5209678411483765},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.511833131313324},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.5057051181793213},{"id":"https://openalex.org/C117717151","wikidata":"https://www.wikidata.org/wiki/Q3589155","display_name":"Epigenome","level":5,"score":0.4836048185825348},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.4762991666793823},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4611928462982178},{"id":"https://openalex.org/C51551487","wikidata":"https://www.wikidata.org/wiki/Q2043632","display_name":"p38 mitogen-activated protein kinases","level":4,"score":0.41560259461402893},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3054383099079132},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2862164080142975},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.25325292348861694},{"id":"https://openalex.org/C57074206","wikidata":"https://www.wikidata.org/wiki/Q14197552","display_name":"MAPK/ERK pathway","level":3,"score":0.16749107837677002},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.1328108012676239},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.12880173325538635},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09575793147087097},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.4236/abc.2013.32023","doi":"https://doi.org/10.4236/abc.2013.32023","is_oa":true,"landing_page_url":"https://doi.org/10.4236/abc.2013.32023","pdf_url":"https://content.scirp.org/pdf/abc_2013043013050428.pdf","source":{"id":"https://openalex.org/S2764468471","display_name":"Advances in Biological Chemistry","issn_l":"2162-2183","issn":["2162-2183","2162-2191"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320480","host_organization_name":"Scientific Research Publishing","host_organization_lineage":["https://openalex.org/P4310320480"],"host_organization_lineage_names":["Scientific Research Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Biological Chemistry","raw_type":"journal-article"},{"id":"mag:2304868003","doi":null,"is_oa":false,"landing_page_url":"http://emmind.net/openpapers_repos/Applied_Fields-Hazads/Microwave_Effects/MW_Reviews/2013_Cancer_induction_molecular_pathways_and_HF-EMF_irradiation.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.4236/abc.2013.32023","doi":"https://doi.org/10.4236/abc.2013.32023","is_oa":true,"landing_page_url":"https://doi.org/10.4236/abc.2013.32023","pdf_url":"https://content.scirp.org/pdf/abc_2013043013050428.pdf","source":{"id":"https://openalex.org/S2764468471","display_name":"Advances in Biological Chemistry","issn_l":"2162-2183","issn":["2162-2183","2162-2191"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320480","host_organization_name":"Scientific Research Publishing","host_organization_lineage":["https://openalex.org/P4310320480"],"host_organization_lineage_names":["Scientific Research Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320311432","display_name":"Association pour la Recherche Th\u00e9rapeutique Anti-Canc\u00e9reuse","ror":"https://ror.org/03ymhyb33"},{"id":"https://openalex.org/F4320312716","display_name":"Innovation, Science and Economic Development Canada","ror":"https://ror.org/03zp01h17"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2041660100.pdf","grobid_xml":"https://content.openalex.org/works/W2041660100.grobid-xml"},"referenced_works_count":90,"referenced_works":["https://openalex.org/W306915739","https://openalex.org/W1480357432","https://openalex.org/W1543746024","https://openalex.org/W1836453327","https://openalex.org/W1959834892","https://openalex.org/W1972466727","https://openalex.org/W1973714638","https://openalex.org/W1979047371","https://openalex.org/W1980188722","https://openalex.org/W1981545941","https://openalex.org/W1981876883","https://openalex.org/W1981972069","https://openalex.org/W1985824938","https://openalex.org/W1986494305","https://openalex.org/W1995933090","https://openalex.org/W1999240974","https://openalex.org/W1999257781","https://openalex.org/W1999493970","https://openalex.org/W2013155173","https://openalex.org/W2013683405","https://openalex.org/W2014845340","https://openalex.org/W2015178579","https://openalex.org/W2018896819","https://openalex.org/W2025369275","https://openalex.org/W2028036903","https://openalex.org/W2031214356","https://openalex.org/W2038713860","https://openalex.org/W2043051921","https://openalex.org/W2045225613","https://openalex.org/W2046056065","https://openalex.org/W2048553024","https://openalex.org/W2049816829","https://openalex.org/W2053946611","https://openalex.org/W2056579307","https://openalex.org/W2057143270","https://openalex.org/W2063081233","https://openalex.org/W2064956543","https://openalex.org/W2065792525","https://openalex.org/W2068560828","https://openalex.org/W2074596823","https://openalex.org/W2075036130","https://openalex.org/W2078721711","https://openalex.org/W2080589329","https://openalex.org/W2081748503","https://openalex.org/W2082560693","https://openalex.org/W2089997301","https://openalex.org/W2090023298","https://openalex.org/W2090450674","https://openalex.org/W2094313689","https://openalex.org/W2094665743","https://openalex.org/W2095130777","https://openalex.org/W2096694106","https://openalex.org/W2097227760","https://openalex.org/W2097308038","https://openalex.org/W2098533764","https://openalex.org/W2106656773","https://openalex.org/W2109402856","https://openalex.org/W2113389877","https://openalex.org/W2115764086","https://openalex.org/W2117584658","https://openalex.org/W2120434334","https://openalex.org/W2121079193","https://openalex.org/W2123105952","https://openalex.org/W2124561433","https://openalex.org/W2125011567","https://openalex.org/W2127298844","https://openalex.org/W2127364075","https://openalex.org/W2131464730","https://openalex.org/W2132478490","https://openalex.org/W2134720229","https://openalex.org/W2138936448","https://openalex.org/W2140238144","https://openalex.org/W2141290206","https://openalex.org/W2142384246","https://openalex.org/W2150275650","https://openalex.org/W2151245994","https://openalex.org/W2153114746","https://openalex.org/W2156823115","https://openalex.org/W2157458602","https://openalex.org/W2160679814","https://openalex.org/W2166119520","https://openalex.org/W2166781237","https://openalex.org/W2168756860","https://openalex.org/W2170215808","https://openalex.org/W2171540483","https://openalex.org/W2171865516","https://openalex.org/W2232313291","https://openalex.org/W2477993107","https://openalex.org/W4210892750","https://openalex.org/W4301671588"],"related_works":["https://openalex.org/W2304868003","https://openalex.org/W1982826145","https://openalex.org/W2048669869","https://openalex.org/W2327253281","https://openalex.org/W1981336695","https://openalex.org/W7167627638","https://openalex.org/W1982427477","https://openalex.org/W2038801526","https://openalex.org/W94036179","https://openalex.org/W2784134242"],"abstract_inverted_index":{"The":[0,99,111],"response":[1],"of":[2,7,32,53,66,125],"cells":[3],"to":[4,108],"different":[5],"types":[6],"electromagnetic":[8,19],"fields":[9],"can":[10,106],"be":[11],"induced":[12],"by":[13,44,122],"low-level":[14],"(athermal)":[15],"high":[16],"frequency":[17],"(HF)":[18],"field":[20],"(EMF)":[21],"exposure":[22,120],"associated":[23],"with":[24],"mobile":[25],"phone":[26],"technologies.":[27],"There":[28],"are":[29,83],"many":[30],"examples":[31],"biological":[33],"effects":[34],"involving":[35],"the":[36,51,57,95,114],"epigenome.":[37],"EMF":[38],"could":[39],"trigger":[40],"protein":[41],"activation":[42],"mediated":[43],"ligands,":[45],"such":[46],"as":[47],"Ca2+,":[48],"that":[49,71,82,101,116],"alter":[50,73],"conformation":[52],"binding":[54],"proteins,":[55],"especially":[56],"NADPH":[58],"plasmic":[59],"membrane":[60],"oxidase,":[61],"so":[62],"inducing":[63],"increased":[64],"formation":[65],"reactive":[67],"oxygen":[68],"species":[69],"(ROS)":[70],"may":[72,128],"proteomic":[74],"functions.":[75],"Classical":[76],"antiapoptotic":[77],"and":[78,90],"procarcinogenic":[79],"signaling":[80],"mechanisms":[81],"commonly":[84],"found":[85],"activated":[86],"in":[87,91],"human":[88],"malignancies":[89],"inflammation":[92,105],"mainly":[93],"involve":[94],"transcription":[96],"factor":[97],"NF-\u03baB.":[98],"microenvironment":[100],"exists":[102],"during":[103],"chronic":[104],"contribute":[107],"cancer":[109],"progression.":[110],"data":[112],"support":[113],"proposition":[115],"long":[117],"term":[118],"HF-EMF":[119],"caused":[121],"improper":[123],"use":[124],"cell":[126],"phones":[127],"potentially":[129],"cause":[130],"cancer.":[131]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}
