{"id":"https://openalex.org/W2041124367","doi":"https://doi.org/10.1016/0047-6374(81)90046-4","title":"Ageing studies in rat liver II. Patterns of cellular and cell-free protein synthesis from one to ten months of age","display_name":"Ageing studies in rat liver II. Patterns of cellular and cell-free protein synthesis from one to ten months of age","publication_year":1981,"publication_date":"1981-04-01","ids":{"openalex":"https://openalex.org/W2041124367","doi":"https://doi.org/10.1016/0047-6374(81)90046-4","mag":"2041124367","pmid":"https://pubmed.ncbi.nlm.nih.gov/6165871"},"language":"en","primary_location":{"id":"doi:10.1016/0047-6374(81)90046-4","doi":"https://doi.org/10.1016/0047-6374(81)90046-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0047-6374(81)90046-4","pdf_url":null,"source":{"id":"https://openalex.org/S6761461","display_name":"Mechanisms of Ageing and Development","issn_l":"0047-6374","issn":["0047-6374","1872-6216"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mechanisms of Ageing and Development","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113717533","display_name":"Robert R. Stone","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1298060332","display_name":"New York State Department of Health","ror":"https://ror.org/04hf5kq57","country_code":"US","type":"government","lineage":["https://openalex.org/I1298060332"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert R. Stone","raw_affiliation_strings":["New York State Department of Health, Albany, New York 12201 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York State Department of Health, Albany, New York 12201 U.S.A","institution_ids":["https://openalex.org/I1298060332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068505847","display_name":"Frank Maley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1298060332","display_name":"New York State Department of Health","ror":"https://ror.org/04hf5kq57","country_code":"US","type":"government","lineage":["https://openalex.org/I1298060332"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Frank Maley","raw_affiliation_strings":["New York State Department of Health, Albany, New York 12201 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York State Department of Health, Albany, New York 12201 U.S.A","institution_ids":["https://openalex.org/I1298060332"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008755693","display_name":"Robert B. Trimble","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1298060332","display_name":"New York State Department of Health","ror":"https://ror.org/04hf5kq57","country_code":"US","type":"government","lineage":["https://openalex.org/I1298060332"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert B. Trimble","raw_affiliation_strings":["New York State Department of Health, Albany, New York 12201 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York State Department of Health, Albany, New York 12201 U.S.A","institution_ids":["https://openalex.org/I1298060332"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1298060332"],"apc_list":{"value":4780,"currency":"USD","value_usd":4780},"apc_paid":null,"fwci":0.1769,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.43426936,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"15","issue":"4","first_page":"423","last_page":"439"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.7294999957084656,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.7294999957084656,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10676","display_name":"Genetics, Aging, and Longevity in Model Organisms","score":0.23829999566078186,"subfield":{"id":"https://openalex.org/subfields/1302","display_name":"Aging"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.01889999955892563,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hepatic-protein-synthesis","display_name":"hepatic protein synthesis","score":0.8100000023841858},{"id":"https://openalex.org/keywords/hepatocytes","display_name":"hepatocytes","score":0.7509999871253967},{"id":"https://openalex.org/keywords/poly-a-rna","display_name":"polyadenylated RNA","score":0.8040000200271606},{"id":"https://openalex.org/keywords/polysomes","display_name":"polysomes","score":0.8510000109672546},{"id":"https://openalex.org/keywords/mrna-translation","display_name":"mRNA translation","score":0.47699999809265137},{"id":"https://openalex.org/keywords/translation-elongation","display_name":"translation elongation","score":0.9150000214576721},{"id":"https://openalex.org/keywords/fischer-344-rats","display_name":"F344 rats","score":0.7739999890327454}],"concepts":[{"id":"https://openalex.org/C500499127","wikidata":"https://www.wikidata.org/wiki/Q332154","display_name":"Ageing","level":2,"score":0.8370656967163086},{"id":"https://openalex.org/C522857546","wikidata":"https://www.wikidata.org/wiki/Q2070979","display_name":"Senescence","level":2,"score":0.5106235146522522},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4718732237815857},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.38074791431427},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3689693212509155},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.34311816096305847},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.30453813076019287},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.18871569633483887}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001345","descriptor_name":"Autoradiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002474","descriptor_name":"Cell-Free System","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004591","descriptor_name":"Electrophoresis, Polyacrylamide Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007525","descriptor_name":"Isoelectric Focusing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011061","descriptor_name":"Poly A","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D011061","descriptor_name":"Poly A","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014176","descriptor_name":"Protein Biosynthesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0047-6374(81)90046-4","doi":"https://doi.org/10.1016/0047-6374(81)90046-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0047-6374(81)90046-4","pdf_url":null,"source":{"id":"https://openalex.org/S6761461","display_name":"Mechanisms of Ageing and Development","issn_l":"0047-6374","issn":["0047-6374","1872-6216"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mechanisms of Ageing and Development","raw_type":"journal-article"},{"id":"pmid:6165871","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6165871","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mechanisms of ageing and development","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4000000059604645,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332505","display_name":"U.S. Public Health Service","ror":"https://ror.org/05xf94514"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W1512436818","https://openalex.org/W1542576388","https://openalex.org/W1568700466","https://openalex.org/W1606423922","https://openalex.org/W1653073514","https://openalex.org/W1888046396","https://openalex.org/W1967345733","https://openalex.org/W1970403529","https://openalex.org/W1972487349","https://openalex.org/W1978042332","https://openalex.org/W1985437709","https://openalex.org/W1989058632","https://openalex.org/W1993529267","https://openalex.org/W1995394583","https://openalex.org/W1997254064","https://openalex.org/W2004564867","https://openalex.org/W2006572376","https://openalex.org/W2019410877","https://openalex.org/W2034277598","https://openalex.org/W2037112178","https://openalex.org/W2038019779","https://openalex.org/W2040213983","https://openalex.org/W2041088807","https://openalex.org/W2049776320","https://openalex.org/W2060619551","https://openalex.org/W2063697224","https://openalex.org/W2066160869","https://openalex.org/W2071702363","https://openalex.org/W2072482644","https://openalex.org/W2075573504","https://openalex.org/W2082221845","https://openalex.org/W2089544417","https://openalex.org/W2093495014","https://openalex.org/W2095512232","https://openalex.org/W2100837269","https://openalex.org/W2141122084","https://openalex.org/W2146855233","https://openalex.org/W2168555748","https://openalex.org/W2401085762","https://openalex.org/W2472926751","https://openalex.org/W6639002394","https://openalex.org/W6671052312"],"related_works":["https://openalex.org/W2089316165","https://openalex.org/W2004564867","https://openalex.org/W2086038853","https://openalex.org/W2079916236","https://openalex.org/W1993529267","https://openalex.org/W2055207073","https://openalex.org/W2288602395","https://openalex.org/W2060250165","https://openalex.org/W1972487349","https://openalex.org/W2093495014"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}