{"id":"https://openalex.org/W20406259","doi":null,"title":"Agentes antif\u00fangicos. Generalidades","display_name":"Agentes antif\u00fangicos. Generalidades","publication_year":2001,"publication_date":"2001-01-01","ids":{"openalex":"https://openalex.org/W20406259","mag":"20406259"},"language":"es","primary_location":{"id":"pmh:oai:revista.cnic.cu:article/1342","doi":null,"is_oa":true,"landing_page_url":"https://revista.cnic.edu.cu/index.php/RevBiol/article/view/1342","pdf_url":null,"source":{"id":"https://openalex.org/S4306526263","display_name":"Revista CENIC. Ciencias biol\u00f3gicas","issn_l":"0253-5688","issn":["0253-5688","2221-2450"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["latindex","scielo"],"host_organization":"https://openalex.org/I4210132269","host_organization_name":"Centro Nacional de Investigaciones Cient\u00edficas","host_organization_lineage":["https://openalex.org/I4210132269"],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"0253-5688","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://revista.cnic.edu.cu/index.php/RevBiol/article/view/1342","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013061400","display_name":"Yanelis Iznaga","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yanelis Iznaga Sosa","raw_affiliation_strings":["Centro de Qu\u00edmica Farmac\u00e9utica, Departamento de Biotecnolog\u00eda, La Habana, Cuba"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro de Qu\u00edmica Farmac\u00e9utica, Departamento de Biotecnolog\u00eda, La Habana, Cuba","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050188532","display_name":"Carlos Vall\u00edn Plous","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carlos Vall\u00edn Plous","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00245748,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"32","issue":"3","first_page":"173","last_page":"177"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.7860999703407288,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.7860999703407288,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12526","display_name":"Antimicrobial agents and applications","score":0.10689999908208847,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11900","display_name":"Fungal Plant Pathogen Control","score":0.06880000233650208,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antifungal-agents","display_name":"antifungal agents","score":0.9950000047683716},{"id":"https://openalex.org/keywords/fungal-infection","display_name":"fungal infection","score":0.8339999914169312},{"id":"https://openalex.org/keywords/antifungal-resistance","display_name":"antifungal resistance","score":0.6110000014305115}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3798251152038574}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:revista.cnic.cu:article/1342","doi":null,"is_oa":true,"landing_page_url":"https://revista.cnic.edu.cu/index.php/RevBiol/article/view/1342","pdf_url":null,"source":{"id":"https://openalex.org/S4306526263","display_name":"Revista CENIC. Ciencias biol\u00f3gicas","issn_l":"0253-5688","issn":["0253-5688","2221-2450"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["latindex","scielo"],"host_organization":"https://openalex.org/I4210132269","host_organization_name":"Centro Nacional de Investigaciones Cient\u00edficas","host_organization_lineage":["https://openalex.org/I4210132269"],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"0253-5688","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:20406259","doi":null,"is_oa":true,"landing_page_url":"https://biblat.unam.mx/es/revista/revista-cenic-ciencias-biologicas/articulo/agentes-antifungicos-generalidades","pdf_url":null,"source":{"id":"https://openalex.org/S4306526263","display_name":"Revista CENIC. Ciencias biol\u00f3gicas","issn_l":"0253-5688","issn":["0253-5688","2221-2450"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["latindex","scielo"],"host_organization":"https://openalex.org/I4210132269","host_organization_name":"Centro Nacional de Investigaciones Cient\u00edficas","host_organization_lineage":["https://openalex.org/I4210132269"],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Revista CENIC. Ciencias biol\u00f3gicas","raw_type":null}],"best_oa_location":{"id":"pmh:oai:revista.cnic.cu:article/1342","doi":null,"is_oa":true,"landing_page_url":"https://revista.cnic.edu.cu/index.php/RevBiol/article/view/1342","pdf_url":null,"source":{"id":"https://openalex.org/S4306526263","display_name":"Revista CENIC. Ciencias biol\u00f3gicas","issn_l":"0253-5688","issn":["0253-5688","2221-2450"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["latindex","scielo"],"host_organization":"https://openalex.org/I4210132269","host_organization_name":"Centro Nacional de Investigaciones Cient\u00edficas","host_organization_lineage":["https://openalex.org/I4210132269"],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"0253-5688","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2913118532","https://openalex.org/W174172687","https://openalex.org/W4291262954","https://openalex.org/W4404286345","https://openalex.org/W2410567410","https://openalex.org/W4231577681","https://openalex.org/W4239354491","https://openalex.org/W2398043051","https://openalex.org/W4290970573","https://openalex.org/W2142037206"],"abstract_inverted_index":{"The":[0,111,129,221,244],"immunocompromised":[1],"patient":[2],"population":[3],"is":[4,188,193,250],"increasing":[5],"every":[6],"year.":[7],"It":[8],"has":[9,144,224],"been":[10],"attributed":[11],"to":[12,54,76,132,146,154,171,260],"the":[13,23,27,89,147,177,197,206,211,216,234,252,255],"increased":[14],"use":[15,143],"of":[16,31,39,149,167,213,236,241,246],"newer":[17],"and":[18,26,45,69,93,124,140,205],"more":[19,227],"effective":[20],"antibacterial":[21],"agents,":[22],"AIDS":[24],"pandemic,":[25],"rapidly":[28],"expanding":[29],"number":[30],"chemically":[32,121],"induced":[33,122],"immunosuppression":[34,123],"patients.":[35,73,110],"As":[36],"a":[37,138,164],"result":[38],"improved":[40],"management":[41],"protocols,":[42],"AIDS,":[43],"cancer,":[44],"transplantation":[46],"populations":[47],"now":[48],"survive":[49],"longer":[50],"andbecome":[51],"highly":[52],"susceptible":[53],"life-threatening":[55],"fungal":[56,80,229],"infections.":[57,175],"Fungi":[58],"are":[59,102,115,136],"emerging":[60],"as":[61,83,99,105],"important":[62],"nosocomial":[63],"pathogens":[64,81],"that":[65],"cause":[66],"severe":[67],"morbidity":[68],"mortality":[70],"in":[71,108,118,125,158,168,173,183,200,209,215],"hospitalized":[72],"In":[74,152],"addition":[75],"Candida":[77],"app.,":[78],"new":[79,222,237,247],"such":[82],"Fusarium":[84],"spp":[85],".,":[86],"Trichosporon":[87],"beigelii,":[88],"zygomycetes,":[90],"dzmatiaceous":[91],"fungi,":[92],"other":[94],"usually":[95],"nonpathogenic":[96],"fungi":[97,114],"recognized":[98,104],"laboratory":[100],"contaminants":[101],"being":[103],"significant":[106,257],"problems":[107],"some":[109],"pathogenic":[112],"opportunistic":[113],"frequently":[116],"found":[117],"patients":[119,126,219],"with":[120,127,182,199,226,254],"AIDS.":[128],"antifungal":[130,185,248],"agents":[131],"treat":[133],"these":[134],"infections":[135],"only":[137],"few":[139],"their":[141],"widespread":[142],"led":[145],"development":[148,235,245],"drug":[150,242],"resistance.":[151,243],"order":[153],"be":[155,232],"useful":[156],"clinically,":[157],"vitro":[159,184,201],"susceptibility":[160,186,202],"testing":[161,203],"should":[162],"give":[163,196],"reliable":[165],"prediction":[166],"vivo":[169],"response":[170],"therapy":[172,214],"human":[174],"Unfortunately,":[176],"evidence":[178],"for":[179,239],"clinical":[180],"correlation":[181],"tests":[187],"limited":[189],"at":[190],"best.":[191],"This":[192],"not":[194],"surprising,":[195],"problema":[198],"methods":[204],"difficulties":[207],"encountered":[208],"interpreting":[210],"outcome":[212],"very":[217],"complex":[218,263],"involved.":[220],"millennium":[223],"begun":[225],"invasive":[228],"infectionsand":[230],"will":[231],"necessary":[233],"strategies":[238],"control":[240],"drugs":[249],"considered":[251],"strategy":[253],"most":[256],"future":[258],"impact":[259],"confront":[261],"this":[262],"problem.":[264]},"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}