{"id":"https://openalex.org/W2039763333","doi":"https://doi.org/10.1016/j.toxrep.2014.03.004","title":"Can TiC nanoparticles produce toxicity in oral administration to rats?","display_name":"Can TiC nanoparticles produce toxicity in oral administration to rats?","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2039763333","doi":"https://doi.org/10.1016/j.toxrep.2014.03.004","mag":"2039763333","pmid":"https://pubmed.ncbi.nlm.nih.gov/28962237","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5598454"},"language":"en","primary_location":{"id":"doi:10.1016/j.toxrep.2014.03.004","doi":"https://doi.org/10.1016/j.toxrep.2014.03.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.toxrep.2014.03.004","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2214750014000109/pdf","source":{"id":"https://openalex.org/S2764757124","display_name":"Toxicology Reports","issn_l":"2214-7500","issn":["2214-7500"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","norway-1","oarl","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicology Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.sciencedirect.com/science/article/pii/S2214750014000109/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089635381","display_name":"Julie Laloy","orcid":"https://orcid.org/0000-0001-9570-6070","observed_orcids":["https://orcid.org/0000-0001-9570-6070"]},"institutions":[{"id":"https://openalex.org/I149768937","display_name":"University of Namur","ror":"https://ror.org/03d1maw17","country_code":"BE","type":"education","lineage":["https://openalex.org/I149768937"]},{"id":"https://openalex.org/I4391767857","display_name":"Namur Research Institute for Life Sciences","ror":"https://ror.org/038bmak92","country_code":"BE","type":"facility","lineage":["https://openalex.org/I149768937","https://openalex.org/I4391767857"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Julie Laloy","raw_affiliation_strings":["Department of Pharmacy, Namur Medicine Drug Innovation Center (NAMEDIC), Belgium","Namur Nanosafety Centre (NNC), NAmur Research Institute for LIfe Sciences (NARILIS), University of Namur (FUNDP), Rue de Bruxelles 61, B-5000 Namur, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Namur Medicine Drug Innovation Center (NAMEDIC), Belgium","institution_ids":[]},{"raw_affiliation_string":"Namur Nanosafety Centre (NNC), NAmur Research Institute for LIfe Sciences (NARILIS), University of Namur (FUNDP), Rue de Bruxelles 61, B-5000 Namur, Belgium","institution_ids":["https://openalex.org/I149768937","https://openalex.org/I4391767857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039427716","display_name":"Omar Lozano","orcid":"https://orcid.org/0000-0003-3156-5779","observed_orcids":["https://orcid.org/0000-0003-3156-5779"]},"institutions":[{"id":"https://openalex.org/I149768937","display_name":"University of Namur","ror":"https://ror.org/03d1maw17","country_code":"BE","type":"education","lineage":["https://openalex.org/I149768937"]},{"id":"https://openalex.org/I4391767857","display_name":"Namur Research Institute for Life Sciences","ror":"https://ror.org/038bmak92","country_code":"BE","type":"facility","lineage":["https://openalex.org/I149768937","https://openalex.org/I4391767857"]}],"countries":["BE"],"is_corresponding":true,"raw_author_name":"Omar Lozano","raw_affiliation_strings":["Namur Nanosafety Centre (NNC), NAmur Research Institute for LIfe Sciences (NARILIS), University of Namur (FUNDP), Rue de Bruxelles 61, B-5000 Namur, Belgium","Research Centre for the Physics of Matter and Radiation (PMR), Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Namur Nanosafety Centre (NNC), NAmur Research Institute for LIfe Sciences (NARILIS), University of Namur (FUNDP), Rue de Bruxelles 61, B-5000 Namur, Belgium","institution_ids":["https://openalex.org/I149768937","https://openalex.org/I4391767857"]},{"raw_affiliation_string":"Research Centre for the Physics of Matter and Radiation (PMR), Belgium","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083709033","display_name":"L\u00fctfiye Alpan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149768937","display_name":"University of Namur","ror":"https://ror.org/03d1maw17","country_code":"BE","type":"education","lineage":["https://openalex.org/I149768937"]},{"id":"https://openalex.org/I4391767857","display_name":"Namur Research Institute for Life Sciences","ror":"https://ror.org/038bmak92","country_code":"BE","type":"facility","lineage":["https://openalex.org/I149768937","https://openalex.org/I4391767857"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"L\u00fctfiye Alpan","raw_affiliation_strings":["Department of Pharmacy, Namur Medicine Drug Innovation Center (NAMEDIC), Belgium","Namur Nanosafety Centre (NNC), NAmur Research Institute for LIfe Sciences (NARILIS), University of Namur (FUNDP), Rue de Bruxelles 61, B-5000 Namur, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Namur Medicine Drug Innovation Center (NAMEDIC), Belgium","institution_ids":[]},{"raw_affiliation_string":"Namur Nanosafety Centre (NNC), NAmur Research Institute for LIfe Sciences (NARILIS), University of Namur (FUNDP), Rue de Bruxelles 61, B-5000 Namur, Belgium","institution_ids":["https://openalex.org/I149768937","https://openalex.org/I4391767857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083608627","display_name":"Jorge Mejia","orcid":"https://orcid.org/0000-0001-7808-1195","observed_orcids":["https://orcid.org/0000-0001-7808-1195"]},"institutions":[{"id":"https://openalex.org/I149768937","display_name":"University of Namur","ror":"https://ror.org/03d1maw17","country_code":"BE","type":"education","lineage":["https://openalex.org/I149768937"]},{"id":"https://openalex.org/I4391767857","display_name":"Namur Research Institute for Life Sciences","ror":"https://ror.org/038bmak92","country_code":"BE","type":"facility","lineage":["https://openalex.org/I149768937","https://openalex.org/I4391767857"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Jorge Mejia","raw_affiliation_strings":["Namur Nanosafety Centre (NNC), NAmur Research Institute for LIfe Sciences (NARILIS), University of Namur (FUNDP), Rue de Bruxelles 61, B-5000 Namur, Belgium","Research Centre for the Physics of Matter and Radiation (PMR), Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Namur Nanosafety Centre (NNC), NAmur Research Institute for LIfe Sciences (NARILIS), University of Namur (FUNDP), Rue de Bruxelles 61, B-5000 Namur, Belgium","institution_ids":["https://openalex.org/I149768937","https://openalex.org/I4391767857"]},{"raw_affiliation_string":"Research Centre for the Physics of Matter and Radiation (PMR), Belgium","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002361830","display_name":"Olivier Toussaint","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149768937","display_name":"University of Namur","ror":"https://ror.org/03d1maw17","country_code":"BE","type":"education","lineage":["https://openalex.org/I149768937"]},{"id":"https://openalex.org/I4391767857","display_name":"Namur Research Institute for Life Sciences","ror":"https://ror.org/038bmak92","country_code":"BE","type":"facility","lineage":["https://openalex.org/I149768937","https://openalex.org/I4391767857"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Olivier Toussaint","raw_affiliation_strings":["Laboratory of Biochemistry and Cellular Biology (URBC), Belgium","Namur Nanosafety Centre (NNC), NAmur Research Institute for LIfe Sciences (NARILIS), University of Namur (FUNDP), Rue de Bruxelles 61, B-5000 Namur, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biochemistry and Cellular Biology (URBC), Belgium","institution_ids":[]},{"raw_affiliation_string":"Namur Nanosafety Centre (NNC), NAmur Research Institute for LIfe Sciences (NARILIS), University of Namur (FUNDP), Rue de Bruxelles 61, B-5000 Namur, Belgium","institution_ids":["https://openalex.org/I149768937","https://openalex.org/I4391767857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110536710","display_name":"Bernard Masereel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149768937","display_name":"University of Namur","ror":"https://ror.org/03d1maw17","country_code":"BE","type":"education","lineage":["https://openalex.org/I149768937"]},{"id":"https://openalex.org/I4391767857","display_name":"Namur Research Institute for Life Sciences","ror":"https://ror.org/038bmak92","country_code":"BE","type":"facility","lineage":["https://openalex.org/I149768937","https://openalex.org/I4391767857"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Bernard Masereel","raw_affiliation_strings":["Department of Pharmacy, Namur Medicine Drug Innovation Center (NAMEDIC), Belgium","Namur Nanosafety Centre (NNC), NAmur Research Institute for LIfe Sciences (NARILIS), University of Namur (FUNDP), Rue de Bruxelles 61, B-5000 Namur, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Namur Medicine Drug Innovation Center (NAMEDIC), Belgium","institution_ids":[]},{"raw_affiliation_string":"Namur Nanosafety Centre (NNC), NAmur Research Institute for LIfe Sciences (NARILIS), University of Namur (FUNDP), Rue de Bruxelles 61, B-5000 Namur, Belgium","institution_ids":["https://openalex.org/I149768937","https://openalex.org/I4391767857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041424887","display_name":"Jean\u2010Michel Dogn\u00e9","orcid":"https://orcid.org/0000-0003-2107-1804","observed_orcids":["https://orcid.org/0000-0003-2107-1804"]},"institutions":[{"id":"https://openalex.org/I149768937","display_name":"University of Namur","ror":"https://ror.org/03d1maw17","country_code":"BE","type":"education","lineage":["https://openalex.org/I149768937"]},{"id":"https://openalex.org/I4391767857","display_name":"Namur Research Institute for Life Sciences","ror":"https://ror.org/038bmak92","country_code":"BE","type":"facility","lineage":["https://openalex.org/I149768937","https://openalex.org/I4391767857"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Jean-Michel Dogn\u00e9","raw_affiliation_strings":["Department of Pharmacy, Namur Medicine Drug Innovation Center (NAMEDIC), Belgium","Namur Nanosafety Centre (NNC), NAmur Research Institute for LIfe Sciences (NARILIS), University of Namur (FUNDP), Rue de Bruxelles 61, B-5000 Namur, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Namur Medicine Drug Innovation Center (NAMEDIC), Belgium","institution_ids":[]},{"raw_affiliation_string":"Namur Nanosafety Centre (NNC), NAmur Research Institute for LIfe Sciences (NARILIS), University of Namur (FUNDP), Rue de Bruxelles 61, B-5000 Namur, Belgium","institution_ids":["https://openalex.org/I149768937","https://openalex.org/I4391767857"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059869587","display_name":"St\u00e9phane Lucas","orcid":"https://orcid.org/0000-0003-3229-9855","observed_orcids":["https://orcid.org/0000-0003-3229-9855"]},"institutions":[{"id":"https://openalex.org/I149768937","display_name":"University of Namur","ror":"https://ror.org/03d1maw17","country_code":"BE","type":"education","lineage":["https://openalex.org/I149768937"]},{"id":"https://openalex.org/I4391767857","display_name":"Namur Research Institute for Life Sciences","ror":"https://ror.org/038bmak92","country_code":"BE","type":"facility","lineage":["https://openalex.org/I149768937","https://openalex.org/I4391767857"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"St\u00e9phane Lucas","raw_affiliation_strings":["Namur Nanosafety Centre (NNC), NAmur Research Institute for LIfe Sciences (NARILIS), University of Namur (FUNDP), Rue de Bruxelles 61, B-5000 Namur, Belgium","Research Centre for the Physics of Matter and Radiation (PMR), Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Namur Nanosafety Centre (NNC), NAmur Research Institute for LIfe Sciences (NARILIS), University of Namur (FUNDP), Rue de Bruxelles 61, B-5000 Namur, Belgium","institution_ids":["https://openalex.org/I149768937","https://openalex.org/I4391767857"]},{"raw_affiliation_string":"Research Centre for the Physics of Matter and Radiation (PMR), Belgium","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5039427716"],"corresponding_institution_ids":["https://openalex.org/I149768937","https://openalex.org/I4391767857"],"apc_list":{"value":2530,"currency":"USD","value_usd":2530},"apc_paid":{"value":2530,"currency":"USD","value_usd":2530},"fwci":1.347,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.79185159,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"1","issue":null,"first_page":"172","last_page":"187"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10079","display_name":"Nanoparticles: synthesis and applications","score":0.8949999809265137,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10079","display_name":"Nanoparticles: synthesis and applications","score":0.8949999809265137,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.06629999727010727,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":0.00860000029206276,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/titanium-carbide-nanoparticles","display_name":"titanium carbide nanoparticles","score":0.9869999885559082},{"id":"https://openalex.org/keywords/nanoparticle-toxicity","display_name":"nanoparticle toxicity","score":0.8870000243186951},{"id":"https://openalex.org/keywords/oral-administration","display_name":"oral administration","score":0.8500000238418579},{"id":"https://openalex.org/keywords/acute-toxicity","display_name":"acute toxicity","score":0.9070000052452087},{"id":"https://openalex.org/keywords/subacute-toxicity","display_name":"subacute toxicity","score":0.9919999837875366},{"id":"https://openalex.org/keywords/toxicokinetics","display_name":"toxicokinetics","score":0.972000002861023},{"id":"https://openalex.org/keywords/toxicodynamics","display_name":"toxicodynamics","score":0.9160000085830688},{"id":"https://openalex.org/keywords/histopathology","display_name":"histopathology","score":0.7409999966621399},{"id":"https://openalex.org/keywords/alkaline-phosphatase","display_name":"alkaline phosphatase","score":0.9100000262260437},{"id":"https://openalex.org/keywords/aspartate-aminotransferase","display_name":"aspartate aminotransferase","score":0.8600000143051147},{"id":"https://openalex.org/keywords/bile-salts","display_name":"bile salts","score":0.8659999966621399},{"id":"https://openalex.org/keywords/mineral-absorption","display_name":"mineral absorption","score":0.7289999723434448},{"id":"https://openalex.org/keywords/fecal-excretion","display_name":"fecal excretion","score":0.9710000157356262},{"id":"https://openalex.org/keywords/urinary-excretion","display_name":"urinary excretion","score":0.796999990940094},{"id":"https://openalex.org/keywords/intestinal-permeability","display_name":"intestinal permeability","score":0.7269999980926514}],"concepts":[{"id":"https://openalex.org/C195289149","wikidata":"https://www.wikidata.org/wiki/Q2256694","display_name":"Toxicokinetics","level":3,"score":0.6963101625442505},{"id":"https://openalex.org/C2780026642","wikidata":"https://www.wikidata.org/wiki/Q40924","display_name":"Urine","level":2,"score":0.6793054342269897},{"id":"https://openalex.org/C2777056448","wikidata":"https://www.wikidata.org/wiki/Q285166","display_name":"Oral administration","level":2,"score":0.6791458129882812},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.6366640329360962},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5995755791664124},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.575354814529419},{"id":"https://openalex.org/C10146269","wikidata":"https://www.wikidata.org/wiki/Q185557","display_name":"Excretion","level":2,"score":0.5225845575332642},{"id":"https://openalex.org/C2780931953","wikidata":"https://www.wikidata.org/wiki/Q9371","display_name":"Spleen","level":2,"score":0.47159135341644287},{"id":"https://openalex.org/C116263406","wikidata":"https://www.wikidata.org/wiki/Q3299024","display_name":"Acute toxicity","level":3,"score":0.4693290591239929},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.4570266604423523},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2892046570777893},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2691730260848999},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.19367268681526184},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1016/j.toxrep.2014.03.004","doi":"https://doi.org/10.1016/j.toxrep.2014.03.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.toxrep.2014.03.004","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2214750014000109/pdf","source":{"id":"https://openalex.org/S2764757124","display_name":"Toxicology Reports","issn_l":"2214-7500","issn":["2214-7500"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","norway-1","oarl","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicology Reports","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4538057","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5598454","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:28962237","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28962237","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicology reports","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5598454","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5598454/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicol Rep","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:87fe9624b0be426ebfb9bf4566558389","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/87fe9624b0be426ebfb9bf4566558389","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Toxicology Reports, Vol 1, Iss C, Pp 172-187 (2014)","raw_type":"article"},{"id":"pmh:oai:pure.unamur.be:openaire_cris_publications/a5948390-d2b5-4dca-9804-340274ac4233","doi":null,"is_oa":false,"landing_page_url":"https://researchportal.unamur.be/en/publications/a5948390-d2b5-4dca-9804-340274ac4233","pdf_url":null,"source":{"id":"https://openalex.org/S4406922457","display_name":"Repository of the University of Namur","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Laloy, J, Lozano Garcia, O, Alpan, L, Mejia Mendoza, J H, Toussaint, O, Masereel, B, Dogn\u00e9, J-M & Lucas, S 2014, 'Can TiC nanoparticles produce toxicity in oral administration to rats?', Toxicology Reports, vol. 1, pp. 172-187. https://doi.org/10.1016/j.toxrep.2014.03.004","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.toxrep.2014.03.004","doi":"https://doi.org/10.1016/j.toxrep.2014.03.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.toxrep.2014.03.004","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2214750014000109/pdf","source":{"id":"https://openalex.org/S2764757124","display_name":"Toxicology Reports","issn_l":"2214-7500","issn":["2214-7500"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","norway-1","oarl","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicology Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1468913444","display_name":"A pan-European infrastructure for quality in nanomaterials safety testing","funder_award_id":"262163","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320309739","display_name":"Fondation du Juda\u00efsme de Belgique","ror":null},{"id":"https://openalex.org/F4320314181","display_name":"Universitaire Stichting","ror":"https://ror.org/001t02e86"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320325905","display_name":"Service Public de Wallonie","ror":"https://ror.org/0215gxf82"},{"id":"https://openalex.org/F4320338290","display_name":"National Renewable Energy Laboratory","ror":"https://ror.org/036266993"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2039763333.pdf","grobid_xml":"https://content.openalex.org/works/W2039763333.grobid-xml"},"referenced_works_count":55,"referenced_works":["https://openalex.org/W102942757","https://openalex.org/W560592272","https://openalex.org/W1489018618","https://openalex.org/W1498906629","https://openalex.org/W1513870450","https://openalex.org/W1593211822","https://openalex.org/W1963804750","https://openalex.org/W1969992824","https://openalex.org/W1973362837","https://openalex.org/W1973813414","https://openalex.org/W1978663053","https://openalex.org/W1982554116","https://openalex.org/W1985230897","https://openalex.org/W1996903255","https://openalex.org/W2014239748","https://openalex.org/W2016009059","https://openalex.org/W2018206804","https://openalex.org/W2026634412","https://openalex.org/W2027850104","https://openalex.org/W2027895492","https://openalex.org/W2035206741","https://openalex.org/W2036145275","https://openalex.org/W2038246612","https://openalex.org/W2040170408","https://openalex.org/W2042795875","https://openalex.org/W2048405693","https://openalex.org/W2051007957","https://openalex.org/W2053694215","https://openalex.org/W2055870216","https://openalex.org/W2063893585","https://openalex.org/W2065104829","https://openalex.org/W2072119012","https://openalex.org/W2081489312","https://openalex.org/W2082172510","https://openalex.org/W2085151797","https://openalex.org/W2088081110","https://openalex.org/W2090107650","https://openalex.org/W2100168611","https://openalex.org/W2117326659","https://openalex.org/W2125539459","https://openalex.org/W2130969801","https://openalex.org/W2132915215","https://openalex.org/W2140720810","https://openalex.org/W2145213934","https://openalex.org/W2155118487","https://openalex.org/W2158558808","https://openalex.org/W2168854889","https://openalex.org/W2276430610","https://openalex.org/W2411786840","https://openalex.org/W2482979731","https://openalex.org/W2924018592","https://openalex.org/W4244450487","https://openalex.org/W4253946060","https://openalex.org/W4255760236","https://openalex.org/W7066861539"],"related_works":["https://openalex.org/W1973813414","https://openalex.org/W2887286449","https://openalex.org/W2062093556","https://openalex.org/W2217462440","https://openalex.org/W2147033192","https://openalex.org/W4381433725","https://openalex.org/W4287861980","https://openalex.org/W2256786012","https://openalex.org/W2790438483","https://openalex.org/W4386712758"],"abstract_inverted_index":{"Titanium":[0],"carbide":[1],"(TiC)":[2],"is":[3,13],"used":[4],"for":[5,18],"ceramic":[6],"metal":[7],"composites":[8],"in":[9,29,48,52,102,132,147,163,168,188,203,213],"several":[10],"industries":[11],"and":[12,20,43,56,70,79,91,114,123],"regarded":[14],"as":[15,183],"a":[16],"nanomaterial":[17],"catalyst":[19],"battery":[21],"applications.":[22],"However,":[23],"there":[24],"are":[25],"very":[26],"few":[27],"studies":[28],"regard":[30],"to":[31],"the":[32,41,74,94,106,180,220],"toxicological":[33],"potential":[34],"of":[35,45,96,142,192],"TiC":[36,46,143,152,177,184,199,217],"nanoparticles":[37],"(NPs).":[38],"To":[39],"study":[40],"toxicodynamics":[42],"toxicokinetics":[44],"NPs":[47],"Sprague":[49],"Dawley":[50],"rats":[51],"acute":[53,63,107],"(24":[54],"h)":[55],"subacute":[57,75,164],"(28":[58],"days)":[59],"oral":[60,197],"administrations.":[61],"The":[62],"doses":[64,76],"were":[65,77,138,186,211],"0.5,":[66],"5,":[67],"50,":[68],"300":[69,113],"1000":[71,115],"mg":[72,81,116,121,128],"kg\u22121;":[73],"0.5":[78],"50":[80],"kg\u22121.":[82],"Organ":[83],"histopathological":[84],"examination":[85],"(esophagus,":[86],"stomach,":[87],"intestines,":[88],"spleen,":[89,150],"liver,":[90],"kidneys)":[92],"indicates":[93],"absence":[95],"damage":[97],"at":[98],"all":[99],"applied":[100],"doses,":[101],"both":[103],"assessments.":[104],"In":[105],"administration,":[108,162],"alkaline":[109],"phosphatases":[110],"increased":[111,119],"(5,":[112],"kg\u22121),":[117],"ASAT":[118],"(1000":[120],"kg\u22121)":[122],"bile":[124],"salts":[125],"decreased":[126],"(0.5":[127],"kg\u22121).":[129],"No":[130,190],"alterations":[131],"urine":[133],"parameters":[134],"(sodium,":[135],"potassium,":[136],"osmolarity)":[137],"found.":[139],"Acute":[140],"administration":[141,165],"caused":[144],"mineral":[145,169,206],"changes":[146],"organs":[148],"(liver,":[149],"kidneys).":[151],"was":[153,194,200],"mostly":[154,202],"cleared":[155],"by":[156],"feces":[157,204],"excretion":[158],"24":[159],"h":[160],"after":[161,196],"causing":[166],"variations":[167],"absorption":[170,207],"(Mg,":[171],"Al,":[172],"P,":[173],"S,":[174],"Ca,":[175],"Zn).":[176],"could":[178],"pass":[179],"intestinal":[181,221],"barrier":[182],"traces":[185,210],"detected":[187],"urine.":[189],"sign":[191],"toxicity":[193],"found":[195],"administration.":[198],"excreted":[201],"producing":[205],"alterations.":[208],"Low":[209],"retrieved":[212],"urine,":[214],"indicating":[215],"that":[216],"can":[218],"cross":[219],"barrier.":[222]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":5}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}