{"id":"https://openalex.org/W2039354575","doi":"https://doi.org/10.1016/j.ajog.2007.11.054","title":"Postovariectomy weight gain in female rats is reversed by estrogen receptor \u03b1 agonist, propylpyrazoletriol","display_name":"Postovariectomy weight gain in female rats is reversed by estrogen receptor \u03b1 agonist, propylpyrazoletriol","publication_year":2008,"publication_date":"2008-02-05","ids":{"openalex":"https://openalex.org/W2039354575","doi":"https://doi.org/10.1016/j.ajog.2007.11.054","mag":"2039354575","pmid":"https://pubmed.ncbi.nlm.nih.gov/18241818"},"language":"en","primary_location":{"id":"doi:10.1016/j.ajog.2007.11.054","doi":"https://doi.org/10.1016/j.ajog.2007.11.054","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ajog.2007.11.054","pdf_url":null,"source":{"id":"https://openalex.org/S122347013","display_name":"American Journal of Obstetrics and Gynecology","issn_l":"0002-9378","issn":["0002-9378","1085-8709","1097-6868"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Obstetrics and Gynecology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063689427","display_name":"Iga Wegorzewska","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I148314036","display_name":"Uniformed Services University of the Health Sciences","ror":"https://ror.org/04r3kq386","country_code":"US","type":"education","lineage":["https://openalex.org/I148314036"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Iga N. Wegorzewska","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA","Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA","institution_ids":["https://openalex.org/I148314036"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, MD","institution_ids":["https://openalex.org/I148314036"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049390330","display_name":"Katy Walters","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I148314036","display_name":"Uniformed Services University of the Health Sciences","ror":"https://ror.org/04r3kq386","country_code":"US","type":"education","lineage":["https://openalex.org/I148314036"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katy Walters","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, MD","institution_ids":["https://openalex.org/I148314036"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068433317","display_name":"Michael James Weiser","orcid":"https://orcid.org/0009-0002-8528-4024","observed_orcids":["https://orcid.org/0009-0002-8528-4024"]},"institutions":[{"id":"https://openalex.org/I92446798","display_name":"Colorado State University","ror":"https://ror.org/03k1gpj17","country_code":"US","type":"education","lineage":["https://openalex.org/I92446798"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael J. Weiser","raw_affiliation_strings":["Department of Biomedical Sciences, Colorado State University, Fort Collins, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, Colorado State University, Fort Collins, CO","institution_ids":["https://openalex.org/I92446798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039172756","display_name":"Danette F Cruthirds","orcid":"https://orcid.org/0000-0003-1838-6821","observed_orcids":["https://orcid.org/0000-0003-1838-6821"]},"institutions":[{"id":"https://openalex.org/I148314036","display_name":"Uniformed Services University of the Health Sciences","ror":"https://ror.org/04r3kq386","country_code":"US","type":"education","lineage":["https://openalex.org/I148314036"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Danette F. Cruthirds","raw_affiliation_strings":["Program in Neuroscience, Uniformed Services University of the Health Sciences, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Program in Neuroscience, Uniformed Services University of the Health Sciences, Bethesda, MD","institution_ids":["https://openalex.org/I148314036"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077201350","display_name":"Emily Ewell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I148314036","display_name":"Uniformed Services University of the Health Sciences","ror":"https://ror.org/04r3kq386","country_code":"US","type":"education","lineage":["https://openalex.org/I148314036"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emily Ewell","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, MD","institution_ids":["https://openalex.org/I148314036"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038665314","display_name":"Darwin O. Larco","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I148314036","display_name":"Uniformed Services University of the Health Sciences","ror":"https://ror.org/04r3kq386","country_code":"US","type":"education","lineage":["https://openalex.org/I148314036"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Darwin O. Larco","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, MD","institution_ids":["https://openalex.org/I148314036"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042132328","display_name":"Robert J. Handa","orcid":"https://orcid.org/0000-0001-9131-2808","observed_orcids":["https://orcid.org/0000-0001-9131-2808"]},"institutions":[{"id":"https://openalex.org/I92446798","display_name":"Colorado State University","ror":"https://ror.org/03k1gpj17","country_code":"US","type":"education","lineage":["https://openalex.org/I92446798"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Robert J. Handa","raw_affiliation_strings":["Department of Biomedical Sciences, Colorado State University, Fort Collins, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, Colorado State University, Fort Collins, CO","institution_ids":["https://openalex.org/I92446798"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046082760","display_name":"T. John Wu","orcid":"https://orcid.org/0000-0002-8274-0226","observed_orcids":["https://orcid.org/0000-0002-8274-0226"]},"institutions":[{"id":"https://openalex.org/I148314036","display_name":"Uniformed Services University of the Health Sciences","ror":"https://ror.org/04r3kq386","country_code":"US","type":"education","lineage":["https://openalex.org/I148314036"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"T. John Wu","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, MD","Program in Neuroscience, Uniformed Services University of the Health Sciences, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, MD","institution_ids":["https://openalex.org/I148314036"]},{"raw_affiliation_string":"Program in Neuroscience, Uniformed Services University of the Health Sciences, Bethesda, MD","institution_ids":["https://openalex.org/I148314036"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5042132328","https://openalex.org/A5046082760"],"corresponding_institution_ids":["https://openalex.org/I148314036","https://openalex.org/I92446798"],"apc_list":{"value":5410,"currency":"USD","value_usd":5410},"apc_paid":null,"fwci":2.5014,"has_fulltext":false,"cited_by_count":57,"citation_normalized_percentile":{"value":0.87484144,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"199","issue":"1","first_page":"67.e1","last_page":"67.e5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/postmenopausal-weight-gain","display_name":"postmenopausal weight gain","score":0.9179999828338623},{"id":"https://openalex.org/keywords/estrogen-receptor-alpha","display_name":"estrogen receptor alpha","score":0.9490000009536743},{"id":"https://openalex.org/keywords/estrogen-receptor-beta","display_name":"estrogen receptor beta","score":0.9340000152587891},{"id":"https://openalex.org/keywords/diarylpropionitrile","display_name":"diarylpropionitrile","score":0.9629999995231628},{"id":"https://openalex.org/keywords/estradiol","display_name":"estradiol","score":0.8190000057220459},{"id":"https://openalex.org/keywords/ovariectomy","display_name":"ovariectomy","score":0.9710000157356262},{"id":"https://openalex.org/keywords/adrenalectomy","display_name":"adrenalectomy","score":0.9610000252723694},{"id":"https://openalex.org/keywords/body-weight-regulation","display_name":"body weight regulation","score":0.9860000014305115},{"id":"https://openalex.org/keywords/menopause","display_name":"menopause","score":0.5289999842643738},{"id":"https://openalex.org/keywords/female-rats","display_name":"female rats","score":0.6520000100135803}],"concepts":[{"id":"https://openalex.org/C8264082","wikidata":"https://www.wikidata.org/wiki/Q7113259","display_name":"Ovariectomized rat","level":3,"score":0.9908020496368408},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.852200448513031},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8446342945098877},{"id":"https://openalex.org/C2778938600","wikidata":"https://www.wikidata.org/wiki/Q389934","display_name":"Agonist","level":3,"score":0.814136803150177},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.7010903358459473},{"id":"https://openalex.org/C2780320433","wikidata":"https://www.wikidata.org/wiki/Q3403879","display_name":"Weight gain","level":3,"score":0.6656104922294617},{"id":"https://openalex.org/C84606932","wikidata":"https://www.wikidata.org/wiki/Q416496","display_name":"Estrogen receptor","level":4,"score":0.6342922449111938},{"id":"https://openalex.org/C2778562196","wikidata":"https://www.wikidata.org/wiki/Q177708","display_name":"Menopause","level":2,"score":0.5745521187782288},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5672363042831421},{"id":"https://openalex.org/C147583825","wikidata":"https://www.wikidata.org/wiki/Q620876","display_name":"Body weight","level":2,"score":0.49122852087020874},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.39385145902633667},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.0},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004958","descriptor_name":"Estradiol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004967","descriptor_name":"Estrogens","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009570","descriptor_name":"Nitriles","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D010052","descriptor_name":"Ovariectomy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D010636","descriptor_name":"Phenols","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011422","descriptor_name":"Propionates","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011720","descriptor_name":"Pyrazoles","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011960","descriptor_name":"Receptors, Estrogen","qualifier_ui":"Q000819","qualifier_name":"agonists","is_major_topic":true},{"descriptor_ui":"D015430","descriptor_name":"Weight Gain","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D020318","descriptor_name":"Rats, Long-Evans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D047628","descriptor_name":"Estrogen Receptor alpha","qualifier_ui":"Q000819","qualifier_name":"agonists","is_major_topic":false},{"descriptor_ui":"D047629","descriptor_name":"Estrogen Receptor beta","qualifier_ui":"Q000819","qualifier_name":"agonists","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.ajog.2007.11.054","doi":"https://doi.org/10.1016/j.ajog.2007.11.054","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ajog.2007.11.054","pdf_url":null,"source":{"id":"https://openalex.org/S122347013","display_name":"American Journal of Obstetrics and Gynecology","issn_l":"0002-9378","issn":["0002-9378","1085-8709","1097-6868"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Obstetrics and Gynecology","raw_type":"journal-article"},{"id":"pmid:18241818","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18241818","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of obstetrics and gynecology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6878326100","display_name":"Gonadal Steroid Receptors and the Hypothalamo-Pituitary-Adrenal Axis","funder_award_id":"R01NS039951","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W1931314520","https://openalex.org/W1983538594","https://openalex.org/W1993337971","https://openalex.org/W1995304164","https://openalex.org/W1996369704","https://openalex.org/W1998000672","https://openalex.org/W2003656057","https://openalex.org/W2007975243","https://openalex.org/W2009089225","https://openalex.org/W2011735277","https://openalex.org/W2012425172","https://openalex.org/W2012888249","https://openalex.org/W2017886735","https://openalex.org/W2022965804","https://openalex.org/W2026809533","https://openalex.org/W2054303348","https://openalex.org/W2063248917","https://openalex.org/W2066962102","https://openalex.org/W2073353512","https://openalex.org/W2084984267","https://openalex.org/W2088776165","https://openalex.org/W2088993196","https://openalex.org/W2091428616","https://openalex.org/W2092411075","https://openalex.org/W2108881204","https://openalex.org/W2111619727","https://openalex.org/W2113572311","https://openalex.org/W2113576333","https://openalex.org/W2129599776","https://openalex.org/W2136600170","https://openalex.org/W2162934389","https://openalex.org/W2165265831","https://openalex.org/W2469229070"],"related_works":["https://openalex.org/W1983538594","https://openalex.org/W2150712481","https://openalex.org/W2138783241","https://openalex.org/W2069025915","https://openalex.org/W4391155118","https://openalex.org/W7016660613","https://openalex.org/W1987890077","https://openalex.org/W822926353","https://openalex.org/W1568590340","https://openalex.org/W2624407369"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}